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Items: 31


Repurposing Drugs for Cancer Radiotherapy: Early Successes and Emerging Opportunities.

Khan MK, Nasti TH, Buchwald ZS, Weichselbaum RR, Kron SJ.

Cancer J. 2019 Mar/Apr;25(2):106-115. doi: 10.1097/PPO.0000000000000369.


Radiation, Immune Checkpoint Blockade and the Abscopal Effect: A Critical Review on Timing, Dose and Fractionation.

Buchwald ZS, Wynne J, Nasti TH, Zhu S, Mourad WF, Yan W, Gupta S, Khleif SN, Khan MK.

Front Oncol. 2018 Dec 13;8:612. doi: 10.3389/fonc.2018.00612. eCollection 2018. Review.


Exosomes, Their Biogenesis and Role in Inter-Cellular Communication, Tumor Microenvironment and Cancer Immunotherapy.

Jella KK, Nasti TH, Li Z, Malla SR, Buchwald ZS, Khan MK.

Vaccines (Basel). 2018 Sep 26;6(4). pii: E69. doi: 10.3390/vaccines6040069. Review.


T cell receptor sequencing of activated CD8 T cells in the blood identifies tumor-infiltrating clones that expand after PD-1 therapy and radiation in a melanoma patient.

Wieland A, Kamphorst AO, Adsay NV, Masor JJ, Sarmiento J, Nasti TH, Darko S, Douek DC, Xue Y, Curran WJ, Lawson DH, Ahmed R.

Cancer Immunol Immunother. 2018 Nov;67(11):1767-1776. doi: 10.1007/s00262-018-2228-7. Epub 2018 Aug 22.


Myocarditis With Radiotherapy and Immunotherapy in Multiple Myeloma.

Chang A, Nasti TH, Khan MK, Parashar S, Kaufman JL, Boise LH, Lonial S, Ahmed R, Nooka AK.

J Oncol Pract. 2018 Sep;14(9):561-564. doi: 10.1200/JOP.18.00208. Epub 2018 Jul 13. No abstract available.


4-1BB (CD137) and radiation therapy: A case report and literature review.

Shiao JC, Bowers N, Nasti TH, Khosa F, Khan MK.

Adv Radiat Oncol. 2017 Apr 4;2(3):398-402. doi: 10.1016/j.adro.2017.03.007. eCollection 2017 Jul-Sep. No abstract available.


Proliferation of PD-1+ CD8 T cells in peripheral blood after PD-1-targeted therapy in lung cancer patients.

Kamphorst AO, Pillai RN, Yang S, Nasti TH, Akondy RS, Wieland A, Sica GL, Yu K, Koenig L, Patel NT, Behera M, Wu H, McCausland M, Chen Z, Zhang C, Khuri FR, Owonikoko TK, Ahmed R, Ramalingam SS.

Proc Natl Acad Sci U S A. 2017 May 9;114(19):4993-4998. doi: 10.1073/pnas.1705327114. Epub 2017 Apr 26.


Rescue of exhausted CD8 T cells by PD-1-targeted therapies is CD28-dependent.

Kamphorst AO, Wieland A, Nasti T, Yang S, Zhang R, Barber DL, Konieczny BT, Daugherty CZ, Koenig L, Yu K, Sica GL, Sharpe AH, Freeman GJ, Blazar BR, Turka LA, Owonikoko TK, Pillai RN, Ramalingam SS, Araki K, Ahmed R.

Science. 2017 Mar 31;355(6332):1423-1427. doi: 10.1126/science.aaf0683. Epub 2017 Mar 9.


IL-23 Inhibits Melanoma Development by Augmenting DNA Repair and Modulating T Cell Subpopulations.

Nasti TH, Cochran JB, Vachhani RV, McKay K, Tsuruta Y, Athar M, Timares L, Elmets CA.

J Immunol. 2017 Jan 15;198(2):950-961. doi: 10.4049/jimmunol.1601455. Epub 2016 Dec 21.


Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy.

Im SJ, Hashimoto M, Gerner MY, Lee J, Kissick HT, Burger MC, Shan Q, Hale JS, Lee J, Nasti TH, Sharpe AH, Freeman GJ, Germain RN, Nakaya HI, Xue HH, Ahmed R.

Nature. 2016 Sep 15;537(7620):417-421. doi: 10.1038/nature19330. Epub 2016 Aug 2.


P-selectin enhances growth and metastasis of mouse mammary tumors by promoting regulatory T cell infiltration into the tumors.

Nasti TH, Bullard DC, Yusuf N.

Life Sci. 2015 Jun 15;131:11-8. doi: 10.1016/j.lfs.2015.02.025. Epub 2015 Apr 10.


In Vivo Suppression of Heat Shock Protein (HSP)27 and HSP70 Accelerates DMBA-Induced Skin Carcinogenesis by Inducing Antigenic Unresponsiveness to the Initiating Carcinogenic Chemical.

Yusuf N, Nasti TH, Ahmad I, Chowdhury S, Mohiuddin H, Xu H, Athar M, Timares L, Elmets CA.

J Immunol. 2015 May 15;194(10):4796-803. doi: 10.4049/jimmunol.1402804. Epub 2015 Apr 3.


A murine model for the development of melanocytic nevi and their progression to melanoma.

Nasti TH, Cochran JB, Tsuruta Y, Yusuf N, McKay KM, Athar M, Timares L, Elmets CA.

Mol Carcinog. 2016 May;55(5):646-58. doi: 10.1002/mc.22310. Epub 2015 Mar 18.


Immunoprevention of chemical carcinogenesis through early recognition of oncogene mutations.

Nasti TH, Rudemiller KJ, Cochran JB, Kim HK, Tsuruta Y, Fineberg NS, Athar M, Elmets CA, Timares L.

J Immunol. 2015 Mar 15;194(6):2683-95. doi: 10.4049/jimmunol.1402125. Epub 2015 Feb 18.


MC1R, eumelanin and pheomelanin: their role in determining the susceptibility to skin cancer.

Nasti TH, Timares L.

Photochem Photobiol. 2015 Jan-Feb;91(1):188-200. doi: 10.1111/php.12335. Epub 2014 Nov 7. Review.


The old but new IgM Fc receptor (FcμR).

Kubagawa H, Kubagawa Y, Jones D, Nasti TH, Walter MR, Honjo K.

Curr Top Microbiol Immunol. 2014;382:3-28. doi: 10.1007/978-3-319-07911-0_1. Review.


Biological properties of carbon powders synthesized using chemical vapour deposition and detonation methods.

Batory M, Batory D, Grabarczyk J, Kaczorowski W, Kupcewicz B, Mitura K, Nasti TH, Yusuf N, Niedzielski P.

J Nanosci Nanotechnol. 2012 Dec;12(12):9037-46.


Inflammasome activation of IL-1 family mediators in response to cutaneous photodamage.

Nasti TH, Timares L.

Photochem Photobiol. 2012 Sep-Oct;88(5):1111-25. doi: 10.1111/j.1751-1097.2012.01182.x. Epub 2012 Jul 9. Review.


The antiproliferative function of violacein-like purple violet pigment (PVP) from an Antarctic Janthinobacterium sp. Ant5-2 in UV-induced 2237 fibrosarcoma.

Mojib N, Nasti TH, Andersen DT, Attigada VR, Hoover RB, Yusuf N, Bej AK.

Int J Dermatol. 2011 Oct;50(10):1223-33. doi: 10.1111/j.1365-4632.2010.04825.x. Epub 2011 Jul 26.


Cell mediated immune responses through TLR4 prevents DMBA-induced mammary carcinogenesis in mice.

Naseemuddin M, Iqbal A, Nasti TH, Ghandhi JL, Kapadia AD, Yusuf N.

Int J Cancer. 2012 Feb 15;130(4):765-74. doi: 10.1002/ijc.26100. Epub 2011 Jun 18.


Regulation of ultraviolet radiation induced cutaneous photoimmunosuppression by toll-like receptor-4.

Lewis W, Simanyi E, Li H, Thompson CA, Nasti TH, Jaleel T, Xu H, Yusuf N.

Arch Biochem Biophys. 2011 Apr 15;508(2):171-7. doi: 10.1016/ Epub 2011 Jan 12.


Differential roles of T-cell subsets in regulation of ultraviolet radiation induced cutaneous photocarcinogenesis.

Nasti TH, Iqbal O, Tamimi IA, Geise JT, Katiyar SK, Yusuf N.

Photochem Photobiol. 2011 Mar-Apr;87(2):387-98. doi: 10.1111/j.1751-1097.2010.00859.x. Epub 2010 Dec 8.


Resveratrol enhances cell-mediated immune response to DMBA through TLR4 and prevents DMBA induced cutaneous carcinogenesis.

Yusuf N, Nasti TH, Meleth S, Elmets CA.

Mol Carcinog. 2009 Aug;48(8):713-23. doi: 10.1002/mc.20517.


Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity.

Yusuf N, Nasti TH, Huang CM, Huber BS, Jaleel T, Lin HY, Xu H, Elmets CA.

J Immunol. 2009 Jan 1;182(1):675-83.


Antagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesis.

Yusuf N, Nasti TH, Katiyar SK, Jacobs MK, Seibert MD, Ginsburg AC, Timares L, Xu H, Elmets CA.

Cancer Res. 2008 May 15;68(10):3924-30. doi: 10.1158/0008-5472.CAN-07-3059.


Protective role of Toll-like receptor 4 during the initiation stage of cutaneous chemical carcinogenesis.

Yusuf N, Nasti TH, Long JA, Naseemuddin M, Lucas AP, Xu H, Elmets CA.

Cancer Res. 2008 Jan 15;68(2):615-22. doi: 10.1158/0008-5472.CAN-07-5219. Erratum in: Cancer Res. 2008 Mar 1;68(5):1609.


Enhanced efficacy of pH-sensitive nystatin liposomes against Cryptococcus neoformans in murine model.

Nasti TH, Khan MA, Owais M.

J Antimicrob Chemother. 2006 Feb;57(2):349-52. Epub 2005 Dec 20.


Incorporation of amphotericin B in tuftsin-bearing liposomes showed enhanced efficacy against systemic cryptococcosis in leucopenic mice.

Khan MA, Nasti TH, Owais M.

J Antimicrob Chemother. 2005 Oct;56(4):726-31. Epub 2005 Aug 26.


Enhanced anticryptococcal activity of chloroquine in phosphatidylserine-containing liposomes in a murine model.

Khan MA, Jabeen R, Nasti TH, Mohammad O.

J Antimicrob Chemother. 2005 Feb;55(2):223-8. Epub 2004 Dec 8.


Co-administration of immunomodulator tuftsin and liposomised nystatin can combat less susceptible Candida albicans infection in temporarily neutropenic mice.

Khan MA, Nasti TH, Saima K, Mallick AI, Firoz A, Wajahul H, Ahmad N, Mohammad O.

FEMS Immunol Med Microbiol. 2004 Jul 1;41(3):249-58.


Antigen entrapped in the escheriosomes leads to the generation of CD4(+) helper and CD8(+) cytotoxic T cell response.

Syed FM, Khan MA, Nasti TH, Ahmad N, Mohammad O.

Vaccine. 2003 Jun 2;21(19-20):2383-93.


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