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Items: 12


Dendrimer-based postnatal therapy for neuroinflammation and cerebral palsy in a rabbit model.

Kannan S, Dai H, Navath RS, Balakrishnan B, Jyoti A, Janisse J, Romero R, Kannan RM.

Sci Transl Med. 2012 Apr 18;4(130):130ra46. doi: 10.1126/scitranslmed.3003162.


Injectable PAMAM dendrimer-PEG hydrogels for the treatment of genital infections: formulation and in vitro and in vivo evaluation.

Navath RS, Menjoge AR, Dai H, Romero R, Kannan S, Kannan RM.

Mol Pharm. 2011 Aug 1;8(4):1209-23. doi: 10.1021/mp200027z. Epub 2011 Jun 20.


Transfer of PAMAM dendrimers across human placenta: prospects of its use as drug carrier during pregnancy.

Menjoge AR, Rinderknecht AL, Navath RS, Faridnia M, Kim CJ, Romero R, Miller RK, Kannan RM.

J Control Release. 2011 Mar 30;150(3):326-38. doi: 10.1016/j.jconrel.2010.11.023. Epub 2010 Dec 1.


Intrinsic targeting of inflammatory cells in the brain by polyamidoamine dendrimers upon subarachnoid administration.

Dai H, Navath RS, Balakrishnan B, Guru BR, Mishra MK, Romero R, Kannan RM, Kannan S.

Nanomedicine (Lond). 2010 Nov;5(9):1317-29. doi: 10.2217/nnm.10.89.


Inhibition of bacterial growth and intramniotic infection in a guinea pig model of chorioamnionitis using PAMAM dendrimers.

Wang B, Navath RS, Menjoge AR, Balakrishnan B, Bellair R, Dai H, Romero R, Kannan S, Kannan RM.

Int J Pharm. 2010 Aug 16;395(1-2):298-308. doi: 10.1016/j.ijpharm.2010.05.030. Epub 2010 May 24.


Amino acid-functionalized dendrimers with heterobifunctional chemoselective peripheral groups for drug delivery applications.

Navath RS, Menjoge AR, Wang B, Romero R, Kannan S, Kannan RM.

Biomacromolecules. 2010 Jun 14;11(6):1544-63. doi: 10.1021/bm100186b.


Transport and biodistribution of dendrimers across human fetal membranes: implications for intravaginal administration of dendrimer-drug conjugates.

Menjoge AR, Navath RS, Asad A, Kannan S, Kim CJ, Romero R, Kannan RM.

Biomaterials. 2010 Jun;31(18):5007-21. doi: 10.1016/j.biomaterials.2010.02.075. Epub 2010 Mar 25.


Stimuli-responsive star poly(ethylene glycol) drug conjugates for improved intracellular delivery of the drug in neuroinflammation.

Navath RS, Wang B, Kannan S, Romero R, Kannan RM.

J Control Release. 2010 Mar 19;142(3):447-56. doi: 10.1016/j.jconrel.2009.10.035. Epub 2009 Nov 5.


Anti-inflammatory and anti-oxidant activity of anionic dendrimer-N-acetyl cysteine conjugates in activated microglial cells.

Wang B, Navath RS, Romero R, Kannan S, Kannan R.

Int J Pharm. 2009 Jul 30;377(1-2):159-68. doi: 10.1016/j.ijpharm.2009.04.050. Epub 2009 May 20.


Poly(amidoamine) dendrimer-drug conjugates with disulfide linkages for intracellular drug delivery.

Kurtoglu YE, Navath RS, Wang B, Kannan S, Romero R, Kannan RM.

Biomaterials. 2009 Apr;30(11):2112-21. doi: 10.1016/j.biomaterials.2008.12.054. Epub 2009 Jan 25.


Dendrimer-drug conjugates for tailored intracellular drug release based on glutathione levels.

Navath RS, Kurtoglu YE, Wang B, Kannan S, Romero R, Kannan RM.

Bioconjug Chem. 2008 Dec;19(12):2446-55. doi: 10.1021/bc800342d.


Beta-galactoside prodrugs of doxorubicin for application in antibody directed enzyme prodrug therapy/prodrug monotherapy.

Devalapally H, Navath RS, Yenamandra V, Akkinepally RR, Devarakonda RK.

Arch Pharm Res. 2007 Jun;30(6):723-32.


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