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Renal matrix Gla protein expression increases progressively with CKD and predicts renal outcome.

Miyata KN, Nast CC, Dai T, Dukkipati R, LaPage JA, Troost JP, Schurgers LJ, Kretzler M, Adler SG.

Exp Mol Pathol. 2018 Aug;105(1):120-129. doi: 10.1016/j.yexmp.2018.07.001. Epub 2018 Jul 6.


Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices.

Bajema IM, Wilhelmus S, Alpers CE, Bruijn JA, Colvin RB, Cook HT, D'Agati VD, Ferrario F, Haas M, Jennette JC, Joh K, Nast CC, Noël LH, Rijnink EC, Roberts ISD, Seshan SV, Sethi S, Fogo AB.

Kidney Int. 2018 Apr;93(4):789-796. doi: 10.1016/j.kint.2017.11.023. Epub 2018 Feb 16.


Changing concepts of HIV infection and renal disease.

Hou J, Nast CC.

Curr Opin Nephrol Hypertens. 2018 May;27(3):144-152. doi: 10.1097/MNH.0000000000000400.


Plasma Exosomes From HLA-Sensitized Kidney Transplant Recipients Contain mRNA Transcripts Which Predict Development of Antibody-Mediated Rejection.

Zhang H, Huang E, Kahwaji J, Nast CC, Li P, Mirocha J, Thomas DL, Ge S, Vo AA, Jordan SC, Toyoda M.

Transplantation. 2017 Oct;101(10):2419-2428. doi: 10.1097/TP.0000000000001834.


A proposal for standardized grading of chronic changes in native kidney biopsy specimens.

Sethi S, D'Agati VD, Nast CC, Fogo AB, De Vriese AS, Markowitz GS, Glassock RJ, Fervenza FC, Seshan SV, Rule A, Racusen LC, Radhakrishnan J, Winearls CG, Appel GB, Bajema IM, Chang A, Colvin RB, Cook HT, Hariharan S, Herrera Hernandez LP, Kambham N, Mengel M, Nath KA, Rennke HG, Ronco P, Rovin BH, Haas M.

Kidney Int. 2017 Apr;91(4):787-789. doi: 10.1016/j.kint.2017.01.002.


Medication-Induced Interstitial Nephritis in the 21st Century.

Nast CC.

Adv Chronic Kidney Dis. 2017 Mar;24(2):72-79. doi: 10.1053/j.ackd.2016.11.016. Review.


The Renal Tubulointerstitium.

Nast CC.

Adv Chronic Kidney Dis. 2017 Mar;24(2):55-56. doi: 10.1053/j.ackd.2016.11.015. No abstract available.


A Case of Henoch-Schonlein Purpura Associated with Rotavirus Infection in an Elderly Asian Male and Review of the Literature.

Tang C, Scaramangas-Plumley D, Nast CC, Mosenifar Z, Edelstein MA, Weisman M.

Am J Case Rep. 2017 Feb 8;18:136-142. Review.


Collapsing glomerulopathy in a young woman with APOL1 risk alleles following acute parvovirus B19 infection: a case report investigation.

Besse W, Mansour S, Jatwani K, Nast CC, Brewster UC.

BMC Nephrol. 2016 Sep 6;17(1):125. doi: 10.1186/s12882-016-0330-7.


The Application of Digital Pathology to Improve Accuracy in Glomerular Enumeration in Renal Biopsies.

Rosenberg AZ, Palmer M, Merlino L, Troost JP, Gasim A, Bagnasco S, Avila-Casado C, Johnstone D, Hodgin JB, Conway C, Gillespie BW, Nast CC, Barisoni L, Hewitt SM.

PLoS One. 2016 Jun 16;11(6):e0156441. doi: 10.1371/journal.pone.0156441. eCollection 2016.


Morphometry Predicts Early GFR Change in Primary Proteinuric Glomerulopathies: A Longitudinal Cohort Study Using Generalized Estimating Equations.

Lemley KV, Bagnasco SM, Nast CC, Barisoni L, Conway CM, Hewitt SM, Song PX.

PLoS One. 2016 Jun 10;11(6):e0157148. doi: 10.1371/journal.pone.0157148. eCollection 2016.


Complete Remission in the Nephrotic Syndrome Study Network.

Gipson DS, Troost JP, Lafayette RA, Hladunewich MA, Trachtman H, Gadegbeku CA, Sedor JR, Holzman LB, Moxey-Mims MM, Perumal K, Kaskel FJ, Nelson PJ, Tuttle KR, Bagnasco SM, Hogan MC, Dell KM, Appel GB, Lieske JC, Ilori TO, Sethna CB, Fervenza FC, Hogan SL, Nachman PH, Rosenberg AZ, Greenbaum LA, Meyers KE, Hewitt SM, Choi MJ, Kopp JB, Zhdanova O, Hodgin JB, Johnstone DB, Adler SG, Avila-Casado C, Neu AM, Hingorani SR, Lemley KV, Nast CC, Brady TM, Barisoni-Thomas L, Fornoni A, Jennette JC, Cattran DC, Palmer MB, Gibson KL, Reich HN, Mokrzycki MH, Sambandam KK, Zilleruelo GE, Licht C, Sampson MG, Song P, Mariani LH, Kretzler M.

Clin J Am Soc Nephrol. 2016 Jan 7;11(1):81-9. doi: 10.2215/CJN.02560315. Epub 2015 Dec 10.


Morphology in the Digital Age: Integrating High-Resolution Description of Structural Alterations With Phenotypes and Genotypes.

Nast CC, Lemley KV, Hodgin JB, Bagnasco S, Avila-Casado C, Hewitt SM, Barisoni L.

Semin Nephrol. 2015 May;35(3):266-78. doi: 10.1016/j.semnephrol.2015.04.006. Review.


Clinical Features and Histology of Apolipoprotein L1-Associated Nephropathy in the FSGS Clinical Trial.

Kopp JB, Winkler CA, Zhao X, Radeva MK, Gassman JJ, D'Agati VD, Nast CC, Wei C, Reiser J, Guay-Woodford LM, Pollak MR, Hildebrandt F, Moxey-Mims M, Gipson DS, Trachtman H, Friedman AL, Kaskel FJ; FSGS-CT Study Consortium.

J Am Soc Nephrol. 2015 Jun;26(6):1443-8. doi: 10.1681/ASN.2013111242. Epub 2015 Jan 8.


Genes associated with antibody-dependent cell activation are overexpressed in renal biopsies from patients with antibody-mediated rejection.

Suviolahti E, Ge S, Nast CC, Mirocha J, Karasyov A, White M, Jordan SC, Toyoda M.

Transpl Immunol. 2015 Jan;32(1):9-17. doi: 10.1016/j.trim.2014.11.215. Epub 2014 Nov 13.


Severe vascular calcification and tumoral calcinosis in a family with hyperphosphatemia: a fibroblast growth factor 23 mutation identified by exome sequencing.

Shah A, Miller CJ, Nast CC, Adams MD, Truitt B, Tayek JA, Tong L, Mehtani P, Monteon F, Sedor JR, Clinkenbeard EL, White K, Mehrotra R, LaPage J, Dickson P, Adler SG, Iyengar SK.

Nephrol Dial Transplant. 2014 Dec;29(12):2235-43. doi: 10.1093/ndt/gfu324. Epub 2014 Nov 5.


Heterogeneity of mprF sequences in methicillin-resistant Staphylococcus aureus clinical isolates: role in cross-resistance between daptomycin and host defense antimicrobial peptides.

Bayer AS, Mishra NN, Sakoulas G, Nonejuie P, Nast CC, Pogliano J, Chen KT, Ellison SN, Yeaman MR, Yang SJ.

Antimicrob Agents Chemother. 2014 Dec;58(12):7462-7. doi: 10.1128/AAC.03422-14. Epub 2014 Oct 6.


Phenotypic and genotypic characterization of daptomycin-resistant methicillin-resistant Staphylococcus aureus strains: relative roles of mprF and dlt operons.

Mishra NN, Bayer AS, Weidenmaier C, Grau T, Wanner S, Stefani S, Cafiso V, Bertuccio T, Yeaman MR, Nast CC, Yang SJ.

PLoS One. 2014 Sep 16;9(9):e107426. doi: 10.1371/journal.pone.0107426. eCollection 2014.


Permeability factors in focal and segmental glomerulosclerosis.

Reiser J, Nast CC, Alachkar N.

Adv Chronic Kidney Dis. 2014 Sep;21(5):417-21. doi: 10.1053/j.ackd.2014.05.010. Review.


Focal and segmental glomerulosclerosis--are we there yet?

Jefferson JA, Nast CC.

Adv Chronic Kidney Dis. 2014 Sep;21(5):398-9. doi: 10.1053/j.ackd.2014.05.008. No abstract available.


Janus kinase signaling activation mediates peritoneal inflammation and injury in vitro and in vivo in response to dialysate.

Dai T, Wang Y, Nayak A, Nast CC, Quang L, LaPage J, Andalibi A, Adler SG.

Kidney Int. 2014 Dec;86(6):1187-96. doi: 10.1038/ki.2014.209. Epub 2014 Jul 9.


Membranoproliferative glomerulonephritis in patients with chronic venous catheters: a case report and literature review.

Sy J, Nast CC, Pham PT, Pham PC.

Case Rep Nephrol. 2014;2014:159370. doi: 10.1155/2014/159370. Epub 2014 Jan 30.


Characterization and outcomes of renal leukocyte chemotactic factor 2-associated amyloidosis.

Said SM, Sethi S, Valeri AM, Chang A, Nast CC, Krahl L, Molloy P, Barry M, Fidler ME, Cornell LD, Leung N, Vrana JA, Theis JD, Dogan A, Nasr SH.

Kidney Int. 2014 Aug;86(2):370-7. doi: 10.1038/ki.2013.558. Epub 2014 Jan 22.


C3 glomerulopathy: consensus report.

Pickering MC, D'Agati VD, Nester CM, Smith RJ, Haas M, Appel GB, Alpers CE, Bajema IM, Bedrosian C, Braun M, Doyle M, Fakhouri F, Fervenza FC, Fogo AB, Frémeaux-Bacchi V, Gale DP, Goicoechea de Jorge E, Griffin G, Harris CL, Holers VM, Johnson S, Lavin PJ, Medjeral-Thomas N, Paul Morgan B, Nast CC, Noel LH, Peters DK, Rodríguez de Córdoba S, Servais A, Sethi S, Song WC, Tamburini P, Thurman JM, Zavros M, Cook HT.

Kidney Int. 2013 Dec;84(6):1079-89. doi: 10.1038/ki.2013.377. Epub 2013 Oct 30.


Emergence of daptomycin resistance in daptomycin-naïve rabbits with methicillin-resistant Staphylococcus aureus prosthetic joint infection is associated with resistance to host defense cationic peptides and mprF polymorphisms.

Mishra NN, Yang SJ, Chen L, Muller C, Saleh-Mghir A, Kuhn S, Peschel A, Yeaman MR, Nast CC, Kreiswirth BN, Crémieux AC, Bayer AS.

PLoS One. 2013 Aug 19;8(8):e71151. doi: 10.1371/journal.pone.0071151. eCollection 2013.


Digital pathology evaluation in the multicenter Nephrotic Syndrome Study Network (NEPTUNE).

Barisoni L, Nast CC, Jennette JC, Hodgin JB, Herzenberg AM, Lemley KV, Conway CM, Kopp JB, Kretzler M, Lienczewski C, Avila-Casado C, Bagnasco S, Sethi S, Tomaszewski J, Gasim AH, Hewitt SM.

Clin J Am Soc Nephrol. 2013 Aug;8(8):1449-59. doi: 10.2215/CJN.08370812. Epub 2013 Feb 7.


Design of the Nephrotic Syndrome Study Network (NEPTUNE) to evaluate primary glomerular nephropathy by a multidisciplinary approach.

Gadegbeku CA, Gipson DS, Holzman LB, Ojo AO, Song PX, Barisoni L, Sampson MG, Kopp JB, Lemley KV, Nelson PJ, Lienczewski CC, Adler SG, Appel GB, Cattran DC, Choi MJ, Contreras G, Dell KM, Fervenza FC, Gibson KL, Greenbaum LA, Hernandez JD, Hewitt SM, Hingorani SR, Hladunewich M, Hogan MC, Hogan SL, Kaskel FJ, Lieske JC, Meyers KE, Nachman PH, Nast CC, Neu AM, Reich HN, Sedor JR, Sethna CB, Trachtman H, Tuttle KR, Zhdanova O, Zilleruelo GE, Kretzler M.

Kidney Int. 2013 Apr;83(4):749-56. doi: 10.1038/ki.2012.428. Epub 2013 Jan 16.


Reduced vancomycin susceptibility in an in vitro catheter-related biofilm model correlates with poor therapeutic outcomes in experimental endocarditis due to methicillin-resistant Staphylococcus aureus.

Abdelhady W, Bayer AS, Seidl K, Nast CC, Kiedrowski MR, Horswill AR, Yeaman MR, Xiong YQ.

Antimicrob Agents Chemother. 2013 Mar;57(3):1447-54. doi: 10.1128/AAC.02073-12. Epub 2013 Jan 7.


Association of histologic variants in FSGS clinical trial with presenting features and outcomes.

D'Agati VD, Alster JM, Jennette JC, Thomas DB, Pullman J, Savino DA, Cohen AH, Gipson DS, Gassman JJ, Radeva MK, Moxey-Mims MM, Friedman AL, Kaskel FJ, Trachtman H, Alpers CE, Fogo AB, Greene TH, Nast CC.

Clin J Am Soc Nephrol. 2013 Mar;8(3):399-406. doi: 10.2215/CJN.06100612. Epub 2012 Dec 6.


Oxidized low-density lipoprotein antigen transport induces autoimmunity in the renal tubulointerstitium.

Satirapoj B, Bruhn KW, Nast CC, Wang Y, Dai T, Lapage J, Wu X, Natarajan R, Adler SG.

Am J Nephrol. 2012;35(6):520-30. doi: 10.1159/000338484. Epub 2012 May 25.


Novel insights into the relationship between glomerular pathology and progressive kidney disease.

Satirapoj B, Nast CC, Adler SG.

Adv Chronic Kidney Dis. 2012 Mar;19(2):93-100. doi: 10.1053/j.ackd.2011.12.001. Review.


Infection-related glomerulonephritis: changing demographics and outcomes.

Nast CC.

Adv Chronic Kidney Dis. 2012 Mar;19(2):68-75. doi: 10.1053/j.ackd.2012.02.014. Review.


Glomerular grievances and CKD.

Nast CC, Barisoni L.

Adv Chronic Kidney Dis. 2012 Mar;19(2):59-60. doi: 10.1053/j.ackd.2012.02.012. No abstract available.


Periostin: novel tissue and urinary biomarker of progressive renal injury induces a coordinated mesenchymal phenotype in tubular cells.

Satirapoj B, Wang Y, Chamberlin MP, Dai T, LaPage J, Phillips L, Nast CC, Adler SG.

Nephrol Dial Transplant. 2012 Jul;27(7):2702-11. doi: 10.1093/ndt/gfr670. Epub 2011 Dec 13.


Medullary amyloidosis associated with apolipoprotein A-IV deposition.

Sethi S, Theis JD, Shiller SM, Nast CC, Harrison D, Rennke HG, Vrana JA, Dogan A.

Kidney Int. 2012 Jan;81(2):201-6. doi: 10.1038/ki.2011.316. Epub 2011 Sep 7.


Maternal undernutrition upregulates apoptosis in offspring nephrogenesis.

Tafti SA, Nast CC, Desai M, Amaya KE, Ross MG, Magee TR.

J Dev Orig Health Dis. 2011 Aug;2(4):226-35. doi: 10.1017/S2040174411000262.


In vitro cross-resistance to daptomycin and host defense cationic antimicrobial peptides in clinical methicillin-resistant Staphylococcus aureus isolates.

Mishra NN, McKinnell J, Yeaman MR, Rubio A, Nast CC, Chen L, Kreiswirth BN, Bayer AS.

Antimicrob Agents Chemother. 2011 Sep;55(9):4012-8. doi: 10.1128/AAC.00223-11. Epub 2011 Jun 27.


Hematopoietic growth factor inducible neurokinin-1 (Gpnmb/Osteoactivin) is a biomarker of progressive renal injury across species.

Patel-Chamberlin M, Wang Y, Satirapoj B, Phillips LM, Nast CC, Dai T, Watkins RA, Wu X, Natarajan R, Leng A, Ulanday K, Hirschberg RR, Lapage J, Nam EJ, Haq T, Adler SG.

Kidney Int. 2011 May;79(10):1138-48. doi: 10.1038/ki.2011.28. Epub 2011 Mar 9.


Maternal undernourished fetal kidneys exhibit differential regulation of nephrogenic genes including downregulation of the Notch signaling pathway.

Magee TR, Tafti SA, Desai M, Liu Q, Ross MG, Nast CC.

Reprod Sci. 2011 Jun;18(6):563-76. doi: 10.1177/1933719110393025. Epub 2011 Jan 27.


Carotenoid-related alteration of cell membrane fluidity impacts Staphylococcus aureus susceptibility to host defense peptides.

Mishra NN, Liu GY, Yeaman MR, Nast CC, Proctor RA, McKinnell J, Bayer AS.

Antimicrob Agents Chemother. 2011 Feb;55(2):526-31. doi: 10.1128/AAC.00680-10. Epub 2010 Nov 29.


Resolution of clinical and pathologic features of C1q nephropathy after rituximab therapy.

Sinha A, Nast CC, Hristea I, Vo AA, Jordan SC.

Clin Exp Nephrol. 2011 Feb;15(1):164-70. doi: 10.1007/s10157-010-0377-x. Epub 2010 Nov 25.


Cell wall thickening is not a universal accompaniment of the daptomycin nonsusceptibility phenotype in Staphylococcus aureus: evidence for multiple resistance mechanisms.

Yang SJ, Nast CC, Mishra NN, Yeaman MR, Fey PD, Bayer AS.

Antimicrob Agents Chemother. 2010 Aug;54(8):3079-85. doi: 10.1128/AAC.00122-10. Epub 2010 May 24.


Examination of association with candidate genes for diabetic nephropathy in a Mexican American population.

Kim S, Abboud HE, Pahl MV, Tayek J, Snyder S, Tamkin J, Alcorn H Jr, Ipp E, Nast CC, Elston RC, Iyengar SK, Adler SG.

Clin J Am Soc Nephrol. 2010 Jun;5(6):1072-8. doi: 10.2215/CJN.06550909. Epub 2010 Mar 18.


GDNF and MAPK-ERK pathway signaling is reduced during nephrogenesis following maternal under-nutrition.

Henry TQ, Mansano RZ, Nast CC, Lakshmanan J, Abdallah M, Abdel-Hakeem AK, Desai M, Ross MG, Magee TR.

J Dev Orig Health Dis. 2010 Feb;1(1):67-74. doi: 10.1017/S2040174409990134.


Analysis of cell membrane characteristics of in vitro-selected daptomycin-resistant strains of methicillin-resistant Staphylococcus aureus.

Mishra NN, Yang SJ, Sawa A, Rubio A, Nast CC, Yeaman MR, Bayer AS.

Antimicrob Agents Chemother. 2009 Jun;53(6):2312-8. doi: 10.1128/AAC.01682-08. Epub 2009 Mar 30.


Heat shock protein 27 overexpression mitigates cytokine-induced islet apoptosis and streptozotocin-induced diabetes.

Dai T, Patel-Chamberlin M, Natarajan R, Todorov I, Ma J, LaPage J, Phillips L, Nast CC, Becerra D, Chuang P, Tong L, de Belleroche J, Wells DJ, Wang Y, Adler SG.

Endocrinology. 2009 Jul;150(7):3031-9. doi: 10.1210/en.2008-0732. Epub 2009 Mar 26.


Nodular glomerulosclerosis in a patient with metabolic syndrome without diabetes.

Souraty P, Nast CC, Mehrotra R, Barba L, Martina J, Adler SG.

Nat Clin Pract Nephrol. 2008 Nov;4(11):639-42. doi: 10.1038/ncpneph0946. Epub 2008 Sep 16.


Mechanisms of impaired nephrogenesis with fetal growth restriction: altered renal transcription and growth factor expression.

Abdel-Hakeem AK, Henry TQ, Magee TR, Desai M, Ross MG, Mansano RZ, Torday JS, Nast CC.

Am J Obstet Gynecol. 2008 Sep;199(3):252.e1-7. doi: 10.1016/j.ajog.2008.05.018. Epub 2008 Jul 17.


Anti-glomerular basement membrane disease in an HIV-infected patient.

Wechsler E, Yang T, Jordan SC, Vo A, Nast CC.

Nat Clin Pract Nephrol. 2008 Mar;4(3):167-71. doi: 10.1038/ncpneph0724. Epub 2008 Jan 22.


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