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Items: 1 to 50 of 73

1.

ATPase activity of human binding immunoglobulin protein (BiP) variants is enhanced by signal sequence and physiological concentrations of Mn2.

Bandla S, Diaz S, Nasheuer HP, FitzGerald U.

FEBS Open Bio. 2019 Aug;9(8):1355-1369. doi: 10.1002/2211-5463.12645. Epub 2019 Jul 10.

2.

Optimizing fluorescent protein expression for quantitative fluorescence microscopy and spectroscopy using herpes simplex thymidine kinase promoter sequences.

Ali R, Ramadurai S, Barry F, Nasheuer HP.

FEBS Open Bio. 2018 May 8;8(6):1043-1060. doi: 10.1002/2211-5463.12432. eCollection 2018 Jun.

3.

Interplay of DNA damage and cell cycle signaling at the level of human replication protein A.

Borgstahl GE, Brader K, Mosel A, Liu S, Kremmer E, Goettsch KA, Kolar C, Nasheuer HP, Oakley GG.

DNA Repair (Amst). 2014 Sep;21:12-23. doi: 10.1016/j.dnarep.2014.05.005. Epub 2014 Jun 13.

4.

PARG is dispensable for recovery from transient replicative stress but required to prevent detrimental accumulation of poly(ADP-ribose) upon prolonged replicative stress.

Illuzzi G, Fouquerel E, Amé JC, Noll A, Rehmet K, Nasheuer HP, Dantzer F, Schreiber V.

Nucleic Acids Res. 2014 Jul;42(12):7776-92. doi: 10.1093/nar/gku505. Epub 2014 Jun 6.

5.

Basic fibroblast growth factor modifies the hypoxic response of human bone marrow stromal cells by ERK-mediated enhancement of HIF-1α activity.

Fábián Z, Ramadurai S, Shaw G, Nasheuer HP, Kolch W, Taylor C, Barry F.

Stem Cell Res. 2014 May;12(3):646-58. doi: 10.1016/j.scr.2014.02.007. Epub 2014 Mar 6.

6.

Cell cycle-dependent formation of Cdc45-Claspin complexes in human cells is compromized by UV-mediated DNA damage.

Broderick R, Rainey MD, Santocanale C, Nasheuer HP.

FEBS J. 2013 Oct;280(19):4888-902. doi: 10.1111/febs.12465. Epub 2013 Aug 27.

7.

Segregation of replicative DNA polymerases during S phase: DNA polymerase ε, but not DNA polymerases α/δ, are associated with lamins throughout S phase in human cells.

Vaara M, Itkonen H, Hillukkala T, Liu Z, Nasheuer HP, Schaarschmidt D, Pospiech H, Syväoja JE.

J Biol Chem. 2012 Sep 28;287(40):33327-38. Epub 2012 Aug 10.

8.

Cell cycle-dependent mobility of Cdc45 determined in vivo by fluorescence correlation spectroscopy.

Broderick R, Ramadurai S, Tóth K, Togashi DM, Ryder AG, Langowski J, Nasheuer HP.

PLoS One. 2012;7(4):e35537. doi: 10.1371/journal.pone.0035537. Epub 2012 Apr 19.

9.

Stimulation of BK virus DNA replication by NFI family transcription factors.

Liang B, Tikhanovich I, Nasheuer HP, Folk WR.

J Virol. 2012 Mar;86(6):3264-75. doi: 10.1128/JVI.06369-11. Epub 2011 Dec 28.

10.

Modification of histones by sugar β-N-acetylglucosamine (GlcNAc) occurs on multiple residues, including histone H3 serine 10, and is cell cycle-regulated.

Zhang S, Roche K, Nasheuer HP, Lowndes NF.

J Biol Chem. 2011 Oct 28;286(43):37483-95. doi: 10.1074/jbc.M111.284885. Epub 2011 Sep 6.

11.

Inhibition of human BK polyomavirus replication by small noncoding RNAs.

Tikhanovich I, Liang B, Seoighe C, Folk WR, Nasheuer HP.

J Virol. 2011 Jul;85(14):6930-40. doi: 10.1128/JVI.00547-11. Epub 2011 May 4.

12.

Genome stability and human diseases. Preface.

Nasheuer HP.

Subcell Biochem. 2010;50:vii-viii. No abstract available.

PMID:
20419901
13.
14.

Integrated stoichiometric, thermodynamic and kinetic modelling of steady state metabolism.

Fleming RM, Thiele I, Provan G, Nasheuer HP.

J Theor Biol. 2010 Jun 7;264(3):683-92. doi: 10.1016/j.jtbi.2010.02.044. Epub 2010 Mar 15.

15.

The use of transgenic mice in cancer and genome stability research.

Conmy S, Nasheuer HP.

Subcell Biochem. 2010;50:325-36. doi: 10.1007/978-90-481-3471-7_17. Review.

PMID:
20012590
16.

Eukaryotic single-stranded DNA binding proteins: central factors in genome stability.

Broderick S, Rehmet K, Concannon C, Nasheuer HP.

Subcell Biochem. 2010;50:143-63. doi: 10.1007/978-90-481-3471-7_8. Review.

PMID:
20012581
17.

Quantitative assignment of reaction directionality in constraint-based models of metabolism: application to Escherichia coli.

Fleming RM, Thiele I, Nasheuer HP.

Biophys Chem. 2009 Dec;145(2-3):47-56. doi: 10.1016/j.bpc.2009.08.007. Epub 2009 Sep 1.

18.

Ionizing radiation-dependent and independent phosphorylation of the 32-kDa subunit of replication protein A during mitosis.

Stephan H, Concannon C, Kremmer E, Carty MP, Nasheuer HP.

Nucleic Acids Res. 2009 Oct;37(18):6028-41. doi: 10.1093/nar/gkp605. Epub 2009 Aug 11.

19.

Regulation of Cdc45 in the cell cycle and after DNA damage.

Broderick R, Nasheuer HP.

Biochem Soc Trans. 2009 Aug;37(Pt 4):926-30. doi: 10.1042/BST0370926. Review.

PMID:
19614620
20.

XRCC1 interacts with the p58 subunit of DNA Pol alpha-primase and may coordinate DNA repair and replication during S phase.

Lévy N, Oehlmann M, Delalande F, Nasheuer HP, Van Dorsselaer A, Schreiber V, de Murcia G, Ménissier-de Murcia J, Maiorano D, Bresson A.

Nucleic Acids Res. 2009 Jun;37(10):3177-88. doi: 10.1093/nar/gkp144. Epub 2009 Mar 21.

21.

Restriction of human polyomavirus BK virus DNA replication in murine cells and extracts.

Mahon C, Liang B, Tikhanovich I, Abend JR, Imperiale MJ, Nasheuer HP, Folk WR.

J Virol. 2009 Jun;83(11):5708-17. doi: 10.1128/JVI.00300-09. Epub 2009 Mar 18.

22.

Comparison of DNA replication in Xenopus laevis and Simian Virus 40.

Oehlmann M, Mahon C, Nasheuer HP.

Adv Exp Med Biol. 2007;604:3-16. Review.

PMID:
17695718
23.

Different activities of the largest subunit of replication protein A cooperate during SV40 DNA replication.

Taneja P, Boche I, Hartmann H, Nasheuer HP, Grosse F, Fanning E, Weisshart K.

FEBS Lett. 2007 Aug 21;581(21):3973-8. Epub 2007 Jul 25.

24.

Timed interactions between viral and cellular replication factors during the initiation of SV40 in vitro DNA replication.

Taneja P, Nasheuer HP, Hartmann H, Grosse F, Fanning E, Weisshart K.

Biochem J. 2007 Oct 15;407(2):313-20.

25.

Human Cdc45 is a proliferation-associated antigen.

Pollok S, Bauerschmidt C, Sänger J, Nasheuer HP, Grosse F.

FEBS J. 2007 Jul;274(14):3669-3684. doi: 10.1111/j.1742-4658.2007.05900.x. Epub 2007 Jul 3.

26.

Interactions of human Cdc45 with the Mcm2-7 complex, the GINS complex, and DNA polymerases delta and epsilon during S phase.

Bauerschmidt C, Pollok S, Kremmer E, Nasheuer HP, Grosse F.

Genes Cells. 2007 Jun;12(6):745-58.

27.

Mobility and distribution of replication protein A in living cells using fluorescence correlation spectroscopy.

Braet C, Stephan H, Dobbie IM, Togashi DM, Ryder AG, Földes-Papp Z, Lowndes N, Nasheuer HP.

Exp Mol Pathol. 2007 Apr;82(2):156-62. Epub 2007 Jan 12.

PMID:
17303118
28.

DNA polymerase epsilon associates with the elongating form of RNA polymerase II and nascent transcripts.

Rytkönen AK, Hillukkala T, Vaara M, Sokka M, Jokela M, Sormunen R, Nasheuer HP, Nethanel T, Kaufmann G, Pospiech H, Syväoja JE.

FEBS J. 2006 Dec;273(24):5535-49.

29.

The Chk1-mediated S-phase checkpoint targets initiation factor Cdc45 via a Cdc25A/Cdk2-independent mechanism.

Liu P, Barkley LR, Day T, Bi X, Slater DM, Alexandrow MG, Nasheuer HP, Vaziri C.

J Biol Chem. 2006 Oct 13;281(41):30631-44. Epub 2006 Aug 15.

30.

Distinctive activities of DNA polymerases during human DNA replication.

Rytkönen AK, Vaara M, Nethanel T, Kaufmann G, Sormunen R, Läärä E, Nasheuer HP, Rahmeh A, Lee MY, Syväoja JE, Pospiech H.

FEBS J. 2006 Jul;273(13):2984-3001. Epub 2006 Jun 7.

31.

Physical and functional modularity of the protein network in yeast.

Wilhelm T, Nasheuer HP, Huang S.

Mol Cell Proteomics. 2003 May;2(5):292-8.

32.

Post-transcriptional expression regulation in the yeast Saccharomyces cerevisiae on a genomic scale.

Beyer A, Hollunder J, Nasheuer HP, Wilhelm T.

Mol Cell Proteomics. 2004 Nov;3(11):1083-92. Epub 2004 Aug 23.

33.

Partial proteolysis of simian virus 40 T antigen reveals intramolecular contacts between domains and conformation changes upon hexamer assembly.

Weisshart K, Friedl S, Taneja P, Nasheuer HP, Schlott B, Grosse F, Fanning E.

J Biol Chem. 2004 Sep 10;279(37):38943-51. Epub 2004 Jul 9.

34.

Coordinated regulation of replication protein A activities by its subunits p14 and p32.

Weisshart K, Pestryakov P, Smith RW, Hartmann H, Kremmer E, Lavrik O, Nasheuer HP.

J Biol Chem. 2004 Aug 20;279(34):35368-76. Epub 2004 Jun 17.

35.
36.

Human replication protein A. The C-terminal RPA70 and the central RPA32 domains are involved in the interactions with the 3'-end of a primer-template DNA.

Pestryakov PE, Weisshart K, Schlott B, Khodyreva SN, Kremmer E, Grosse F, Lavrik OI, Nasheuer HP.

J Biol Chem. 2003 May 9;278(19):17515-24. Epub 2003 Feb 24.

37.

Regulation of eukaryotic DNA replication at the initiation step.

Pollok S, Stoepel J, Bauerschmidt C, Kremmer E, Nasheuer HP.

Biochem Soc Trans. 2003 Feb;31(Pt 1):266-9. Review.

PMID:
12546699
39.

Initiation of eukaryotic DNA replication: regulation and mechanisms.

Nasheuer HP, Smith R, Bauerschmidt C, Grosse F, Weisshart K.

Prog Nucleic Acid Res Mol Biol. 2002;72:41-94. Review.

PMID:
12206458
40.

Species specificity of simian virus 40 DNA replication in vitro requires multiple functions of human DNA polymerase alpha.

Smith RW, Steffen C, Grosse F, Nasheuer HP.

J Biol Chem. 2002 Jun 7;277(23):20541-8. Epub 2002 Apr 1.

41.
43.

Multiple phosphorylation sites of DNA polymerase alpha-primase cooperate to regulate the initiation of DNA replication in vitro.

Schub O, Rohaly G, Smith RW, Schneider A, Dehde S, Dornreiter I, Nasheuer HP.

J Biol Chem. 2001 Oct 12;276(41):38076-83. Epub 2001 Aug 13.

44.

A human topoisomerase I cleavage complex is recognized by an additional human topisomerase I molecule in vitro.

Søe K, Dianov G, Nasheuer HP, Bohr VA, Grosse F, Stevnsner T.

Nucleic Acids Res. 2001 Aug 1;29(15):3195-203.

45.

Two immunologically distinct human DNA polymerase alpha-primase subpopulations are involved in cellular DNA replication.

Dehde S, Rohaly G, Schub O, Nasheuer HP, Bohn W, Chemnitz J, Deppert W, Dornreiter I.

Mol Cell Biol. 2001 Apr;21(7):2581-93.

46.

Different regions of primase subunit p48 control mouse polyomavirus and simian virus 40 DNA replication in vitro.

Kautz AR, Schneider A, Weisshart K, Geiger C, Nasheuer HP.

J Virol. 2001 Feb;75(4):1751-60.

47.

Synthesis of base-substituted dUTP analogues carrying a photoreactive group and their application to study human replication protein A.

Kolpashchikov DM, Ivanova TM, Boghachev VS, Nasheuer HP, Weisshart K, Favre A, Pestryakov PE, Lavrik OI.

Bioconjug Chem. 2000 Jul-Aug;11(4):445-51.

PMID:
10898564
48.
49.

Eukaryotic DNA polymerases, a growing family.

Hübscher U, Nasheuer HP, Syväoja JE.

Trends Biochem Sci. 2000 Mar;25(3):143-7. Review.

PMID:
10694886
50.

RPA subunit arrangement near the 3'-end of the primer is modulated by the length of the template strand and cooperative protein interactions.

Lavrik OI, Kolpashchikov DM, Weisshart K, Nasheuer HP, Khodyreva SN, Favre A.

Nucleic Acids Res. 1999 Nov 1;27(21):4235-40.

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