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Items: 1 to 50 of 742

1.

Engineering of a novel subnanomolar affinity fibronectin III domain binder targeting human programmed death-ligand 1.

Ramakrishnan S, Natarajan A, Chan CT, Panesar PS, Gambhir SS.

Protein Eng Des Sel. 2019 Oct 15. pii: gzz030. doi: 10.1093/protein/gzz030. [Epub ahead of print]

PMID:
31612217
2.

Evaluation of integrin αvβ6 cystine knot PET tracers to detect cancer and idiopathic pulmonary fibrosis.

Kimura RH, Wang L, Shen B, Huo L, Tummers W, Filipp FV, Guo HH, Haywood T, Abou-Elkacem L, Baratto L, Habte F, Devulapally R, Witney TH, Cheng Y, Tikole S, Chakraborti S, Nix J, Bonagura CA, Hatami N, Mooney JJ, Desai T, Turner S, Gaster RS, Otte A, Visser BC, Poultsides GA, Norton J, Park W, Stolowitz M, Lau K, Yang E, Natarajan A, Ilovich O, Srinivas S, Srinivasan A, Paulmurugan R, Willmann J, Chin FT, Cheng Z, Iagaru A, Li F, Gambhir SS.

Nat Commun. 2019 Oct 14;10(1):4673. doi: 10.1038/s41467-019-11863-w.

3.

Efficacy of Periconceptional High-Dose Folic Acid in Isolated Orofacial Cleft Prevention: A Systematic Review.

Jayarajan R, Natarajan A, Nagamuttu R.

Indian J Plast Surg. 2019 May;52(2):153-159. doi: 10.1055/s-0039-1696864. Epub 2019 Sep 10. Review.

4.

The CXCL5/CXCR2 axis is sufficient to promote breast cancer colonization during bone metastasis.

Romero-Moreno R, Curtis KJ, Coughlin TR, Cristina Miranda-Vergara M, Dutta S, Natarajan A, Facchine BA, Jackson KM, Nystrom L, Li J, Kaliney W, Niebur GL, Littlepage LE.

Nat Commun. 2019 Sep 27;10(1):4404. doi: 10.1038/s41467-019-12108-6.

5.

Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions.

Nowialis P, Lopusna K, Opavska J, Haney SL, Abraham A, Sheng P, Riva A, Natarajan A, Guryanova O, Simpson M, Hlady R, Xie M, Opavsky R.

Nat Commun. 2019 Sep 26;10(1):4374. doi: 10.1038/s41467-019-12355-7.

6.

A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1.

Zheng XF, Acharya SS, Choe KN, Nikhil K, Adelmant G, Satapathy SR, Sharma S, Viccaro K, Rana S, Natarajan A, Sicinski P, Marto JA, Shah K, Chowdhury D.

Nat Commun. 2019 Sep 18;10(1):4252. doi: 10.1038/s41467-019-12084-x.

7.

Initial experience of Ga-68 prostate-specific membrane antigen positron emission tomography/computed tomography imaging in evaluation of biochemical recurrence in prostate cancer patients.

Natarajan A, Agrawal A, Murthy V, Bakshi G, Joshi A, Purandare N, Shah S, Puranik A, Rangarajan V.

World J Nucl Med. 2019 Jul-Sep;18(3):244-250. doi: 10.4103/wjnm.WJNM_47_18.

8.

Temporal Characterization of Neuronal Migration Behavior on Chemically Patterned Neuronal Circuits in a Defined in Vitro Environment.

Natarajan A, Smith AST, Berry B, Lambert S, Molnar P, Hickman JJ.

ACS Biomater Sci Eng. 2018 Oct 8;4(10):3460-3470. doi: 10.1021/acsbiomaterials.8b00610. Epub 2018 Aug 27.

9.

CDK5 Inhibitor Downregulates Mcl-1 and Sensitizes Pancreatic Cancer Cell Lines to Navitoclax.

Kour S, Rana S, Contreras JI, King HM, Robb CM, Sonawane YA, Bendjennat M, Crawford AJ, Barger CJ, Kizhake S, Luo X, Hollingsworth MA, Natarajan A.

Mol Pharmacol. 2019 Oct;96(4):419-429. doi: 10.1124/mol.119.116855.

PMID:
31467029
10.

Barriers to timely surgery for breast cancer in Rwanda.

Schleimer LE, Vianney Dusengimana JM, Butonzi J, Kigonya C, Natarajan A, Umwizerwa A, O'Neil DS, Costas-Chavarri A, Majyambere JP, Shulman LN, Keating NL, Shyirambere C, Mpunga T, Pace LE.

Surgery. 2019 Aug 26. pii: S0039-6060(19)30406-4. doi: 10.1016/j.surg.2019.06.021. [Epub ahead of print]

PMID:
31466858
11.

Toward Building the Neuromuscular Junction: In Vitro Models To Study Synaptogenesis and Neurodegeneration.

Natarajan A, Sethumadhavan A, Krishnan UM.

ACS Omega. 2019 Jul 31;4(7):12969-12977. doi: 10.1021/acsomega.9b00973. eCollection 2019 Jul 31. Review.

12.

FN3 Protein Conjugates for Cancer Diagnosis and Imaging Studies.

Natarajan A, Abou-Elkacem L.

Methods Mol Biol. 2019;2033:301-313. doi: 10.1007/978-1-4939-9654-4_20.

PMID:
31332762
13.

Highly bright and stable NIR-BRET with blue-shifted coelenterazine derivatives for deep-tissue imaging of molecular events in vivo.

Nishihara R, Paulmurugan R, Nakajima T, Yamamoto E, Natarajan A, Afjei R, Hiruta Y, Iwasawa N, Nishiyama S, Citterio D, Sato M, Kim SB, Suzuki K.

Theranostics. 2019 Apr 13;9(9):2646-2661. doi: 10.7150/thno.32219. eCollection 2019.

14.

Flow injection ionization-tandem mass spectrometry-based estimation of a panel of lysophosphatidylcholines in dried blood spots for screening of X-linked adrenoleukodystrophy.

Natarajan A, Christopher R, Netravathi M, Bhat MD, Chandra SR.

Clin Chim Acta. 2019 Aug;495:167-173. doi: 10.1016/j.cca.2019.04.059. Epub 2019 Apr 10.

PMID:
30980791
15.

Selective degradation of CDK6 by a palbociclib based PROTAC.

Rana S, Bendjennat M, Kour S, King HM, Kizhake S, Zahid M, Natarajan A.

Bioorg Med Chem Lett. 2019 Jun 1;29(11):1375-1379. doi: 10.1016/j.bmcl.2019.03.035. Epub 2019 Mar 26.

PMID:
30935795
16.

Molecular identification and biocontrol activity of sugarcane rhizosphere bacteria against red rot pathogen Colletotrichum falcatum.

Patel P, Shah R, Joshi B, Ramar K, Natarajan A.

Biotechnol Rep (Amst). 2019 Feb 15;21:e00317. doi: 10.1016/j.btre.2019.e00317. eCollection 2019 Mar.

17.

Rate of Progression through a Continuum of Transit-Amplifying Progenitor Cell States Regulates Blood Cell Production.

Li H, Natarajan A, Ezike J, Barrasa MI, Le Y, Feder ZA, Yang H, Ma C, Markoulaki S, Lodish HF.

Dev Cell. 2019 Apr 8;49(1):118-129.e7. doi: 10.1016/j.devcel.2019.01.026. Epub 2019 Feb 28.

PMID:
30827895
18.

Glyco-recoded Escherichia coli: Recombineering-based genome editing of native polysaccharide biosynthesis gene clusters.

Yates LE, Natarajan A, Li M, Hale ME, Mills DC, DeLisa MP.

Metab Eng. 2019 May;53:59-68. doi: 10.1016/j.ymben.2019.02.002. Epub 2019 Feb 14.

PMID:
30772453
19.

Pre-Vent: the prematurity-related ventilatory control study.

Dennery PA, Di Fiore JM, Ambalavanan N, Bancalari E, Carroll JL, Claure N, Hamvas A, Hibbs AM, Indic P, Kemp J, Krahn KN, Lake D, Laposky A, Martin RJ, Natarajan A, Rand C, Schau M, Weese-Mayer DE, Zimmet AM, Moorman JR.

Pediatr Res. 2019 May;85(6):769-776. doi: 10.1038/s41390-019-0317-8. Epub 2019 Feb 1.

20.

A simple fluorescent assay for the discovery of protein-protein interaction inhibitors.

Al-Mugotir M, Kolar C, Vance K, Kelly DL, Natarajan A, Borgstahl GEO.

Anal Biochem. 2019 Mar 15;569:46-52. doi: 10.1016/j.ab.2019.01.010. Epub 2019 Jan 30.

21.

New de novo assembly of the Atlantic bottlenose dolphin (Tursiops truncatus) improves genome completeness and provides haplotype phasing.

Martinez-Viaud KA, Lawley CT, Vergara MM, Ben-Zvi G, Biniashvili T, Baruch K, St Leger J, Le J, Natarajan A, Rivera M, Guillergan M, Jaeger E, Steffy B, Zimin A.

Gigascience. 2019 Mar 1;8(3). pii: giy168. doi: 10.1093/gigascience/giy168.

22.

Connecting the Simpler Structures to Topologically Close-Packed Phases.

Natarajan AR, Van der Ven A.

Phys Rev Lett. 2018 Dec 21;121(25):255701. doi: 10.1103/PhysRevLett.121.255701.

PMID:
30608772
23.

Efficient Segmentation of Brain Tumor Using FL-SNM with a Metaheuristic Approach to Optimization.

Natarajan A, Kumarasamy S.

J Med Syst. 2019 Jan 2;43(2):25. doi: 10.1007/s10916-018-1135-y.

PMID:
30604101
24.

Tumor treating fields increases membrane permeability in glioblastoma cells.

Chang E, Patel CB, Pohling C, Young C, Song J, Flores TA, Zeng Y, Joubert LM, Arami H, Natarajan A, Sinclair R, Gambhir SS.

Cell Death Discov. 2018 Dec 5;4:113. doi: 10.1038/s41420-018-0130-x. eCollection 2018.

25.

A DNA Origami-Based Chiral Plasmonic Sensing Device.

Huang Y, Nguyen MK, Natarajan AK, Nguyen VH, Kuzyk A.

ACS Appl Mater Interfaces. 2018 Dec 26;10(51):44221-44225. doi: 10.1021/acsami.8b19153. Epub 2018 Dec 11.

PMID:
30525378
26.

The myriad targets of a T cell.

Natarajan A, Krogsgaard M.

Nat Biotechnol. 2018 Dec 6;36(12):1152-1154. doi: 10.1038/nbt.4309. No abstract available.

PMID:
30520863
27.

A Novel Engineered Small Protein for Positron Emission Tomography Imaging of Human Programmed Death Ligand-1: Validation in Mouse Models and Human Cancer Tissues.

Natarajan A, Patel CB, Ramakrishnan S, Panesar PS, Long SR, Gambhir SS.

Clin Cancer Res. 2019 Mar 15;25(6):1774-1785. doi: 10.1158/1078-0432.CCR-18-1871. Epub 2018 Oct 29.

PMID:
30373750
28.

Spontaneous Celiac Artery Dissection Presenting With Splenic Infarction: A Case Report.

Abugroun A, Natarajan A, Daoud H, Khalaf H.

Gastroenterology Res. 2018 Oct;11(5):379-382. doi: 10.14740/gr1065w. Epub 2018 Oct 1.

29.

Synthesis of aminopyrazole analogs and their evaluation as CDK inhibitors for cancer therapy.

Rana S, Sonawane YA, Taylor MA, Kizhake S, Zahid M, Natarajan A.

Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3736-3740. doi: 10.1016/j.bmcl.2018.10.020. Epub 2018 Oct 15.

PMID:
30343954
30.

Genetics of Hypercoagulable and Hypocoagulable States.

Singh D, Natarajan A, Nand S, Mai HP.

Neurosurg Clin N Am. 2018 Oct;29(4):493-501. doi: 10.1016/j.nec.2018.06.002. Review.

PMID:
30223962
31.

The First Report of Small Cell Cancer of the Uvula Presenting With Ectopic Adrenocorticotropic Hormone Syndrome.

Natarajan A, Abugroun A, Khan A, Jahangir N.

World J Oncol. 2018 Aug;9(4):115-118. doi: 10.14740/wjon1130w. Epub 2018 Sep 6.

32.

Effect of dietary supplementation of cinnamon oil and sodium butyrate on carcass characteristics and meat quality of broiler chicken.

Gomathi G, Senthilkumar S, Natarajan A, Amutha R, Purushothaman MR.

Vet World. 2018 Jul;11(7):959-964. doi: 10.14202/vetworld.2018.959-964. Epub 2018 Jul 18.

33.

Author Correction: Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP.

Nat Commun. 2018 Aug 20;9(1):3396. doi: 10.1038/s41467-018-05620-8.

34.

Quantification of Cerenkov Luminescence Imaging (CLI) Comparable With 3-D PET Standard Measurements.

Habte F, Natarajan A, Paik DS, Gambhir SS.

Mol Imaging. 2018 Jan-Dec;17:1536012118788637. doi: 10.1177/1536012118788637.

35.

Liquid chromatography-tandem mass spectrometry method for estimation of a panel of lysophosphatidylcholines in dried blood spots for screening of X-linked adrenoleukodystrophy.

Natarajan A, Christopher R, Netravathi M, Bhat M, Chandra SR.

Clin Chim Acta. 2018 Oct;485:305-310. doi: 10.1016/j.cca.2018.07.007. Epub 2018 Jul 7.

PMID:
30018013
36.

Hodgkin-Huxley Neuron and FPAA Dynamics.

Natarajan A, Hasler J.

IEEE Trans Biomed Circuits Syst. 2018 Aug;12(4):918-926. doi: 10.1109/TBCAS.2018.2837055. Epub 2018 Jul 13.

PMID:
30010587
37.

Single-pot glycoprotein biosynthesis using a cell-free transcription-translation system enriched with glycosylation machinery.

Jaroentomeechai T, Stark JC, Natarajan A, Glasscock CJ, Yates LE, Hsu KJ, Mrksich M, Jewett MC, DeLisa MP.

Nat Commun. 2018 Jul 12;9(1):2686. doi: 10.1038/s41467-018-05110-x. Erratum in: Nat Commun. 2018 Aug 20;9(1):3396.

38.

Structural Coupling Throughout the Active Site Hydrogen Bond Networks of Ketosteroid Isomerase and Photoactive Yellow Protein.

Pinney MM, Natarajan A, Yabukarski F, Sanchez DM, Liu F, Liang R, Doukov T, Schwans JP, Martinez TJ, Herschlag D.

J Am Chem Soc. 2018 Aug 8;140(31):9827-9843. doi: 10.1021/jacs.8b01596. Epub 2018 Jul 27.

PMID:
29990421
39.

Outcomes of Closed Versus Open Technique of Rhinoplasty During Primary Repair of Unilateral Cleft Lip: A Systematic Review.

Jayarajan R, Natarajan A, Nagamuttu R.

Cleft Palate Craniofac J. 2019 Jan;56(1):74-83. doi: 10.1177/1055665618787689. Epub 2018 Jul 10.

PMID:
29989835
40.

Ferulic acid dimer as a non-opioid therapeutic for acute pain.

Priebe A, Hunke M, Tonello R, Sonawane Y, Berta T, Natarajan A, Bhuvanesh N, Pattabiraman M, Chandra S.

J Pain Res. 2018 Jun 6;11:1075-1085. doi: 10.2147/JPR.S161161. eCollection 2018.

41.

Mouse Pancreatic Tumor Model Independent of Tumor Suppressor Gene Inactivation.

Naramura M, Natarajan A.

Pancreas. 2018 May/Jun;47(5):e27-e29. doi: 10.1097/MPA.0000000000001041. No abstract available.

42.

A blood biomarker for monitoring response to anti-EGFR therapy.

Hughes NP, Xu L, Nielsen CH, Chang E, Hori SS, Natarajan A, Lee S, Kjær A, Kani K, Wang SX, Mallick P, Gambhir SS.

Cancer Biomark. 2018;22(2):333-344. doi: 10.3233/CBM-171149.

PMID:
29689709
43.

Role of Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Various Orbital Malignancies.

Natarajan A, Chandra P, Purandare N, Agrawal A, Shah S, Puranik A, Rangarajan V.

Indian J Nucl Med. 2018 Apr-Jun;33(2):118-124. doi: 10.4103/ijnm.IJNM_135_17.

44.

Author Correction: Analysis of inflammatory cytokine and TLR expression levels in Type 2 Diabetes with complications.

Gupta S, Maratha A, Siednienko J, Natarajan A, Gajanayake T, Hoashi S, Miggin S.

Sci Rep. 2018 Apr 5;8(1):5768. doi: 10.1038/s41598-018-23475-3.

45.

Chemical Genetic Screens Identify Kinase Inhibitor Combinations that Target Anti-Apoptotic Proteins for Cancer Therapy.

Contreras JI, Robb CM, King HM, Baxter J, Crawford AJ, Kour S, Kizhake S, Sonawane YA, Rana S, Hollingsworth MA, Luo X, Natarajan A.

ACS Chem Biol. 2018 May 18;13(5):1148-1152. doi: 10.1021/acschembio.8b00077. Epub 2018 Apr 5.

46.

Characterization of CDK(5) inhibitor, 20-223 (aka CP668863) for colorectal cancer therapy.

Robb CM, Kour S, Contreras JI, Agarwal E, Barger CJ, Rana S, Sonawane Y, Neilsen BK, Taylor M, Kizhake S, Thakare RN, Chowdhury S, Wang J, Black JD, Hollingsworth MA, Brattain MG, Natarajan A.

Oncotarget. 2017 Dec 28;9(4):5216-5232. doi: 10.18632/oncotarget.23749. eCollection 2018 Jan 12.

47.

Mitochondrial dysfunction in human skeletal muscle biopsies of lipid storage disorder.

Debashree B, Kumar M, Keshava Prasad TS, Natarajan A, Christopher R, Nalini A, Bindu PS, Gayathri N, Srinivas Bharath MM.

J Neurochem. 2018 May;145(4):323-341. doi: 10.1111/jnc.14318. Epub 2018 Apr 19.

48.

Structure-Activity Relationship Studies with Tetrahydroquinoline Analogs as EPAC Inhibitors.

Sonawane YA, Zhu Y, Garrison JC, Ezell EL, Zahid M, Cheng X, Natarajan A.

ACS Med Chem Lett. 2017 Oct 2;8(11):1183-1187. doi: 10.1021/acsmedchemlett.7b00358. eCollection 2017 Nov 9.

49.

Impact of structurally modifying hyaluronic acid on CD44 interaction.

Bhattacharya D, Svechkarev D, Souchek JJ, Hill TK, Taylor MA, Natarajan A, Mohs AM.

J Mater Chem B. 2017;5(41):8183-8192. doi: 10.1039/C7TB01895A. Epub 2017 Sep 20.

50.

Dosimetry Prediction for Clinical Translation of 64Cu-Pembrolizumab ImmunoPET Targeting Human PD-1 Expression.

Natarajan A, Patel CB, Habte F, Gambhir SS.

Sci Rep. 2018 Jan 12;8(1):633. doi: 10.1038/s41598-017-19123-x.

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