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Items: 8


A Quantitative Chemical Proteomic Strategy for Profiling Phosphoprotein Phosphatases from Yeast to Humans.

Lyons SP, Jenkins NP, Nasa I, Choy MS, Adamo ME, Page R, Peti W, Moorhead GB, Kettenbach AN.

Mol Cell Proteomics. 2018 Dec;17(12):2448-2461. doi: 10.1074/mcp.RA118.000822. Epub 2018 Sep 18.


Aurora B opposes PP1 function in mitosis by phosphorylating the conserved PP1-binding RVxF motif in PP1 regulatory proteins.

Nasa I, Rusin SF, Kettenbach AN, Moorhead GB.

Sci Signal. 2018 May 15;11(530). pii: eaai8669. doi: 10.1126/scisignal.aai8669.


Global assessment of its network dynamics reveals that the kinase Plk1 inhibits the phosphatase PP6 to promote Aurora A activity.

Kettenbach AN, Schlosser KA, Lyons SP, Nasa I, Gui J, Adamo ME, Gerber SA.

Sci Signal. 2018 May 15;11(530). pii: eaaq1441. doi: 10.1126/scisignal.aaq1441.


Coordination of Protein Kinase and Phosphoprotein Phosphatase Activities in Mitosis.

Nasa I, Kettenbach AN.

Front Cell Dev Biol. 2018 Mar 22;6:30. doi: 10.3389/fcell.2018.00030. eCollection 2018. Review.


Recruitment of PP1 to the centrosomal scaffold protein CEP192.

Nasa I, Trinkle-Mulcahy L, Douglas P, Chaudhuri S, Lees-Miller SP, Lee KS, Moorhead GB.

Biochem Biophys Res Commun. 2017 Mar 18;484(4):864-870. doi: 10.1016/j.bbrc.2017.02.004. Epub 2017 Feb 8.


The human mitotic kinesin KIF18A binds protein phosphatase 1 (PP1) through a highly conserved docking motif.

De Wever V, Nasa I, Chamousset D, Lloyd D, Nimick M, Xu H, Trinkle-Mulcahy L, Moorhead GB.

Biochem Biophys Res Commun. 2014 Oct 24;453(3):432-7. doi: 10.1016/j.bbrc.2014.09.105. Epub 2014 Oct 1.


Quantitative fragmentome mapping reveals novel, domain-specific partners for the modular protein RepoMan (recruits PP1 onto mitotic chromatin at anaphase).

Prévost M, Chamousset D, Nasa I, Freele E, Morrice N, Moorhead G, Trinkle-Mulcahy L.

Mol Cell Proteomics. 2013 May;12(5):1468-86. doi: 10.1074/mcp.M112.023291. Epub 2013 Jan 29.


Isolation of human mitotic protein phosphatase complexes: identification of a complex between protein phosphatase 1 and the RNA helicase Ddx21.

De Wever V, Lloyd DC, Nasa I, Nimick M, Trinkle-Mulcahy L, Gourlay R, Morrice N, Moorhead GB.

PLoS One. 2012;7(6):e39510. doi: 10.1371/journal.pone.0039510. Epub 2012 Jun 28.

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