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Items: 1 to 50 of 341

1.

Nuclear RNA export factor variant initiates piRNA-guided co-transcriptional silencing.

Murano K, Iwasaki YW, Ishizu H, Mashiko A, Shibuya A, Kondo S, Adachi S, Suzuki S, Saito K, Natsume T, Siomi MC, Siomi H.

EMBO J. 2019 Aug 1:e102870. doi: 10.15252/embj.2019102870. [Epub ahead of print]

PMID:
31368590
2.

Two distinct nuclear stress bodies containing different sets of RNA-binding proteins are formed with HSATIII architectural noncoding RNAs upon thermal stress exposure.

Aly MK, Ninomiya K, Adachi S, Natsume T, Hirose T.

Biochem Biophys Res Commun. 2019 Aug 20;516(2):419-423. doi: 10.1016/j.bbrc.2019.06.061. Epub 2019 Jun 18.

PMID:
31227213
3.

FAM48A mediates compensatory autophagy induced by proteasome impairment.

Arata Y, Watanabe A, Motosugi R, Iemura SI, Natsume T, Mukai K, Taguchi T, Hirayama S, Hamazaki J, Murata S.

Genes Cells. 2019 Aug;24(8):559-568. doi: 10.1111/gtc.12708. Epub 2019 Jul 3.

PMID:
31210371
4.

Detection of Transgenes in Gene Delivery Model Mice by Adenoviral Vector Using ddPCR.

Sugasawa T, Aoki K, Watanabe K, Yanazawa K, Natsume T, Takemasa T, Yamaguchi K, Takeuchi Y, Aita Y, Yahagi N, Yoshida Y, Tokinoya K, Sekine N, Takeuchi K, Ueda H, Kawakami Y, Shimizu S, Takekoshi K.

Genes (Basel). 2019 Jun 8;10(6). pii: E436. doi: 10.3390/genes10060436.

5.

[A Case of Boderline Resectable Pancreatic Cancer Curatively Resected after Chemotherapy with Gemcitabine and Nab-Paclitaxel].

Kuwayama N, Natsume T, Kainuma O, Maruyama T, Tanaka H, Miyazaki A, Sato Y, Note H, Yoshioka T, Matsumoto Y, Suzuki K, Kato M, Oshima S, Ishigaki A, Mizumoto H, Shimizu S.

Gan To Kagaku Ryoho. 2019 Apr;46(4):721-724. Japanese.

PMID:
31164515
6.

HsSAS-6-dependent cartwheel assembly ensures stabilization of centriole intermediates.

Yoshiba S, Tsuchiya Y, Ohta M, Gupta A, Shiratsuchi G, Nozaki Y, Ashikawa T, Fujiwara T, Natsume T, Kanemaki MT, Kitagawa D.

J Cell Sci. 2019 Jun 20;132(12). pii: jcs217521. doi: 10.1242/jcs.217521.

PMID:
31164447
7.

Generation of conditional auxin-inducible degron (AID) cells and tight control of degron-fused proteins using the degradation inhibitor auxinole.

Yesbolatova A, Natsume T, Hayashi KI, Kanemaki MT.

Methods. 2019 Jul 15;164-165:73-80. doi: 10.1016/j.ymeth.2019.04.010. Epub 2019 Apr 24.

8.

Intrinsically Disordered Protein TEX264 Mediates ER-phagy.

Chino H, Hatta T, Natsume T, Mizushima N.

Mol Cell. 2019 Jun 6;74(5):909-921.e6. doi: 10.1016/j.molcel.2019.03.033. Epub 2019 Apr 18.

PMID:
31006538
9.

Association between locomotive syndrome and blood parameters in Japanese middle-aged and elderly individuals: a cross-sectional study.

Yoshihara T, Ozaki H, Nakagata T, Natsume T, Kitada T, Ishihara Y, Sawada S, Ishibashi M, Kobayashi H, Machida S, Naito H.

BMC Musculoskelet Disord. 2019 Mar 14;20(1):104. doi: 10.1186/s12891-019-2480-9.

10.

Distinguishing analgesic drugs from non-analgesic drugs based on brain activation in macaques with oxaliplatin-induced neuropathic pain.

Shidahara Y, Natsume T, Awaga Y, Ogawa S, Yamoto K, Okamoto S, Hama A, Hayashi I, Takamatsu H, Magata Y.

Neuropharmacology. 2019 May 1;149:204-211. doi: 10.1016/j.neuropharm.2019.02.031. Epub 2019 Feb 25.

PMID:
30817933
11.

Inhibiting the MCM8-9 complex selectively sensitizes cancer cells to cisplatin and olaparib.

Morii I, Iwabuchi Y, Mori S, Suekuni M, Natsume T, Yoshida K, Sugimoto N, Kanemaki MT, Fujita M.

Cancer Sci. 2019 Mar;110(3):1044-1053. doi: 10.1111/cas.13941. Epub 2019 Feb 14.

12.

Chk1-mediated Cdc25A degradation as a critical mechanism for normal cell cycle progression.

Goto H, Natsume T, Kanemaki MT, Kaito A, Wang S, Gabazza EC, Inagaki M, Mizoguchi A.

J Cell Sci. 2019 Jan 25;132(2). pii: jcs223123. doi: 10.1242/jcs.223123.

13.

Pain-related behavior and brain activation in cynomolgus macaques with naturally occurring endometriosis.

Yano M, Matsuda A, Natsume T, Ogawa S, Awaga Y, Hayashi I, Hama A, Takamatsu H.

Hum Reprod. 2019 Mar 1;34(3):469-478. doi: 10.1093/humrep/dey383.

PMID:
30597044
14.

MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs.

Okamoto K, Ohishi T, Kuroiwa M, Iemura SI, Natsume T, Seimiya H.

Oncotarget. 2018 Nov 9;9(88):35844-35855. doi: 10.18632/oncotarget.26312. eCollection 2018 Nov 9.

15.

Synthesis and biological evaluation of thielocin B1 analogues as protein-protein interaction inhibitors of PAC3 homodimer.

Ohsawa K, Yoshida M, Izumikawa M, Takagi M, Shin-Ya K, Goshima N, Hirokawa T, Natsume T, Doi T.

Bioorg Med Chem. 2018 Dec 15;26(23-24):6023-6034. doi: 10.1016/j.bmc.2018.11.001. Epub 2018 Nov 7.

PMID:
30455074
16.

Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B.

Hatta T, Iemura SI, Ohishi T, Nakayama H, Seimiya H, Yasuda T, Iizuka K, Fukuda M, Takeda J, Natsume T, Horikawa Y.

Sci Rep. 2018 Nov 13;8(1):16756. doi: 10.1038/s41598-018-35204-x.

17.

Electromyostimulation with blood flow restriction enhances activation of mTOR and MAPK signaling pathways in rat gastrocnemius muscles.

Natsume T, Yoshihara T, Naito H.

Appl Physiol Nutr Metab. 2019 Jun;44(6):637-644. doi: 10.1139/apnm-2018-0384. Epub 2018 Nov 6.

PMID:
30398900
18.

Sex differences in forkhead box O3a signaling response to hindlimb unloading in rat soleus muscle.

Yoshihara T, Natsume T, Tsuzuki T, Chang SW, Kakigi R, Sugiura T, Naito H.

J Physiol Sci. 2019 Mar;69(2):235-244. doi: 10.1007/s12576-018-0640-6. Epub 2018 Sep 27.

PMID:
30259391
19.

Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase.

Yoneyama Y, Inamitsu T, Chida K, Iemura SI, Natsume T, Maeda T, Hakuno F, Takahashi SI.

iScience. 2018 Jul 27;5:1-18. doi: 10.1016/j.isci.2018.06.006. Epub 2018 Jun 18.

20.

Effects of a progressive walking program on the risk of developing locomotive syndrome in elderly Japanese people: a single-arm trial.

Yoshihara T, Ozaki H, Nakagata T, Natsume T, Kitada T, Ishihara Y, Deng P, Osawa T, Ishibashi M, Ishijima M, Kobayashi H, Machida S, Naito H.

J Phys Ther Sci. 2018 Sep;30(9):1180-1186. doi: 10.1589/jpts.30.1180. Epub 2018 Sep 4.

21.

[Pharmacological profile of a novel nonhuman primate model of knee osteoarthritis].

Ogawa S, Natsume T, Takamatsu H.

Nihon Yakurigaku Zasshi. 2018;152(3):132-138. doi: 10.1254/fpj.152.132. Japanese.

PMID:
30185731
22.

Combinatorial CRISPR/Cas9 Approach to Elucidate a Far-Upstream Enhancer Complex for Tissue-Specific Sox9 Expression.

Mochizuki Y, Chiba T, Kataoka K, Yamashita S, Sato T, Kato T, Takahashi K, Miyamoto T, Kitazawa M, Hatta T, Natsume T, Takai S, Asahara H.

Dev Cell. 2018 Sep 24;46(6):794-806.e6. doi: 10.1016/j.devcel.2018.07.024. Epub 2018 Aug 23.

PMID:
30146478
23.

Seasonal variation of energy expenditure in Japanese macaques (Macaca fuscata).

Sha JCM, Kurihara Y, Tsuji Y, Take M, He T, Kaneko A, Suda-Hashimoto N, Morimoto M, Natsume T, Zahariev A, Blanc S, Hanya G.

J Therm Biol. 2018 Aug;76:139-146. doi: 10.1016/j.jtherbio.2018.07.009. Epub 2018 Jul 25.

PMID:
30143288
24.

β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.

Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K.

Biochim Biophys Acta Gen Subj. 2018 Oct;1862(10):2271-2280. doi: 10.1016/j.bbagen.2018.07.015. Epub 2018 Jul 18.

PMID:
30031111
25.

Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma.

Kim Y, Shiba-Ishii A, Nakagawa T, Iemura SI, Natsume T, Nakano N, Matsuoka R, Sakashita S, Lee S, Kawaguchi A, Sato Y, Noguchi M.

Oncogene. 2018 Oct;37(40):5387-5402. doi: 10.1038/s41388-018-0342-9. Epub 2018 Jun 7.

PMID:
29880877
26.

Gaps in Understanding Mechanism and Lack of Treatments: Potential Use of a Nonhuman Primate Model of Oxaliplatin-Induced Neuropathic Pain.

Hama A, Natsume T, Ogawa S, Higo N, Hayashi I, Takamatsu H.

Pain Res Manag. 2018 May 2;2018:1630709. doi: 10.1155/2018/1630709. eCollection 2018. Review.

27.

Dynein-Dynactin-NuMA clusters generate cortical spindle-pulling forces as a multi-arm ensemble.

Okumura M, Natsume T, Kanemaki MT, Kiyomitsu T.

Elife. 2018 May 31;7. pii: e36559. doi: 10.7554/eLife.36559.

28.

Pain-Related Behavior and Brain Activation in a Cynomolgus Macaque Model of Postoperative Pain.

Hama A, Natsume T, Ogawa SY, Awaga Y, Hayashi I, Matsuda A, Takamatsu H.

CNS Neurol Disord Drug Targets. 2018;17(5):348-360. doi: 10.2174/1871527317666180515121350.

PMID:
29766827
29.

Effects of training intensity in electromyostimulation on human skeletal muscle.

Natsume T, Ozaki H, Kakigi R, Kobayashi H, Naito H.

Eur J Appl Physiol. 2018 Jul;118(7):1339-1347. doi: 10.1007/s00421-018-3866-3. Epub 2018 Apr 20.

PMID:
29679248
30.

Nuclear export of ubiquitinated proteins via the UBIN-POST system.

Hirayama S, Sugihara M, Morito D, Iemura SI, Natsume T, Murata S, Nagata K.

Proc Natl Acad Sci U S A. 2018 May 1;115(18):E4199-E4208. doi: 10.1073/pnas.1711017115. Epub 2018 Apr 16.

31.

Hepatomegaly in a boy with ARID1B-related Coffin-Siris syndrome.

Natsume T, Takano K, Motobayashi M, Kosho T.

Pediatr Int. 2018 Apr;60(4):378-380. doi: 10.1111/ped.13508. Epub 2018 Mar 4. No abstract available.

PMID:
29504208
32.

Ki-67 and condensins support the integrity of mitotic chromosomes through distinct mechanisms.

Takagi M, Ono T, Natsume T, Sakamoto C, Nakao M, Saitoh N, Kanemaki MT, Hirano T, Imamoto N.

J Cell Sci. 2018 Mar 22;131(6). pii: jcs212092. doi: 10.1242/jcs.212092.

33.

ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.

Noguchi A, Adachi S, Yokota N, Hatta T, Natsume T, Kawahara H.

Biol Open. 2018 Mar 12;7(3). pii: bio031575. doi: 10.1242/bio.031575.

34.

The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.

Yamaguchi T, Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, Natsui M, Inagaki H, Arakawa S, Nakaoka S, Koizumi Y, Seki S, Adachi S, Fukao A, Fujiwara T, Natsume T, Kimura A, Komatsu M, Shimizu S, Ito H, Suzuki Y, Penninger JM, Yamamoto T, Imai Y, Kuba K.

Sci Signal. 2018 Feb 6;11(516). pii: eaan3638. doi: 10.1126/scisignal.aan3638.

PMID:
29438013
35.

Xrn2 accelerates termination by RNA polymerase II, which is underpinned by CPSF73 activity.

Eaton JD, Davidson L, Bauer DLV, Natsume T, Kanemaki MT, West S.

Genes Dev. 2018 Jan 15;32(2):127-139. doi: 10.1101/gad.308528.117. Epub 2018 Feb 8.

36.

Characterization of extracellular matrix components from the desiccation-tolerant cyanobacterium Nostoc commune.

Inoue-Sakamoto K, Tanji Y, Yamaba M, Natsume T, Masaura T, Asano T, Nishiuchi T, Sakamoto T.

J Gen Appl Microbiol. 2018 Mar 27;64(1):15-25. doi: 10.2323/jgam.2017.03.001. Epub 2017 Dec 8.

37.

TRIM48 Promotes ASK1 Activation and Cell Death through Ubiquitination-Dependent Degradation of the ASK1-Negative Regulator PRMT1.

Hirata Y, Katagiri K, Nagaoka K, Morishita T, Kudoh Y, Hatta T, Naguro I, Kano K, Udagawa T, Natsume T, Aoki J, Inada T, Noguchi T, Ichijo H, Matsuzawa A.

Cell Rep. 2017 Nov 28;21(9):2447-2457. doi: 10.1016/j.celrep.2017.11.007.

38.

Conditional Degrons for Controlling Protein Expression at the Protein Level.

Natsume T, Kanemaki MT.

Annu Rev Genet. 2017 Nov 27;51:83-102. doi: 10.1146/annurev-genet-120116-024656. Review.

PMID:
29178817
39.

Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells.

Matsudaira T, Mukai K, Noguchi T, Hasegawa J, Hatta T, Iemura SI, Natsume T, Miyamura N, Nishina H, Nakayama J, Semba K, Tomita T, Murata S, Arai H, Taguchi T.

Nat Commun. 2017 Nov 1;8(1):1246. doi: 10.1038/s41467-017-01255-3.

40.

A small-molecule compound inhibits a collagen-specific molecular chaperone and could represent a potential remedy for fibrosis.

Ito S, Ogawa K, Takeuchi K, Takagi M, Yoshida M, Hirokawa T, Hirayama S, Shin-Ya K, Shimada I, Doi T, Goshima N, Natsume T, Nagata K.

J Biol Chem. 2017 Dec 8;292(49):20076-20085. doi: 10.1074/jbc.M117.815936. Epub 2017 Oct 12.

41.

Multiple regulatory mechanisms of the biological function of NRF3 (NFE2L3) control cancer cell proliferation.

Chowdhury AMMA, Katoh H, Hatanaka A, Iwanari H, Nakamura N, Hamakubo T, Natsume T, Waku T, Kobayashi A.

Sci Rep. 2017 Oct 2;7(1):12494. doi: 10.1038/s41598-017-12675-y.

42.

Determination of Rate-Limiting Factor for Formation of Beta-Catenin Destruction Complexes Using Absolute Protein Quantification.

Kitazawa M, Hatta T, Ogawa K, Fukuda E, Goshima N, Natsume T.

J Proteome Res. 2017 Oct 6;16(10):3576-3584. doi: 10.1021/acs.jproteome.7b00305. Epub 2017 Sep 1.

PMID:
28810742
43.

Endoplasmic reticulum proteins SDF2 and SDF2L1 act as components of the BiP chaperone cycle to prevent protein aggregation.

Fujimori T, Suno R, Iemura SI, Natsume T, Wada I, Hosokawa N.

Genes Cells. 2017 Aug;22(8):684-698. doi: 10.1111/gtc.12506. Epub 2017 Jun 9.

44.

Loss of Parkinson's disease-associated protein CHCHD2 affects mitochondrial crista structure and destabilizes cytochrome c.

Meng H, Yamashita C, Shiba-Fukushima K, Inoshita T, Funayama M, Sato S, Hatta T, Natsume T, Umitsu M, Takagi J, Imai Y, Hattori N.

Nat Commun. 2017 Jun 7;8:15500. doi: 10.1038/ncomms15500.

45.

Effects of drop sets with resistance training on increases in muscle CSA, strength, and endurance: a pilot study.

Ozaki H, Kubota A, Natsume T, Loenneke JP, Abe T, Machida S, Naito H.

J Sports Sci. 2018 Mar;36(6):691-696. doi: 10.1080/02640414.2017.1331042. Epub 2017 May 22.

PMID:
28532248
46.

Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis.

Natsume T, Nishimura K, Minocherhomji S, Bhowmick R, Hickson ID, Kanemaki MT.

Genes Dev. 2017 Apr 15;31(8):816-829. doi: 10.1101/gad.297663.117. Epub 2017 May 9.

47.

Robotic crowd biology with Maholo LabDroids.

Yachie N; Robotic Biology Consortium, Natsume T.

Nat Biotechnol. 2017 Apr 11;35(4):310-312. doi: 10.1038/nbt.3758. No abstract available.

PMID:
28398329
48.

Alternative exon skipping biases substrate preference of the deubiquitylase USP15 for mysterin/RNF213, the moyamoya disease susceptibility factor.

Kotani Y, Morito D, Sakata K, Ainuki S, Sugihara M, Hatta T, Iemura SI, Takashima S, Natsume T, Nagata K.

Sci Rep. 2017 Mar 9;7:44293. doi: 10.1038/srep44293.

49.

A large-scale targeted proteomics assay resource based on an in vitro human proteome.

Matsumoto M, Matsuzaki F, Oshikawa K, Goshima N, Mori M, Kawamura Y, Ogawa K, Fukuda E, Nakatsumi H, Natsume T, Fukui K, Horimoto K, Nagashima T, Funayama R, Nakayama K, Nakayama KI.

Nat Methods. 2017 Mar;14(3):251-258. doi: 10.1038/nmeth.4116. Epub 2016 Dec 26.

PMID:
28267743
50.

Tankyrase-Binding Protein TNKS1BP1 Regulates Actin Cytoskeleton Rearrangement and Cancer Cell Invasion.

Ohishi T, Yoshida H, Katori M, Migita T, Muramatsu Y, Miyake M, Ishikawa Y, Saiura A, Iemura SI, Natsume T, Seimiya H.

Cancer Res. 2017 May 1;77(9):2328-2338. doi: 10.1158/0008-5472.CAN-16-1846. Epub 2017 Feb 15.

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