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Items: 1 to 50 of 370

1.

New insights about vaccine effectiveness: Impact of attenuated PRRS-strain vaccination on heterologous strain transmission.

Chase-Topping M, Xie J, Pooley C, Trus I, Bonckaert C, Rediger K, Bailey RI, Brown H, Bitsouni V, Barrio MB, Gueguen S, Nauwynck H, Doeschl-Wilson A.

Vaccine. 2020 Mar 23;38(14):3050-3061. doi: 10.1016/j.vaccine.2020.02.015. Epub 2020 Feb 29.

PMID:
32122719
2.
3.

An Alphaherpesvirus Exploits Antimicrobial β-Defensins To Initiate Respiratory Tract Infection.

Van Cleemput J, Poelaert KCK, Laval K, Vanderheijden N, Dhaenens M, Daled S, Boyen F, Pasmans F, Nauwynck HJ.

J Virol. 2020 Mar 31;94(8). pii: e01676-19. doi: 10.1128/JVI.01676-19. Print 2020 Mar 31.

4.

Failure to Remove Bluetongue Serotype 8 Virus (BTV-8) From in vitro Produced and in vivo Derived Bovine Embryos and Subsequent Transmission of BTV-8 to Recipient Cows After Embryo Transfer.

Haegeman A, Vandaele L, De Leeuw I, Oliveira AP, Nauwynck H, Van Soom A, De Clercq K.

Front Vet Sci. 2019 Dec 5;6:432. doi: 10.3389/fvets.2019.00432. eCollection 2019.

5.

Porcine rotavirus mainly infects primary porcine enterocytes at the basolateral surface.

Cui T, Theuns S, Xie J, Nauwynck HJ.

Vet Res. 2019 Dec 19;50(1):110. doi: 10.1186/s13567-019-0728-x.

6.

S100A9 regulates porcine reproductive and respiratory syndrome virus replication by interacting with the viral nucleocapsid protein.

Song Z, Bai J, Liu X, Nauwynck H, Wu J, Liu X, Jiang P.

Vet Microbiol. 2019 Dec;239:108498. doi: 10.1016/j.vetmic.2019.108498. Epub 2019 Nov 6.

PMID:
31767072
7.

Therapeutic effect of Xanthohumol against highly pathogenic porcine reproductive and respiratory syndrome viruses.

Liu X, Bai J, Jiang C, Song Z, Zhao Y, Nauwynck H, Jiang P.

Vet Microbiol. 2019 Nov;238:108431. doi: 10.1016/j.vetmic.2019.108431. Epub 2019 Sep 26.

PMID:
31648725
8.

Xanthohumol inhibits PRRSV proliferation and alleviates oxidative stress induced by PRRSV via the Nrf2-HMOX1 axis.

Liu X, Song Z, Bai J, Nauwynck H, Zhao Y, Jiang P.

Vet Res. 2019 Sep 11;50(1):61. doi: 10.1186/s13567-019-0679-2.

9.

Charcot-Leyden crystals promote neutrophilic inflammation in patients with nasal polyposis.

Gevaert E, Delemarre T, De Volder J, Zhang N, Holtappels G, De Ruyck N, Persson E, Heyndrickx I, Verstraete K, Aegerter H, Nauwynck H, Savvides SN, Lambrecht BN, Bachert C.

J Allergy Clin Immunol. 2020 Jan;145(1):427-430.e4. doi: 10.1016/j.jaci.2019.08.027. Epub 2019 Sep 4. No abstract available.

PMID:
31493418
10.

Equine herpesvirus 1 infection orchestrates the expression of chemokines in equine respiratory epithelial cells.

Poelaert KCK, Van Cleemput J, Laval K, Xie J, Favoreel HW, Nauwynck HJ.

J Gen Virol. 2019 Nov;100(11):1567-1579. doi: 10.1099/jgv.0.001317.

PMID:
31490114
11.

No Evidence for a Role for Antibodies during Vaccination-Induced Enhancement of Porcine Reproductive and Respiratory Syndrome.

Sautter CA, Trus I, Nauwynck H, Summerfield A.

Viruses. 2019 Sep 6;11(9). pii: E829. doi: 10.3390/v11090829.

12.

Identification of peptide domains involved in the subcellular localization of the feline coronavirus 3b protein.

Acar DD, Stroobants VJE, Favoreel H, Saelens X, Nauwynck HJ.

J Gen Virol. 2019 Oct;100(10):1417-1430. doi: 10.1099/jgv.0.001321. Epub 2019 Aug 30.

13.

Strain-Dependent Porcine Circovirus Type 2 (PCV2) Entry and Replication in T-Lymphoblasts.

Wei R, Van Renne N, Nauwynck HJ.

Viruses. 2019 Sep 2;11(9). pii: E813. doi: 10.3390/v11090813.

14.

Changes on the viral capsid surface during the evolution of porcine circovirus type 2 (PCV2) from 2009 till 2018 may lead to a better receptor binding.

Wei R, Xie J, Theuns S, Nauwynck HJ.

Virus Evol. 2019 Aug 1;5(2):vez026. doi: 10.1093/ve/vez026. eCollection 2019 Jul.

15.

A DNA Prime Immuno-Potentiates a Modified Live Vaccine against the Porcine Reproductive and Respiratory Syndrome Virus but Does Not Improve Heterologous Protection.

Bernelin-Cottet C, Urien C, Fretaud M, Langevin C, Trus I, Jouneau L, Blanc F, Leplat JJ, Barc C, Boulesteix O, Riou M, Dysart M, Mahé S, Studsrub E, Nauwynck H, Bertho N, Bourry O, Schwartz-Cornil I.

Viruses. 2019 Jun 25;11(6). pii: E576. doi: 10.3390/v11060576.

16.

Deoxynivalenol, but not fumonisin B1, aflatoxin B1 or diesel exhaust particles disrupt integrity of the horse's respiratory epithelium and predispose it for equine herpesvirus type 1 infection.

Van Cleemput J, Poelaert KCK, Laval K, Van den Broeck W, Nauwynck HJ.

Vet Microbiol. 2019 Jul;234:17-24. doi: 10.1016/j.vetmic.2019.05.009. Epub 2019 May 9.

17.

Toll-like receptor agonists as adjuvants for inactivated porcine reproductive and respiratory syndrome virus (PRRSV) vaccine.

Vreman S, McCaffrey J, Popma-de Graaf DJ, Nauwynck H, Savelkoul HFJ, Moore A, Rebel JMJ, Stockhofe-Zurwieden N.

Vet Immunol Immunopathol. 2019 Jun;212:27-37. doi: 10.1016/j.vetimm.2019.04.008. Epub 2019 Apr 30.

18.

A DNA-Modified Live Vaccine Prime-Boost Strategy Broadens the T-Cell Response and Enhances the Antibody Response against the Porcine Reproductive and Respiratory Syndrome Virus.

Bernelin-Cottet C, Urien C, Stubsrud E, Jakob V, Bouguyon E, Bordet E, Barc C, Boulesteix O, Contreras V, Barnier-Quer C, Collin N, Trus I, Nauwynck H, Bertho N, Schwartz-Cornil I.

Viruses. 2019 Jun 14;11(6). pii: E551. doi: 10.3390/v11060551.

19.

Beyond Gut Instinct: Metabolic Short-Chain Fatty Acids Moderate the Pathogenesis of Alphaherpesviruses.

Poelaert KCK, Van Cleemput J, Laval K, Descamps S, Favoreel HW, Nauwynck HJ.

Front Microbiol. 2019 Apr 5;10:723. doi: 10.3389/fmicb.2019.00723. eCollection 2019.

20.

25-Hydroxycholesterol provides antiviral protection against highly pathogenic porcine reproductive and respiratory syndrome virus in swine.

Song Z, Bai J, Nauwynck H, Lin L, Liu X, Yu J, Jiang P.

Vet Microbiol. 2019 Apr;231:63-70. doi: 10.1016/j.vetmic.2019.02.035. Epub 2019 Feb 25.

PMID:
30955825
21.

Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection.

Van Cleemput J, Poelaert KCK, Laval K, Impens F, Van den Broeck W, Gevaert K, Nauwynck HJ.

Sci Rep. 2019 Mar 18;9(1):4787. doi: 10.1038/s41598-019-41305-y.

22.

ZAP, a CCCH-Type Zinc Finger Protein, Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication and Interacts with Viral Nsp9.

Zhao Y, Song Z, Bai J, Liu X, Nauwynck H, Jiang P.

J Virol. 2019 May 1;93(10). pii: e00001-19. doi: 10.1128/JVI.00001-19. Print 2019 May 15.

23.

Unravelling the first key steps in equine herpesvirus type 5 (EHV5) pathogenesis using ex vivo and in vitro equine models.

Van Cleemput J, Poelaert KCK, Laval K, Nauwynck HJ.

Vet Res. 2019 Feb 18;50(1):13. doi: 10.1186/s13567-019-0630-6.

24.

Gammaherpesvirus BoHV-4 infects bovine respiratory epithelial cells mainly at the basolateral side.

Yang B, Xie J, Van Cleemput J, Wei R, Opsomer G, Nauwynck HJ.

Vet Res. 2019 Feb 8;50(1):11. doi: 10.1186/s13567-019-0629-z.

25.

Equine Herpesvirus 1 Bridles T Lymphocytes To Reach Its Target Organs.

Poelaert KCK, Van Cleemput J, Laval K, Favoreel HW, Couck L, Van den Broeck W, Azab W, Nauwynck HJ.

J Virol. 2019 Mar 21;93(7). pii: e02098-18. doi: 10.1128/JVI.02098-18. Print 2019 Apr 1.

26.

Presence of gammaherpesvirus BoHV-4 in endometrial cytology samples is not associated with subclinical endometritis diagnosed at artificial insemination in dairy cows.

Yang B, Pascottini OB, Xie J, Desmarets L, Cui T, Opsomer G, Nauwynck HJ.

Vet Microbiol. 2019 Feb;229:130-137. doi: 10.1016/j.vetmic.2018.12.025. Epub 2018 Dec 28.

PMID:
30642588
27.

A Triple Amino Acid Substitution at Position 88/94/95 in Glycoprotein GP2a of Type 1 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV1) Is Responsible for Adaptation to MARC-145 Cells.

Xie J, Trus I, Oh D, Kvisgaard LK, Rappe JCF, Ruggli N, Vanderheijden N, Larsen LE, Lefèvre F, Nauwynck HJ.

Viruses. 2019 Jan 8;11(1). pii: E36. doi: 10.3390/v11010036.

28.

Dissecting clinical outcome of porcine circovirus type 2 with in vivo derived transcriptomic signatures of host tissue responses.

Van Renne N, Wei R, Pochet N, Nauwynck HJ.

BMC Genomics. 2018 Nov 20;19(1):831. doi: 10.1186/s12864-018-5217-5.

29.

Breed Differences in PCV2 Uptake and Disintegration in Porcine Monocytes.

Wei R, Trus I, Yang B, Huang L, Nauwynck HJ.

Viruses. 2018 Oct 15;10(10). pii: E562. doi: 10.3390/v10100562.

30.

Establishment of porcine enterocyte/myofibroblast co-cultures for the growth of porcine rota- and coronaviruses.

Cui T, Theuns S, Desmarets LMB, Xie J, De Gryse GMA, Yang B, Van den Broeck W, Nauwynck HJ.

Sci Rep. 2018 Oct 12;8(1):15195. doi: 10.1038/s41598-018-33305-1.

31.

Abortigenic but Not Neurotropic Equine Herpes Virus 1 Modulates the Interferon Antiviral Defense.

Poelaert KCK, Van Cleemput J, Laval K, Favoreel HW, Soboll Hussey G, Maes RK, Nauwynck HJ.

Front Cell Infect Microbiol. 2018 Sep 12;8:312. doi: 10.3389/fcimb.2018.00312. eCollection 2018.

32.

Preferential use of Siglec-1 or Siglec-10 by type 1 and type 2 PRRSV strains to infect PK15S1-CD163 and PK15S10-CD163 cells.

Xie J, Christiaens I, Yang B, Trus I, Devriendt B, Cui T, Wei R, Nauwynck HJ.

Vet Res. 2018 Jul 18;49(1):67. doi: 10.1186/s13567-018-0569-z.

33.

Nanopore sequencing as a revolutionary diagnostic tool for porcine viral enteric disease complexes identifies porcine kobuvirus as an important enteric virus.

Theuns S, Vanmechelen B, Bernaert Q, Deboutte W, Vandenhole M, Beller L, Matthijnssens J, Maes P, Nauwynck HJ.

Sci Rep. 2018 Jun 29;8(1):9830. doi: 10.1038/s41598-018-28180-9.

34.

Introduction to Virology special issue featuring nidovirus research.

Fang Y, Baker S, Snijder E, Gallagher T, Makino S, Nauwynck H.

Virology. 2018 Apr;517:1-2. doi: 10.1016/j.virol.2018.03.003. No abstract available.

35.

Access to a main alphaherpesvirus receptor, located basolaterally in the respiratory epithelium, is masked by intercellular junctions.

Van Cleemput J, Poelaert KCK, Laval K, Maes R, Hussey GS, Van den Broeck W, Nauwynck HJ.

Sci Rep. 2017 Nov 30;7(1):16656. doi: 10.1038/s41598-017-16804-5.

36.

Primary replication and invasion of the bovine gammaherpesvirus BoHV-4 in the genital mucosae.

Yang B, Li Y, Bogado Pascottini O, Xie J, Wei R, Opsomer G, Nauwynck H.

Vet Res. 2017 Nov 28;48(1):83. doi: 10.1186/s13567-017-0489-3.

37.

Genetic and pathogenic characterization of a Russian subtype 2 PRRSV-1 isolate.

Yuzhakov AG, Raev SA, Skrylev AN, Mishin AM, Grebennikova TV, Verkhovsky OA, Zaberezhny AD, Trus I, Nauwynck HJ, Aliper TI.

Vet Microbiol. 2017 Nov;211:22-28. doi: 10.1016/j.vetmic.2017.09.017. Epub 2017 Sep 22.

PMID:
29102117
38.
39.

Identification of an enterovirus recombinant with a torovirus-like gene insertion during a diarrhea outbreak in fattening pigs.

Conceição-Neto N, Theuns S, Cui T, Zeller M, Yinda CK, Christiaens I, Heylen E, Van Ranst M, Carpentier S, Nauwynck HJ, Matthijnssens J.

Virus Evol. 2017 Sep 8;3(2):vex024. doi: 10.1093/ve/vex024. eCollection 2017 Jul.

40.

Long-term culture and differentiation of porcine red bone marrow hematopoietic cells co-cultured with immortalized mesenchymal cells.

Garba A, Acar DD, Roukaerts IDM, Desmarets LMB, Devriendt B, Nauwynck HJ.

Vet Immunol Immunopathol. 2017 Sep;191:44-50. doi: 10.1016/j.vetimm.2017.08.002. Epub 2017 Aug 7.

PMID:
28895865
41.

The complex co-translational processing of glycoprotein GP5 of type 1 porcine reproductive and respiratory syndrome virus.

Thaa B, Kaufer S, Neumann SA, Peibst B, Nauwynck H, Krause E, Veit M.

Virus Res. 2017 Aug 15;240:112-120. doi: 10.1016/j.virusres.2017.08.004. Epub 2017 Aug 12.

PMID:
28807563
42.

Molecular cloning of porcine Siglec-3, Siglec-5 and Siglec-10, and identification of Siglec-10 as an alternative receptor for porcine reproductive and respiratory syndrome virus (PRRSV).

Xie J, Christiaens I, Yang B, Breedam WV, Cui T, Nauwynck HJ.

J Gen Virol. 2017 Aug;98(8):2030-2042. doi: 10.1099/jgv.0.000859. Epub 2017 Jul 26.

43.

Us3 and Us9 proteins contribute to the stromal invasion of bovine herpesvirus 1 in the respiratory mucosa.

Zhao J, Poelaert KCK, Steukers L, Favoreel HW, Li Y, Chowdhury SI, van Drunen Littel-van den Hurk S, Caij B, Nauwynck HJ.

J Gen Virol. 2017 May;98(5):1089-1096. doi: 10.1099/jgv.0.000764.

PMID:
28516841
44.

Modified-live PRRSV subtype 1 vaccine UNISTRAIN® PRRS provides a partial clinical and virological protection upon challenge with East European subtype 3 PRRSV strain Lena.

Bonckaert C, van der Meulen K, Rodríguez-Ballarà I, Pedrazuela Sanz R, Martinez MF, Nauwynck HJ.

Porcine Health Manag. 2016 May 9;2:12. doi: 10.1186/s40813-016-0029-y. eCollection 2016.

46.

Extracellular eosinophilic traps in association with Staphylococcus aureus at the site of epithelial barrier defects in patients with severe airway inflammation.

Gevaert E, Zhang N, Krysko O, Lan F, Holtappels G, De Ruyck N, Nauwynck H, Yousefi S, Simon HU, Bachert C.

J Allergy Clin Immunol. 2017 Jun;139(6):1849-1860.e6. doi: 10.1016/j.jaci.2017.01.019. Epub 2017 Feb 17.

PMID:
28216437
47.

Replication of neurovirulent equine herpesvirus type 1 (EHV-1) in CD172a+ monocytic cells.

Laval K, Van Cleemput J, Poelaert KC, Brown IK, Nauwynck HJ.

Comp Immunol Microbiol Infect Dis. 2017 Feb;50:58-62. doi: 10.1016/j.cimid.2016.11.006. Epub 2016 Nov 15.

PMID:
28131380
48.

Hampered cumulus expansion of porcine cumulus-oocyte complexes by excessive presence of alpha2 -macroglobulin is likely mediated via inhibition of zinc-dependent metalloproteases.

Appeltant R, Beek J, Maes D, Bijttebier J, Van Steendam K, Nauwynck H, Van Soom A.

Anim Sci J. 2017 Sep;88(9):1279-1290. doi: 10.1111/asj.12767. Epub 2017 Jan 26.

PMID:
28124491
49.

Detection of Equine Herpesvirus (EHV) -1, -2, -4 and -5 in Ethiopian Equids with and without Respiratory Problems and Genetic Characterization of EHV-2 and EHV-5 Strains.

Negussie H, Gizaw D, Tesfaw L, Li Y, Oguma K, Sentsui H, Tessema TS, Nauwynck HJ.

Transbound Emerg Dis. 2017 Dec;64(6):1970-1978. doi: 10.1111/tbed.12601. Epub 2017 Jan 18.

PMID:
28102009
50.

Monoclonal antibody binding to the macrophage-specific receptor sialoadhesin alters the phagocytic properties of human and mouse macrophages.

De Schryver M, Cappoen D, Elewaut D, Nauwynck HJ, Maes L, Caljon G, Cos P, Delputte PL.

Cell Immunol. 2017 Feb;312:51-60. doi: 10.1016/j.cellimm.2016.11.009. Epub 2016 Dec 9.

PMID:
27993350

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