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Items: 37

1.

Mice lacking Kcns1 in peripheral neurons show increased basal and neuropathic pain sensitivity.

Tsantoulas C, Denk F, Signore M, Nassar MA, Futai K, McMahon SB.

Pain. 2018 Aug;159(8):1641-1651. doi: 10.1097/j.pain.0000000000001255.

2.

NaV1.7 and pain: contribution of peripheral nerves.

Hoffmann T, Sharon O, Wittmann J, Carr RW, Vyshnevska A, Col R, Nassar MA, Reeh PW, Weidner C.

Pain. 2018 Mar;159(3):496-506. doi: 10.1097/j.pain.0000000000001119.

PMID:
29194125
3.

Veratridine produces distinct calcium response profiles in mouse Dorsal Root Ganglia neurons.

Mohammed ZA, Doran C, Grundy D, Nassar MA.

Sci Rep. 2017 Mar 24;7:45221. doi: 10.1038/srep45221.

4.

Reduced excitability and impaired nociception in peripheral unmyelinated fibers from Nav1.9-null mice.

Hoffmann T, Kistner K, Carr RW, Nassar MA, Reeh PW, Weidner C.

Pain. 2017 Jan;158(1):58-67.

PMID:
27780178
5.

Riluzole mediates anti-tumor properties in breast cancer cells independent of metabotropic glutamate receptor-1.

Speyer CL, Nassar MA, Hachem AH, Bukhsh MA, Jafry WS, Khansa RM, Gorski DH.

Breast Cancer Res Treat. 2016 Jun;157(2):217-228. doi: 10.1007/s10549-016-3816-x. Epub 2016 May 4.

PMID:
27146584
6.

Analgesic Effects of GpTx-1, PF-04856264 and CNV1014802 in a Mouse Model of NaV1.7-Mediated Pain.

Deuis JR, Wingerd JS, Winter Z, Durek T, Dekan Z, Sousa SR, Zimmermann K, Hoffmann T, Weidner C, Nassar MA, Alewood PF, Lewis RJ, Vetter I.

Toxins (Basel). 2016 Mar 17;8(3). pii: E78. doi: 10.3390/toxins8030078.

7.

Tamoxifen induces cellular stress in the nervous system by inhibiting cholesterol synthesis.

Denk F, Ramer LM, Erskine EL, Nassar MA, Bogdanov Y, Signore M, Wood JN, McMahon SB, Ramer MS.

Acta Neuropathol Commun. 2015 Nov 26;3:74. doi: 10.1186/s40478-015-0255-6.

8.

Mouse DRG Cell Line with Properties of Nociceptors.

Doran C, Chetrit J, Holley MC, Grundy D, Nassar MA.

PLoS One. 2015 Jun 8;10(6):e0128670. doi: 10.1371/journal.pone.0128670. eCollection 2015.

9.

Na+ current properties in islet α- and β-cells reflect cell-specific Scn3a and Scn9a expression.

Zhang Q, Chibalina MV, Bengtsson M, Groschner LN, Ramracheya R, Rorsman NJ, Leiss V, Nassar MA, Welling A, Gribble FM, Reimann F, Hofmann F, Wood JN, Ashcroft FM, Rorsman P.

J Physiol. 2014 Nov 1;592(21):4677-96. doi: 10.1113/jphysiol.2014.274209. Epub 2014 Aug 28.

10.

Multiple roles for NaV1.9 in the activation of visceral afferents by noxious inflammatory, mechanical, and human disease-derived stimuli.

Hockley JR, Boundouki G, Cibert-Goton V, McGuire C, Yip PK, Chan C, Tranter M, Wood JN, Nassar MA, Blackshaw LA, Aziz Q, Michael GJ, Baker MD, Winchester WJ, Knowles CH, Bulmer DC.

Pain. 2014 Oct;155(10):1962-75. doi: 10.1016/j.pain.2014.06.015. Epub 2014 Jun 24.

11.

Pain without nociceptors? Nav1.7-independent pain mechanisms.

Minett MS, Falk S, Santana-Varela S, Bogdanov YD, Nassar MA, Heegaard AM, Wood JN.

Cell Rep. 2014 Jan 30;6(2):301-12. doi: 10.1016/j.celrep.2013.12.033. Epub 2014 Jan 16.

12.

Time-dependent morphological and biochemical changes following cutaneous thermal burn injury and their modulation by copper nicotinate complex: an animal model.

Nassar MA, Eldien HM, Tawab HS, Saleem TH, Omar HM, Nassar AY, Hussein MR.

Ultrastruct Pathol. 2012 Oct;36(5):343-55. doi: 10.3109/01913123.2012.685687.

PMID:
23025652
13.

Mechanical and antibacterial properties of recycled carton paper coated by PS/Ag nanocomposites for packaging.

Nassar MA, Youssef AM.

Carbohydr Polym. 2012 Jun 5;89(1):269-74. doi: 10.1016/j.carbpol.2012.03.007. Epub 2012 Mar 8.

PMID:
24750633
14.

Role of Na(v)1.9 in activity-dependent axon growth in motoneurons.

Subramanian N, Wetzel A, Dombert B, Yadav P, Havlicek S, Jablonka S, Nassar MA, Blum R, Sendtner M.

Hum Mol Genet. 2012 Aug 15;21(16):3655-67. doi: 10.1093/hmg/dds195. Epub 2012 May 28.

PMID:
22641814
15.

Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons.

Minett MS, Nassar MA, Clark AK, Passmore G, Dickenson AH, Wang F, Malcangio M, Wood JN.

Nat Commun. 2012 Apr 24;3:791. doi: 10.1038/ncomms1795.

16.

Sodium channels and mammalian sensory mechanotransduction.

Raouf R, Rugiero F, Kiesewetter H, Hatch R, Hummler E, Nassar MA, Wang F, Wood JN.

Mol Pain. 2012 Mar 26;8:21. doi: 10.1186/1744-8069-8-21.

17.

Genetic ablation of delta opioid receptors in nociceptive sensory neurons increases chronic pain and abolishes opioid analgesia.

Gaveriaux-Ruff C, Nozaki C, Nadal X, Hever XC, Weibel R, Matifas A, Reiss D, Filliol D, Nassar MA, Wood JN, Maldonado R, Kieffer BL.

Pain. 2011 Jun;152(6):1238-48. doi: 10.1016/j.pain.2010.12.031. Epub 2011 Feb 3.

PMID:
21295407
18.

Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain.

Zhao J, Yuan G, Cendan CM, Nassar MA, Lagerström MC, Kullander K, Gavazzi I, Wood JN.

Mol Pain. 2010 Nov 8;6:77. doi: 10.1186/1744-8069-6-77.

19.

Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.

Zhao J, Lee MC, Momin A, Cendan CM, Shepherd ST, Baker MD, Asante C, Bee L, Bethry A, Perkins JR, Nassar MA, Abrahamsen B, Dickenson A, Cobb BS, Merkenschlager M, Wood JN.

J Neurosci. 2010 Aug 11;30(32):10860-71. doi: 10.1523/JNEUROSCI.1980-10.2010.

20.

RET signaling is required for survival and normal function of nonpeptidergic nociceptors.

Golden JP, Hoshi M, Nassar MA, Enomoto H, Wood JN, Milbrandt J, Gereau RW 4th, Johnson EM Jr, Jain S.

J Neurosci. 2010 Mar 17;30(11):3983-94. doi: 10.1523/JNEUROSCI.5930-09.2010.

21.

GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain.

Eijkelkamp N, Heijnen CJ, Willemen HL, Deumens R, Joosten EA, Kleibeuker W, den Hartog IJ, van Velthoven CT, Nijboer C, Nassar MA, Dorn GW 2nd, Wood JN, Kavelaars A.

J Neurosci. 2010 Feb 10;30(6):2138-49. doi: 10.1523/JNEUROSCI.5752-09.2010.

22.

Behavioral deficits and subregion-specific suppression of LTP in mice expressing a population of mutant NMDA receptors throughout the hippocampus.

Chen PE, Errington ML, Kneussel M, Chen G, Annala AJ, Rudhard YH, Rast GF, Specht CG, Tigaret CM, Nassar MA, Morris RG, Bliss TV, Schoepfer R.

Learn Mem. 2009 Sep 30;16(10):635-44. doi: 10.1101/lm.1316909. Print 2009 Oct.

23.

Sensory axon-derived neuregulin-1 is required for axoglial signaling and normal sensory function but not for long-term axon maintenance.

Fricker FR, Zhu N, Tsantoulas C, Abrahamsen B, Nassar MA, Thakur M, Garratt AN, Birchmeier C, McMahon SB, Wood JN, Bennett DL.

J Neurosci. 2009 Jun 17;29(24):7667-78. doi: 10.1523/JNEUROSCI.6053-08.2009.

24.

New insights into the roles of dendritic cells in intestinal immunity and tolerance.

Cerovic V, McDonald V, Nassar MA, Paulin SM, Macpherson GG, Milling SW.

Int Rev Cell Mol Biol. 2009;272:33-105. doi: 10.1016/S1937-6448(08)01602-X. Review.

PMID:
19121816
25.

The cell and molecular basis of mechanical, cold, and inflammatory pain.

Abrahamsen B, Zhao J, Asante CO, Cendan CM, Marsh S, Martinez-Barbera JP, Nassar MA, Dickenson AH, Wood JN.

Science. 2008 Aug 1;321(5889):702-5. doi: 10.1126/science.1156916.

26.

GTP up-regulated persistent Na+ current and enhanced nociceptor excitability require NaV1.9.

Ostman JA, Nassar MA, Wood JN, Baker MD.

J Physiol. 2008 Feb 15;586(4):1077-87. Epub 2007 Dec 20.

27.

Nerve injury induces robust allodynia and ectopic discharges in Nav1.3 null mutant mice.

Nassar MA, Baker MD, Levato A, Ingram R, Mallucci G, McMahon SB, Wood JN.

Mol Pain. 2006 Oct 19;2:33.

28.

Deletion of annexin 2 light chain p11 in nociceptors causes deficits in somatosensory coding and pain behavior.

Foulkes T, Nassar MA, Lane T, Matthews EA, Baker MD, Gerke V, Okuse K, Dickenson AH, Wood JN.

J Neurosci. 2006 Oct 11;26(41):10499-507.

29.

Tamoxifen-inducible NaV1.8-CreERT2 recombinase activity in nociceptive neurons of dorsal root ganglia.

Zhao J, Nassar MA, Gavazzi I, Wood JN.

Genesis. 2006 Aug;44(8):364-71.

PMID:
16850455
30.

Nociceptor-derived brain-derived neurotrophic factor regulates acute and inflammatory but not neuropathic pain.

Zhao J, Seereeram A, Nassar MA, Levato A, Pezet S, Hathaway G, Morenilla-Palao C, Stirling C, Fitzgerald M, McMahon SB, Rios M, Wood JN; London Pain Consortium.

Mol Cell Neurosci. 2006 Mar;31(3):539-48. Epub 2006 Jan 18.

PMID:
16413788
31.

Parallel "pain" pathways arise from subpopulations of primary afferent nociceptor.

Braz JM, Nassar MA, Wood JN, Basbaum AI.

Neuron. 2005 Sep 15;47(6):787-93.

32.

Neuropathic pain develops normally in mice lacking both Na(v)1.7 and Na(v)1.8.

Nassar MA, Levato A, Stirling LC, Wood JN.

Mol Pain. 2005 Aug 22;1:24.

33.

Nociceptor-specific gene deletion using heterozygous NaV1.8-Cre recombinase mice.

Stirling LC, Forlani G, Baker MD, Wood JN, Matthews EA, Dickenson AH, Nassar MA.

Pain. 2005 Jan;113(1-2):27-36.

PMID:
15621361
34.

Ion channel activities implicated in pathological pain.

Wood JN, Abrahamsen B, Baker MD, Boorman JD, Donier E, Drew LJ, Nassar MA, Okuse K, Seereeram A, Stirling CL, Zhao J.

Novartis Found Symp. 2004;261:32-40; discussion 40-54.

PMID:
15469043
35.

Nociceptor-specific gene deletion reveals a major role for Nav1.7 (PN1) in acute and inflammatory pain.

Nassar MA, Stirling LC, Forlani G, Baker MD, Matthews EA, Dickenson AH, Wood JN.

Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12706-11. Epub 2004 Aug 16.

36.

Absence of Whisker-related pattern formation in mice with NMDA receptors lacking coincidence detection properties and calcium signaling.

Rudhard Y, Kneussel M, Nassar MA, Rast GF, Annala AJ, Chen PE, Tigaret CM, Dean I, Roes J, Gibb AJ, Hunt SP, Schoepfer R.

J Neurosci. 2003 Mar 15;23(6):2323-32.

37.

Recombinant nicotinic receptors, expressed in Xenopus oocytes, do not resemble native rat sympathetic ganglion receptors in single-channel behaviour.

Sivilotti LG, McNeil DK, Lewis TM, Nassar MA, Schoepfer R, Colquhoun D.

J Physiol. 1997 Apr 1;500 ( Pt 1):123-38.

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