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Items: 1 to 50 of 63

1.

Permeability analyses and three dimensional imaging of interferon gamma-induced barrier disintegration in intestinal organoids.

Bardenbacher M, Ruder B, Britzen-Laurent N, Schmid B, Waldner M, Naschberger E, Scharl M, Müller W, Günther C, Becker C, Stürzl M, Tripal P.

Stem Cell Res. 2019 Mar;35:101383. doi: 10.1016/j.scr.2019.101383. Epub 2019 Feb 7.

2.

PU.1 controls fibroblast polarization and tissue fibrosis.

Wohlfahrt T, Rauber S, Uebe S, Luber M, Soare A, Ekici A, Weber S, Matei AE, Chen CW, Maier C, Karouzakis E, Kiener HP, Pachera E, Dees C, Beyer C, Daniel C, Gelse K, Kremer AE, Naschberger E, Stürzl M, Butter F, Sticherling M, Finotto S, Kreuter A, Kaplan MH, Jüngel A, Gay S, Nutt SL, Boykin DW, Poon GMK, Distler O, Schett G, Distler JHW, Ramming A.

Nature. 2019 Feb;566(7744):344-349. doi: 10.1038/s41586-019-0896-x. Epub 2019 Jan 30.

PMID:
30700907
3.

β6 -integrin serves as a novel serum tumor marker for colorectal carcinoma.

Bengs S, Becker E, Busenhart P, Spalinger MR, Raselli T, Kasper S, Lang S, Atrott K, Mamie C, Vavricka SR, von Boehmer L, Knuth A, Tuomisto A, Mäkinen MJ, Hruz P, Turina M, Rickenbacher A, Petrowsky H, Weber A, Frei P, Halama M, Jenkins G, Sheppard D, Croner RS, Christoph J, Britzen-Laurent N, Naschberger E, Schellerer V, Stürzl M, Fried M, Rogler G, Scharl M.

Int J Cancer. 2019 Aug 1;145(3):678-685. doi: 10.1002/ijc.32137. Epub 2019 Jan 29.

PMID:
30653264
4.

Soluble intercellular adhesion molecule-1 is a prognostic marker in colorectal carcinoma.

Schellerer VS, Langheinrich MC, Zver V, Grützmann R, Stürzl M, Gefeller O, Naschberger E, Merkel S.

Int J Colorectal Dis. 2019 Feb;34(2):309-317. doi: 10.1007/s00384-018-3198-0. Epub 2018 Nov 23.

5.

IFN-γ-response mediator GBP-1 represses human cell proliferation by inhibiting the Hippo signaling transcription factor TEAD.

Unterer B, Wiesmann V, Gunasekaran M, Sticht H, Tenkerian C, Behrens J, Leone M, Engel FB, Britzen-Laurent N, Naschberger E, Wittenberg T, Stürzl M.

Biochem J. 2018 Sep 25;475(18):2955-2967. doi: 10.1042/BCJ20180123.

6.

A model of chronic enthesitis and new bone formation characterized by multimodal imaging.

Czegley C, Gillmann C, Schauer C, Seyler L, Reinwald C, Hahn M, Uder M, Jochmann K, Naschberger E, Stock M, Schett G, Bäuerle T, Hoffmann MH.

Dis Model Mech. 2018 Aug 30;11(9). pii: dmm034041. doi: 10.1242/dmm.034041.

7.

Isolation of Human Endothelial Cells from Normal Colon and Colorectal Carcinoma - An Improved Protocol.

Naschberger E, Regensburger D, Tenkerian C, Langheinrich M, Engel FB, Geppert C, Hartmann A, Grützmann R, Schellerer VS, Stürzl M.

J Vis Exp. 2018 Apr 4;(134). doi: 10.3791/57400.

PMID:
29683458
8.

Usability and Suitability of the Omics-Integrating Analysis Platform tranSMART for Translational Research and Education.

Christoph J, Knell C, Bosserhoff A, Naschberger E, Stürzl M, Rübner M, Seuss H, Ruh M, Prokosch HU, Sedlmayr B.

Appl Clin Inform. 2017 Oct;8(4):1173-1183. doi: 10.4338/ACI-2017-05-RA-0085. Epub 2017 Dec 21.

9.

Two Years of tranSMART in a University Hospital for Translational Research and Education.

Christoph J, Knell C, Naschberger E, Stürzl M, Maier C, Prokosch HU, Sedlmayr M.

Stud Health Technol Inform. 2017;236:70-79.

PMID:
28508781
10.

Efficacy of aflibercept (EYLEA®) on inhibition of human VEGF in vitro.

Schicht M, Hesse K, Schröder H, Naschberger E, Lamprecht W, Garreis F, Paulsen FP, Bräuer L.

Ann Anat. 2017 May;211:135-139. doi: 10.1016/j.aanat.2017.02.005. Epub 2017 Mar 7.

PMID:
28279730
11.

Processing and secretion of guanylate binding protein-1 depend on inflammatory caspase activity.

Naschberger E, Geißdörfer W, Bogdan C, Tripal P, Kremmer E, Stürzl M, Britzen-Laurent N.

J Cell Mol Med. 2017 Sep;21(9):1954-1966. doi: 10.1111/jcmm.13116. Epub 2017 Mar 8.

12.

Matricellular protein SPARCL1 regulates tumor microenvironment-dependent endothelial cell heterogeneity in colorectal carcinoma.

Naschberger E, Liebl A, Schellerer VS, Schütz M, Britzen-Laurent N, Kölbel P, Schaal U, Haep L, Regensburger D, Wittmann T, Klein-Hitpass L, Rau TT, Dietel B, Méniel VS, Clarke AR, Merkel S, Croner RS, Hohenberger W, Stürzl M.

J Clin Invest. 2016 Nov 1;126(11):4187-4204. doi: 10.1172/JCI78260. Epub 2016 Oct 10.

13.

Pathophysiological role of guanylate-binding proteins in gastrointestinal diseases.

Britzen-Laurent N, Herrmann C, Naschberger E, Croner RS, Stürzl M.

World J Gastroenterol. 2016 Jul 28;22(28):6434-43. doi: 10.3748/wjg.v22.i28.6434. Review.

14.

IRAK-M Expression in Tumor Cells Supports Colorectal Cancer Progression through Reduction of Antimicrobial Defense and Stabilization of STAT3.

Kesselring R, Glaesner J, Hiergeist A, Naschberger E, Neumann H, Brunner SM, Wege AK, Seebauer C, Köhl G, Merkl S, Croner RS, Hackl C, Stürzl M, Neurath MF, Gessner A, Schlitt HJ, Geissler EK, Fichtner-Feigl S.

Cancer Cell. 2016 May 9;29(5):684-696. doi: 10.1016/j.ccell.2016.03.014. Epub 2016 Apr 14.

15.

Identification of Predictive Markers for Response to Neoadjuvant Chemoradiation in Rectal Carcinomas by Proteomic Isotope Coded Protein Label (ICPL) Analysis.

Croner RS, Sevim M, Metodiev MV, Jo P, Ghadimi M, Schellerer V, Brunner M, Geppert C, Rau T, Stürzl M, Naschberger E, Matzel KE, Hohenberger W, Lottspeich F, Kellermann J.

Int J Mol Sci. 2016 Feb 4;17(2):209. doi: 10.3390/ijms17020209.

16.

Interferon Gamma Counteracts the Angiogenic Switch and Induces Vascular Permeability in Dextran Sulfate Sodium Colitis in Mice.

Haep L, Britzen-Laurent N, Weber TG, Naschberger E, Schaefer A, Kremmer E, Foersch S, Vieth M, Scheuer W, Wirtz S, Waldner M, Stürzl M.

Inflamm Bowel Dis. 2015 Oct;21(10):2360-71. doi: 10.1097/MIB.0000000000000490.

PMID:
26164664
17.

Absolute quantification of DcR3 and GDF15 from human serum by LC-ESI MS.

Lancrajan I, Schneider-Stock R, Naschberger E, Schellerer VS, Stürzl M, Enz R.

J Cell Mol Med. 2015 Jul;19(7):1656-71. doi: 10.1111/jcmm.12540. Epub 2015 Mar 30.

18.

Aggregated neutrophil extracellular traps limit inflammation by degrading cytokines and chemokines.

Schauer C, Janko C, Munoz LE, Zhao Y, Kienhöfer D, Frey B, Lell M, Manger B, Rech J, Naschberger E, Holmdahl R, Krenn V, Harrer T, Jeremic I, Bilyy R, Schett G, Hoffmann M, Herrmann M.

Nat Med. 2014 May;20(5):511-7. doi: 10.1038/nm.3547. Epub 2014 Apr 28.

PMID:
24784231
19.

Quantitative proteome profiling of lymph node-positive vs. -negative colorectal carcinomas pinpoints MX1 as a marker for lymph node metastasis.

Croner RS, Stürzl M, Rau TT, Metodieva G, Geppert CI, Naschberger E, Lausen B, Metodiev MV.

Int J Cancer. 2014 Dec 15;135(12):2878-86. doi: 10.1002/ijc.28929. Epub 2014 May 12.

20.

Structural proteins of Kaposi's sarcoma-associated herpesvirus antagonize p53-mediated apoptosis.

Chudasama P, Konrad A, Jochmann R, Lausen B, Holz P, Naschberger E, Neipel F, Britzen-Laurent N, Stürzl M.

Oncogene. 2015 Jan 29;34(5):639-49. doi: 10.1038/onc.2013.595. Epub 2014 Jan 27.

PMID:
24469037
21.

Guanylate binding protein 1-mediated interaction of T cell antigen receptor signaling with the cytoskeleton.

Forster F, Paster W, Supper V, Schatzlmaier P, Sunzenauer S, Ostler N, Saliba A, Eckerstorfer P, Britzen-Laurent N, Schütz G, Schmid JA, Zlabinger GJ, Naschberger E, Stürzl M, Stockinger H.

J Immunol. 2014 Jan 15;192(2):771-81. doi: 10.4049/jimmunol.1300377. Epub 2013 Dec 13.

22.

Tumor-associated fibroblasts isolated from colorectal cancer tissues exhibit increased ICAM-1 expression and affinity for monocytes.

Schellerer VS, Langheinrich M, Hohenberger W, Croner RS, Merkel S, Rau TT, Stürzl M, Naschberger E.

Oncol Rep. 2014 Jan;31(1):255-61. doi: 10.3892/or.2013.2860. Epub 2013 Nov 20.

PMID:
24253852
23.

Gamma interferon-induced guanylate binding protein 1 is a novel actin cytoskeleton remodeling factor.

Ostler N, Britzen-Laurent N, Liebl A, Naschberger E, Lochnit G, Ostler M, Forster F, Kunzelmann P, Ince S, Supper V, Praefcke GJ, Schubert DW, Stockinger H, Herrmann C, Stürzl M.

Mol Cell Biol. 2014 Jan;34(2):196-209. doi: 10.1128/MCB.00664-13. Epub 2013 Nov 4.

24.

IFN-γ-driven intratumoral microenvironment exhibits superior prognostic effect compared with an IFN-α-driven microenvironment in patients with colon carcinoma.

Grenz S, Naschberger E, Merkel S, Britzen-Laurent N, Schaal U, Konrad A, Aigner M, Rau TT, Hartmann A, Croner RS, Hohenberger W, Stürzl M.

Am J Pathol. 2013 Dec;183(6):1897-1909. doi: 10.1016/j.ajpath.2013.08.025. Epub 2013 Oct 8.

PMID:
24121019
25.

Expression and localization of axin 2 in colorectal carcinoma and its clinical implication.

Schaal U, Grenz S, Merkel S, Rau TT, Hadjihannas MV, Kremmer E, Chudasama P, Croner RS, Behrens J, Stürzl M, Naschberger E.

Int J Colorectal Dis. 2013 Nov;28(11):1469-78. doi: 10.1007/s00384-013-1709-6. Epub 2013 May 24.

PMID:
23702820
26.

Multiple interferon regulatory factor and NF-κB sites cooperate in mediating cell-type- and maturation-specific activation of the human CD83 promoter in dendritic cells.

Stein MF, Lang S, Winkler TH, Deinzer A, Erber S, Nettelbeck DM, Naschberger E, Jochmann R, Stürzl M, Slany RK, Werner T, Steinkasserer A, Knippertz I.

Mol Cell Biol. 2013 Apr;33(7):1331-44. doi: 10.1128/MCB.01051-12. Epub 2013 Jan 22.

27.

Guanylate-binding protein 1 expression from embryonal endothelial progenitor cells reduces blood vessel density and cellular apoptosis in an axially vascularised tissue-engineered construct.

Bleiziffer O, Hammon M, Arkudas A, Taeger CD, Beier JP, Amann K, Naschberger E, Stürzl M, Horch RE, Kneser U.

BMC Biotechnol. 2012 Dec 6;12:94. doi: 10.1186/1472-6750-12-94.

28.

GBP-1 acts as a tumor suppressor in colorectal cancer cells.

Britzen-Laurent N, Lipnik K, Ocker M, Naschberger E, Schellerer VS, Croner RS, Vieth M, Waldner M, Steinberg P, Hohenadl C, Stürzl M.

Carcinogenesis. 2013 Jan;34(1):153-62. doi: 10.1093/carcin/bgs310. Epub 2012 Oct 6.

PMID:
23042300
29.

Molecular mechanisms of lymphatic metastasis in solid tumors of the gastrointestinal tract.

Langheinrich MC, Schellerer V, Perrakis A, Lohmüller C, Schildberg C, Naschberger E, Stürzl M, Hohenberger W, Croner RS.

Int J Clin Exp Pathol. 2012;5(7):614-23. Epub 2012 Sep 5. Review.

30.

Molecular characterization of peripheral arterial disease in proximal extremity arteries.

Croner RS, Balzer K, Schellerer V, Müller V, Schlabrakowsi A, Stürzl M, Naschberger E, Lang W.

J Surg Res. 2012 Dec;178(2):1046-58. doi: 10.1016/j.jss.2012.07.024. Epub 2012 Aug 3.

PMID:
22884453
31.

IFN-γ and TNF-α-induced GBP-1 inhibits epithelial cell proliferation through suppression of β-catenin/TCF signaling.

Capaldo CT, Beeman N, Hilgarth RS, Nava P, Louis NA, Naschberger E, Stürzl M, Parkos CA, Nusrat A.

Mucosal Immunol. 2012 Nov;5(6):681-90. doi: 10.1038/mi.2012.41. Epub 2012 Jun 13.

32.

The ephrin receptor tyrosine kinase A2 is a cellular receptor for Kaposi's sarcoma–associated herpesvirus.

Hahn AS, Kaufmann JK, Wies E, Naschberger E, Panteleev-Ivlev J, Schmidt K, Holzer A, Schmidt M, Chen J, König S, Ensser A, Myoung J, Brockmeyer NH, Stürzl M, Fleckenstein B, Neipel F.

Nat Med. 2012 Jun;18(6):961-6. doi: 10.1038/nm.2805.

33.

Tetramerization of human guanylate-binding protein 1 is mediated by coiled-coil formation of the C-terminal α-helices.

Syguda A, Bauer M, Benscheid U, Ostler N, Naschberger E, Ince S, Stürzl M, Herrmann C.

FEBS J. 2012 Jul;279(14):2544-54. doi: 10.1111/j.1742-4658.2012.08637.x. Epub 2012 Jun 15.

34.

A novel chip-based parallel transfection assay to evaluate paracrine cell interactions.

Kuhn E, Naschberger E, Konrad A, Croner RS, Britzen-Laurent N, Jochmann R, Münstedt H, Stürzl M.

Lab Chip. 2012 Apr 7;12(7):1363-72. doi: 10.1039/c2lc20724a. Epub 2012 Feb 22.

PMID:
22354004
35.

The clinical value of von Willebrand factor in colorectal carcinomas.

Schellerer VS, Mueller-Bergh L, Merkel S, Zimmermann R, Weiss D, Schlabrakowski A, Naschberger E, Stürzl M, Hohenberger W, Croner RS.

Am J Transl Res. 2011;3(5):445-53. Epub 2011 Sep 23.

36.

Notch3 signalling promotes tumour growth in colorectal cancer.

Serafin V, Persano L, Moserle L, Esposito G, Ghisi M, Curtarello M, Bonanno L, Masiero M, Ribatti D, Stürzl M, Naschberger E, Croner RS, Jubb AM, Harris AL, Koeppen H, Amadori A, Indraccolo S.

J Pathol. 2011 Aug;224(4):448-60. doi: 10.1002/path.2895. Epub 2011 May 19.

PMID:
21598247
37.

Isolation of endothelial cells from human tumors.

Naschberger E, Schellerer VS, Rau TT, Croner RS, Stürzl M.

Methods Mol Biol. 2011;731:209-18. doi: 10.1007/978-1-61779-080-5_18.

PMID:
21516410
38.

Endothelial progenitor cells are integrated in newly formed capillaries and alter adjacent fibrovascular tissue after subcutaneous implantation in a fibrin matrix.

Bleiziffer O, Hammon M, Naschberger E, Lipnik K, Arkudas A, Rath S, Pryymachuk G, Beier JP, Stürzl M, Horch RE, Kneser U.

J Cell Mol Med. 2011 Nov;15(11):2452-61. doi: 10.1111/j.1582-4934.2010.01247.x.

39.

Intracellular trafficking of guanylate-binding proteins is regulated by heterodimerization in a hierarchical manner.

Britzen-Laurent N, Bauer M, Berton V, Fischer N, Syguda A, Reipschläger S, Naschberger E, Herrmann C, Stürzl M.

PLoS One. 2010 Dec 7;5(12):e14246. doi: 10.1371/journal.pone.0014246.

40.

Increased expression of guanylate binding protein-1 in lesional skin of patients with cutaneous lupus erythematosus.

Naschberger E, Wenzel J, Kretz CC, Herrmann M, Stürzl M, Kuhn A.

Exp Dermatol. 2011 Feb;20(2):102-6. doi: 10.1111/j.1600-0625.2010.01160.x. Epub 2010 Dec 2.

PMID:
21121962
41.

Reverse transfected cell microarrays in infectious disease research.

Konrad A, Jochmann R, Kuhn E, Naschberger E, Chudasama P, Stürzl M.

Methods Mol Biol. 2011;706:107-18. doi: 10.1007/978-1-61737-970-3_9.

PMID:
21104058
42.

One step nucleic acid amplification (OSNA) - a new method for lymph node staging in colorectal carcinomas.

Croner RS, Schellerer V, Demund H, Schildberg C, Papadopulos T, Naschberger E, Stürzl M, Matzel KE, Hohenberger W, Schlabrakowski A.

J Transl Med. 2010 Sep 6;8:83. doi: 10.1186/1479-5876-8-83.

43.

Role of guanylate binding protein-1 in vascular defects associated with chronic inflammatory diseases.

Hammon M, Herrmann M, Bleiziffer O, Pryymachuk G, Andreoli L, Munoz LE, Amann KU, Mondini M, Gariglio M, Airó P, Schellerer VS, Hatzopoulos AK, Horch RE, Kneser U, Stürzl M, Naschberger E.

J Cell Mol Med. 2011 Jul;15(7):1582-92. doi: 10.1111/j.1582-4934.2010.01146.x.

44.

Interferon gamma-induced human guanylate binding protein 1 inhibits mammary tumor growth in mice.

Lipnik K, Naschberger E, Gonin-Laurent N, Kodajova P, Petznek H, Rungaldier S, Astigiano S, Ferrini S, Stürzl M, Hohenadl C.

Mol Med. 2010 May-Jun;16(5-6):177-87. doi: 10.2119/molmed.2009.00172. Epub 2010 Feb 5.

45.

T17b murine embryonal endothelial progenitor cells can be induced towards both proliferation and differentiation in a fibrin matrix.

Bleiziffer O, Horch RE, Hammon M, Arkudas A, Naschberger E, Rath S, Pryymachuk G, Beier JP, Hatzopoulos AK, Stürzl M, Kneser U.

J Cell Mol Med. 2009 May;13(5):926-35. doi: 10.1111/j.1582-4934.2008.00527.x.

46.

Malignant progression of invasive tumour cells seen in hypoxia present an accumulation of beta-catenin in the nucleus at the tumour front.

Demir R, Dimmler A, Naschberger E, Demir I, Papadopoulos T, Melling N, Sturzl M, Hohenberger W.

Exp Mol Pathol. 2009 Oct;87(2):109-16. doi: 10.1016/j.yexmp.2009.05.004. Epub 2009 May 28.

PMID:
19481539
47.

Interferon-alpha counteracts the angiogenic switch and reduces tumor cell proliferation in a spontaneous model of prostatic cancer.

Persano L, Moserle L, Esposito G, Bronte V, Barbieri V, Iafrate M, Gardiman MP, Larghero P, Pfeffer U, Naschberger E, Stürzl M, Indraccolo S, Amadori A.

Carcinogenesis. 2009 May;30(5):851-60. doi: 10.1093/carcin/bgp052. Epub 2009 Feb 23.

PMID:
19237608
48.

O-linked N-acetylglucosaminylation of Sp1 inhibits the human immunodeficiency virus type 1 promoter.

Jochmann R, Thurau M, Jung S, Hofmann C, Naschberger E, Kremmer E, Harrer T, Miller M, Schaft N, Stürzl M.

J Virol. 2009 Apr;83(8):3704-18. doi: 10.1128/JVI.01384-08. Epub 2009 Feb 4.

49.

A systems biology approach to identify the combination effects of human herpesvirus 8 genes on NF-kappaB activation.

Konrad A, Wies E, Thurau M, Marquardt G, Naschberger E, Hentschel S, Jochmann R, Schulz TF, Erfle H, Brors B, Lausen B, Neipel F, Stürzl M.

J Virol. 2009 Mar;83(6):2563-74. doi: 10.1128/JVI.01512-08. Epub 2009 Jan 7.

50.

Viral inhibitor of apoptosis vFLIP/K13 protects endothelial cells against superoxide-induced cell death.

Thurau M, Marquardt G, Gonin-Laurent N, Weinländer K, Naschberger E, Jochmann R, Alkharsah KR, Schulz TF, Thome M, Neipel F, Stürzl M.

J Virol. 2009 Jan;83(2):598-611. doi: 10.1128/JVI.00629-08. Epub 2008 Nov 5.

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