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Items: 1 to 50 of 223


Ability of Platelet-Derived Extracellular Vesicles to Promote Neutrophil-Endothelial Cell Interactions.

Kuravi SJ, Harrison P, Rainger GE, Nash GB.

Inflammation. 2018 Sep 14. doi: 10.1007/s10753-018-0893-5. [Epub ahead of print]


Signalling through Src family kinase isoforms is not redundant in models of thrombo-inflammatory vascular disease.

Harrison MJ, Chimen M, Hussain M, Iqbal AJ, Senis YA, Nash GB, Watson SP, Rainger GE.

J Cell Mol Med. 2018 Sep;22(9):4317-4327. doi: 10.1111/jcmm.13721. Epub 2018 Jul 4.


Origin-Specific Adhesive Interactions of Mesenchymal Stem Cells with Platelets Influence Their Behavior After Infusion.

Sheriff L, Alanazi A, Ward LSC, Ward C, Munir H, Rayes J, Alassiri M, Watson SP, Newsome PN, Rainger GE, Kalia N, Frampton J, McGettrick HM, Nash GB.

Stem Cells. 2018 Jul;36(7):1062-1074. doi: 10.1002/stem.2811. Epub 2018 Mar 23.


The Relationship Between Serum Interleukin-1α and Asymptomatic Infrarenal Abdominal Aortic Aneurysm Size, Morphology, and Growth Rates.

Ahmad M, Kuravi S, Hodson J, Rainger GE, Nash GB, Vohra RK, Bradbury AW.

Eur J Vasc Endovasc Surg. 2018 Jul;56(1):130-135. doi: 10.1016/j.ejvs.2018.01.015. Epub 2018 Feb 16.


Tailoring iridium luminescence and gold nanoparticle size for imaging of microvascular blood flow.

Rogers NJ, Jeffery HC, Claire S, Lewis DJ, Zikeli G, Hodges NJ, Egginton S, Nash GB, Pikramenou Z.

Nanomedicine (Lond). 2017 Nov;12(22):2725-2740. doi: 10.2217/nnm-2017-0211. Epub 2017 Sep 29.


Identification of a transitional fibroblast function in very early rheumatoid arthritis.

Filer A, Ward LSC, Kemble S, Davies CS, Munir H, Rogers R, Raza K, Buckley CD, Nash GB, McGettrick HM.

Ann Rheum Dis. 2017 Dec;76(12):2105-2112. doi: 10.1136/annrheumdis-2017-211286. Epub 2017 Aug 28.


Changes in the pattern of plasma extracellular vesicles after severe trauma.

Kuravi SJ, Yates CM, Foster M, Harrison P, Hazeldine J, Hampson P, Watson C, Belli A, Midwinter M, Nash GB.

PLoS One. 2017 Aug 24;12(8):e0183640. doi: 10.1371/journal.pone.0183640. eCollection 2017.


Modulation of VEGF-induced migration and network formation by lymphatic endothelial cells: Roles of platelets and podoplanin.

Langan SA, Navarro-Núñez L, Watson SP, Nash GB.

Platelets. 2018 Jul;29(5):486-495. doi: 10.1080/09537104.2017.1336210. Epub 2017 Jul 20.


Bone morphogenetic protein 9 (BMP9) and BMP10 enhance tumor necrosis factor-α-induced monocyte recruitment to the vascular endothelium mainly via activin receptor-like kinase 2.

Mitrofan CG, Appleby SL, Nash GB, Mallat Z, Chilvers ER, Upton PD, Morrell NW.

J Biol Chem. 2017 Aug 18;292(33):13714-13726. doi: 10.1074/jbc.M117.778506. Epub 2017 Jun 23.


Adipogenic Differentiation of Mesenchymal Stem Cells Alters Their Immunomodulatory Properties in a Tissue-Specific Manner.

Munir H, Ward LSC, Sheriff L, Kemble S, Nayar S, Barone F, Nash GB, McGettrick HM.

Stem Cells. 2017 Jun;35(6):1636-1646. doi: 10.1002/stem.2622. Epub 2017 Apr 24.


Mesenchymal Stromal Cells as Active Regulators of Lymphocyte Recruitment to Blood Vascular Endothelial Cells.

Mcgettrick HM, Ward LS, Rainger GE, Nash GB.

Methods Mol Biol. 2017;1591:121-142. doi: 10.1007/978-1-4939-6931-9_9.


Monocyte Subsets Coregulate Inflammatory Responses by Integrated Signaling through TNF and IL-6 at the Endothelial Cell Interface.

Chimen M, Yates CM, McGettrick HM, Ward LS, Harrison MJ, Apta B, Dib LH, Imhof BA, Harrison P, Nash GB, Rainger GE.

J Immunol. 2017 Apr 1;198(7):2834-2843. doi: 10.4049/jimmunol.1601281. Epub 2017 Feb 13.


Bone Morphogenetic Protein 9 Enhances Lipopolysaccharide-Induced Leukocyte Recruitment to the Vascular Endothelium.

Appleby SL, Mitrofan CG, Crosby A, Hoenderdos K, Lodge K, Upton PD, Yates CM, Nash GB, Chilvers ER, Morrell NW.

J Immunol. 2016 Oct 15;197(8):3302-3314. doi: 10.4049/jimmunol.1601219. Epub 2016 Sep 19.


The Aminopeptidase CD13 Induces Homotypic Aggregation in Neutrophils and Impairs Collagen Invasion.

Fiddler CA, Parfrey H, Cowburn AS, Luo D, Nash GB, Murphy G, Chilvers ER.

PLoS One. 2016 Jul 28;11(7):e0160108. doi: 10.1371/journal.pone.0160108. eCollection 2016.


Static and Dynamic Assays of Cell Adhesion Relevant to the Vasculature.

Butler LM, McGettrick HM, Nash GB.

Methods Mol Biol. 2016;1430:231-48. doi: 10.1007/978-1-4939-3628-1_16.


Comparative Ability of Mesenchymal Stromal Cells from Different Tissues to Limit Neutrophil Recruitment to Inflamed Endothelium.

Munir H, Luu NT, Clarke LS, Nash GB, McGettrick HM.

PLoS One. 2016 May 12;11(5):e0155161. doi: 10.1371/journal.pone.0155161. eCollection 2016.


Effects of vessel size, cell sedimentation and haematocrit on the adhesion of leukocytes and platelets from flowing blood.

Watts T, Barigou M, Nash GB.

Biorheology. 2015;52(5-6):391-404. doi: 10.3233/BIR-15043.


The role of platelets in the recruitment of leukocytes during vascular disease.

Ed Rainger G, Chimen M, Harrison MJ, Yates CM, Harrison P, Watson SP, Lordkipanidzé M, Nash GB.

Platelets. 2015;26(6):507-20. doi: 10.3109/09537104.2015.1064881. Epub 2015 Jul 21. Review.


Platelet actin nodules are podosome-like structures dependent on Wiskott-Aldrich syndrome protein and ARP2/3 complex.

Poulter NS, Pollitt AY, Davies A, Malinova D, Nash GB, Hannon MJ, Pikramenou Z, Rappoport JZ, Hartwig JH, Owen DM, Thrasher AJ, Watson SP, Thomas SG.

Nat Commun. 2015 Jun 1;6:7254. doi: 10.1038/ncomms8254.


Homeostatic regulation of T cell trafficking by a B cell-derived peptide is impaired in autoimmune and chronic inflammatory disease.

Chimen M, McGettrick HM, Apta B, Kuravi SJ, Yates CM, Kennedy A, Odedra A, Alassiri M, Harrison M, Martin A, Barone F, Nayar S, Hitchcock JR, Cunningham AF, Raza K, Filer A, Copland DA, Dick AD, Robinson J, Kalia N, Walker LSK, Buckley CD, Nash GB, Narendran P, Rainger GE.

Nat Med. 2015 May;21(5):467-475. doi: 10.1038/nm.3842. Epub 2015 Apr 20.


The roles of integrins in function of human neutrophils after their migration through endothelium into interstitial matrix.

Luo D, McGettrick HM, Stone PC, Rainger GE, Nash GB.

PLoS One. 2015 Feb 23;10(2):e0118593. doi: 10.1371/journal.pone.0118593. eCollection 2015.


Platelet adhesion to podoplanin under flow is mediated by the receptor CLEC-2 and stabilised by Src/Syk-dependent platelet signalling.

Navarro-Núñez L, Pollitt AY, Lowe K, Latif A, Nash GB, Watson SP.

Thromb Haemost. 2015 May;113(5):1109-20. doi: 10.1160/TH14-09-0762. Epub 2015 Feb 19.


Analyzing the effects of stromal cells on the recruitment of leukocytes from flow.

Munir H, Rainger GE, Nash GB, McGettrick H.

J Vis Exp. 2015 Jan 7;(95):e52480. doi: 10.3791/52480.


CLEC-2 expression is maintained on activated platelets and on platelet microparticles.

Gitz E, Pollitt AY, Gitz-Francois JJ, Alshehri O, Mori J, Montague S, Nash GB, Douglas MR, Gardiner EE, Andrews RK, Buckley CD, Harrison P, Watson SP.

Blood. 2014 Oct 2;124(14):2262-70. doi: 10.1182/blood-2014-05-572818. Epub 2014 Aug 22.


Editorial: dedicated to the memory of Professor Oguz Baskurt.

Nash GB, Gori T.

Biorheology. 2014;51(2-3):81. doi: 10.3233/BIR-140666. No abstract available.


The cellular and molecular rheology of malaria.

Cooke BM, Stuart J, Nash GB.

Biorheology. 2014;51(2-3):99-119. doi: 10.3233/BIR-140654. Review.


Electroporation and microinjection successfully deliver single-stranded and duplex DNA into live cells as detected by FRET measurements.

Bamford RA, Zhao ZY, Hotchin NA, Styles IB, Nash GB, Tucker JH, Bicknell R.

PLoS One. 2014 Apr 22;9(4):e95097. doi: 10.1371/journal.pone.0095097. eCollection 2014.


Fåhraeus Medal Award Lecture 2013. Cellular hemorheology: the importance of getting small cells through small gaps.

Nash GB.

Biorheology. 2013;50(5-6):223-39. doi: 10.3233/BIR-130646. No abstract available.


Silica nanoparticles for micro-particle imaging velocimetry: fluorosurfactant improves nanoparticle stability and brightness of immobilized iridium(III) complexes.

Lewis DJ, Dore V, Rogers NJ, Mole TK, Nash GB, Angeli P, Pikramenou Z.

Langmuir. 2013 Nov 26;29(47):14701-8. doi: 10.1021/la403172m. Epub 2013 Nov 13.


Analysis of the effects of stromal cells on the migration of lymphocytes into and through inflamed tissue using 3-D culture models.

Jeffery HC, Buckley CD, Moss P, Rainger GE, Nash GB, McGettrick HM.

J Immunol Methods. 2013 Dec 31;400-401:45-57. doi: 10.1016/j.jim.2013.10.004. Epub 2013 Oct 16.


Adhesion of tumor cells to matrices and endothelium.

Yates CM, McGettrick HM, Nash GB, Rainger GE.

Methods Mol Biol. 2014;1070:57-75. doi: 10.1007/978-1-4614-8244-4_5.


Crosstalk between mesenchymal stem cells and endothelial cells leads to downregulation of cytokine-induced leukocyte recruitment.

Luu NT, McGettrick HM, Buckley CD, Newsome PN, Rainger GE, Frampton J, Nash GB.

Stem Cells. 2013 Dec;31(12):2690-702. doi: 10.1002/stem.1511.


Infection and transmission dynamics of rKSHV.219 in primary endothelial cells.

Jeffery HC, Wheat RL, Blackbourn DJ, Nash GB, Butler LM.

J Virol Methods. 2013 Oct;193(1):251-9. doi: 10.1016/j.jviromet.2013.06.001. Epub 2013 Jun 10.


Comparative rheology of the adhesion of platelets and leukocytes from flowing blood: why are platelets so small?

Watts T, Barigou M, Nash GB.

Am J Physiol Heart Circ Physiol. 2013 Jun 1;304(11):H1483-94. doi: 10.1152/ajpheart.00881.2012. Epub 2013 Apr 12.


The physiological and pathophysiological roles of platelet CLEC-2.

Navarro-Núñez L, Langan SA, Nash GB, Watson SP.

Thromb Haemost. 2013 Jun;109(6):991-8. doi: 10.1160/TH13-01-0060. Epub 2013 Mar 28. Review.


The role of platelet-endothelial cell adhesion molecule-1 in atheroma formation varies depending on the site-specific hemodynamic environment.

Harrison M, Smith E, Ross E, Krams R, Segers D, Buckley CD, Nash GB, Rainger GE.

Arterioscler Thromb Vasc Biol. 2013 Apr;33(4):694-701. doi: 10.1161/ATVBAHA.112.300379. Epub 2013 Jan 31.


Integrin-substrate interactions underlying shear-induced inhibition of the inflammatory response of endothelial cells.

Luu NT, Glen KE, Egginton S, Rainger GE, Nash GB.

Thromb Haemost. 2013 Feb;109(2):298-308. doi: 10.1160/TH12-06-0400. Epub 2012 Dec 13.


Kaposi's sarcoma-associated herpesvirus inhibits expression and function of endothelial cell major histocompatibility complex class II via suppressor of cytokine signaling 3.

Butler LM, Jeffery HC, Wheat RL, Long HM, Rae PC, Nash GB, Blackbourn DJ.

J Virol. 2012 Jul;86(13):7158-66. doi: 10.1128/JVI.06908-11. Epub 2012 Apr 24.


Tissue stroma as a regulator of leukocyte recruitment in inflammation.

McGettrick HM, Butler LM, Buckley CD, Rainger GE, Nash GB.

J Leukoc Biol. 2012 Mar;91(3):385-400. doi: 10.1189/jlb.0911458. Epub 2012 Jan 6. Review.


CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development.

Finney BA, Schweighoffer E, Navarro-Núñez L, Bénézech C, Barone F, Hughes CE, Langan SA, Lowe KL, Pollitt AY, Mourao-Sa D, Sheardown S, Nash GB, Smithers N, Reis e Sousa C, Tybulewicz VL, Watson SP.

Blood. 2012 Feb 16;119(7):1747-56. doi: 10.1182/blood-2011-09-380709. Epub 2011 Dec 20.


Modulation of functional responses of endothelial cells linked to angiogenesis and inflammation by shear stress: differential effects of the mechanotransducer CD31.

Glen K, Luu NT, Ross E, Buckley CD, Rainger GE, Egginton S, Nash GB.

J Cell Physiol. 2012 Jun;227(6):2710-21. doi: 10.1002/jcp.23015.


Prostaglandin D2 regulates CD4+ memory T cell trafficking across blood vascular endothelium and primes these cells for clearance across lymphatic endothelium.

Ahmed SR, McGettrick HM, Yates CM, Buckley CD, Ratcliffe MJ, Nash GB, Rainger GE.

J Immunol. 2011 Aug 1;187(3):1432-9. doi: 10.4049/jimmunol.1100299. Epub 2011 Jun 29.


Identification and angiogenic role of the novel tumor endothelial marker CLEC14A.

Mura M, Swain RK, Zhuang X, Vorschmitt H, Reynolds G, Durant S, Beesley JF, Herbert JM, Sheldon H, Andre M, Sanderson S, Glen K, Luu NT, McGettrick HM, Antczak P, Falciani F, Nash GB, Nagy ZS, Bicknell R.

Oncogene. 2012 Jan 19;31(3):293-305. doi: 10.1038/onc.2011.233. Epub 2011 Jun 27.


The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo.

Woodfin A, Voisin MB, Beyrau M, Colom B, Caille D, Diapouli FM, Nash GB, Chavakis T, Albelda SM, Rainger GE, Meda P, Imhof BA, Nourshargh S.

Nat Immunol. 2011 Jun 26;12(8):761-9. doi: 10.1038/ni.2062.


Endovascular aneurysm repair reverses the increased titer and the inflammatory activity of interleukin-1α in the serum of patients with abdominal aortic aneurysm.

Yates CM, Abdelhamid M, Adam DJ, Nash GB, Bradbury AW, Rainger GE.

J Vasc Surg. 2011 Aug;54(2):497-503. doi: 10.1016/j.jvs.2011.02.061. Epub 2011 May 28.


Docosahexaenoic acid inhibits the adhesion of flowing neutrophils to cytokine stimulated human umbilical vein endothelial cells.

Yates CM, Tull SP, Madden J, Calder PC, Grimble RF, Nash GB, Rainger GE.

J Nutr. 2011 Jul;141(7):1331-4. doi: 10.3945/jn.111.139287. Epub 2011 May 25.


Kaposi's sarcoma-associated herpesvirus infection of endothelial cells inhibits neutrophil recruitment through an interleukin-6-dependent mechanism: a new paradigm for viral immune evasion.

Butler LM, Jeffery HC, Wheat RL, Rae PC, Townsend K, Alkharsah KR, Schulz TF, Nash GB, Blackbourn DJ.

J Virol. 2011 Jul;85(14):7321-32. doi: 10.1128/JVI.00021-11. Epub 2011 May 4.


Endothelial cell-borne platelet bridges selectively recruit monocytes in human and mouse models of vascular inflammation.

Kuckleburg CJ, Yates CM, Kalia N, Zhao Y, Nash GB, Watson SP, Rainger GE.

Cardiovasc Res. 2011 Jul 1;91(1):134-41. doi: 10.1093/cvr/cvr040. Epub 2011 Feb 1.


Delay of migrating leukocytes by the basement membrane deposited by endothelial cells in long-term culture.

Burton VJ, Butler LM, McGettrick HM, Stone PC, Jeffery HC, Savage CO, Rainger GE, Nash GB.

Exp Cell Res. 2011 Feb 1;317(3):276-92. doi: 10.1016/j.yexcr.2010.10.022. Epub 2010 Nov 4.


Identification of a lysosomal pathway regulating degradation of the bone morphogenetic protein receptor type II.

Durrington HJ, Upton PD, Hoer S, Boname J, Dunmore BJ, Yang J, Crilley TK, Butler LM, Blackbourn DJ, Nash GB, Lehner PJ, Morrell NW.

J Biol Chem. 2010 Nov 26;285(48):37641-9. doi: 10.1074/jbc.M110.132415. Epub 2010 Sep 24.

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