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Items: 1 to 50 of 175

1.

High frequency of CD74 expression in lymphomas: implications for targeted therapy using a novel anti-CD74-drug conjugate.

Zhao S, Molina A, Yu A, Hanson J, Cheung H, Li X, Natkunam Y.

J Pathol Clin Res. 2018 Sep 7. doi: 10.1002/cjp2.114. [Epub ahead of print]

2.

Granulysin, a novel marker for extranodal NK/T cell lymphoma, nasal type.

Lo Bello G, Akarca AU, Ambrosio MR, Agostinelli C, Molina-Kirsch H, Ramsay A, Rodriguez-Justo M, Pugh M, Zhao S, DeLisser M, Sabattini E, Dojcinov S, Pileri SA, Natkunam Y, Leoncini L, Marafioti T.

Virchows Arch. 2018 Aug 27. doi: 10.1007/s00428-018-2434-x. [Epub ahead of print]

PMID:
30151671
3.

Immunodeficiency-associated lymphoproliferative disorders: time for reappraisal?

Natkunam Y, Gratzinger D, Chadburn A, Goodlad JR, Chan JKC, Said J, Jaffe ES, de Jong D.

Blood. 2018 Nov 1;132(18):1871-1878. doi: 10.1182/blood-2018-04-842559. Epub 2018 Aug 6. Review.

PMID:
30082493
4.

Immunohistochemistry for PAX7 is a useful confirmatory marker for Ewing sarcoma in decalcified bone marrow core biopsy specimens.

Fernandez-Pol S, van de Rijn M, Natkunam Y, Charville GW.

Virchows Arch. 2018 Jul 17. doi: 10.1007/s00428-018-2410-5. [Epub ahead of print]

PMID:
30014288
5.

FOXP3-positive T-cell lymphomas in non-HTLV1 carriers include ALK-negative anaplastic large cell lymphoma: expanding the spectrum of T-cell lymphomas with regulatory phenotype.

Ferreira CR, Zhao S, Sahoo MK, Pinsky B, Weber J, Lage LAPC, Pereira J, Zerbini MCN, Natkunam Y.

Hum Pathol. 2018 Oct;80:138-144. doi: 10.1016/j.humpath.2018.06.001. Epub 2018 Jun 10.

PMID:
29898383
6.

Lmo2 expression defines tumor cell identity during T-cell leukemogenesis.

García-Ramírez I, Bhatia S, Rodríguez-Hernández G, González-Herrero I, Walter C, González de Tena-Dávila S, Parvin S, Haas O, Woessmann W, Stanulla M, Schrappe M, Dugas M, Natkunam Y, Orfao A, Domínguez V, Pintado B, Blanco O, Alonso-López D, De Las Rivas J, Martín-Lorenzo A, Jiménez R, García Criado FJ, García Cenador MB, Lossos IS, Vicente-Dueñas C, Borkhardt A, Hauer J, Sánchez-García I.

EMBO J. 2018 Jul 13;37(14). pii: e98783. doi: 10.15252/embj.201798783. Epub 2018 Jun 7.

7.

Defining the elusive boundaries of chronic active Epstein-Barr virus infection.

Fernandez-Pol S, Silva O, Natkunam Y.

Haematologica. 2018 Jun;103(6):924-927. doi: 10.3324/haematol.2018.193714. No abstract available.

8.

Expression of the transcription factor ZBTB46 distinguishes human histiocytic disorders of classical dendritic cell origin.

Satpathy AT, Brown RA, Gomulia E, Briseño CG, Mumbach MR, Pan Z, Murphy KM, Natkunam Y, Chang HY, Kim J.

Mod Pathol. 2018 Sep;31(9):1479-1486. doi: 10.1038/s41379-018-0052-4. Epub 2018 May 9.

9.

KLHL6 Is Preferentially Expressed in Germinal Center-Derived B-Cell Lymphomas.

Kunder CA, Roncador G, Advani RH, Gualco G, Bacchi CE, Sabile JM, Lossos IS, Nie K, Tibshirani RJ, Green MR, Alizadeh AA, Natkunam Y.

Am J Clin Pathol. 2017 Nov 20;148(6):465-476. doi: 10.1093/ajcp/aqx099.

PMID:
29140403
10.

Programmed death-1 ligands PD-L1 and PD-L2 show distinctive and restricted patterns of expression in lymphoma subtypes.

Panjwani PK, Charu V, DeLisser M, Molina-Kirsch H, Natkunam Y, Zhao S.

Hum Pathol. 2018 Jan;71:91-99. doi: 10.1016/j.humpath.2017.10.029. Epub 2017 Nov 6.

PMID:
29122656
11.

Immunohistochemical Profile of MYC Protein in Pediatric Small Round Blue Cell Tumors.

Chisholm KM, Krishnan C, Heerema-McKenney A, Natkunam Y.

Pediatr Dev Pathol. 2017 Jun;20(3):213-223. doi: 10.1177/1093526616689642. Epub 2017 Feb 10.

PMID:
28521631
12.

Unifying mechanism for different fibrotic diseases.

Wernig G, Chen SY, Cui L, Van Neste C, Tsai JM, Kambham N, Vogel H, Natkunam Y, Gilliland DG, Nolan G, Weissman IL.

Proc Natl Acad Sci U S A. 2017 May 2;114(18):4757-4762. doi: 10.1073/pnas.1621375114. Epub 2017 Apr 19.

13.

Prognostic relevance of CD163 and CD8 combined with EZH2 and gain of chromosome 18 in follicular lymphoma: a study by the Lunenburg Lymphoma Biomarker Consortium.

Stevens WBC, Mendeville M, Redd R, Clear AJ, Bladergroen R, Calaminici M, Rosenwald A, Hoster E, Hiddemann W, Gaulard P, Xerri L, Salles G, Klapper W, Pfreundschuh M, Jack A, Gascoyne RD, Natkunam Y, Advani R, Kimby E, Sander B, Sehn LH, Hagenbeek A, Raemaekers J, Gribben J, Kersten MJ, Ylstra B, Weller E, de Jong D.

Haematologica. 2017 Aug;102(8):1413-1423. doi: 10.3324/haematol.2017.165415. Epub 2017 Apr 14.

14.

B-Cell and Classical Hodgkin Lymphomas Associated With Immunodeficiency: 2015 SH/EAHP Workshop Report-Part 2.

de Jong D, Roemer MG, Chan JK, Goodlad J, Gratzinger D, Chadburn A, Jaffe ES, Said J, Natkunam Y.

Am J Clin Pathol. 2017 Feb 1;147(2):153-170. doi: 10.1093/ajcp/aqw216.

PMID:
28395108
15.

EBV-Positive B-Cell Proliferations of Varied Malignant Potential: 2015 SH/EAHP Workshop Report-Part 1.

Natkunam Y, Goodlad JR, Chadburn A, de Jong D, Gratzinger D, Chan JK, Said J, Jaffe ES.

Am J Clin Pathol. 2017 Feb 1;147(2):129-152. doi: 10.1093/ajcp/aqw214.

PMID:
28395107
16.

Primary/Congenital Immunodeficiency: 2015 SH/EAHP Workshop Report-Part 5.

Gratzinger D, Jaffe ES, Chadburn A, Chan JK, de Jong D, Goodlad JR, Said J, Natkunam Y.

Am J Clin Pathol. 2017 Feb 1;147(2):204-216. doi: 10.1093/ajcp/aqw215.

PMID:
28395106
17.

T- and NK-Cell Lymphomas and Systemic Lymphoproliferative Disorders and the Immunodeficiency Setting: 2015 SH/EAHP Workshop Report-Part 4.

Gratzinger D, de Jong D, Jaffe ES, Chadburn A, Chan JK, Goodlad JR, Said J, Natkunam Y.

Am J Clin Pathol. 2017 Feb 1;147(2):188-203. doi: 10.1093/ajcp/aqw213.

PMID:
28395105
18.

HHV8/KSHV-Positive Lymphoproliferative Disorders and the Spectrum of Plasmablastic and Plasma Cell Neoplasms: 2015 SH/EAHP Workshop Report-Part 3.

Chadburn A, Said J, Gratzinger D, Chan JK, de Jong D, Jaffe ES, Natkunam Y, Goodlad JR.

Am J Clin Pathol. 2017 Feb 1;147(2):171-187. doi: 10.1093/ajcp/aqw218.

PMID:
28395104
19.

Immunodeficiency and Dysregulation: Report of the 2015 Workshop of the Society for Hematopathology/European Association for Haematopathology.

Natkunam Y, Gratzinger D, de Jong D, Chadburn A, Goodlad JR, Chan JK, Said J, Jaffe ES.

Am J Clin Pathol. 2017 Feb 1;147(2):124-128. doi: 10.1093/ajcp/aqw200. No abstract available.

PMID:
28395103
20.

Molecular impact of selective NFKB1 and NFKB2 signaling on DLBCL phenotype.

Guo X, Koff JL, Moffitt AB, Cinar M, Ramachandiran S, Chen Z, Switchenko JM, Mosunjac M, Neill SG, Mann KP, Bagirov M, Du Y, Natkunam Y, Khoury HJ, Rossi MR, Harris W, Flowers CR, Lossos IS, Boise LH, Dave SS, Kowalski J, Bernal-Mizrachi L.

Oncogene. 2017 Jul 20;36(29):4224-4232. doi: 10.1038/onc.2017.90. Epub 2017 Apr 3.

PMID:
28368397
21.

Epstein-Barr virus-positive follicular lymphoma.

Mackrides N, Campuzano-Zuluaga G, Maque-Acosta Y, Moul A, Hijazi N, Ikpatt FO, Levy R, Verdun RE, Kunkalla K, Natkunam Y, Lossos IS, Vega F, Chapman J.

Mod Pathol. 2017 Apr;30(4):519-529. doi: 10.1038/modpathol.2016.214. Epub 2016 Dec 16.

22.

Classical Hodgkin Lymphoma with Reduced β2M/MHC Class I Expression Is Associated with Inferior Outcome Independent of 9p24.1 Status.

Roemer MG, Advani RH, Redd RA, Pinkus GS, Natkunam Y, Ligon AH, Connelly CF, Pak CJ, Carey CD, Daadi SE, Chapuy B, de Jong D, Hoppe RT, Neuberg DS, Shipp MA, Rodig SJ.

Cancer Immunol Res. 2016 Nov;4(11):910-916. Epub 2016 Oct 13.

23.

Pathophysiological significance and therapeutic targeting of germinal center kinase in diffuse large B-cell lymphoma.

Matthews JM, Bhatt S, Patricelli MP, Nomanbhoy TK, Jiang X, Natkunam Y, Gentles AJ, Martinez E, Zhu D, Chapman JR, Cortizas E, Shyam R, Chinichian S, Advani R, Tan L, Zhang J, Choi HG, Tibshirani R, Buhrlage SJ, Gratzinger D, Verdun R, Gray NS, Lossos IS.

Blood. 2016 Jul 14;128(2):239-48. doi: 10.1182/blood-2016-02-696856. Epub 2016 May 5.

24.

PD-L1 and PD-L2 Genetic Alterations Define Classical Hodgkin Lymphoma and Predict Outcome.

Roemer MG, Advani RH, Ligon AH, Natkunam Y, Redd RA, Homer H, Connelly CF, Sun HH, Daadi SE, Freeman GJ, Armand P, Chapuy B, de Jong D, Hoppe RT, Neuberg DS, Rodig SJ, Shipp MA.

J Clin Oncol. 2016 Aug 10;34(23):2690-7. doi: 10.1200/JCO.2016.66.4482. Epub 2016 Apr 11.

25.

Isolated Follicles Enriched for Centroblasts and Lacking t(14;18)/BCL2 in Lymphoid Tissue: Diagnostic and Clinical Implications.

Nybakken GE, Bala R, Gratzinger D, Jones CD, Zehnder JL, Bangs CD, Cherry A, Warnke RA, Natkunam Y.

PLoS One. 2016 Mar 18;11(3):e0151735. doi: 10.1371/journal.pone.0151735. eCollection 2016.

26.

Myeloid Cell Nuclear Differentiation Antigen (MNDA) Expression Distinguishes Extramedullary Presentations of Myeloid Leukemia From Blastic Plasmacytoid Dendritic Cell Neoplasm.

Johnson RC, Kim J, Natkunam Y, Sundram U, Freud AG, Gammon B, Cascio MJ.

Am J Surg Pathol. 2016 Apr;40(4):502-9. doi: 10.1097/PAS.0000000000000595.

PMID:
26796502
27.

An analysis of MYC and EBV in diffuse large B-cell lymphomas associated with angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma not otherwise specified.

Hoffmann JC, Chisholm KM, Cherry A, Chen J, Arber DA, Natkunam Y, Warnke RA, Ohgami RS.

Hum Pathol. 2016 Feb;48:9-17. doi: 10.1016/j.humpath.2015.09.033. Epub 2015 Oct 23.

PMID:
26772393
28.

The Epstein-Barr Virus (EBV) in T Cell and NK Cell Lymphomas: Time for a Reassessment.

Gru AA, Haverkos BH, Freud AG, Hastings J, Nowacki NB, Barrionuevo C, Vigil CE, Rochford R, Natkunam Y, Baiocchi RA, Porcu P.

Curr Hematol Malig Rep. 2015 Dec;10(4):456-67. doi: 10.1007/s11899-015-0292-z. Review.

29.

Immunoarchitectural patterns of progressive transformation of germinal centers with and without nodular lymphocyte-predominant Hodgkin lymphoma.

Hartmann S, Winkelmann R, Metcalf RA, Treetipsatit J, Warnke RA, Natkunam Y, Hansmann ML.

Hum Pathol. 2015 Nov;46(11):1655-61. doi: 10.1016/j.humpath.2015.07.006. Epub 2015 Jul 21.

PMID:
26410017
30.

Indolent T-lymphoblastic proliferation: a name with specific meaning.

Ohgami RS, Natkunam Y, Warnke RA.

Hum Pathol. 2015 Nov;46(11):1785-6. doi: 10.1016/j.humpath.2015.07.026. Epub 2015 Aug 11. No abstract available.

PMID:
26363525
31.

A single-institution retrospective analysis of outcomes for stage I-II primary mediastinal large B-cell lymphoma treated with immunochemotherapy with or without radiotherapy.

Binkley MS, Hiniker SM, Wu S, Natkunam Y, Mittra ES, Advani RH, Hoppe RT.

Leuk Lymphoma. 2016;57(3):604-8. doi: 10.3109/10428194.2015.1067700. Epub 2015 Aug 28.

PMID:
26159046
32.

Management of nodular lymphocyte predominant Hodgkin lymphoma in the modern era.

King MT, Donaldson SS, Link MP, Natkunam Y, Advani RH, Hoppe RT.

Int J Radiat Oncol Biol Phys. 2015 May 1;92(1):67-75. doi: 10.1016/j.ijrobp.2015.02.001.

PMID:
25863755
33.

Expression profiles of MYC protein and MYC gene rearrangement in lymphomas.

Chisholm KM, Bangs CD, Bacchi CE, Molina-Kirsch H, Cherry A, Natkunam Y.

Am J Surg Pathol. 2015 Mar;39(3):294-303. doi: 10.1097/PAS.0000000000000365.

PMID:
25581730
34.

Large B-cell lymphoma with T-cell-rich background and nodules lacking follicular dendritic cell meshworks: description of an insufficiently recognized variant.

Treetipsatit J, Metcalf RA, Warnke RA, Natkunam Y.

Hum Pathol. 2015 Jan;46(1):74-83. doi: 10.1016/j.humpath.2014.09.009. Epub 2014 Oct 8.

PMID:
25456392
35.

Chromosome instability in diffuse large B cell lymphomas is suppressed by activation of the noncanonical NF-κB pathway.

Ramachandiran S, Adon A, Guo X, Wang Y, Wang H, Chen Z, Kowalski J, Sunay UR, Young AN, Brown T, Mar JC, Du Y, Fu H, Mann KP, Natkunam Y, Boise LH, Saavedra HI, Lossos IS, Bernal-Mizrachi L.

Int J Cancer. 2015 May 15;136(10):2341-51. doi: 10.1002/ijc.29301. Epub 2014 Nov 11.

36.

Kappa and lambda light chain mRNA in situ hybridization compared to flow cytometry and immunohistochemistry in B cell lymphomas.

Rimsza LM, Day WA, McGinn S, Pedata A, Natkunam Y, Warnke R, Cook JR, Marafioti T, Grogan TM.

Diagn Pathol. 2014 Jul 21;9:144. doi: 10.1186/1746-1596-9-144.

37.

Large B-cell lymphomas poor in B cells and rich in PD-1+ T cells can mimic T-cell lymphomas.

Ohgami RS, Zhao S, Natkunam Y.

Am J Clin Pathol. 2014 Aug;142(2):150-6. doi: 10.1309/AJCPFJWKQ6GTVQE6.

PMID:
25015854
38.

Myeloid cell nuclear differentiation antigen is expressed in a subset of marginal zone lymphomas and is useful in the differential diagnosis with follicular lymphoma.

Metcalf RA, Monabati A, Vyas M, Roncador G, Gualco G, Bacchi CE, Younes SF, Natkunam Y, Freud AG.

Hum Pathol. 2014 Aug;45(8):1730-6. doi: 10.1016/j.humpath.2014.04.004. Epub 2014 Apr 24.

PMID:
24925224
39.

Variable expression of B-cell transcription factors in reactive immunoblastic proliferations: a potential mimic of classical Hodgkin lymphoma.

Treetipsatit J, Rimzsa L, Grogan T, Warnke RA, Natkunam Y.

Am J Surg Pathol. 2014 Dec;38(12):1655-63. doi: 10.1097/PAS.0000000000000266.

PMID:
24921642
40.

Transient expression of Bcl6 is sufficient for oncogenic function and induction of mature B-cell lymphoma.

Green MR, Vicente-Dueñas C, Romero-Camarero I, Long Liu C, Dai B, González-Herrero I, García-Ramírez I, Alonso-Escudero E, Iqbal J, Chan WC, Campos-Sanchez E, Orfao A, Pintado B, Flores T, Blanco O, Jiménez R, Martínez-Climent JA, Criado FJ, Cenador MB, Zhao S, Natkunam Y, Lossos IS, Majeti R, Melnick A, Cobaleda C, Alizadeh AA, Sánchez-García I.

Nat Commun. 2014 Jun 2;5:3904. doi: 10.1038/ncomms4904.

41.

Use of CD137 ligand expression in the detection of small B-cell lymphomas involving the bone marrow.

Zhao S, Xing Y, Natkunam Y.

Hum Pathol. 2014 May;45(5):1024-30. doi: 10.1016/j.humpath.2013.12.019. Epub 2014 Jan 21.

PMID:
24746207
42.

Indolent T-lymphoblastic proliferation with disseminated multinodal involvement and partial CD33 expression.

Ohgami RS, Sendamarai AK, Atwater SK, Liedtke M, Fleming MD, Natkunam Y, Warnke RA.

Am J Surg Pathol. 2014 Sep;38(9):1298-304. doi: 10.1097/PAS.0000000000000197.

PMID:
24618611
43.

Multiplexed ion beam imaging of human breast tumors.

Angelo M, Bendall SC, Finck R, Hale MB, Hitzman C, Borowsky AD, Levenson RM, Lowe JB, Liu SD, Zhao S, Natkunam Y, Nolan GP.

Nat Med. 2014 Apr;20(4):436-42. doi: 10.1038/nm.3488. Epub 2014 Mar 2.

44.

LMO2 and BCL6 are associated with improved survival in primary central nervous system lymphoma.

Lossos C, Bayraktar S, Weinzierl E, Younes SF, Hosein PJ, Tibshirani RJ, Sutton Posthumus J, DeAngelis LM, Raizer J, Schiff D, Abrey L, Natkunam Y, Lossos IS.

Br J Haematol. 2014 Jun;165(5):640-8. doi: 10.1111/bjh.12801. Epub 2014 Feb 26. Review.

45.

Mature results of a phase II study of rituximab therapy for nodular lymphocyte-predominant Hodgkin lymphoma.

Advani RH, Horning SJ, Hoppe RT, Daadi S, Allen J, Natkunam Y, Bartlett NL.

J Clin Oncol. 2014 Mar 20;32(9):912-8. doi: 10.1200/JCO.2013.53.2069. Epub 2014 Feb 10.

PMID:
24516013
46.

LMO2 (LIM domain only 2) is expressed in a subset of acute myeloid leukaemia and correlates with normal karyotype.

Patel JL, Pournazari P, Haggstrom SJ, Kosari F, Shabani-Rad MT, Natkunam Y, Mansoor A.

Histopathology. 2014 Jan;64(2):226-33. doi: 10.1111/his.12242. Epub 2013 Nov 6.

PMID:
24330148
47.

Expression of the activating receptor, NKp46 (CD335), in human natural killer and T-cell neoplasia.

Freud AG, Zhao S, Wei S, Gitana GM, Molina-Kirsch HF, Atwater SK, Natkunam Y.

Am J Clin Pathol. 2013 Dec;140(6):853-66. doi: 10.1309/AJCPWGG69MCZOWMM.

PMID:
24225754
48.

FHIT, EGFR, and MSH2: possible etiopathologic, prognostic, and predictive role in non-small cell lung carcinoma in Egyptian patients.

Younes SF, Aiad HA, Asaad NY, Kandil MA, Natkunam Y, Mokhtar NM.

Appl Immunohistochem Mol Morphol. 2014 Apr;22(4):275-83. doi: 10.1097/PAI.0b013e3182988fa5.

PMID:
24185125
49.

CD30 targeting with brentuximab vedotin: a novel therapeutic approach to primary effusion lymphoma.

Bhatt S, Ashlock BM, Natkunam Y, Sujoy V, Chapman JR, Ramos JC, Mesri EA, Lossos IS.

Blood. 2013 Aug 15;122(7):1233-42. doi: 10.1182/blood-2013-01-481713. Epub 2013 Jul 9.

50.

LITAF, a BCL6 target gene, regulates autophagy in mature B-cell lymphomas.

Bertolo C, Roa S, Sagardoy A, Mena-Varas M, Robles EF, Martinez-Ferrandis JI, Sagaert X, Tousseyn T, Orta A, Lossos IS, Amar S, Natkunam Y, Briones J, Melnick A, Malumbres R, Martinez-Climent JA.

Br J Haematol. 2013 Sep;162(5):621-30. doi: 10.1111/bjh.12440. Epub 2013 Jun 25.

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