Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 38

1.

A call to arms: Unifying the fight against resistance.

Kaushansky A, Hedstrom L, Goldman A, Singh J, Yang PL, Rathod PK, Cynamon M, Wodarz D, Mahadevan D, Tomaras A, Navia MA, Schiffer CA.

Sci Signal. 2018 Oct 23;11(553). pii: eaav0442. doi: 10.1126/scisignal.aav0442.

PMID:
30352947
2.

Synthesis of Aspartame by Thermolysin: An X-ray Structural Study.

Birrane G, Bhyravbhatla B, Navia MA.

ACS Med Chem Lett. 2014 Apr 10;5(6):706-10. doi: 10.1021/ml500101z. eCollection 2014 Jun 12.

3.

Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity.

Longo KA, Govek EK, Nolan A, McDonagh T, Charoenthongtrakul S, Giuliana DJ, Morgan K, Hixon J, Zhou C, Kelder B, Kopchick JJ, Saunders JO, Navia MA, Curtis R, DiStefano PS, Geddes BJ.

J Pharmacol Exp Ther. 2011 Oct;339(1):115-24. doi: 10.1124/jpet.111.183764. Epub 2011 Jul 20. Erratum in: J Pharmacol Exp Ther. 2012 Mar;340(3):810.

PMID:
21775475
4.

Discovery of indoles as potent and selective inhibitors of the deacetylase SIRT1.

Napper AD, Hixon J, McDonagh T, Keavey K, Pons JF, Barker J, Yau WT, Amouzegh P, Flegg A, Hamelin E, Thomas RJ, Kates M, Jones S, Navia MA, Saunders JO, DiStefano PS, Curtis R.

J Med Chem. 2005 Dec 15;48(25):8045-54. Erratum in: J Med Chem. 2007 Mar 8;50(5):1086.

PMID:
16335928
5.

Protein Crystals as Novel Catalytic Materials.

Margolin AL, Navia MA.

Angew Chem Int Ed Engl. 2001 Jun 18;40(12):2204-2222.

PMID:
11433482
6.

Evaluation of insulin resistance in two kinds of South American camelids: llamas and alpacas.

Araya AV, Atwater I, Navia MA, Jeffs S.

Comp Med. 2000 Oct;50(5):490-4.

PMID:
11099130
7.

A chicken in every pot, thanks to sulfonamide drugs.

Navia MA.

Science. 2000 Jun 23;288(5474):2132-3. No abstract available.

PMID:
10896586
8.

Rational design of new immunosuppressive drugs.

Navia MA.

Transplant Proc. 1999 Feb-Mar;31(1-2):1097-8. Review. No abstract available.

PMID:
10083489
9.

Protein-drug complexes important for immunoregulation and organ transplantation.

Navia MA.

Curr Opin Struct Biol. 1996 Dec;6(6):838-47. Review.

PMID:
8994885
11.

The Devi case and more.

Navia MA.

Science. 1995 Aug 25;269(5227):1035. No abstract available.

PMID:
7662030
12.

X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.

Griffith JP, Kim JL, Kim EE, Sintchak MD, Thomson JA, Fitzgibbon MJ, Fleming MA, Caron PR, Hsiao K, Navia MA.

Cell. 1995 Aug 11;82(3):507-22.

13.

Design, synthesis and structure of non-macrocyclic inhibitors of FKBP12, the major binding protein for the immunosuppressant FK506.

Armistead DM, Badia MC, Deininger DD, Duffy JP, Saunders JO, Tung RD, Thomson JA, DeCenzo MT, Futer O, Livingston DJ, Murcko MA, Yamashita MM, Navia MA.

Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):522-8.

PMID:
15299839
14.

Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin.

Wilson KP, Yamashita MM, Sintchak MD, Rotstein SH, Murcko MA, Boger J, Thomson JA, Fitzgibbon MJ, Black JR, Navia MA.

Acta Crystallogr D Biol Crystallogr. 1995 Jul 1;51(Pt 4):511-21.

PMID:
15299838
15.

Structure and mechanism of interleukin-1 beta converting enzyme.

Wilson KP, Black JA, Thomson JA, Kim EE, Griffith JP, Navia MA, Murcko MA, Chambers SP, Aldape RA, Raybuck SA, et al.

Nature. 1994 Jul 28;370(6487):270-5.

PMID:
8035875
16.

Enthalpy of hydrogen bond formation in a protein-ligand binding reaction.

Connelly PR, Aldape RA, Bruzzese FJ, Chambers SP, Fitzgibbon MJ, Fleming MA, Itoh S, Livingston DJ, Navia MA, Thomson JA, et al.

Proc Natl Acad Sci U S A. 1994 Mar 1;91(5):1964-8.

17.

Preliminary analysis of multiple crystal forms of the bovine cyclophilin-cyclosporin A complex.

Itoh S, Fitzgibbon MJ, Black JR, Navia MA.

J Mol Biol. 1994 Jan 21;235(3):1136-40.

PMID:
8289312
18.

Structure-based drug design: applications in immunopharmacology and immunosuppression.

Navia MA, Peattie DA.

Immunol Today. 1993 Jun;14(6):296-302. Review. Erratum in: Immunol Today. 2008 Apr;29(4):149.

PMID:
8397770
19.

Structure-based drug design: applications in immunopharmacology and immunosuppression.

Navia MA, Peattie DA.

Trends Pharmacol Sci. 1993 May;14(5):189-95. Review.

PMID:
8212315
20.

Inhibition of human leukocyte elastase. 2. Inhibition by substituted cephalosporin esters and amides.

Finke PE, Ashe BM, Knight WB, Maycock AL, Navia MA, Shah SK, Thompson KR, Underwood DJ, Weston H, Zimmerman M, et al.

J Med Chem. 1990 Sep;33(9):2522-8.

PMID:
2391692
21.
22.

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1.

Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP.

Nature. 1989 Feb 16;337(6208):615-20.

PMID:
2645523
23.

Crystallization of the aspartylprotease from the human immunodeficiency virus, HIV-1.

McKeever BM, Navia MA, Fitzgerald PM, Springer JP, Leu CT, Heimbach JC, Herbert WK, Sigal IS, Darke PL.

J Biol Chem. 1989 Feb 5;264(4):1919-21.

24.

Structure of human neutrophil elastase in complex with a peptide chloromethyl ketone inhibitor at 1.84-A resolution.

Navia MA, McKeever BM, Springer JP, Lin TY, Williams HR, Fluder EM, Dorn CP, Hoogsteen K.

Proc Natl Acad Sci U S A. 1989 Jan;86(1):7-11.

25.

Purification, sequence, and model structure of charybdotoxin, a potent selective inhibitor of calcium-activated potassium channels.

Gimenez-Gallego G, Navia MA, Reuben JP, Katz GM, Kaczorowski GJ, Garcia ML.

Proc Natl Acad Sci U S A. 1988 May;85(10):3329-33.

26.

Crystallization of human neutrophil elastase.

Williams HR, Lin TY, Navia MA, Springer JP, McKeever BM, Hoogsteen K, Dorn CP Jr.

J Biol Chem. 1987 Dec 15;262(35):17178-81.

27.

Crystallographic study of a beta-lactam inhibitor complex with elastase at 1.84 A resolution.

Navia MA, Springer JP, Lin TY, Williams HR, Firestone RA, Pisano JM, Doherty JB, Finke PE, Hoogsteen K.

Nature. 1987 May 7-13;327(6117):79-82.

PMID:
3646481
28.

Pig pancreatic anhydro-elastase. Role of the serine-195 hydroxy group in the binding of inhibitors and substrate.

Williams HR, Lin TY, Navia MA, Springer JP, Hoogsteen K.

Biochem J. 1987 Feb 15;242(1):267-73.

29.

The galactan-binding immunoglobulin Fab J539: an X-ray diffraction study at 2.6-A resolution.

Suh SW, Bhat TN, Navia MA, Cohen GH, Rao DN, Rudikoff S, Davies DR.

Proteins. 1986 Sep;1(1):74-80.

PMID:
3449853
30.

Preliminary X-ray crystallographic data on mouse submaxillary gland renin and renin-inhibitor complexes.

Navia MA, Springer JP, Poe M, Boger J, Hoogsteen K.

J Biol Chem. 1984 Oct 25;259(20):12714-7.

31.
32.

Improving the quality of protein crystals through purification by isoelectric focusing.

Bott RR, Navia MA, Smith JL.

J Biol Chem. 1982 Sep 10;257(17):9883-6.

33.

Expression of biological effector functions by immunoglobulin G molecules lacking the hinge region.

Klein M, Haeffner-Cavaillon N, Isenman DE, Rivat C, Navia MA, Davies DR, Dorrington KJ.

Proc Natl Acad Sci U S A. 1981 Jan;78(1):524-8.

34.
35.

Crystal structure of galactan-binding mouse immunoglobulin J539 Fab at 4.5-A resolution.

Navia MA, Segal DM, Padlan EA, Davies DR, Rao N, Rudikoff S, Potter M.

Proc Natl Acad Sci U S A. 1979 Aug;76(8):4071-4.

36.

Three-dimensional structure of an intact human immunoglobulin.

Silverton EW, Navia MA, Davies DR.

Proc Natl Acad Sci U S A. 1977 Nov;74(11):5140-4.

37.

An ordered single-stranded structure for polyadenylic acid in denaturing solvents. An X-ray fiber diffraction and model building study.

Zimmerman SB, Davies DR, Navia MA.

J Mol Biol. 1977 Oct 25;116(2):317-30. No abstract available.

PMID:
599560
38.

An isomorphous heavy-atom derivative of crystaline formylmethionine transfer RNA.

Schevitz RW, Navia MA, Bantz DA, Cornick G, Rosa JJ, Rosa MD, Sigler PB.

Science. 1972 Aug 4;177(4047):429-31.

PMID:
5043142

Supplemental Content

Loading ...
Support Center