Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 45

1.

Shared Platform for Antibiotic Research and Knowledge: A Collaborative Tool to SPARK Antibiotic Discovery.

Thomas J, Navre M, Rubio A, Coukell A.

ACS Infect Dis. 2018 Nov 9;4(11):1536-1539. doi: 10.1021/acsinfecdis.8b00193. Epub 2018 Sep 21.

PMID:
30240184
2.

Design of Gut-Restricted Thiazolidine Agonists of G Protein-Coupled Bile Acid Receptor 1 (GPBAR1, TGR5).

Chen T, Reich NW, Bell N, Finn PD, Rodriguez D, Kohler J, Kozuka K, He L, Spencer AG, Charmot D, Navre M, Carreras CW, Koo-McCoy S, Tabora J, Caldwell JS, Jacobs JW, Lewis JG.

J Med Chem. 2018 Sep 13;61(17):7589-7613. doi: 10.1021/acs.jmedchem.8b00308. Epub 2018 Aug 24.

PMID:
30141927
3.

Gastrointestinal Inhibition of Sodium-Hydrogen Exchanger 3 Reduces Phosphorus Absorption and Protects against Vascular Calcification in CKD.

Labonté ED, Carreras CW, Leadbetter MR, Kozuka K, Kohler J, Koo-McCoy S, He L, Dy E, Black D, Zhong Z, Langsetmo I, Spencer AG, Bell N, Deshpande D, Navre M, Lewis JG, Jacobs JW, Charmot D.

J Am Soc Nephrol. 2015 May;26(5):1138-49. doi: 10.1681/ASN.2014030317. Epub 2014 Nov 17.

4.

Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibits Na+ uptake in humans.

Spencer AG, Labonte ED, Rosenbaum DP, Plato CF, Carreras CW, Leadbetter MR, Kozuka K, Kohler J, Koo-McCoy S, He L, Bell N, Tabora J, Joly KM, Navre M, Jacobs JW, Charmot D.

Sci Transl Med. 2014 Mar 12;6(227):227ra36. doi: 10.1126/scitranslmed.3007790.

5.

Design and synthesis of pyrimidinone and pyrimidinedione inhibitors of dipeptidyl peptidase IV.

Zhang Z, Wallace MB, Feng J, Stafford JA, Skene RJ, Shi L, Lee B, Aertgeerts K, Jennings A, Xu R, Kassel DB, Kaldor SW, Navre M, Webb DR, Gwaltney SL.

J Med Chem. 2011 Jan 27;54(2):510-24. doi: 10.1021/jm101016w. Epub 2010 Dec 27.

PMID:
21186796
6.

Exploration of the HDAC2 foot pocket: Synthesis and SAR of substituted N-(2-aminophenyl)benzamides.

Bressi JC, Jennings AJ, Skene R, Wu Y, Melkus R, De Jong R, O'Connell S, Grimshaw CE, Navre M, Gangloff AR.

Bioorg Med Chem Lett. 2010 May 15;20(10):3142-5. doi: 10.1016/j.bmcl.2010.03.091. Epub 2010 Mar 30.

PMID:
20392638
7.

Benzimidazole and imidazole inhibitors of histone deacetylases: Synthesis and biological activity.

Bressi JC, de Jong R, Wu Y, Jennings AJ, Brown JW, O'Connell S, Tari LW, Skene RJ, Vu P, Navre M, Cao X, Gangloff AR.

Bioorg Med Chem Lett. 2010 May 15;20(10):3138-41. doi: 10.1016/j.bmcl.2010.03.092. Epub 2010 Mar 30.

PMID:
20392637
8.

Discovery of alogliptin: a potent, selective, bioavailable, and efficacious inhibitor of dipeptidyl peptidase IV.

Feng J, Zhang Z, Wallace MB, Stafford JA, Kaldor SW, Kassel DB, Navre M, Shi L, Skene RJ, Asakawa T, Takeuchi K, Xu R, Webb DR, Gwaltney SL 2nd.

J Med Chem. 2007 May 17;50(10):2297-300. Epub 2007 Apr 19. Erratum in: J Med Chem. 2008 Jul 24;51(14):4357.

PMID:
17441705
9.
10.

Characterization of the two catalytic domains in histone deacetylase 6.

Zou H, Wu Y, Navre M, Sang BC.

Biochem Biophys Res Commun. 2006 Mar 3;341(1):45-50. Epub 2006 Jan 6.

PMID:
16412385
11.

Application of combinatorial chemistry to antimicrobial drug discovery.

Navre M.

Expert Opin Investig Drugs. 1998 Aug;7(8):1257-71.

PMID:
15992029
12.

Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases.

Somoza JR, Skene RJ, Katz BA, Mol C, Ho JD, Jennings AJ, Luong C, Arvai A, Buggy JJ, Chi E, Tang J, Sang BC, Verner E, Wynands R, Leahy EM, Dougan DR, Snell G, Navre M, Knuth MW, Swanson RV, McRee DE, Tari LW.

Structure. 2004 Jul;12(7):1325-34.

13.

Global transcriptional response of Bacillus subtilis to heat shock.

Helmann JD, Wu MF, Kobel PA, Gamo FJ, Wilson M, Morshedi MM, Navre M, Paddon C.

J Bacteriol. 2001 Dec;183(24):7318-28.

14.

The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells.

Simian M, Hirai Y, Navre M, Werb Z, Lochter A, Bissell MJ.

Development. 2001 Aug;128(16):3117-31.

15.

Reaction kinetics of protease with substrate phage. Kinetic model developed using stromelysin.

Sharkov NA, Davis RM, Reidhaar-Olson JF, Navre M, Cai D.

J Biol Chem. 2001 Apr 6;276(14):10788-93. Epub 2001 Jan 10.

16.

Expression of human gelatinase B in Pichia pastoris.

Roy N, Padmanabhan S, Smith M, Shi L, Navre M, Das G.

Protein Expr Purif. 1999 Jul;16(2):324-30.

PMID:
10419828
17.

Identification of highly selective inhibitors of collagenase-1 from combinatorial libraries of diketopiperazines.

Szardenings AK, Antonenko V, Campbell DA, DeFrancisco N, Ida S, Shi L, Sharkov N, Tien D, Wang Y, Navre M.

J Med Chem. 1999 Apr 22;42(8):1348-57.

PMID:
10212120
18.
19.

The asymmetric synthesis and in vitro characterization of succinyl mercaptoalcohol and mercaptoketone inhibitors of matrix metalloproteinases.

Levin JI, DiJoseph JF, Killar LM, Sharr MA, Skotnicki JS, Patel DV, Xiao XY, Shi L, Navre M, Campbell DA.

Bioorg Med Chem Lett. 1998 May 19;8(10):1163-8.

PMID:
9871728
20.

Malonyl alpha-mercaptoketones and alpha-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors.

Campbell DA, Xiao XY, Harris D, Ida S, Mortezaei R, Ngu K, Shi L, Tien D, Wang Y, Navre M, Patel DV, Sharr MA, DiJoseph JF, Killar LM, Leone CL, Levin JI, Skotnicki JS.

Bioorg Med Chem Lett. 1998 May 19;8(10):1157-62.

PMID:
9871727
21.

Substrate specificity of prostate-specific antigen (PSA).

Coombs GS, Bergstrom RC, Pellequer JL, Baker SI, Navre M, Smith MM, Tainer JA, Madison EL, Corey DR.

Chem Biol. 1998 Sep;5(9):475-88.

22.

Rational design and combinatorial evaluation of enzyme inhibitor scaffolds: identification of novel inhibitors of matrix metalloproteinases.

Szardenings AK, Harris D, Lam S, Shi L, Tien D, Wang Y, Patel DV, Navre M, Campbell DA.

J Med Chem. 1998 Jun 18;41(13):2194-200.

PMID:
9632351
23.

Screening for novel antimicrobials from encoded combinatorial libraries by using a two-dimensional agar format.

Silen JL, Lu AT, Solas DW, Gore MA, MacLean D, Shah NH, Coffin JM, Bhinderwala NS, Wang Y, Tsutsui KT, Look GC, Campbell DA, Hale RL, Navre M, DeLuca-Flaherty CR.

Antimicrob Agents Chemother. 1998 Jun;42(6):1447-53.

24.
26.

Origins of the specificity of tissue-type plasminogen activator.

Ding L, Coombs GS, Strandberg L, Navre M, Corey DR, Madison EL.

Proc Natl Acad Sci U S A. 1995 Aug 15;92(17):7627-31.

28.

Modulation of matrilysin levels in colon carcinoma cell lines affects tumorigenicity in vivo.

Witty JP, McDonnell S, Newell KJ, Cannon P, Navre M, Tressler RJ, Matrisian LM.

Cancer Res. 1994 Sep 1;54(17):4805-12.

29.

Comparative sequence specificities of human 72- and 92-kDa gelatinases (type IV collagenases) and PUMP (matrilysin).

Netzel-Arnett S, Sang QX, Moore WG, Navre M, Birkedal-Hansen H, Van Wart HE.

Biochemistry. 1993 Jun 29;32(25):6427-32.

PMID:
8390857
30.

Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice.

Powell WC, Knox JD, Navre M, Grogan TM, Kittelson J, Nagle RB, Bowden GT.

Cancer Res. 1993 Jan 15;53(2):417-22.

31.

Expression and localization of matrilysin, a matrix metalloproteinase, in human endometrium during the reproductive cycle.

Rodgers WH, Osteen KG, Matrisian LM, Navre M, Giudice LC, Gorstein F.

Am J Obstet Gynecol. 1993 Jan;168(1 Pt 1):253-60.

PMID:
8420336
32.

Growth and developmental regulation of wnt-2 (irp) gene in mesenchymal cells of fetal lung.

Levay-Young BK, Navre M.

Am J Physiol. 1992 Jun;262(6 Pt 1):L672-83.

PMID:
1377452
33.
34.

The role of the matrix metalloproteinase stromelysin in the progression of squamous cell carcinomas.

Matrisian LM, McDonnell S, Miller DB, Navre M, Seftor EA, Hendrix MJ.

Am J Med Sci. 1991 Sep;302(3):157-62. Review.

PMID:
1928226
35.

Glucocorticoid induction of the adipocyte clone 5 gene requires high cell density.

Williams PM, Navre M, Ringold GM.

Mol Endocrinol. 1991 May;5(5):615-8.

PMID:
1712909
36.

Mutational analysis of the transin (rat stromelysin) autoinhibitor region demonstrates a role for residues surrounding the "cysteine switch".

Park AJ, Matrisian LM, Kells AF, Pearson R, Yuan ZY, Navre M.

J Biol Chem. 1991 Jan 25;266(3):1584-90.

37.

Expression and localization of the matrix metalloproteinase pump-1 (MMP-7) in human gastric and colon carcinomas.

McDonnell S, Navre M, Coffey RJ Jr, Matrisian LM.

Mol Carcinog. 1991;4(6):527-33.

PMID:
1793490
39.

Induction of adenosine 3',5'-monophosphate-dependent protein kinase subunits during adipogenesis in vitro.

Kurten RC, Navre M, Gaddy-Kurten D, Semenkovich CF, Ringold GM, Chan L, Richards JS.

Endocrinology. 1988 Nov;123(5):2408-18.

PMID:
2844511
41.

Hormonal control of adipocyte differentiation and adipocyte gene expression.

Ringold GM, Chapman AB, Knight DM, Navre M, Torti FM.

Recent Prog Horm Res. 1988;44:115-40. Review. No abstract available.

PMID:
3064205
42.

Requirements for triggering of adipocyte differentiation by glucocorticoids and indomethacin.

Knight DM, Chapman AB, Navre M, Drinkwater L, Bruno JJ, Ringold GM.

Mol Endocrinol. 1987 Jan;1(1):36-43.

PMID:
3454870
43.

Location of amino acid alterations in mutants of aspartate transcarbamoylase: Structural aspects of interallelic complementation.

Schachman HK, Pauza CD, Navre M, Karels MJ, Wu L, Yang YR.

Proc Natl Acad Sci U S A. 1984 Jan;81(1):115-9.

44.
45.

Genes encoding Escherichia coli aspartate transcarbamoylase: the pyrB-pyrI operon.

Pauza CD, Karels MJ, Navre M, Schachman HK.

Proc Natl Acad Sci U S A. 1982 Jul;79(13):4020-4.

Supplemental Content

Support Center