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Items: 28


Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer.

Nadauld LD, Garcia S, Natsoulis G, Bell JM, Miotke L, Hopmans ES, Xu H, Pai RK, Palm C, Regan JF, Chen H, Flaherty P, Ootani A, Zhang NR, Ford JM, Kuo CJ, Ji HP.

Genome Biol. 2014 Aug 27;15(8):428. doi: 10.1186/s13059-014-0428-9.


A programmable method for massively parallel targeted sequencing.

Hopmans ES, Natsoulis G, Bell JM, Grimes SM, Sieh W, Ji HP.

Nucleic Acids Res. 2014 Jun;42(10):e88. doi: 10.1093/nar/gku282. Epub 2014 Apr 29.


Identification of Insertion Deletion Mutations from Deep Targeted Resequencing.

Natsoulis G, Zhang N, Welch K, Bell J, Ji HP.

J Data Mining Genomics Proteomics. 2013 Jul 2;4(3). pii: 1000132.


Performance comparison of whole-genome sequencing platforms.

Lam HY, Clark MJ, Chen R, Chen R, Natsoulis G, O'Huallachain M, Dewey FE, Habegger L, Ashley EA, Gerstein MB, Butte AJ, Ji HP, Snyder M.

Nat Biotechnol. 2011 Dec 18;30(1):78-82. doi: 10.1038/nbt.2065. Erratum in: Nat Biotechnol. 2012 Jun;30(6):562.


Targeted sequencing library preparation by genomic DNA circularization.

Myllykangas S, Natsoulis G, Bell JM, Ji HP.

BMC Biotechnol. 2011 Dec 14;11:122. doi: 10.1186/1472-6750-11-122.


The Human OligoGenome Resource: a database of oligonucleotide capture probes for resequencing target regions across the human genome.

Newburger DE, Natsoulis G, Grimes S, Bell JM, Davis RW, Batzoglou S, Ji HP.

Nucleic Acids Res. 2012 Jan;40(Database issue):D1137-43. doi: 10.1093/nar/gkr973. Epub 2011 Nov 18.


A cross-sample statistical model for SNP detection in short-read sequencing data.

Muralidharan O, Natsoulis G, Bell J, Newburger D, Xu H, Kela I, Ji H, Zhang N.

Nucleic Acids Res. 2012 Jan;40(1):e5. doi: 10.1093/nar/gkr851. Epub 2011 Nov 7.


Efficient targeted resequencing of human germline and cancer genomes by oligonucleotide-selective sequencing.

Myllykangas S, Buenrostro JD, Natsoulis G, Bell JM, Ji HP.

Nat Biotechnol. 2011 Oct 23;29(11):1024-7. doi: 10.1038/nbt.1996.


Ultrasensitive detection of rare mutations using next-generation targeted resequencing.

Flaherty P, Natsoulis G, Muralidharan O, Winters M, Buenrostro J, Bell J, Brown S, Holodniy M, Zhang N, Ji HP.

Nucleic Acids Res. 2012 Jan;40(1):e2. doi: 10.1093/nar/gkr861. Epub 2011 Oct 19.


A flexible approach for highly multiplexed candidate gene targeted resequencing.

Natsoulis G, Bell JM, Xu H, Buenrostro JD, Ordonez H, Grimes S, Newburger D, Jensen M, Zahn JM, Zhang N, Ji HP.

PLoS One. 2011;6(6):e21088. doi: 10.1371/journal.pone.0021088. Epub 2011 Jun 30.


The liver pharmacological and xenobiotic gene response repertoire.

Natsoulis G, Pearson CI, Gollub J, P Eynon B, Ferng J, Nair R, Idury R, Lee MD, Fielden MR, Brennan RJ, Roter AH, Jarnagin K.

Mol Syst Biol. 2008;4:175. doi: 10.1038/msb.2008.9. Epub 2008 Mar 25.


A gene expression signature that predicts the future onset of drug-induced renal tubular toxicity.

Fielden MR, Eynon BP, Natsoulis G, Jarnagin K, Banas D, Kolaja KL.

Toxicol Pathol. 2005;33(6):675-83.


Development of a large-scale chemogenomics database to improve drug candidate selection and to understand mechanisms of chemical toxicity and action.

Ganter B, Tugendreich S, Pearson CI, Ayanoglu E, Baumhueter S, Bostian KA, Brady L, Browne LJ, Calvin JT, Day GJ, Breckenridge N, Dunlea S, Eynon BP, Furness LM, Ferng J, Fielden MR, Fujimoto SY, Gong L, Hu C, Idury R, Judo MS, Kolaja KL, Lee MD, McSorley C, Minor JM, Nair RV, Natsoulis G, Nguyen P, Nicholson SM, Pham H, Roter AH, Sun D, Tan S, Thode S, Tolley AM, Vladimirova A, Yang J, Zhou Z, Jarnagin K.

J Biotechnol. 2005 Sep 29;119(3):219-44.


Classification of a large microarray data set: algorithm comparison and analysis of drug signatures.

Natsoulis G, El Ghaoui L, Lanckriet GR, Tolley AM, Leroy F, Dunlea S, Eynon BP, Pearson CI, Tugendreich S, Jarnagin K.

Genome Res. 2005 May;15(5):724-36.


Molecular basis for fungal selectivity of novel antimitotic compounds.

Lila T, Renau TE, Wilson L, Philips J, Natsoulis G, Cope MJ, Watkins WJ, Buysse J.

Antimicrob Agents Chemother. 2003 Jul;47(7):2273-82.


Adeno-associated virus Rep proteins target DNA sequences to a unique locus in the human genome.

Surosky RT, Urabe M, Godwin SG, McQuiston SA, Kurtzman GJ, Ozawa K, Natsoulis G.

J Virol. 1997 Oct;71(10):7951-9.


Therapeutic effect of Gag-nuclease fusion protein on retrovirus-infected cell cultures.

Schumann G, Qin L, Rein A, Natsoulis G, Boeke JD.

J Virol. 1996 Jul;70(7):4329-37.


Targeting foreign proteins to human immunodeficiency virus particles via fusion with Vpr and Vpx.

Wu X, Liu H, Xiao H, Kim J, Seshaiah P, Natsoulis G, Boeke JD, Hahn BH, Kappes JC.

J Virol. 1995 Jun;69(6):3389-98.


Targeting of a nuclease to murine leukemia virus capsids inhibits viral multiplication.

Natsoulis G, Seshaiah P, Federspiel MJ, Rein A, Hughes SH, Boeke JD.

Proc Natl Acad Sci U S A. 1995 Jan 17;92(2):364-8.


SPT10 and SPT21 are required for transcription of particular histone genes in Saccharomyces cerevisiae.

Dollard C, Ricupero-Hovasse SL, Natsoulis G, Boeke JD, Winston F.

Mol Cell Biol. 1994 Aug;14(8):5223-8.


The SPT10 and SPT21 genes of Saccharomyces cerevisiae.

Natsoulis G, Winston F, Boeke JD.

Genetics. 1994 Jan;136(1):93-105.


Hotspots for unselected Ty1 transposition events on yeast chromosome III are near tRNA genes and LTR sequences.

Ji H, Moore DP, Blomberg MA, Braiterman LT, Voytas DF, Natsoulis G, Boeke JD.

Cell. 1993 Jun 4;73(5):1007-18.


New antiviral strategy using capsid-nuclease fusion proteins.

Natsoulis G, Boeke JD.

Nature. 1991 Aug 15;352(6336):632-5.


Ty1 transposition in Saccharomyces cerevisiae is nonrandom.

Natsoulis G, Thomas W, Roghmann MC, Winston F, Boeke JD.

Genetics. 1989 Oct;123(2):269-79.


5-Fluoroorotic acid as a selective agent in yeast molecular genetics.

Boeke JD, Trueheart J, Natsoulis G, Fink GR.

Methods Enzymol. 1987;154:164-75.


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