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Items: 1 to 50 of 214

1.

AMPK activation, eEF2 inactivation, and reduced protein synthesis in the cerebral cortex of hibernating chipmunks.

Yamada S, Kamata T, Nawa H, Sekijima T, Takei N.

Sci Rep. 2019 Aug 15;9(1):11904. doi: 10.1038/s41598-019-48172-7.

2.

Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases.

Kobayashi Y, Iwakura Y, Sotoyama H, Kitayama E, Takei N, Someya T, Nawa H.

Transl Psychiatry. 2019 Aug 1;9(1):181. doi: 10.1038/s41398-019-0519-1.

3.

USP10 is a critical factor for Tau-positive stress granule formation in neuronal cells.

Piatnitskaia S, Takahashi M, Kitaura H, Katsuragi Y, Kakihana T, Zhang L, Kakita A, Iwakura Y, Nawa H, Miura T, Ikeuchi T, Hara T, Fujii M.

Sci Rep. 2019 Jul 22;9(1):10591. doi: 10.1038/s41598-019-47033-7.

4.

Neonatal exposure to an inflammatory cytokine, epidermal growth factor, results in the deficits of mismatch negativity in rats.

Jodo E, Inaba H, Narihara I, Sotoyama H, Kitayama E, Yabe H, Namba H, Eifuku S, Nawa H.

Sci Rep. 2019 May 16;9(1):7503. doi: 10.1038/s41598-019-43923-y.

5.

Pathological alterations of chondroitin sulfate moiety in postmortem hippocampus of patients with schizophrenia.

Yukawa T, Iwakura Y, Takei N, Saito M, Watanabe Y, Toyooka K, Igarashi M, Niizato K, Oshima K, Kunii Y, Yabe H, Matsumoto J, Wada A, Hino M, Iritani S, Niwa SI, Takeuchi R, Takahashi H, Kakita A, Someya T, Nawa H.

Psychiatry Res. 2018 Dec;270:940-946. doi: 10.1016/j.psychres.2018.10.062. Epub 2018 Oct 30.

PMID:
30551347
6.

USP10 Is a Driver of Ubiquitinated Protein Aggregation and Aggresome Formation to Inhibit Apoptosis.

Takahashi M, Kitaura H, Kakita A, Kakihana T, Katsuragi Y, Nameta M, Zhang L, Iwakura Y, Nawa H, Higuchi M, Komatsu M, Fujii M.

iScience. 2018 Nov 30;9:433-450. doi: 10.1016/j.isci.2018.11.006. Epub 2018 Nov 5.

7.

Human-specific features of spatial gene expression and regulation in eight brain regions.

Xu C, Li Q, Efimova O, He L, Tatsumoto S, Stepanova V, Oishi T, Udono T, Yamaguchi K, Shigenobu S, Kakita A, Nawa H, Khaitovich P, Go Y.

Genome Res. 2018 Aug;28(8):1097-1110. doi: 10.1101/gr.231357.117. Epub 2018 Jun 13.

8.

Effects of the -141C insertion/deletion polymorphism in the dopamine D2 receptor gene on the dopamine system in the striatum in patients with schizophrenia.

Matsumoto J, Nagaoka A, Kunii Y, Miura I, Hino M, Niwa SI, Nawa H, Takahashi H, Kakita A, Yabe H.

Psychiatry Res. 2018 Jun;264:116-118. doi: 10.1016/j.psychres.2018.03.029. Epub 2018 Mar 29.

PMID:
29627696
9.

Striatal hypodopamine phenotypes found in transgenic mice that overexpress glial cell line-derived neurotrophic factor.

Sotoyama H, Iwakura Y, Oda K, Sasaoka T, Takei N, Kakita A, Enomoto H, Nawa H.

Neurosci Lett. 2017 Jul 27;654:99-106. doi: 10.1016/j.neulet.2017.06.005. Epub 2017 Jun 21.

PMID:
28645787
10.

Epidermal growth factor signals attenuate phenotypic and functional development of neocortical GABA neurons.

Namba H, Nagano T, Jodo E, Eifuku S, Horie M, Takebayashi H, Iwakura Y, Sotoyama H, Takei N, Nawa H.

J Neurochem. 2017 Sep;142(6):886-900. doi: 10.1111/jnc.14097. Epub 2017 Jul 11.

11.

Glutamate-dependent ectodomain shedding of neuregulin-1 type II precursors in rat forebrain neurons.

Iwakura Y, Wang R, Inamura N, Araki K, Higashiyama S, Takei N, Nawa H.

PLoS One. 2017 Mar 28;12(3):e0174780. doi: 10.1371/journal.pone.0174780. eCollection 2017.

12.

Advanced glycation end products induce brain-derived neurotrophic factor release from human platelets through the Src-family kinase activation.

Furukawa K, Fuse I, Iwakura Y, Sotoyama H, Hanyu O, Nawa H, Sone H, Takei N.

Cardiovasc Diabetol. 2017 Feb 8;16(1):20. doi: 10.1186/s12933-017-0505-y.

13.
14.

Observation of maxillary incisive canal using dry skulls between Hellman's dental age IA and IIIC.

Naitoh M, Arikawa T, Nishiyama W, Gotoh K, Nawa H, Fukuta O, Ariji E.

Okajimas Folia Anat Jpn. 2015;92(2):37-42. doi: 10.2535/ofaj.92.37.

15.

Schisandrin B Ameliorates ICV-Infused Amyloid β Induced Oxidative Stress and Neuronal Dysfunction through Inhibiting RAGE/NF-κB/MAPK and Up-Regulating HSP/Beclin Expression.

Giridharan VV, Thandavarayan RA, Arumugam S, Mizuno M, Nawa H, Suzuki K, Ko KM, Krishnamurthy P, Watanabe K, Konishi T.

PLoS One. 2015 Nov 10;10(11):e0142483. doi: 10.1371/journal.pone.0142483. eCollection 2015.

16.

Pathological Implications of Oxidative Stress in Patients and Animal Models with Schizophrenia: The Role of Epidermal Growth Factor Receptor Signaling.

Nagano T, Mizuno M, Morita K, Nawa H.

Curr Top Behav Neurosci. 2016;29:429-446. doi: 10.1007/7854_2015_399.

PMID:
26475158
17.

Assessment of copy number variations in the brain genome of schizophrenia patients.

Sakai M, Watanabe Y, Someya T, Araki K, Shibuya M, Niizato K, Oshima K, Kunii Y, Yabe H, Matsumoto J, Wada A, Hino M, Hashimoto T, Hishimoto A, Kitamura N, Iritani S, Shirakawa O, Maeda K, Miyashita A, Niwa S, Takahashi H, Kakita A, Kuwano R, Nawa H.

Mol Cytogenet. 2015 Jul 1;8:46. doi: 10.1186/s13039-015-0144-5. eCollection 2015.

18.

Neurobehavioral Differences Between Mice Receiving Distinct Neuregulin Variants as Neonates; Impact on Sensitivity to MK-801.

Kato T, Abe Y, Hirokawa S, Iwakura Y, Mizuno M, Namba H, Nawa H.

Curr Mol Med. 2015;15(3):222-36.

19.

A possible link between BDNF and mTOR in control of food intake.

Takei N, Furukawa K, Hanyu O, Sone H, Nawa H.

Front Psychol. 2014 Sep 25;5:1093. doi: 10.3389/fpsyg.2014.01093. eCollection 2014. Review.

20.

Neuropathologic implication of peripheral neuregulin-1 and EGF signals in dopaminergic dysfunction and behavioral deficits relevant to schizophrenia: their target cells and time window.

Nawa H, Sotoyama H, Iwakura Y, Takei N, Namba H.

Biomed Res Int. 2014;2014:697935. doi: 10.1155/2014/697935. Epub 2014 May 13. Review.

21.

mTOR signaling and its roles in normal and abnormal brain development.

Takei N, Nawa H.

Front Mol Neurosci. 2014 Apr 23;7:28. doi: 10.3389/fnmol.2014.00028. eCollection 2014. Review.

22.

Reproducibility of maxillofacial landmark identification on three-dimensional cone-beam computed tomography images of patients with mandibular prognathism: Comparative study of a tentative method and traditional cephalometric analysis.

Fuyamada M, Shibata M, Nawa H, Yoshida K, Kise Y, Katsumata A, Ariji E, Goto S.

Angle Orthod. 2014 Nov;84(6):966-73. doi: 10.2319/111313-836.1. Epub 2014 Apr 21.

PMID:
24745629
23.

Elevated postmortem striatal t-DARPP expression in schizophrenia and associations with DRD2/ANKK1 polymorphism.

Kunii Y, Miura I, Matsumoto J, Hino M, Wada A, Niwa S, Nawa H, Sakai M, Someya T, Takahashi H, Kakita A, Yabe H.

Prog Neuropsychopharmacol Biol Psychiatry. 2014 Aug 4;53:123-8. doi: 10.1016/j.pnpbp.2014.03.014. Epub 2014 Apr 3.

PMID:
24704945
24.

Increased l1 retrotransposition in the neuronal genome in schizophrenia.

Bundo M, Toyoshima M, Okada Y, Akamatsu W, Ueda J, Nemoto-Miyauchi T, Sunaga F, Toritsuka M, Ikawa D, Kakita A, Kato M, Kasai K, Kishimoto T, Nawa H, Okano H, Yoshikawa T, Kato T, Iwamoto K.

Neuron. 2014 Jan 22;81(2):306-13. doi: 10.1016/j.neuron.2013.10.053. Epub 2014 Jan 2.

25.

AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons.

Ishizuka Y, Kakiya N, Witters LA, Oshiro N, Shirao T, Nawa H, Takei N.

J Neurochem. 2013 Oct;127(1):66-77. doi: 10.1111/jnc.12362. Epub 2013 Jul 29.

26.

Neurobehavioral deficits of epidermal growth factor-overexpressing transgenic mice: impact on dopamine metabolism.

Eda T, Mizuno M, Araki K, Iwakura Y, Namba H, Sotoyama H, Kakita A, Takahashi H, Satoh H, Chan SY, Nawa H.

Neurosci Lett. 2013 Jun 28;547:21-5. doi: 10.1016/j.neulet.2013.04.055. Epub 2013 May 10.

PMID:
23669645
27.

ErbB inhibitors ameliorate behavioral impairments of an animal model for schizophrenia: implication of their dopamine-modulatory actions.

Mizuno M, Sotoyama H, Namba H, Shibuya M, Eda T, Wang R, Okubo T, Nagata K, Iwakura Y, Nawa H.

Transl Psychiatry. 2013 Apr 30;3:e252. doi: 10.1038/tp.2013.29.

28.

ErbB2 dephosphorylation and anti-proliferative effects of neuregulin-1 in ErbB2-overexpressing cells; re-evaluation of their low-affinity interaction.

Wang R, Iwakura Y, Araki K, Keino-Masu K, Masu M, Wang XY, Takei N, Higashiyama S, Nawa H.

Sci Rep. 2013;3:1402. doi: 10.1038/srep01402.

29.

Exposure to the cytokine EGF leads to abnormal hyperactivity of pallidal GABA neurons: implications for schizophrenia and its modeling.

Sotoyama H, Namba H, Chiken S, Nambu A, Nawa H.

J Neurochem. 2013 Aug;126(4):518-28. doi: 10.1111/jnc.12223. Epub 2013 Mar 25.

30.
31.

[Usefulness of group work as a teaching strategy for long-term practical training in the 6-year pharmaceutical education].

Kubo K, Okazaki H, Ichikawa H, Nishihara S, Nawa H, Okazaki M, Kawasaki Y, Nakura H, Matsunaga H, Sendo T.

Yakugaku Zasshi. 2012;132(12):1467-76. Epub 2012 Sep 18. Japanese.

32.
33.

Anandamide induces endothelium-dependent vasoconstriction and CGRPergic nerve-mediated vasodilatation in the rat mesenteric vascular bed.

Tamaki C, Nawa H, Takatori S, Oda S, Sendo T, Zamami Y, Kawasaki H.

J Pharmacol Sci. 2012;118(4):496-505.

34.

Reproducibility of three-dimensional coordinate systems based on craniofacial landmarks: a tentative evaluation of four systems created on images obtained by cone-beam computed tomography with a large field of view.

Shibata M, Nawa H, Kise Y, Fuyamada M, Yoshida K, Katsumata A, Ariji E, Goto S.

Angle Orthod. 2012 Sep;82(5):776-84. doi: 10.2319/102511-662.1. Epub 2012 Feb 20.

PMID:
22348241
35.

[Vulnerability of dopamine circuit development to cytokines from the periphery: implication in schizophrenia].

Sotoyama H, Nawa H.

Nihon Shinkei Seishin Yakurigaku Zasshi. 2011 Nov;31(5-6):209-15. Review. Japanese.

PMID:
22256609
36.

Experimental schizophrenia models in rodents established with inflammatory agents and cytokines.

Nawa H, Yamada K.

Methods Mol Biol. 2012;829:445-51. doi: 10.1007/978-1-61779-458-2_28.

PMID:
22231831
37.

Association of SNPs linked to increased expression of SLC1A1 with schizophrenia.

Horiuchi Y, Iida S, Koga M, Ishiguro H, Iijima Y, Inada T, Watanabe Y, Someya T, Ujike H, Iwata N, Ozaki N, Kunugi H, Tochigi M, Itokawa M, Arai M, Niizato K, Iritani S, Kakita A, Takahashi H, Nawa H, Arinami T.

Am J Med Genet B Neuropsychiatr Genet. 2012 Jan;159B(1):30-7. doi: 10.1002/ajmg.b.31249. Epub 2011 Nov 16.

PMID:
22095641
38.

Pallidal hyperdopaminergic innervation underlying D2 receptor-dependent behavioral deficits in the schizophrenia animal model established by EGF.

Sotoyama H, Zheng Y, Iwakura Y, Mizuno M, Aizawa M, Shcherbakova K, Wang R, Namba H, Nawa H.

PLoS One. 2011;6(10):e25831. doi: 10.1371/journal.pone.0025831. Epub 2011 Oct 12.

39.

DPP6 as a candidate gene for neuroleptic-induced tardive dyskinesia.

Tanaka S, Syu A, Ishiguro H, Inada T, Horiuchi Y, Ishikawa M, Koga M, Noguchi E, Ozaki N, Someya T, Kakita A, Takahashi H, Nawa H, Arinami T.

Pharmacogenomics J. 2013 Feb;13(1):27-34. doi: 10.1038/tpj.2011.36. Epub 2011 Aug 9.

PMID:
21826085
40.

Reproducibility of landmark identification in the jaw and teeth on 3-dimensional cone-beam computed tomography images.

Fuyamada M, Nawa H, Shibata M, Yoshida K, Kise Y, Katsumata A, Ariji E, Goto S.

Angle Orthod. 2011 Sep;81(5):843-9. doi: 10.2319/010711-5.1. Epub 2011 May 13.

PMID:
21568647
41.

In vitro production of an active neurotrophic factor, neuregulin-1: qualitative comparison of different cell-free translation systems.

Wang R, Iwakura Y, Araki K, Sotoyama H, Takei N, Nawa H.

Neurosci Lett. 2011 Jun 22;497(2):90-3. doi: 10.1016/j.neulet.2011.04.036. Epub 2011 Apr 25.

PMID:
21536100
42.

Dopamine-dependent ectodomain shedding and release of epidermal growth factor in developing striatum: target-derived neurotrophic signaling (Part 2).

Iwakura Y, Wang R, Abe Y, Piao YS, Shishido Y, Higashiyama S, Takei N, Nawa H.

J Neurochem. 2011 Jul;118(1):57-68. doi: 10.1111/j.1471-4159.2011.07295.x. Epub 2011 May 25.

43.

Qualitative and quantitative re-evaluation of epidermal growth factor-ErbB1 action on developing midbrain dopaminergic neurons in vivo and in vitro: target-derived neurotrophic signaling (Part 1).

Iwakura Y, Zheng Y, Sibilia M, Abe Y, Piao YS, Yokomaku D, Wang R, Ishizuka Y, Takei N, Nawa H.

J Neurochem. 2011 Jul;118(1):45-56. doi: 10.1111/j.1471-4159.2011.07287.x. Epub 2011 May 19.

44.

Neuregulin-1 signals from the periphery regulate AMPA receptor sensitivity and expression in GABAergic interneurons in developing neocortex.

Abe Y, Namba H, Kato T, Iwakura Y, Nawa H.

J Neurosci. 2011 Apr 13;31(15):5699-709. doi: 10.1523/JNEUROSCI.3477-10.2011.

45.

mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain.

Aizawa M, Abe Y, Ito T, Handa H, Nawa H.

Neurosci Res. 2011 Apr;69(4):343-7. doi: 10.1016/j.neures.2010.12.019. Epub 2011 Jan 15.

PMID:
21241746
46.

Phenotypic characterization of transgenic mice overexpressing neuregulin-1.

Kato T, Kasai A, Mizuno M, Fengyi L, Shintani N, Maeda S, Yokoyama M, Ozaki M, Nawa H.

PLoS One. 2010 Dec 9;5(12):e14185. doi: 10.1371/journal.pone.0014185.

47.

Antipsychotic potential of quinazoline ErbB1 inhibitors in a schizophrenia model established with neonatal hippocampal lesioning.

Mizuno M, Iwakura Y, Shibuya M, Zheng Y, Eda T, Kato T, Takasu Y, Nawa H.

J Pharmacol Sci. 2010;114(3):320-31. Epub 2010 Oct 14.

48.

The anthraquinone derivative emodin attenuates methamphetamine-induced hyperlocomotion and startle response in rats.

Mizuno M, Kawamura H, Ishizuka Y, Sotoyama H, Nawa H.

Pharmacol Biochem Behav. 2010 Dec;97(2):392-8. doi: 10.1016/j.pbb.2010.09.009. Epub 2010 Sep 21.

PMID:
20863847
49.

Cytokine hypothesis of schizophrenia pathogenesis: evidence from human studies and animal models.

Watanabe Y, Someya T, Nawa H.

Psychiatry Clin Neurosci. 2010 Jun;64(3):217-30. doi: 10.1111/j.1440-1819.2010.02094.x. Review.

50.

Activation of mammalian target of rapamycin signaling in spatial learning.

Qi S, Mizuno M, Yonezawa K, Nawa H, Takei N.

Neurosci Res. 2010 Oct;68(2):88-93. doi: 10.1016/j.neures.2010.06.008. Epub 2010 Jun 25.

PMID:
20599569

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