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Items: 18


Heterogeneity in non-epitope loop sequence and outer membrane protein complexes alters antibody binding to the major porin protein PorB in serogroup B Neisseria meningitidis.

Matthias KA, Strader MB, Nawar HF, Gao YS, Lee J, Patel DS, Im W, Bash MC.

Mol Microbiol. 2017 Sep;105(6):934-953. doi: 10.1111/mmi.13747. Epub 2017 Aug 1.


Interleukin-17-dependent CXCL13 mediates mucosal vaccine-induced immunity against tuberculosis.

Gopal R, Rangel-Moreno J, Slight S, Lin Y, Nawar HF, Fallert Junecko BA, Reinhart TA, Kolls J, Randall TD, Connell TD, Khader SA.

Mucosal Immunol. 2013 Sep;6(5):972-84. doi: 10.1038/mi.2012.135. Epub 2013 Jan 9.


Structure-activity correlations of variant forms of the B pentamer of Escherichia coli type II heat-labile enterotoxin LT-IIb with Toll-like receptor 2 binding.

Cody V, Pace J, Nawar HF, King-Lyons N, Liang S, Connell TD, Hajishengallis G.

Acta Crystallogr D Biol Crystallogr. 2012 Dec;68(Pt 12):1604-12. doi: 10.1107/S0907444912038917. Epub 2012 Nov 9.


Ganglioside-binding specificities of E. coli enterotoxin LT-IIc: Importance of long-chain fatty acyl ceramide.

Berenson CS, Nawar HF, Kruzel RL, Mandell LM, Connell TD.

Glycobiology. 2013 Jan;23(1):23-31. doi: 10.1093/glycob/cws123. Epub 2012 Aug 22.


LT-IIc, a new member of the type II heat-labile enterotoxin family, exhibits potent immunomodulatory properties that are different from those induced by LT-IIa or LT-IIb.

Nawar HF, Greene CJ, Lee CH, Mandell LM, Hajishengallis G, Connell TD.

Vaccine. 2011 Jan 17;29(4):721-7. doi: 10.1016/j.vaccine.2010.11.020. Epub 2010 Nov 21.


LT-IIc, a new member of the type II heat-labile enterotoxin family encoded by an Escherichia coli strain obtained from a nonmammalian host.

Nawar HF, King-Lyons ND, Hu JC, Pasek RC, Connell TD.

Infect Immun. 2010 Nov;78(11):4705-13. doi: 10.1128/IAI.00730-10. Epub 2010 Aug 16.


Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I).

Nawar HF, Berenson CS, Hajishengallis G, Takematsu H, Mandell L, Clare RL, Connell TD.

Clin Vaccine Immunol. 2010 Jun;17(6):969-78. doi: 10.1128/CVI.00076-10. Epub 2010 Apr 14.


Enhanced antigen uptake by dendritic cells induced by the B pentamer of the type II heat-labile enterotoxin LT-IIa requires engagement of TLR2.

Lee CH, Nawar HF, Mandell L, Liang S, Hajishengallis G, Connell TD.

Vaccine. 2010 May 7;28(21):3696-705. doi: 10.1016/j.vaccine.2010.03.016. Epub 2010 Mar 21.


Mammalian cell ganglioside-binding specificities of E. coli enterotoxins LT-IIb and variant LT-IIb(T13I).

Berenson CS, Nawar HF, Yohe HC, Castle SA, Ashline DJ, Reinhold VN, Hajishengallis G, Connell TD.

Glycobiology. 2010 Jan;20(1):41-54. doi: 10.1093/glycob/cwp141. Epub 2009 Sep 12.


In vivo and in vitro adjuvant activities of the B subunit of Type IIb heat-labile enterotoxin (LT-IIb-B5) from Escherichia coli.

Liang S, Hosur KB, Nawar HF, Russell MW, Connell TD, Hajishengallis G.

Vaccine. 2009 Jul 9;27(32):4302-8. doi: 10.1016/j.vaccine.2009.05.027. Epub 2009 May 29.


Ganglioside-linked terminal sialic acid moieties on murine macrophages function as attachment receptors for murine noroviruses.

Taube S, Perry JW, Yetming K, Patel SP, Auble H, Shu L, Nawar HF, Lee CH, Connell TD, Shayman JA, Wobus CE.

J Virol. 2009 May;83(9):4092-101. doi: 10.1128/JVI.02245-08. Epub 2009 Feb 25.


Mapping of a microbial protein domain involved in binding and activation of the TLR2/TLR1 heterodimer.

Liang S, Hosur KB, Lu S, Nawar HF, Weber BR, Tapping RI, Connell TD, Hajishengallis G.

J Immunol. 2009 Mar 1;182(5):2978-85. doi: 10.4049/jimmunol.0803737.


The A subunit of type IIb enterotoxin (LT-IIb) suppresses the proinflammatory potential of the B subunit and its ability to recruit and interact with TLR2.

Liang S, Wang M, Triantafilou K, Triantafilou M, Nawar HF, Russell MW, Connell TD, Hajishengallis G.

J Immunol. 2007 Apr 15;178(8):4811-9.


Ganglioside GD1a is an essential coreceptor for Toll-like receptor 2 signaling in response to the B subunit of type IIb enterotoxin.

Liang S, Wang M, Tapping RI, Stepensky V, Nawar HF, Triantafilou M, Triantafilou K, Connell TD, Hajishengallis G.

J Biol Chem. 2007 Mar 9;282(10):7532-42. Epub 2007 Jan 16.


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