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Items: 19

1.

Discovery of selective nonpeptidergic neuropeptide FF2 receptor agonists.

Gaubert G, Bertozzi F, Kelly NM, Pawlas J, Scully AL, Nash NR, Gardell LR, Lameh J, Olsson R.

J Med Chem. 2009 Nov 12;52(21):6511-4. doi: 10.1021/jm9011998.

PMID:
19803524
2.

Identification and characterization of novel small-molecule protease-activated receptor 2 agonists.

Gardell LR, Ma JN, Seitzberg JG, Knapp AE, Schiffer HH, Tabatabaei A, Davis CN, Owens M, Clemons B, Wong KK, Lund B, Nash NR, Gao Y, Lameh J, Schmelzer K, Olsson R, Burstein ES.

J Pharmacol Exp Ther. 2008 Dec;327(3):799-808. doi: 10.1124/jpet.108.142570. Epub 2008 Sep 3.

PMID:
18768780
3.

Identification of novel selective V2 receptor non-peptide agonists.

Del Tredici AL, Vanover KE, Knapp AE, Bertozzi SM, Nash NR, Burstein ES, Lameh J, Currier EA, Davis RE, Brann MR, Mohell N, Olsson R, Piu F.

Biochem Pharmacol. 2008 Oct 30;76(9):1134-41. doi: 10.1016/j.bcp.2008.08.004. Epub 2008 Aug 12.

PMID:
18761325
4.

Monitoring interactions between receptor tyrosine kinases and their downstream effector proteins in living cells using bioluminescence resonance energy transfer.

Tan PK, Wang J, Littler PL, Wong KK, Sweetnam TA, Keefe W, Nash NR, Reding EC, Piu F, Brann MR, Schiffer HH.

Mol Pharmacol. 2007 Dec;72(6):1440-6. Epub 2007 Aug 22.

PMID:
17715395
5.

Identification of the atypical L-type Ca2+ channel blocker diltiazem and its metabolites as ghrelin receptor agonists.

Ma JN, Schiffer HH, Knapp AE, Wang J, Wong KK, Currier EA, Owens M, Nash NR, Gardell LR, Brann MR, Olsson R, Burstein ES.

Mol Pharmacol. 2007 Aug;72(2):380-6. Epub 2007 May 2.

PMID:
17475811
6.

Pharmacology and signaling properties of epidermal growth factor receptor isoforms studied by bioluminescence resonance energy transfer.

Schiffer HH, Reding EC, Fuhs SR, Lu Q, Piu F, Wong S, Littler PL, Weiner DM, Keefe W, Tan PK, Nash NR, Knapp AE, Olsson R, Brann MR.

Mol Pharmacol. 2007 Feb;71(2):508-18. Epub 2006 Sep 12.

PMID:
16968809
7.

Integrative functional assays, chemical genomics and high throughput screening: harnessing signal transduction pathways to a common HTS readout.

Burstein ES, Piu F, Ma JN, Weissman JT, Currier EA, Nash NR, Weiner DM, Spalding TA, Schiffer HH, Del Tredici AL, Brann MR.

Curr Pharm Des. 2006;12(14):1717-29.

PMID:
16712484
8.

Characterization of the Mas-related gene family: structural and functional conservation of human and rhesus MrgX receptors.

Burstein ES, Ott TR, Feddock M, Ma JN, Fuhs S, Wong S, Schiffer HH, Brann MR, Nash NR.

Br J Pharmacol. 2006 Jan;147(1):73-82.

9.

Intrinsic efficacy of antipsychotics at human D2, D3, and D4 dopamine receptors: identification of the clozapine metabolite N-desmethylclozapine as a D2/D3 partial agonist.

Burstein ES, Ma J, Wong S, Gao Y, Pham E, Knapp AE, Nash NR, Olsson R, Davis RE, Hacksell U, Weiner DM, Brann MR.

J Pharmacol Exp Ther. 2005 Dec;315(3):1278-87. Epub 2005 Aug 31.

PMID:
16135699
10.

Functional screening of drug target genes: m1 muscarinic acetylcholine receptor phenotypes in degenerative dementias.

Weiner DM, Goodman MW, Colpitts TM, Feddock MA, Duggento KL, Nash NR, Levey AI, Brann MR.

Am J Pharmacogenomics. 2004;4(2):119-28.

PMID:
15059034
11.

Discovery of novel peptide/receptor interactions: identification of PHM-27 as a potent agonist of the human calcitonin receptor.

Ma JN, Currier EA, Essex A, Feddock M, Spalding TA, Nash NR, Brann MR, Burstein ES.

Biochem Pharmacol. 2004 Apr 1;67(7):1279-84.

PMID:
15013843
12.

Molecular cloning and pharmacology of functionally distinct isoforms of the human histamine H(3) receptor.

Wellendorph P, Goodman MW, Burstein ES, Nash NR, Brann MR, Weiner DM.

Neuropharmacology. 2002 Jun;42(7):929-40.

PMID:
12069903
13.

Very early activation of m-calpain in peripheral nerve during Wallerian degeneration.

Glass JD, Culver DG, Levey AI, Nash NR.

J Neurol Sci. 2002 Apr 15;196(1-2):9-20.

PMID:
11959150
14.

Cloning and localization of exon 5-containing isoforms of the NMDAR1 subunit in human and rat brains.

Nash NR, Heilman CJ, Rees HD, Levey AI.

J Neurochem. 1997 Aug;69(2):485-93.

15.

Presenilin-1 protein expression in familial and sporadic Alzheimer's disease.

Levey AI, Heilman CJ, Lah JJ, Nash NR, Rees HD, Wakai M, Mirra SS, Rye DB, Nochlin D, Bird TD, Mufson EJ.

Ann Neurol. 1997 Jun;41(6):742-53.

PMID:
9189035
16.

Light and electron microscopic localization of presenilin-1 in primate brain.

Lah JJ, Heilman CJ, Nash NR, Rees HD, Yi H, Counts SE, Levey AI.

J Neurosci. 1997 Mar 15;17(6):1971-80.

17.

The N terminus of bradykinin when bound to the human bradykinin B2 receptor is adjacent to extracellular Cys20 and Cys277 in the receptor.

Herzig MC, Nash NR, Connolly M, Kyle DJ, Leeb-Lundberg LM.

J Biol Chem. 1996 Nov 22;271(47):29746-51.

18.

Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles.

Gilmor ML, Nash NR, Roghani A, Edwards RH, Yi H, Hersch SM, Levey AI.

J Neurosci. 1996 Apr 1;16(7):2179-90.

19.

Identification and localization of huntingtin in brain and human lymphoblastoid cell lines with anti-fusion protein antibodies.

Gutekunst CA, Levey AI, Heilman CJ, Whaley WL, Yi H, Nash NR, Rees HD, Madden JJ, Hersch SM.

Proc Natl Acad Sci U S A. 1995 Sep 12;92(19):8710-4.

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