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Items: 1 to 50 of 56

1.

Optimisation of template preparation and laboratory evaluation of the Loopamp™ Trypanosoma brucei kit for detection of parasite DNA in blood.

Matovu E, Katiti D, Kitibwa A, Kazibwe A, Kato CD, Biéler S, Ndung'u JM.

Exp Parasitol. 2020 Feb 29;211:107844. doi: 10.1016/j.exppara.2020.107844. [Epub ahead of print]

PMID:
32119932
2.

Laboratory Diagnosis of Buruli Ulcer: Challenges and Future Perspectives.

Röltgen K, Cruz I, Ndung’u JM, Pluschke G.

In: Pluschke G, Röltgen K, editors. Buruli Ulcer: Mycobacterium Ulcerans Disease [Internet]. Cham (CH): Springer; 2019.
2019 Apr 30.

3.

Haemoparasitic Infections in Cattle from a Trypanosoma brucei Rhodesiense Sleeping Sickness Endemic District of Eastern Uganda.

Matovu E, Mugasa CM, Waiswa P, Kitibwa A, Boobo A, Ndung'u JM.

Trop Med Infect Dis. 2020 Feb 7;5(1). pii: E24. doi: 10.3390/tropicalmed5010024.

4.

Assessing the impact of aggregating disease stage data in model predictions of human African trypanosomiasis transmission and control activities in Bandundu province (DRC).

Castaño MS, Ndeffo-Mbah ML, Rock KS, Palmer C, Knock E, Mwamba Miaka E, Ndung'u JM, Torr S, Verlé P, Spencer SEF, Galvani A, Bever C, Keeling MJ, Chitnis N.

PLoS Negl Trop Dis. 2020 Jan 21;14(1):e0007976. doi: 10.1371/journal.pntd.0007976. eCollection 2020 Jan.

5.

Neopterin and CXCL-13 in Diagnosis and Follow-Up of Trypanosoma brucei gambiense Sleeping Sickness: Lessons from the Field in Angola.

Bonnet J, Vignoles P, Tiberti N, Gedeão V, Hainard A, Turck N, Josenando T, Ndung'u JM, Sanchez JC, Courtioux B, Bisser S.

Biomed Res Int. 2019 Nov 23;2019:6070176. doi: 10.1155/2019/6070176. eCollection 2019.

6.

Access to prompt diagnosis: The missing link in preventing mental health disorders associated with neglected tropical diseases.

Picado A, Nogaro S, Cruz I, Biéler S, Ruckstuhl L, Bastow J, Ndung'u JM.

PLoS Negl Trop Dis. 2019 Oct 17;13(10):e0007679. doi: 10.1371/journal.pntd.0007679. eCollection 2019 Oct. No abstract available.

7.

Target Product Profile for a point-of-care diagnostic test for dermal leishmaniases.

Cruz I, Albertini A, Barbeitas M, Arana B, Picado A, Ruiz-Postigo JA, Ndung'u JM.

Parasite Epidemiol Control. 2019 Mar 7;5:e00103. doi: 10.1016/j.parepi.2019.e00103. eCollection 2019 May.

8.

The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America.

Picado A, Cruz I, Redard-Jacot M, Schijman AG, Torrico F, Sosa-Estani S, Katz Z, Ndung'u JM.

BMJ Glob Health. 2018 Oct 11;3(5):e001069. doi: 10.1136/bmjgh-2018-001069. eCollection 2018.

9.

Knowledge, attitudes and practices about human African trypanosomiasis and their implications in designing intervention strategies for Yei county, South Sudan.

Bukachi SA, Mumbo AA, Alak ACD, Sebit W, Rumunu J, Biéler S, Ndung'u JM.

PLoS Negl Trop Dis. 2018 Oct 1;12(10):e0006826. doi: 10.1371/journal.pntd.0006826. eCollection 2018 Oct.

10.

Cost-effectiveness of using a rapid diagnostic test to screen for human African trypanosomiasis in the Democratic Republic of the Congo.

Bessell PR, Lumbala C, Lutumba P, Baloji S, Biéler S, Ndung'u JM.

PLoS One. 2018 Sep 21;13(9):e0204335. doi: 10.1371/journal.pone.0204335. eCollection 2018.

11.

Assessing Strategies Against Gambiense Sleeping Sickness Through Mathematical Modeling.

Rock KS, Ndeffo-Mbah ML, Castaño S, Palmer C, Pandey A, Atkins KE, Ndung'u JM, Hollingsworth TD, Galvani A, Bever C, Chitnis N, Keeling MJ.

Clin Infect Dis. 2018 Jun 1;66(suppl_4):S286-S292. doi: 10.1093/cid/ciy018.

12.

Development and Evaluation of a Novel Loop-Mediated Isothermal Amplification Assay for Diagnosis of Cutaneous and Visceral Leishmaniasis.

Adams ER, Schoone G, Versteeg I, Gomez MA, Diro E, Mori Y, Perlee D, Downing T, Saravia N, Assaye A, Hailu A, Albertini A, Ndung'u JM, Schallig H.

J Clin Microbiol. 2018 Jun 25;56(7). pii: e00386-18. doi: 10.1128/JCM.00386-18. Print 2018 Jul.

13.

Prospective evaluation of a rapid diagnostic test for Trypanosoma brucei gambiense infection developed using recombinant antigens.

Lumbala C, Biéler S, Kayembe S, Makabuza J, Ongarello S, Ndung'u JM.

PLoS Negl Trop Dis. 2018 Mar 28;12(3):e0006386. doi: 10.1371/journal.pntd.0006386. eCollection 2018 Mar.

14.

Sensitive and less invasive confirmatory diagnosis of visceral leishmaniasis in Sudan using loop-mediated isothermal amplification (LAMP).

Mukhtar M, Ali SS, Boshara SA, Albertini A, Monnerat S, Bessell P, Mori Y, Kubota Y, Ndung'u JM, Cruz I.

PLoS Negl Trop Dis. 2018 Feb 14;12(2):e0006264. doi: 10.1371/journal.pntd.0006264. eCollection 2018 Feb.

15.

Serological tests for gambiense human African trypanosomiasis detect antibodies in cattle.

Matovu E, Kitibwa A, Picado A, Biéler S, Bessell PR, Ndung'u JM.

Parasit Vectors. 2017 Nov 3;10(1):546. doi: 10.1186/s13071-017-2487-8.

16.

Enhanced passive screening and diagnosis for gambiense human African trypanosomiasis in north-western Uganda - Moving towards elimination.

Wamboga C, Matovu E, Bessell PR, Picado A, Biéler S, Ndung'u JM.

PLoS One. 2017 Oct 12;12(10):e0186429. doi: 10.1371/journal.pone.0186429. eCollection 2017.

17.

Analytical sensitivity and specificity of a loop-mediated isothermal amplification (LAMP) kit prototype for detection of Trypanosoma cruzi DNA in human blood samples.

Besuschio SA, Llano Murcia M, Benatar AF, Monnerat S, Cruz I, Picado A, Curto MLÁ, Kubota Y, Wehrendt DP, Pavia P, Mori Y, Puerta C, Ndung'u JM, Schijman AG.

PLoS Negl Trop Dis. 2017 Jul 20;11(7):e0005779. doi: 10.1371/journal.pntd.0005779. eCollection 2017 Jul.

18.

Performance of the SD BIOLINE® HAT rapid test in various diagnostic algorithms for gambiense human African trypanosomiasis in the Democratic Republic of the Congo.

Lumbala C, Bessell PR, Lutumba P, Baloji S, Biéler S, Ndung'u JM.

PLoS One. 2017 Jul 3;12(7):e0180555. doi: 10.1371/journal.pone.0180555. eCollection 2017.

19.

Metabolomics Identifies Multiple Candidate Biomarkers to Diagnose and Stage Human African Trypanosomiasis.

Vincent IM, Daly R, Courtioux B, Cattanach AM, Biéler S, Ndung'u JM, Bisser S, Barrett MP.

PLoS Negl Trop Dis. 2016 Dec 12;10(12):e0005140. doi: 10.1371/journal.pntd.0005140. eCollection 2016 Dec.

20.

Evaluation of Antigens for Development of a Serological Test for Human African Trypanosomiasis.

Biéler S, Waltenberger H, Barrett MP, McCulloch R, Mottram JC, Carrington M, Schwaeble W, McKerrow J, Phillips MA, Michels PA, Büscher P, Sanchez JC, Bishop R, Robinson DR, Bangs J, Ferguson M, Nerima B, Albertini A, Michel G, Radwandska M, Ndung'u JM.

PLoS One. 2016 Dec 9;11(12):e0168074. doi: 10.1371/journal.pone.0168074. eCollection 2016.

21.

Sensitivity and Specificity of a Prototype Rapid Diagnostic Test for the Detection of Trypanosoma brucei gambiense Infection: A Multi-centric Prospective Study.

Bisser S, Lumbala C, Nguertoum E, Kande V, Flevaud L, Vatunga G, Boelaert M, Büscher P, Josenando T, Bessell PR, Biéler S, Ndung'u JM.

PLoS Negl Trop Dis. 2016 Apr 8;10(4):e0004608. doi: 10.1371/journal.pntd.0004608. eCollection 2016 Apr.

22.

Illuminating the Prevalence of Trypanosoma brucei s.l. in Glossina Using LAMP as a Tool for Xenomonitoring.

Cunningham LJ, Lingley JK, Haines LR, Ndung'u JM, Torr SJ, Adams ER.

PLoS Negl Trop Dis. 2016 Feb 18;10(2):e0004441. doi: 10.1371/journal.pntd.0004441. eCollection 2016 Feb.

23.

Evaluation of the diagnostic accuracy of prototype rapid tests for human African trypanosomiasis.

Sternberg JM, Gierliński M, Biéler S, Ferguson MA, Ndung'u JM.

PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3373. doi: 10.1371/journal.pntd.0003373. eCollection 2014 Dec. Erratum in: PLoS Negl Trop Dis. 2015 Mar;9(3):e0003613.

24.

Kenya Trypanosomiasis Research Institute cryobank for human and animal trypanosome isolates to support research: opportunities and challenges.

Murilla GA, Ndung'u K, Thuita JK, Gitonga PK, Kahiga DT, Auma JE, Ouma JO, Rutto JJ, Ndung'u JM.

PLoS Negl Trop Dis. 2014 May 22;8(5):e2747. doi: 10.1371/journal.pntd.0002747. eCollection 2014 May. No abstract available.

25.

Neopterin is a cerebrospinal fluid marker for treatment outcome evaluation in patients affected by Trypanosoma brucei gambiense sleeping sickness.

Tiberti N, Lejon V, Hainard A, Courtioux B, Robin X, Turck N, Kristensson K, Matovu E, Enyaru JC, Mumba Ngoyi D, Krishna S, Bisser S, Ndung'u JM, Büscher P, Sanchez JC.

PLoS Negl Trop Dis. 2013;7(2):e2088. doi: 10.1371/journal.pntd.0002088. Epub 2013 Feb 28.

26.

New biomarkers for stage determination in Trypanosoma brucei rhodesiense sleeping sickness patients.

Tiberti N, Matovu E, Hainard A, Enyaru JC, Lejon V, Robin X, Turck N, Ngoyi DM, Krishna S, Bisser S, Courtioux B, Büscher P, Kristensson K, Ndung'u JM, Sanchez JC.

Clin Transl Med. 2013 Jan 7;2(1):1. doi: 10.1186/2001-1326-2-1.

27.

Cerebrospinal fluid neopterin as marker of the meningo-encephalitic stage of Trypanosoma brucei gambiense sleeping sickness.

Tiberti N, Hainard A, Lejon V, Courtioux B, Matovu E, Enyaru JC, Robin X, Turck N, Kristensson K, Ngoyi DM, Vatunga GM, Krishna S, Büscher P, Bisser S, Ndung'u JM, Sanchez JC.

PLoS One. 2012;7(7):e40909. doi: 10.1371/journal.pone.0040909. Epub 2012 Jul 18.

28.

Improved detection of Trypanosoma brucei by lysis of red blood cells, concentration and LED fluorescence microscopy.

Biéler S, Matovu E, Mitashi P, Ssewannyana E, Bi Shamamba SK, Bessell PR, Ndung'u JM.

Acta Trop. 2012 Feb;121(2):135-40. doi: 10.1016/j.actatropica.2011.10.016. Epub 2011 Nov 4.

PMID:
22079374
29.

Matrix metalloproteinase-9 and intercellular adhesion molecule 1 are powerful staging markers for human African trypanosomiasis.

Hainard A, Tiberti N, Robin X, Ngoyi DM, Matovu E, Enyaru JC, Müller M, Turck N, Ndung'u JM, Lejon V, Sanchez JC.

Trop Med Int Health. 2011 Jan;16(1):119-26. doi: 10.1111/j.1365-3156.2010.02642.x. Epub 2010 Oct 19.

30.

Discovery and verification of osteopontin and Beta-2-microglobulin as promising markers for staging human African trypanosomiasis.

Tiberti N, Hainard A, Lejon V, Robin X, Ngoyi DM, Turck N, Matovu E, Enyaru J, Ndung'u JM, Scherl A, Dayon L, Sanchez JC.

Mol Cell Proteomics. 2010 Dec;9(12):2783-95. doi: 10.1074/mcp.M110.001008. Epub 2010 Aug 19.

31.

"Piggy-backing" on diagnostic platforms brings hope to neglected diseases: the case of sleeping sickness.

Ndung'u JM, Bieler S, Roscigno G.

PLoS Negl Trop Dis. 2010 May 25;4(5):e715. doi: 10.1371/journal.pntd.0000715. No abstract available.

32.

Economic assessment of the performance of trypanotolerant cattle breeds in a pastoral production system in Kenya.

Maichomo MW, Kosura WO, Gathuma JM, Gitau GK, Ndung'u JM, Nyamwaro SO.

J S Afr Vet Assoc. 2009 Sep;80(3):157-62.

PMID:
20169748
33.

A combined CXCL10, CXCL8 and H-FABP panel for the staging of human African trypanosomiasis patients.

Hainard A, Tiberti N, Robin X, Lejon V, Ngoyi DM, Matovu E, Enyaru JC, Fouda C, Ndung'u JM, Lisacek F, Müller M, Turck N, Sanchez JC.

PLoS Negl Trop Dis. 2009 Jun 16;3(6):e459. doi: 10.1371/journal.pntd.0000459.

34.

Efficacy of the novel diamidine compound 2,5-Bis(4-amidinophenyl)- furan-bis-O-Methlylamidoxime (Pafuramidine, DB289) against Trypanosoma brucei rhodesiense infection in vervet monkeys after oral administration.

Mdachi RE, Thuita JK, Kagira JM, Ngotho JM, Murilla GA, Ndung'u JM, Tidwell RR, Hall JE, Brun R.

Antimicrob Agents Chemother. 2009 Mar;53(3):953-7. doi: 10.1128/AAC.00831-08. Epub 2008 Dec 8.

35.

Loop-mediated isothermal amplification (LAMP) method for rapid detection of Trypanosoma brucei rhodesiense.

Njiru ZK, Mikosza AS, Armstrong T, Enyaru JC, Ndung'u JM, Thompson AR.

PLoS Negl Trop Dis. 2008 Feb 6;2(1):e147. doi: 10.1371/journal.pntd.0000147.

36.

African trypanosomiasis: sensitive and rapid detection of the sub-genus Trypanozoon by loop-mediated isothermal amplification (LAMP) of parasite DNA.

Njiru ZK, Mikosza AS, Matovu E, Enyaru JC, Ouma JO, Kibona SN, Thompson RC, Ndung'u JM.

Int J Parasitol. 2008 Apr;38(5):589-99. Epub 2007 Oct 1.

37.

Isolation and propagation of Trypanosoma brucei gambiense from sleeping sickness patients in south Sudan.

Maina NW, Oberle M, Otieno C, Kunz C, Maeser P, Ndung'u JM, Brun R.

Trans R Soc Trop Med Hyg. 2007 Jun;101(6):540-6. Epub 2007 Feb 1.

PMID:
17275053
38.

Immunization of rabbits with Glossina pallidipes tsetse fly midgut proteins: effects on the fly and trypanosome transmission.

Kinyua JK, Nguu EK, Mulaa F, Ndung'u JM.

Vaccine. 2005 May 31;23(29):3824-8. Epub 2005 Apr 2.

PMID:
15893620
39.

Detection of Trypanosoma evansi in camels using PCR and CATT/T. evansi tests in Kenya.

Njiru ZK, Constantine CC, Ndung'u JM, Robertson I, Okaye S, Thompson RC, Reid SA.

Vet Parasitol. 2004 Oct 5;124(3-4):187-99.

PMID:
15381299
40.

Proinflammatory cytokine expression in the early phase of Trypanosoma brucei rhodesiense infection in vervet monkeys (Cercopithecus aethiops).

Maina N, Ngotho JM, Were T, Thuita JK, Mwangangi DM, Kagira JM, Ndung'u JM, Sternberg J.

Infect Immun. 2004 May;72(5):3063-5.

41.

Growth and mortality in sheep and goats under high tsetse challenge in Kenya.

Masiga DK, Okech G, Irungu P, Ouma J, Wekesa S, Ouma B, Guya SO, Ndung'u JM.

Trop Anim Health Prod. 2002 Nov;34(6):489-501.

PMID:
12537387
42.
43.

The effects of drug-sensitive and drug-resistant Trypanosoma congolense infections on the pharmacokinetics of homidium in Boran cattle.

Murilla GA, Peregrine AS, Ndung'u JM, Holmes PH, Eisler MC.

Acta Trop. 2002 Mar;81(3):185-95.

PMID:
11835895
44.

Unravelling the phylogenetic relationships of African trypanosomes of suids.

Gibson WC, Stevens JR, Mwendia CM, Ngotho JN, Ndung'u JM.

Parasitology. 2001 Jun;122(Pt 6):625-31.

PMID:
11444615
45.

Standardised tests in mice and cattle for the detection of drug resistance in tsetse-transmitted trypanosomes of African domestic cattle.

Eisler MC, Brandt J, Bauer B, Clausen PH, Delespaux V, Holmes PH, Ilemobade A, Machila N, Mbwambo H, McDermott J, Mehlitz D, Murilla G, Ndung'u JM, Peregrine AS, Sidibé I, Sinyangwe L, Geerts S.

Vet Parasitol. 2001 Jun 12;97(3):171-82.

PMID:
11390069
46.

Application of the Vettest 8008 system for the biochemical analysis of vervet monkey plasma.

Ngure RM, Gateri LM, Ngotho JM, Ndung'u JM.

Vet Rec. 2000 May 20;146(21):612-3.

PMID:
10870765
47.

Comparative sensitivity of dot-ELISA, PCR and dissection method for the detection of trypanosome infections in tsetse flies (Diptera: glossinidae).

Ouma JO, Masake RA, Masiga DK, Moloo SK, Njuguna JT, Ndung'u JM.

Acta Trop. 2000 May 31;75(3):315-21.

PMID:
10838215
48.

Financial analysis of animal trypanosomiasis control using cypermethrin pour-on in Kenya.

Kamau SW, Omukuba J, Kiragu J, Masika P, Ndung'u JM, Wachira P, Mehlitz D.

Prev Vet Med. 2000 Apr 28;44(3-4):231-46.

PMID:
10760405
49.

Development and evaluation of an enzyme-linked immunosorbent assay (ELISA) for the determination of the trypanocidal drug homidium in serum of treated cattle.

Murilla GA, Eisler MC, Peregrine AS, Ndung'u JM, Holmes PH.

J Vet Pharmacol Ther. 1999 Oct;22(5):301-7.

PMID:
10597533
50.

Some pharmacokinetic parameters of the trypanocidal drug homidium bromide in Friesian and Boran steers using an enzyme-linked immunosorbent assay (ELISA).

Murilla GA, Holmes PH, Peregrine AS, Eisler MC, Ndung'u JM.

J Vet Pharmacol Ther. 1999 Oct;22(5):295-300.

PMID:
10597532

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