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Items: 1 to 50 of 209

1.

Adaptation and memory in immune responses.

Natoli G, Ostuni R.

Nat Immunol. 2019 Jul;20(7):783-792. doi: 10.1038/s41590-019-0399-9. Epub 2019 Jun 18. Review.

PMID:
31213714
2.

Big data in IBD: a look into the future.

Olivera P, Danese S, Jay N, Natoli G, Peyrin-Biroulet L.

Nat Rev Gastroenterol Hepatol. 2019 May;16(5):312-321. doi: 10.1038/s41575-019-0102-5. Review.

PMID:
30659247
3.

Sex-Differences in the Pattern of Comorbidities, Functional Independence, and Mortality in Elderly Inpatients: Evidence from the RePoSI Register.

Corrao S, Argano C, Natoli G, Nobili A, Corazza GR, Mannucci PM, Perticone F; REPOSI Investigators.

J Clin Med. 2019 Jan 12;8(1). pii: E81. doi: 10.3390/jcm8010081.

4.

Control of inducible gene expression links cohesin to hematopoietic progenitor self-renewal and differentiation.

Cuartero S, Weiss FD, Dharmalingam G, Guo Y, Ing-Simmons E, Masella S, Robles-Rebollo I, Xiao X, Wang YF, Barozzi I, Djeghloul D, Amano MT, Niskanen H, Petretto E, Dowell RD, Tachibana K, Kaikkonen MU, Nasmyth KA, Lenhard B, Natoli G, Fisher AG, Merkenschlager M.

Nat Immunol. 2018 Sep;19(9):932-941. doi: 10.1038/s41590-018-0184-1. Epub 2018 Aug 20.

5.

A novel flash glucose monitoring system in patients with diabetes mellitus type 1 and 2: which are the pieces of evidence for payer decision-makers?

Corrao S, Nativo B, Natoli G, Lo Monaco M, Perticone F.

Intern Emerg Med. 2018 Sep;13(6):947-949. doi: 10.1007/s11739-018-1855-5. Epub 2018 May 8.

PMID:
29740729
6.

Sustained activation of detoxification pathways promotes liver carcinogenesis in response to chronic bile acid-mediated damage.

Collino A, Termanini A, Nicoli P, Diaferia G, Polletti S, Recordati C, Castiglioni V, Caruso D, Mitro N, Natoli G, Ghisletti S.

PLoS Genet. 2018 May 7;14(5):e1007380. doi: 10.1371/journal.pgen.1007380. eCollection 2018 May.

7.

Disability, and not diabetes, is a strong predictor of mortality in oldest old patients hospitalized with pneumonia.

Corrao S, Argano C, Natoli G, Nobili A, Corazza GR, Mannucci PM, Perticone F; REPOSI Investigators.

Eur J Intern Med. 2018 Aug;54:53-59. doi: 10.1016/j.ejim.2018.04.012. Epub 2018 May 1.

PMID:
29728312
8.

Co-optation of Tandem DNA Repeats for the Maintenance of Mesenchymal Identity.

Balestrieri C, Alfarano G, Milan M, Tosi V, Prosperini E, Nicoli P, Palamidessi A, Scita G, Diaferia GR, Natoli G.

Cell. 2018 May 17;173(5):1150-1164.e14. doi: 10.1016/j.cell.2018.03.081. Epub 2018 Apr 26.

9.

PARP14 Controls the Nuclear Accumulation of a Subset of Type I IFN-Inducible Proteins.

Caprara G, Prosperini E, Piccolo V, Sigismondo G, Melacarne A, Cuomo A, Boothby M, Rescigno M, Bonaldi T, Natoli G.

J Immunol. 2018 Apr 1;200(7):2439-2454. doi: 10.4049/jimmunol.1701117. Epub 2018 Mar 2.

10.

Housekeeping and tissue-specific cis-regulatory elements: Recipes for specificity and recipes for activity.

Russo M, Natoli G, Ghisletti S.

Transcription. 2018;9(3):177-181. doi: 10.1080/21541264.2017.1378158. Epub 2017 Nov 7.

11.

TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.

Montagner S, Leoni C, Emming S, Della Chiara G, Balestrieri C, Barozzi I, Piccolo V, Togher S, Ko M, Rao A, Natoli G, Monticelli S.

Cell Rep. 2017 Aug 15;20(7):1744. doi: 10.1016/j.celrep.2017.08.011. No abstract available.

12.

Transcriptional determination and functional specificity of myeloid cells: making sense of diversity.

Monticelli S, Natoli G.

Nat Rev Immunol. 2017 Oct;17(10):595-607. doi: 10.1038/nri.2017.51. Epub 2017 Jun 5. Review.

PMID:
28580958
13.

Understanding Spontaneous Conversion: The Case of the Ly6C- Monocyte.

Polletti S, Natoli G.

Immunity. 2017 May 16;46(5):764-766. doi: 10.1016/j.immuni.2017.04.010.

14.

The case of homeopathy, "how to search PubMed" may be a first step.

Corrao S, Natoli G.

Eur J Intern Med. 2017 Jun;41:e8-e9. doi: 10.1016/j.ejim.2017.04.006. Epub 2017 Apr 20. No abstract available.

PMID:
28433480
15.

Opposing macrophage polarization programs show extensive epigenomic and transcriptional cross-talk.

Piccolo V, Curina A, Genua M, Ghisletti S, Simonatto M, Sabò A, Amati B, Ostuni R, Natoli G.

Nat Immunol. 2017 May;18(5):530-540. doi: 10.1038/ni.3710. Epub 2017 Mar 13.

16.

High constitutive activity of a broad panel of housekeeping and tissue-specific cis-regulatory elements depends on a subset of ETS proteins.

Curina A, Termanini A, Barozzi I, Prosperini E, Simonatto M, Polletti S, Silvola A, Soldi M, Austenaa L, Bonaldi T, Ghisletti S, Natoli G.

Genes Dev. 2017 Feb 15;31(4):399-412. doi: 10.1101/gad.293134.116. Epub 2017 Mar 8.

17.

A shortcut for early macrophage recruitment into tumors by activated oncogenes.

Austenaa L, Natoli G.

Genes Dev. 2017 Feb 1;31(3):223-225. doi: 10.1101/gad.296905.117.

18.

Mutual epithelium-macrophage dependency in liver carcinogenesis mediated by ST18.

Ravà M, D'Andrea A, Doni M, Kress TR, Ostuni R, Bianchi V, Morelli MJ, Collino A, Ghisletti S, Nicoli P, Recordati C, Iascone M, Sonzogni A, D'Antiga L, Shukla R, Faulkner GJ, Natoli G, Campaner S, Amati B.

Hepatology. 2017 May;65(5):1708-1719. doi: 10.1002/hep.28942. Epub 2016 Dec 30.

19.

Clinical Severity, Age, and Sex Overcome Cardiometabolic Morbidities but Not Stroke as Predictors of Mortality in Elderly Inpatients: Data From the REgistro POliterapie Società Italiana di Medicina Interna Registry.

Corrao S, Marengoni A, Natoli G, Nobili A, Mannucci P, Perticone F.

J Am Geriatr Soc. 2016 Aug;64(8):1737-9. doi: 10.1111/jgs.14197. Epub 2016 Jul 26. No abstract available.

PMID:
27458820
20.

Specificity and Function of IRF Family Transcription Factors: Insights from Genomics.

Mancino A, Natoli G.

J Interferon Cytokine Res. 2016 Jul;36(7):462-9. doi: 10.1089/jir.2016.0004. Review.

PMID:
27379868
21.

Prevalence and distribution of oral mucosal non-malignant lesions in the western Sicilian population.

Tortorici S, Corrao S, Natoli G, Difalco P.

Minerva Stomatol. 2016 Aug;65(4):191-206.

PMID:
27374359
22.

In Vivo Genetic Screens of Patient-Derived Tumors Revealed Unexpected Frailty of the Transformed Phenotype.

Bossi D, Cicalese A, Dellino GI, Luzi L, Riva L, D'Alesio C, Diaferia GR, Carugo A, Cavallaro E, Piccioni R, Barberis M, Mazzarol G, Testori A, Punzi S, Pallavicini I, Tosti G, Giacó L, Melloni G, Heffernan TP, Natoli G, Draetta GF, Minucci S, Pelicci P, Lanfrancone L.

Cancer Discov. 2016 Jun;6(6):650-63. doi: 10.1158/2159-8290.CD-15-1200. Epub 2016 May 13.

23.

TET2 Regulates Mast Cell Differentiation and Proliferation through Catalytic and Non-catalytic Activities.

Montagner S, Leoni C, Emming S, Della Chiara G, Balestrieri C, Barozzi I, Piccolo V, Togher S, Ko M, Rao A, Natoli G, Monticelli S.

Cell Rep. 2016 May 17;15(7):1566-1579. doi: 10.1016/j.celrep.2016.04.044. Epub 2016 May 5. Erratum in: Cell Rep. 2017 Aug 15;20(7):1744.

24.

Trained immunity: A program of innate immune memory in health and disease.

Netea MG, Joosten LA, Latz E, Mills KH, Natoli G, Stunnenberg HG, O'Neill LA, Xavier RJ.

Science. 2016 Apr 22;352(6284):aaf1098. doi: 10.1126/science.aaf1098. Epub 2016 Apr 21. Review.

25.

Epigenetic regulation of neutrophil development and function.

Ostuni R, Natoli G, Cassatella MA, Tamassia N.

Semin Immunol. 2016 Apr;28(2):83-93. doi: 10.1016/j.smim.2016.04.002. Epub 2016 Apr 12. Review.

PMID:
27084194
26.

From the Beauty of Genomic Landscapes to the Strength of Transcriptional Mechanisms.

Natoli G.

Cell. 2016 Mar 24;165(1):18-19. doi: 10.1016/j.cell.2016.03.011.

27.

Dissection of transcriptional and cis-regulatory control of differentiation in human pancreatic cancer.

Diaferia GR, Balestrieri C, Prosperini E, Nicoli P, Spaggiari P, Zerbi A, Natoli G.

EMBO J. 2016 Mar 15;35(6):595-617. doi: 10.15252/embj.201592404. Epub 2016 Jan 14.

28.

Molecular control of activation and priming in macrophages.

Glass CK, Natoli G.

Nat Immunol. 2016 Jan;17(1):26-33. doi: 10.1038/ni.3306. Review.

29.

Transcription of Mammalian cis-Regulatory Elements Is Restrained by Actively Enforced Early Termination.

Austenaa LM, Barozzi I, Simonatto M, Masella S, Della Chiara G, Ghisletti S, Curina A, de Wit E, Bouwman BA, de Pretis S, Piccolo V, Termanini A, Prosperini E, Pelizzola M, de Laat W, Natoli G.

Mol Cell. 2015 Nov 5;60(3):460-74. doi: 10.1016/j.molcel.2015.09.018. Epub 2015 Oct 22.

30.

CAGE profiling of ncRNAs in hepatocellular carcinoma reveals widespread activation of retroviral LTR promoters in virus-induced tumors.

Hashimoto K, Suzuki AM, Dos Santos A, Desterke C, Collino A, Ghisletti S, Braun E, Bonetti A, Fort A, Qin XY, Radaelli E, Kaczkowski B, Forrest AR, Kojima S, Samuel D, Natoli G, Buendia MA, Faivre J, Carninci P.

Genome Res. 2015 Dec;25(12):1812-24. doi: 10.1101/gr.191031.115. Epub 2015 Oct 28.

31.

Corrigendum: Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency.

Iannelli F, Collino A, Sinha S, Radaelli E, Nicoli P, D'Antiga L, Sonzogni A, Faivre J, Buendia MA, Sturm E, Thompson RJ, Knisely AS, Natoli G, Ghisletti S, Ciccarelli FD.

Nat Commun. 2015 Jul 2;6:7456. doi: 10.1038/ncomms8456. No abstract available.

PMID:
26135945
32.

When antimicrobial peptides hit the wrong target: a novel link between tumour macrophages and cancer stem cells.

Diaferia GR, Natoli G.

Gut. 2015 Dec;64(12):1841-2. doi: 10.1136/gutjnl-2015-309605. Epub 2015 May 12. No abstract available.

PMID:
25966994
33.

Macrophages and cancer: from mechanisms to therapeutic implications.

Ostuni R, Kratochvill F, Murray PJ, Natoli G.

Trends Immunol. 2015 Apr;36(4):229-39. doi: 10.1016/j.it.2015.02.004. Epub 2015 Mar 11. Review.

PMID:
25770924
34.

A dual cis-regulatory code links IRF8 to constitutive and inducible gene expression in macrophages.

Mancino A, Termanini A, Barozzi I, Ghisletti S, Ostuni R, Prosperini E, Ozato K, Natoli G.

Genes Dev. 2015 Feb 15;29(4):394-408. doi: 10.1101/gad.257592.114. Epub 2015 Jan 30.

35.

Chromatin remodelling and autocrine TNFα are required for optimal interleukin-6 expression in activated human neutrophils.

Zimmermann M, Aguilera FB, Castellucci M, Rossato M, Costa S, Lunardi C, Ostuni R, Girolomoni G, Natoli G, Bazzoni F, Tamassia N, Cassatella MA.

Nat Commun. 2015 Jan 23;6:6061. doi: 10.1038/ncomms7061.

PMID:
25616107
36.

Transcriptional control of inflammatory responses.

Smale ST, Natoli G.

Cold Spring Harb Perspect Biol. 2014 Sep 11;6(11):a016261. doi: 10.1101/cshperspect.a016261. Review.

37.

Two functionally distinct subsets of mast cells discriminated By IL-2-independent CD25 activities.

Deho' L, Leoni C, Brodie TM, Montagner S, De Simone M, Polletti S, Barozzi I, Natoli G, Monticelli S.

J Immunol. 2014 Sep 1;193(5):2196-206. doi: 10.4049/jimmunol.1400516. Epub 2014 Jul 25.

38.

Macrophage activation and polarization: nomenclature and experimental guidelines.

Murray PJ, Allen JE, Biswas SK, Fisher EA, Gilroy DW, Goerdt S, Gordon S, Hamilton JA, Ivashkiv LB, Lawrence T, Locati M, Mantovani A, Martinez FO, Mege JL, Mosser DM, Natoli G, Saeij JP, Schultze JL, Shirey KA, Sica A, Suttles J, Udalova I, van Ginderachter JA, Vogel SN, Wynn TA.

Immunity. 2014 Jul 17;41(1):14-20. doi: 10.1016/j.immuni.2014.06.008.

39.

Massive gene amplification drives paediatric hepatocellular carcinoma caused by bile salt export pump deficiency.

Iannelli F, Collino A, Sinha S, Radaelli E, Nicoli P, D'Antiga L, Sonzogni A, Faivre J, Buendia MA, Sturm E, Thompson RJ, Knisely AS, Natoli G, Ghisletti S, Ciccarelli FD.

Nat Commun. 2014 May 13;5:3850. doi: 10.1038/ncomms4850. Erratum in: Nat Commun. 2015;6:7456.

PMID:
24819516
40.

Coregulation of transcription factor binding and nucleosome occupancy through DNA features of mammalian enhancers.

Barozzi I, Simonatto M, Bonifacio S, Yang L, Rohs R, Ghisletti S, Natoli G.

Mol Cell. 2014 Jun 5;54(5):844-857. doi: 10.1016/j.molcel.2014.04.006. Epub 2014 May 8.

41.

Macrophage activation: glancing into diversity.

Natoli G, Monticelli S.

Immunity. 2014 Feb 20;40(2):175-7. doi: 10.1016/j.immuni.2014.01.004.

42.

Chromatin contributions to the regulation of innate immunity.

Smale ST, Tarakhovsky A, Natoli G.

Annu Rev Immunol. 2014;32:489-511. doi: 10.1146/annurev-immunol-031210-101303. Epub 2014 Feb 6. Review.

PMID:
24555473
43.

Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis.

Angelucci F, Saccoccia F, Ardini M, Boumis G, Brunori M, Di Leandro L, Ippoliti R, Miele AE, Natoli G, Scotti S, Bellelli A.

J Mol Biol. 2013 Nov 15;425(22):4556-68. doi: 10.1016/j.jmb.2013.09.002. Epub 2013 Sep 8.

PMID:
24021815
44.

Lineages, cell types and functional states: a genomic view.

Ostuni R, Natoli G.

Curr Opin Cell Biol. 2013 Dec;25(6):759-64. doi: 10.1016/j.ceb.2013.07.006. Epub 2013 Jul 29. Review.

PMID:
23906851
45.

Short-term memory of danger signals and environmental stimuli in immune cells.

Monticelli S, Natoli G.

Nat Immunol. 2013 Aug;14(8):777-84. doi: 10.1038/ni.2636.

PMID:
23867934
46.

Functional genomics of the inflammatory response: where are we now?

Simonatto M, Natoli G.

Brief Funct Genomics. 2013 Nov;12(6):483-8. doi: 10.1093/bfgp/elt023. Epub 2013 Jun 28. Review.

PMID:
23814131
47.

Epirubicin and docetaxel as first-line treatment for hormonal receptor positive metastatic breast cancer: the predictive value of luminal subtype: a retrospective cohort analysis.

Nelli F, Natoli G, Moscetti L, Massari A, D'Auria G, Fabbri MA, Frittelli P, Ruggeri EM.

J Chemother. 2013 Apr;25(2):112-8. doi: 10.1179/1973947812Y.0000000059.

PMID:
23684359
48.

Deciphering cis-regulatory control in inflammatory cells.

Ghisletti S, Natoli G.

Philos Trans R Soc Lond B Biol Sci. 2013 May 6;368(1620):20120370. doi: 10.1098/rstb.2012.0370. Print 2013. Review.

49.

Non-coding transcription at cis-regulatory elements: computational and experimental approaches.

Simonatto M, Barozzi I, Natoli G.

Methods. 2013 Sep 1;63(1):66-75. doi: 10.1016/j.ymeth.2013.03.021. Epub 2013 Mar 29.

PMID:
23542771
50.

Endogenous retrotransposition activates oncogenic pathways in hepatocellular carcinoma.

Shukla R, Upton KR, Muñoz-Lopez M, Gerhardt DJ, Fisher ME, Nguyen T, Brennan PM, Baillie JK, Collino A, Ghisletti S, Sinha S, Iannelli F, Radaelli E, Dos Santos A, Rapoud D, Guettier C, Samuel D, Natoli G, Carninci P, Ciccarelli FD, Garcia-Perez JL, Faivre J, Faulkner GJ.

Cell. 2013 Mar 28;153(1):101-11. doi: 10.1016/j.cell.2013.02.032.

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