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Items: 1 to 50 of 63

1.

Optimization of culture conditions for the derivation and propagation of baboon (Papio anubis) induced pluripotent stem cells.

Navara CS, Chaudhari S, McCarrey JR.

PLoS One. 2018 Mar 1;13(3):e0193195. doi: 10.1371/journal.pone.0193195. eCollection 2018.

2.

Microbial co-infection alters macrophage polarization, phagosomal escape, and microbial killing.

Trivedi NH, Yu JJ, Hung CY, Doelger RP, Navara CS, Armitige LY, Seshu J, Sinai AP, Chambers JP, Guentzel MN, Arulanandam BP.

Innate Immun. 2018 Apr;24(3):152-162. doi: 10.1177/1753425918760180. Epub 2018 Feb 26.

PMID:
29482417
3.

Advantages of nonhuman primates as preclinical models for evaluating stem cell-based therapies for Parkinson's disease.

Grow DA, McCarrey JR, Navara CS.

Stem Cell Res. 2016 Sep;17(2):352-366. doi: 10.1016/j.scr.2016.08.013. Epub 2016 Aug 26. Review.

4.

Contribution of FcɛRI-associated vesicles to mast cell-macrophage communication following Francisella tularensis infection.

Rodriguez AR, Yu JJ, Navara C, Chambers JP, Guentzel MN, Arulanandam BP.

Innate Immun. 2016 Oct;22(7):567-74. doi: 10.1177/1753425916663639. Epub 2016 Aug 22.

PMID:
27554051
5.

Differentiation and Characterization of Dopaminergic Neurons From Baboon Induced Pluripotent Stem Cells.

Grow DA, Simmons DV, Gomez JA, Wanat MJ, McCarrey JR, Paladini CA, Navara CS.

Stem Cells Transl Med. 2016 Sep;5(9):1133-44. doi: 10.5966/sctm.2015-0073. Epub 2016 Jun 24.

6.

M-Cells Contribute to the Entry of an Oral Vaccine but Are Not Essential for the Subsequent Induction of Protective Immunity against Francisella tularensis.

Cunningham AL, Guentzel MN, Yu JJ, Hung CY, Forsthuber TG, Navara CS, Yagita H, Williams IR, Klose KE, Eaves-Pyles TD, Arulanandam BP.

PLoS One. 2016 Apr 21;11(4):e0153402. doi: 10.1371/journal.pone.0153402. eCollection 2016.

7.
8.

Derivation of induced pluripotent stem cells from the baboon: a nonhuman primate model for preclinical testing of stem cell therapies.

Navara CS, Hornecker J, Grow D, Chaudhari S, Hornsby PJ, Ichida JK, Eggan K, McCarrey JR.

Cell Reprogram. 2013 Dec;15(6):495-502. doi: 10.1089/cell.2012.0093. Epub 2013 Nov 4.

9.

Mesenchymal stem cell osteodifferentiation in response to alternating electric current.

Creecy CM, O'Neill CF, Arulanandam BP, Sylvia VL, Navara CS, Bizios R.

Tissue Eng Part A. 2013 Feb;19(3-4):467-74. doi: 10.1089/ten.TEA.2012.0091. Epub 2012 Nov 29.

10.

Mast cell TLR2 signaling is crucial for effective killing of Francisella tularensis.

Rodriguez AR, Yu JJ, Guentzel MN, Navara CS, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP.

J Immunol. 2012 Jun 1;188(11):5604-11. doi: 10.4049/jimmunol.1200039. Epub 2012 Apr 23.

11.

Cell cycle adaptations and maintenance of genomic integrity in embryonic stem cells and induced pluripotent stem cells.

Momčilović O, Navara C, Schatten G.

Results Probl Cell Differ. 2011;53:415-58. doi: 10.1007/978-3-642-19065-0_18. Review.

PMID:
21630155
12.

Interspecies chimera between primate embryonic stem cells and mouse embryos: monkey ESCs engraft into mouse embryos, but not post-implantation fetuses.

Simerly C, McFarland D, Castro C, Lin CC, Redinger C, Jacoby E, Mich-Basso J, Orwig K, Mills P, Ahrens E, Navara C, Schatten G.

Stem Cell Res. 2011 Jul;7(1):28-40. doi: 10.1016/j.scr.2011.03.002. Epub 2011 Mar 25.

13.

Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts.

Constantinescu D, Csoka AB, Navara CS, Schatten GP.

Exp Cell Res. 2010 Oct 15;316(17):2747-59. doi: 10.1016/j.yexcr.2010.05.015. Epub 2010 Jun 25.

PMID:
20599958
14.

Pluripotency genes overexpressed in primate embryonic stem cells are localized on homologues of human chromosomes 16, 17, 19, and X.

Ben-Yehudah A, Navara CS, Redinger CJ, Mich-Basso JD, Castro CA, Oliver S, Chensny LJ, Richards TJ, Kaminski N, Schatten G.

Stem Cell Res. 2010 Jan;4(1):25-37. doi: 10.1016/j.scr.2009.09.003. Epub 2009 Sep 17.

15.

Enhancement of human embryonic stem cell pluripotency through inhibition of the mitochondrial respiratory chain.

Varum S, Momcilović O, Castro C, Ben-Yehudah A, Ramalho-Santos J, Navara CS.

Stem Cell Res. 2009 Sep-Nov;3(2-3):142-56. doi: 10.1016/j.scr.2009.07.002. Epub 2009 Aug 3.

16.

Ionizing radiation induces ataxia telangiectasia mutated-dependent checkpoint signaling and G(2) but not G(1) cell cycle arrest in pluripotent human embryonic stem cells.

Momcilović O, Choi S, Varum S, Bakkenist C, Schatten G, Navara C.

Stem Cells. 2009 Aug;27(8):1822-35. doi: 10.1002/stem.123.

17.

Evaluating protocols for embryonic stem cell differentiation into insulin-secreting beta-cells using insulin II-GFP as a specific and noninvasive reporter.

Ben-Yehudah A, White C, Navara CS, Castro CA, Ize-Ludlow D, Shaffer B, Sukhwani M, Mathews CE, Chaillet JR, Witchel SF.

Cloning Stem Cells. 2009 Jun;11(2):245-57. doi: 10.1089/clo.2008.0074.

18.

Establishment and characterization of baboon embryonic stem cell lines: an Old World Primate model for regeneration and transplantation research.

Simerly CR, Navara CS, Castro CA, Turpin JC, Redinger CJ, Mich-Basso JD, Jacoby ES, Grund KJ, McFarland DA, Oliver SL, Ben-Yehudah A, Carlisle DL, Frost P, Penedo C, Hewitson L, Schatten G.

Stem Cell Res. 2009 May;2(3):178-87. doi: 10.1016/j.scr.2009.02.004. Epub 2009 Feb 21.

19.

Derivation and characterization of nonhuman primate embryonic stem cells.

Navara CS, Redinger C, Mich-Basso J, Oliver S, Ben-Yehudah A, Castro C, Simerly C.

Curr Protoc Stem Cell Biol. 2007 Jun;Chapter 1:Unit 1A.1. doi: 10.1002/9780470151808.sc01a01s1.

PMID:
18785157
20.

Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints.

Cirio MC, Ratnam S, Ding F, Reinhart B, Navara C, Chaillet JR.

BMC Dev Biol. 2008 Jan 25;8:9. doi: 10.1186/1471-213X-8-9.

21.

Pedigreed primate embryonic stem cells express homogeneous familial gene profiles.

Navara CS, Mich-Basso JD, Redinger CJ, Ben-Yehudah A, Jacoby E, Kovkarova-Naumovski E, Sukhwani M, Orwig K, Kaminski N, Castro CA, Simerly CR, Schatten G.

Stem Cells. 2007 Nov;25(11):2695-2704. doi: 10.1634/stemcells.2007-0286. Epub 2007 Jul 19.

22.

The analysis of mitochondria and mitochondrial DNA in human embryonic stem cells.

St John JC, Amaral A, Bowles E, Oliveira JF, Lloyd R, Freitas M, Gray HL, Navara CS, Oliveira G, Schatten GP, Spikings E, Ramalho-Santos J.

Methods Mol Biol. 2006;331:347-74.

PMID:
16881526
23.

Specific dynamic and noninvasive labeling of pancreatic beta cells in reporter mice.

Ben-Yehudah A, Reinhart B, Navara C, Kotzuk J, Witchel S, Schatten G, Chaillet JR.

Genesis. 2005 Dec;43(4):166-74.

PMID:
16283623
24.

The expression of mitochondrial DNA transcription factors during early cardiomyocyte in vitro differentiation from human embryonic stem cells.

St John JC, Ramalho-Santos J, Gray HL, Petrosko P, Rawe VY, Navara CS, Simerly CR, Schatten GP.

Cloning Stem Cells. 2005;7(3):141-53.

PMID:
16176124
25.

Culture of human embryonic stem cells.

Schatten G, Smith J, Navara C, Park JH, Pedersen R.

Nat Methods. 2005 Jun;2(6):455-63. No abstract available.

PMID:
16170868
27.

Embryogenesis and blastocyst development after somatic cell nuclear transfer in nonhuman primates: overcoming defects caused by meiotic spindle extraction.

Simerly C, Navara C, Hyun SH, Lee BC, Kang SK, Capuano S, Gosman G, Dominko T, Chong KY, Compton D, Hwang WS, Schatten G.

Dev Biol. 2004 Dec 15;276(2):237-52. Erratum in: Dev Biol. 2005 Feb 15;278(2):619.

28.
29.

Nuclear transfer in the rhesus monkey: opportunities and challenges.

Simerly CR, Navara CS.

Cloning Stem Cells. 2003;5(4):319-31. No abstract available.

PMID:
14733750
30.

Molecular correlates of primate nuclear transfer failures.

Simerly C, Dominko T, Navara C, Payne C, Capuano S, Gosman G, Chong KY, Takahashi D, Chace C, Compton D, Hewitson L, Schatten G.

Science. 2003 Apr 11;300(5617):297. No abstract available.

31.

Structure-based design of novel anticancer agents.

Uckun FM, Sudbeck EA, Mao C, Ghosh S, Liu XP, Vassilev AO, Navara CS, Narla RK.

Curr Cancer Drug Targets. 2001 May;1(1):59-71. Review.

PMID:
12188892
32.
33.

Thrombopoietin induces p-selectin expression on platelets and subsequent platelet/leukocyte interactions.

Tibbles HE, Navara CS, Hupke MA, Vassilev AO, Uckun FM.

Biochem Biophys Res Commun. 2002 Apr 12;292(4):987-91.

PMID:
11944912
34.

Expression of TEL-AML1 fusion transcripts and response to induction therapy in standard risk acute lymphoblastic leukemia.

Uckun FM, Pallisgaard N, Hokland P, Navara C, Narla R, Gaynon PS, Sather H, Heerema N.

Leuk Lymphoma. 2001 Jun;42(1-2):41-56.

PMID:
11699220
35.
36.

Spongistatins as tubulin targeting agents.

Uckun FM, Mao C, Jan ST, Huang H, Vassilev AO, Navara CS, Narla RK.

Curr Pharm Des. 2001 Sep;7(13):1291-6. Review.

PMID:
11472268
37.

Chemosensitivity of TEL-AML1 fusion transcript positive acute lymphoblastic leukemia cells.

Krishna Narla R, Navara C, Sarquis M, Uckun FM.

Leuk Lymphoma. 2001 May;41(5-6):615-23.

PMID:
11378579
38.

X-ray structure, solution properties, and biological activity profile of vanadocene(IV) acetylacetonate complex,.

Ghosh P, Ghosh S, Navara C, Narla RK, Benyumov A, Uckun FM.

J Inorg Biochem. 2001 Apr;84(3-4):241-53.

PMID:
11374587
39.

Vanadocenes as potent anti-proliferative agents disrupting mitotic spindle formation in cancer cells.

Navara CS, Benyumov A, Vassilev A, Narla RK, Ghosh P, Uckun FM.

Anticancer Drugs. 2001 Apr;12(4):369-76.

PMID:
11335794
40.

SPIKET and COBRA compounds as novel tubulin modulators with potent anticancer activity.

Uckun FM, Mao C, Jan ST, Huang H, Vassilev AO, Sudbeck EA, Navara CS, Narla RK.

Curr Opin Investig Drugs. 2000 Oct;1(2):252-6. Review.

PMID:
11249582
41.

Treatment of allergic asthma by targeting janus kinase 3-dependent leukotriene synthesis in mast cells with 4-(3', 5'-dibromo-4'-hydroxyphenyl)amino-6,7-dimethoxyquinazoline (WHI-P97).

Malaviya R, Chen CL, Navara C, Malaviya R, Liu XP, Keenan M, Waurzyniak B, Uckun FM.

J Pharmacol Exp Ther. 2000 Dec;295(3):912-26.

PMID:
11082424
42.

COBRA-1, a rationally-designed epoxy-THF containing compound with potent tubulin depolymerizing activity as a novel anticancer agent.

Jan ST, Mao C, Vassilev AO, Navara CS, Uckun FM.

Bioorg Med Chem Lett. 2000 Jun 5;10(11):1193-7.

PMID:
10866379
43.

A rationally designed anticancer drug targeting a unique binding cavity of tubulin.

Uckun FM, Mao C, Vassilev AO, Navara CS, Narla RK, Jan ST.

Bioorg Med Chem Lett. 2000 May 15;10(10):1015-8.

PMID:
10843205
44.

Bis(4,7-dimethyl-1,10-phenanthroline) sulfatooxovanadium(IV) as a novel apoptosis-inducing anticancer agent.

Narla RK, Dong Y, D'Cruz OJ, Navara C, Uckun FM.

Clin Cancer Res. 2000 Apr;6(4):1546-56.

45.

Expression of aberrantly spliced oncogenic ikaros isoforms in childhood acute lymphoblastic leukemia.

Sun L, Goodman PA, Wood CM, Crotty ML, Sensel M, Sather H, Navara C, Nachman J, Steinherz PG, Gaynon PS, Seibel N, Vassilev A, Juran BD, Reaman GH, Uckun FM.

J Clin Oncol. 1999 Dec;17(12):3753-66.

PMID:
10577847
46.
47.

Expression of dominant-negative Ikaros isoforms in T-cell acute lymphoblastic leukemia.

Sun L, Crotty ML, Sensel M, Sather H, Navara C, Nachman J, Steinherz PG, Gaynon PS, Seibel N, Mao C, Vassilev A, Reaman GH, Uckun FM.

Clin Cancer Res. 1999 Aug;5(8):2112-20.

48.

Pharmacokinetics and biologic activity of the novel mast cell inhibitor, 4-(3-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline in mice.

Chen CL, Malaviya R, Navara C, Chen H, Bechard B, Mitcheltree G, Liu XP, Uckun FM.

Pharm Res. 1999 Jan;16(1):117-22.

PMID:
9950289
49.

Expression of dominant-negative and mutant isoforms of the antileukemic transcription factor Ikaros in infant acute lymphoblastic leukemia.

Sun L, Heerema N, Crotty L, Wu X, Navara C, Vassilev A, Sensel M, Reaman GH, Uckun FM.

Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):680-5.

50.

Bruton's tyrosine kinase as an inhibitor of the Fas/CD95 death-inducing signaling complex.

Vassilev A, Ozer Z, Navara C, Mahajan S, Uckun FM.

J Biol Chem. 1999 Jan 15;274(3):1646-56.

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