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Items: 1 to 50 of 83

1.

Identification of inflammatory markers suitable for non-invasive, repeated measurement studies in biobehavioral research: A feasibility study.

Schenk HM, van Ockenburg SL, Nawijn MC, De Jonge P, Rosmalen JGM.

PLoS One. 2019 Sep 24;14(9):e0221993. doi: 10.1371/journal.pone.0221993. eCollection 2019.

2.

Nasal gene expression changes with inhaled corticosteroid treatment in asthma.

Boudewijn IM, Lan A, Faiz A, Cox CA, Brouwer S, Schokker S, Vroegop SJ, Nawijn MC, Woodruff PG, Christenson SA, Hagedoorn P, Frijlink HW, Choy DF, Brouwer U, Wisman M, Postma DS, Fingleton J, Beasley R, van den Berge M, Guryev V.

Allergy. 2019 Jun 22. doi: 10.1111/all.13952. [Epub ahead of print] No abstract available.

PMID:
31230369
3.

A cellular census of human lungs identifies novel cell states in health and in asthma.

Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA.

Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17.

PMID:
31209336
4.

Subcutaneous immunotherapy using modified Phl p5a-derived peptides efficiently alleviates allergic asthma in mice.

Hesse L, Feenstra R, Ambrosini M, de Jager WA, Petersen A, Vietor H, Unger WWJ, van Kooyk Y, Nawijn MC.

Allergy. 2019 May 23. doi: 10.1111/all.13918. [Epub ahead of print] No abstract available.

PMID:
31124150
5.

A review on the pathophysiology of asthma remission.

Carpaij OA, Burgess JK, Kerstjens HAM, Nawijn MC, van den Berge M.

Pharmacol Ther. 2019 Sep;201:8-24. doi: 10.1016/j.pharmthera.2019.05.002. Epub 2019 May 8. Review.

PMID:
31075356
6.

The Human Lung Cell Atlas: A High-Resolution Reference Map of the Human Lung in Health and Disease.

Schiller HB, Montoro DT, Simon LM, Rawlins EL, Meyer KB, Strunz M, Vieira Braga FA, Timens W, Koppelman GH, Budinger GRS, Burgess JK, Waghray A, van den Berge M, Theis FJ, Regev A, Kaminski N, Rajagopal J, Teichmann SA, Misharin AV, Nawijn MC.

Am J Respir Cell Mol Biol. 2019 Jul;61(1):31-41. doi: 10.1165/rcmb.2018-0416TR.

PMID:
30995076
7.

The Pediatric Cell Atlas: Defining the Growth Phase of Human Development at Single-Cell Resolution.

Taylor DM, Aronow BJ, Tan K, Bernt K, Salomonis N, Greene CS, Frolova A, Henrickson SE, Wells A, Pei L, Jaiswal JK, Whitsett J, Hamilton KE, MacParland SA, Kelsen J, Heuckeroth RO, Potter SS, Vella LA, Terry NA, Ghanem LR, Kennedy BC, Helbig I, Sullivan KE, Castelo-Soccio L, Kreigstein A, Herse F, Nawijn MC, Koppelman GH, Haendel M, Harris NL, Rokita JL, Zhang Y, Regev A, Rozenblatt-Rosen O, Rood JE, Tickle TL, Vento-Tormo R, Alimohamed S, Lek M, Mar JC, Loomes KM, Barrett DM, Uapinyoying P, Beggs AH, Agrawal PB, Chen YW, Muir AB, Garmire LX, Snapper SB, Nazarian J, Seeholzer SH, Fazelinia H, Singh LN, Faryabi RB, Raman P, Dawany N, Xie HM, Devkota B, Diskin SJ, Anderson SA, Rappaport EF, Peranteau W, Wikenheiser-Brokamp KA, Teichmann S, Wallace D, Peng T, Ding YY, Kim MS, Xing Y, Kong SW, Bönnemann CG, Mandl KD, White PS.

Dev Cell. 2019 Apr 8;49(1):10-29. doi: 10.1016/j.devcel.2019.03.001. Epub 2019 Mar 28. Review.

8.

Applying the CAMP trial asthma remission prediction model to the Dutch asthma remission studies.

Carpaij OA, Vonk JM, Nawijn MC, Kerstjens HAM, Koppelman GH, van den Berge M.

J Allergy Clin Immunol. 2019 May;143(5):1973-1975. doi: 10.1016/j.jaci.2019.01.040. Epub 2019 Mar 12. No abstract available.

PMID:
30876728
9.

Characterization of a lung epithelium specific E-cadherin knock-out model: Implications for obstructive lung pathology.

Post S, Heijink IH, Hesse L, Koo HK, Shaheen F, Fouadi M, Kuchibhotla VNS, Lambrecht BN, Van Oosterhout AJM, Hackett TL, Nawijn MC.

Sci Rep. 2018 Sep 5;8(1):13275. doi: 10.1038/s41598-018-31500-8.

10.

Cigarette smoke exposure decreases CFLAR expression in the bronchial epithelium, augmenting susceptibility for lung epithelial cell death and DAMP release.

Faiz A, Heijink IH, Vermeulen CJ, Guryev V, van den Berge M, Nawijn MC, Pouwels SD.

Sci Rep. 2018 Aug 20;8(1):12426. doi: 10.1038/s41598-018-30602-7.

11.

Serum periostin does not reflect type 2-driven inflammation in COPD.

Carpaij OA, Muntinghe FOW, Wagenaar MB, Habing JW, Timens W, Kerstjens HAM, Nawijn MC, Kunz LIZ, Hiemstra PS, Tew GW, Holweg CTJ, Brandsma CA, van den Berge M.

Respir Res. 2018 Jun 7;19(1):112. doi: 10.1186/s12931-018-0818-8.

12.

Subcutaneous immunotherapy suppresses Th2 inflammation and induces neutralizing antibodies, but sublingual immunotherapy suppresses airway hyperresponsiveness in grass pollen mouse models for allergic asthma.

Hesse L, Brouwer U, Petersen AH, Gras R, Bosman L, Brimnes J, Oude Elberink JNG, van Oosterhout AJM, Nawijn MC.

Clin Exp Allergy. 2018 Aug;48(8):1035-1049. doi: 10.1111/cea.13169. Epub 2018 Jun 8.

PMID:
29752757
13.

Genetic regulation of IL1RL1 methylation and IL1RL1-a protein levels in asthma.

Dijk FN, Xu C, Melén E, Carsin AE, Kumar A, Nolte IM, Gruzieva O, Pershagen G, Grotenboer NS, Savenije OEM, Antó JM, Lavi I, Dobaño C, Bousquet J, van der Vlies P, van der Valk RJP, de Jongste JC, Nawijn MC, Guerra S, Postma DS, Koppelman GH.

Eur Respir J. 2018 Mar 8;51(3). pii: 1701377. doi: 10.1183/13993003.01377-2017. Print 2018 Mar.

14.

DNA methylation in childhood asthma: an epigenome-wide meta-analysis.

Xu CJ, Söderhäll C, Bustamante M, Baïz N, Gruzieva O, Gehring U, Mason D, Chatzi L, Basterrechea M, Llop S, Torrent M, Forastiere F, Fantini MP, Carlsen KCL, Haahtela T, Morin A, Kerkhof M, Merid SK, van Rijkom B, Jankipersadsing SA, Bonder MJ, Ballereau S, Vermeulen CJ, Aguirre-Gamboa R, de Jongste JC, Smit HA, Kumar A, Pershagen G, Guerra S, Garcia-Aymerich J, Greco D, Reinius L, McEachan RRC, Azad R, Hovland V, Mowinckel P, Alenius H, Fyhrquist N, Lemonnier N, Pellet J, Auffray C; BIOS Consortium, van der Vlies P, van Diemen CC, Li Y, Wijmenga C, Netea MG, Moffatt MF, Cookson WOCM, Anto JM, Bousquet J, Laatikainen T, Laprise C, Carlsen KH, Gori D, Porta D, Iñiguez C, Bilbao JR, Kogevinas M, Wright J, Brunekreef B, Kere J, Nawijn MC, Annesi-Maesano I, Sunyer J, Melén E, Koppelman GH.

Lancet Respir Med. 2018 May;6(5):379-388. doi: 10.1016/S2213-2600(18)30052-3. Epub 2018 Feb 26.

15.

Subcutaneous immunotherapy with purified Der p1 and 2 suppresses type 2 immunity in a murine asthma model.

Hesse L, van Ieperen N, Habraken C, Petersen AH, Korn S, Smilda T, Goedewaagen B, Ruiters MH, van der Graaf AC, Nawijn MC.

Allergy. 2018 Apr;73(4):862-874. doi: 10.1111/all.13382. Epub 2018 Jan 31.

16.

The Human Cell Atlas.

Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell P, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, Enard W, Farmer A, Fugger L, Göttgens B, Hacohen N, Haniffa M, Hemberg M, Kim S, Klenerman P, Kriegstein A, Lein E, Linnarsson S, Lundberg E, Lundeberg J, Majumder P, Marioni JC, Merad M, Mhlanga M, Nawijn M, Netea M, Nolan G, Pe'er D, Phillipakis A, Ponting CP, Quake S, Reik W, Rozenblatt-Rosen O, Sanes J, Satija R, Schumacher TN, Shalek A, Shapiro E, Sharma P, Shin JW, Stegle O, Stratton M, Stubbington MJT, Theis FJ, Uhlen M, van Oudenaarden A, Wagner A, Watt F, Weissman J, Wold B, Xavier R, Yosef N; Human Cell Atlas Meeting Participants.

Elife. 2017 Dec 5;6. pii: e27041. doi: 10.7554/eLife.27041.

17.

Computational analysis of multimorbidity between asthma, eczema and rhinitis.

Aguilar D, Pinart M, Koppelman GH, Saeys Y, Nawijn MC, Postma DS, Akdis M, Auffray C, Ballereau S, Benet M, García-Aymerich J, González JR, Guerra S, Keil T, Kogevinas M, Lambrecht B, Lemonnier N, Melen E, Sunyer J, Valenta R, Valverde S, Wickman M, Bousquet J, Oliva B, Antó JM.

PLoS One. 2017 Jun 9;12(6):e0179125. doi: 10.1371/journal.pone.0179125. eCollection 2017.

18.

Genetic variance is associated with susceptibility for cigarette smoke-induced DAMP release in mice.

Pouwels SD, Faiz A, den Boef LE, Gras R, van den Berge M, Boezen HM, Korstanje R, Ten Hacken NHT, van Oosterhout AJM, Heijink IH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L559-L580. doi: 10.1152/ajplung.00466.2016. Epub 2017 Jun 8.

19.

Predictive value of serum sST2 in preschool wheezers for development of asthma with high FeNO.

Ketelaar ME, van de Kant KD, Dijk FN, Klaassen EM, Grotenboer NS, Nawijn MC, Dompeling E, Koppelman GH.

Allergy. 2017 Nov;72(11):1811-1815. doi: 10.1111/all.13193. Epub 2017 May 23.

PMID:
28440062
20.

Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes.

Anto JM, Bousquet J, Akdis M, Auffray C, Keil T, Momas I, Postma DS, Valenta R, Wickman M, Cambon-Thomsen A, Haahtela T, Lambrecht BN, Lodrup Carlsen KC, Koppelman GH, Sunyer J, Zuberbier T, Annesi-Maesano I, Arno A, Bindslev-Jensen C, De Carlo G, Forastiere F, Heinrich J, Kowalski ML, Maier D, Melén E, Smit HA, Standl M, Wright J, Asarnoj A, Benet M, Ballardini N, Garcia-Aymerich J, Gehring U, Guerra S, Hohmann C, Kull I, Lupinek C, Pinart M, Skrindo I, Westman M, Smagghe D, Akdis C, Andersson N, Bachert C, Ballereau S, Ballester F, Basagana X, Bedbrook A, Bergstrom A, von Berg A, Brunekreef B, Burte E, Carlsen KH, Chatzi L, Coquet JM, Curin M, Demoly P, Eller E, Fantini MP, von Hertzen L, Hovland V, Jacquemin B, Just J, Keller T, Kiss R, Kogevinas M, Koletzko S, Lau S, Lehmann I, Lemonnier N, Mäkelä M, Mestres J, Mowinckel P, Nadif R, Nawijn MC, Pellet J, Pin I, Porta D, Rancière F, Rial-Sebbag E, Saeys Y, Schuijs MJ, Siroux V, Tischer CG, Torrent M, Varraso R, Wenzel K, Xu CJ.

J Allergy Clin Immunol. 2017 Feb;139(2):388-399. doi: 10.1016/j.jaci.2016.12.940. Review.

PMID:
28183433
21.

Subcutaneous and Sublingual Immunotherapy in a Mouse Model of Allergic Asthma.

Hesse L, Nawijn MC.

Methods Mol Biol. 2017;1559:137-168. doi: 10.1007/978-1-4939-6786-5_11.

PMID:
28063043
22.

Susceptibility for cigarette smoke-induced DAMP release and DAMP-induced inflammation in COPD.

Pouwels SD, Hesse L, Faiz A, Lubbers J, Bodha PK, Ten Hacken NH, van Oosterhout AJ, Nawijn MC, Heijink IH.

Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L881-L892. doi: 10.1152/ajplung.00135.2016. Epub 2016 Sep 9.

23.

Protocadherin-1 Localization and Cell-Adhesion Function in Airway Epithelial Cells in Asthma.

Faura Tellez G, Willemse BW, Brouwer U, Nijboer-Brinksma S, Vandepoele K, Noordhoek JA, Heijink I, de Vries M, Smithers NP, Postma DS, Timens W, Wiffen L, van Roy F, Holloway JW, Lackie PM, Nawijn MC, Koppelman GH.

PLoS One. 2016 Oct 4;11(10):e0163967. doi: 10.1371/journal.pone.0163967. eCollection 2016.

24.

Increased neutrophil expression of pattern recognition receptors during COPD exacerbations.

Pouwels SD, van Geffen WH, Jonker MR, Kerstjens HA, Nawijn MC, Heijink IH.

Respirology. 2017 Feb;22(2):401-404. doi: 10.1111/resp.12912. Epub 2016 Sep 27.

PMID:
27679416
25.

Paving the way of systems biology and precision medicine in allergic diseases: the MeDALL success story: Mechanisms of the Development of ALLergy; EU FP7-CP-IP; Project No: 261357; 2010-2015.

Bousquet J, Anto JM, Akdis M, Auffray C, Keil T, Momas I, Postma DS, Valenta R, Wickman M, Cambon-Thomsen A, Haahtela T, Lambrecht BN, Lodrup Carlsen KC, Koppelman GH, Sunyer J, Zuberbier T, Annesi-Maesano I, Arno A, Bindslev-Jensen C, De Carlo G, Forastiere F, Heinrich J, Kowalski ML, Maier D, Melén E, Palkonen S, Smit HA, Standl M, Wright J, Asarnoj A, Benet M, Ballardini N, Garcia-Aymerich J, Gehring U, Guerra S, Hohman C, Kull I, Lupinek C, Pinart M, Skrindo I, Westman M, Smagghe D, Akdis C, Albang R, Anastasova V, Anderson N, Bachert C, Ballereau S, Ballester F, Basagana X, Bedbrook A, Bergstrom A, von Berg A, Brunekreef B, Burte E, Carlsen KH, Chatzi L, Coquet JM, Curin M, Demoly P, Eller E, Fantini MP, Gerhard B, Hammad H, von Hertzen L, Hovland V, Jacquemin B, Just J, Keller T, Kerkhof M, Kiss R, Kogevinas M, Koletzko S, Lau S, Lehmann I, Lemonnier N, McEachan R, Mäkelä M, Mestres J, Minina E, Mowinckel P, Nadif R, Nawijn M, Oddie S, Pellet J, Pin I, Porta D, Rancière F, Rial-Sebbag A, Saeys Y, Schuijs MJ, Siroux V, Tischer CG, Torrent M, Varraso R, De Vocht J, Wenger K, Wieser S, Xu C.

Allergy. 2016 Nov;71(11):1513-1525. doi: 10.1111/all.12880. Epub 2016 Aug 23. Review.

26.

Inhibition of Pim1 kinase, new therapeutic approach in virus-induced asthma exacerbations.

Vries Md, Bedke N, Smithers NP, Loxham M, Howarth PH, Nawijn MC, Davies DE.

Eur Respir J. 2016 Mar;47(3):783-91. doi: 10.1183/13993003.00171-2015. Epub 2016 Feb 11.

27.

The challenge of measuring IL-33 in serum using commercial ELISA: lessons from asthma.

Ketelaar ME, Nawijn MC, Shaw DE, Koppelman GH, Sayers I.

Clin Exp Allergy. 2016 Jun;46(6):884-7. doi: 10.1111/cea.12718.

PMID:
26850082
28.

Cigarette smoke-induced necroptosis and DAMP release trigger neutrophilic airway inflammation in mice.

Pouwels SD, Zijlstra GJ, van der Toorn M, Hesse L, Gras R, Ten Hacken NH, Krysko DV, Vandenabeele P, de Vries M, van Oosterhout AJ, Heijink IH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2016 Feb 15;310(4):L377-86. doi: 10.1152/ajplung.00174.2015. Epub 2015 Dec 30.

29.

Pim1 kinase activity preserves airway epithelial integrity upon house dust mite exposure.

de Vries M, Hesse L, Jonker MR, van den Berge M, van Oosterhout AJ, Heijink IH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2015 Dec 1;309(11):L1344-53. doi: 10.1152/ajplung.00043.2015. Epub 2015 Oct 9.

30.

Protocadherin-1 binds to SMAD3 and suppresses TGF-β1-induced gene transcription.

Faura Tellez G, Vandepoele K, Brouwer U, Koning H, Elderman RM, Hackett TL, Willemse BW, Holloway J, Van Roy F, Koppelman GH, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2015 Oct 1;309(7):L725-35. doi: 10.1152/ajplung.00346.2014. Epub 2015 Jul 24.

31.

Correction: Susceptibility to chronic mucus hypersecretion, a genome wide association study.

Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HS, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat M, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS; LifeLines Cohort Study.

PLoS One. 2015 May 29;10(5):e0129524. doi: 10.1371/journal.pone.0129524. eCollection 2015. No abstract available.

32.

Increased serum levels of LL37, HMGB1 and S100A9 during exacerbation in COPD patients.

Pouwels SD, Nawijn MC, Bathoorn E, Riezebos-Brilman A, van Oosterhout AJ, Kerstjens HA, Heijink IH.

Eur Respir J. 2015 May;45(5):1482-5. doi: 10.1183/09031936.00158414. No abstract available.

33.

Are allergic multimorbidities and IgE polysensitization associated with the persistence or re-occurrence of foetal type 2 signalling? The MeDALL hypothesis.

Bousquet J, Anto JM, Wickman M, Keil T, Valenta R, Haahtela T, Lodrup Carlsen K, van Hage M, Akdis C, Bachert C, Akdis M, Auffray C, Annesi-Maesano I, Bindslev-Jensen C, Cambon-Thomsen A, Carlsen KH, Chatzi L, Forastiere F, Garcia-Aymerich J, Gehrig U, Guerra S, Heinrich J, Koppelman GH, Kowalski ML, Lambrecht B, Lupinek C, Maier D, Melén E, Momas I, Palkonen S, Pinart M, Postma D, Siroux V, Smit HA, Sunyer J, Wright J, Zuberbier T, Arshad SH, Nadif R, Thijs C, Andersson N, Asarnoj A, Ballardini N, Ballereau S, Bedbrook A, Benet M, Bergstrom A, Brunekreef B, Burte E, Calderon M, De Carlo G, Demoly P, Eller E, Fantini MP, Hammad H, Hohman C, Just J, Kerkhof M, Kogevinas M, Kull I, Lau S, Lemonnier N, Mommers M, Nawijn M, Neubauer A, Oddie S, Pellet J, Pin I, Porta D, Saes Y, Skrindo I, Tischer CG, Torrent M, von Hertzen L.

Allergy. 2015 Sep;70(9):1062-78. doi: 10.1111/all.12637. Epub 2015 Jul 14. Review.

PMID:
25913421
34.

Inhibition of Pim1 kinase reduces viral replication in primary bronchial epithelial cells.

de Vries M, Smithers NP, Howarth PH, Nawijn MC, Davies DE.

Eur Respir J. 2015 Jun;45(6):1745-8. doi: 10.1183/09031936.00206514. Epub 2015 Mar 5. No abstract available.

35.

Genetic variation associates with susceptibility for cigarette smoke-induced neutrophilia in mice.

Pouwels SD, Heijink IH, Brouwer U, Gras R, den Boef LE, Boezen HM, Korstanje R, van Oosterhout AJ, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2015 Apr 1;308(7):L693-709. doi: 10.1152/ajplung.00118.2014. Epub 2015 Jan 30.

36.

Cigarette smoke-induced damage-associated molecular pattern release from necrotic neutrophils triggers proinflammatory mediator release.

Heijink IH, Pouwels SD, Leijendekker C, de Bruin HG, Zijlstra GJ, van der Vaart H, ten Hacken NH, van Oosterhout AJ, Nawijn MC, van der Toorn M.

Am J Respir Cell Mol Biol. 2015 May;52(5):554-62. doi: 10.1165/rcmb.2013-0505OC. Erratum in: Am J Respir Cell Mol Biol. 2016 Apr;54(4):597-9.

PMID:
25192219
37.

Basophil activation test in mastocytosis patients with and without wasp venom allergy.

Bidad K, Nawijn MC, van Oosterhout AJ, van der Heide S, Oude Elberink JN.

Cytometry B Clin Cytom. 2015 Jan;88(1):5. doi: 10.1002/cyto.b.21181. Epub 2014 Aug 28. No abstract available.

38.

Basophil activation test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy.

Bidad K, Nawijn M, van Oosterhout AJ, van der Heide S, Oude Elberink JN.

Cytometry B Clin Cytom. 2014 Aug 4. doi: 10.1002/cytob.21181. [Epub ahead of print] No abstract available.

39.

The role of the IL-33/IL-1RL1 axis in mast cell and basophil activation in allergic disorders.

Saluja R, Ketelaar ME, Hawro T, Church MK, Maurer M, Nawijn MC.

Mol Immunol. 2015 Jan;63(1):80-5. doi: 10.1016/j.molimm.2014.06.018. Epub 2014 Jul 10. Review.

PMID:
25017307
40.

Mouse protocadherin-1 gene expression is regulated by cigarette smoke exposure in vivo.

Koning H, van Oosterhout AJ, Brouwer U, den Boef LE, Gras R, Reinders-Luinge M, Brandsma CA, van der Toorn M, Hylkema MN, Willemse BW, Sayers I, Koppelman GH, Nawijn MC.

PLoS One. 2014 Jul 3;9(7):e98197. doi: 10.1371/journal.pone.0098197. eCollection 2014.

41.

Pim1 kinase protects airway epithelial cells from cigarette smoke-induced damage and airway inflammation.

de Vries M, Heijink IH, Gras R, den Boef LE, Reinders-Luinge M, Pouwels SD, Hylkema MN, van der Toorn M, Brouwer U, van Oosterhout AJ, Nawijn MC.

Am J Physiol Lung Cell Mol Physiol. 2014 Aug 1;307(3):L240-51. doi: 10.1152/ajplung.00156.2013. Epub 2014 May 9.

42.

Susceptibility to chronic mucus hypersecretion, a genome wide association study.

Dijkstra AE, Smolonska J, van den Berge M, Wijmenga C, Zanen P, Luinge MA, Platteel M, Lammers JW, Dahlback M, Tosh K, Hiemstra PS, Sterk PJ, Spira A, Vestbo J, Nordestgaard BG, Benn M, Nielsen SF, Dahl M, Verschuren WM, Picavet HS, Smit HA, Owsijewitsch M, Kauczor HU, de Koning HJ, Nizankowska-Mogilnicka E, Mejza F, Nastalek P, van Diemen CC, Cho MH, Silverman EK, Crapo JD, Beaty TH, Lomas DA, Bakke P, Gulsvik A, Bossé Y, Obeidat M, Loth DW, Lahousse L, Rivadeneira F, Uitterlinden AG, Hofman A, Stricker BH, Brusselle GG, van Duijn CM, Brouwer U, Koppelman GH, Vonk JM, Nawijn MC, Groen HJ, Timens W, Boezen HM, Postma DS; LifeLines Cohort study.

PLoS One. 2014 Apr 8;9(4):e91621. doi: 10.1371/journal.pone.0091621. eCollection 2014. Erratum in: PLoS One. 2015;10(5):e0129524. Obeidat, M A [corrected to Obeidat, Ma'en].

43.

Protease-activated receptor-2 activation contributes to house dust mite-induced IgE responses in mice.

Post S, Heijink IH, Petersen AH, de Bruin HG, van Oosterhout AJ, Nawijn MC.

PLoS One. 2014 Mar 20;9(3):e91206. doi: 10.1371/journal.pone.0091206. eCollection 2014.

44.

Airway epithelial barrier function regulates the pathogenesis of allergic asthma.

Heijink IH, Nawijn MC, Hackett TL.

Clin Exp Allergy. 2014;44(5):620-30. doi: 10.1111/cea.12296. Review.

PMID:
24612268
45.

Protocadherin-1: Epithelial barrier dysfunction in asthma and eczema.

Faura Tellez G, Nawijn MC, Koppelman GH.

Eur Respir J. 2014 Mar;43(3):671-4. doi: 10.1183/09031936.00179713. No abstract available.

46.

Basophil activation test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy on immunotherapy.

Bidad K, Nawijn MC, van Oosterhout AJ, van der Heide S, Elberink JN.

Cytometry B Clin Cytom. 2014 May;86(3):183-90. doi: 10.1002/cyto.b.21148. Epub 2014 Jan 29.

47.

Basophil Activation Test in the diagnosis and monitoring of mastocytosis patients with wasp venom allergy.

Bidad K, Nawijn MC, van Oosterhout AJ, van der Heide S, Elberink JN.

Cytometry B Clin Cytom. 2013 Dec 10. doi: 10.1002/cytob.21148. [Epub ahead of print]

48.

A specific DAMP profile identifies susceptibility to smoke-induced airway inflammation.

Pouwels SD, Heijink IH, van Oosterhout AJ, Nawijn MC.

Eur Respir J. 2014 Apr;43(4):1183-6. doi: 10.1183/09031936.00127813. Epub 2013 Dec 5. No abstract available.

49.

DAMPs activating innate and adaptive immune responses in COPD.

Pouwels SD, Heijink IH, ten Hacken NH, Vandenabeele P, Krysko DV, Nawijn MC, van Oosterhout AJ.

Mucosal Immunol. 2014 Mar;7(2):215-26. doi: 10.1038/mi.2013.77. Epub 2013 Oct 23. Review.

PMID:
24150257
50.

House dust mite-induced calcium signaling instigates epithelial barrier dysfunction and CCL20 production.

Post S, Nawijn MC, Jonker MR, Kliphuis N, van den Berge M, van Oosterhout AJ, Heijink IH.

Allergy. 2013 Sep;68(9):1117-25. doi: 10.1111/all.12202. Epub 2013 Aug 5.

PMID:
23915187

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