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Items: 1 to 50 of 59

1.

Characterization of a novel CRAC inhibitor that potently blocks human T cell activation and effector functions.

Chen G, Panicker S, Lau KY, Apparsundaram S, Patel VA, Chen SL, Soto R, Jung JK, Ravindran P, Okuhara D, Bohnert G, Che Q, Rao PE, Allard JD, Badi L, Bitter HM, Nunn PA, Narula SK, DeMartino JA.

Mol Immunol. 2013 Jul;54(3-4):355-67. doi: 10.1016/j.molimm.2012.12.011. Epub 2013 Jan 26.

PMID:
23357789
2.

College student smokers: former versus current and nonsmokers.

Berg CJ, Schauer GL, Rodgers K, Narula SK.

Am J Prev Med. 2012 Nov;43(5 Suppl 3):S229-36. doi: 10.1016/j.amepre.2012.07.038.

PMID:
23079221
3.

Characterization of peripheral human cannabinoid receptor (hCB2) expression and pharmacology using a novel radioligand, [35S]Sch225336.

Gonsiorek W, Hesk D, Chen SC, Kinsley D, Fine JS, Jackson JV, Bober LA, Deno G, Bian H, Fossetta J, Lunn CA, Kozlowski JA, Lavey B, Piwinski J, Narula SK, Lundell DJ, Hipkin RW.

J Biol Chem. 2006 Sep 22;281(38):28143-51. Epub 2006 Jun 5.

4.

A novel cannabinoid peripheral cannabinoid receptor-selective inverse agonist blocks leukocyte recruitment in vivo.

Lunn CA, Fine JS, Rojas-Triana A, Jackson JV, Fan X, Kung TT, Gonsiorek W, Schwarz MA, Lavey B, Kozlowski JA, Narula SK, Lundell DJ, Hipkin RW, Bober LA.

J Pharmacol Exp Ther. 2006 Feb;316(2):780-8. Epub 2005 Oct 28.

PMID:
16258021
5.

Women making strides in big pharma.

Strader CD, Narula SK, Lachowicz JE.

Science. 2005 Sep 9;309(5741):1673. No abstract available.

PMID:
16150991
6.

The pyrimidinergic P2Y6 receptor mediates a novel release of proinflammatory cytokines and chemokines in monocytic cells stimulated with UDP.

Cox MA, Gomes B, Palmer K, Du K, Wiekowski M, Wilburn B, Petro M, Chou CC, Desquitado C, Schwarz M, Lunn C, Lundell D, Narula SK, Zavodny PJ, Jenh CH.

Biochem Biophys Res Commun. 2005 May 6;330(2):467-73.

PMID:
15796906
7.

Blocking ion channel KCNN4 alleviates the symptoms of experimental autoimmune encephalomyelitis in mice.

Reich EP, Cui L, Yang L, Pugliese-Sivo C, Golovko A, Petro M, Vassileva G, Chu I, Nomeir AA, Zhang LK, Liang X, Kozlowski JA, Narula SK, Zavodny PJ, Chou CC.

Eur J Immunol. 2005 Apr;35(4):1027-36.

8.

Inhibition of the development of collagen-induced arthritis in rhesus monkeys by a small molecular weight antagonist of CCR5.

Vierboom MP, Zavodny PJ, Chou CC, Tagat JR, Pugliese-Sivo C, Strizki J, Steensma RW, McCombie SW, Celebi-Paul L, Remarque E, Jonker M, Narula SK, Hart B.

Arthritis Rheum. 2005 Feb;52(2):627-36.

9.

Interleukin-17 promotes angiogenesis and tumor growth.

Numasaki M, Fukushi J, Ono M, Narula SK, Zavodny PJ, Kudo T, Robbins PD, Tahara H, Lotze MT.

Blood. 2003 Apr 1;101(7):2620-7. Epub 2002 Oct 31.

PMID:
12411307
10.

Human B cell-attracting chemokine 1 (BCA-1; CXCL13) is an agonist for the human CXCR3 receptor.

Jenh CH, Cox MA, Hipkin W, Lu T, Pugliese-Sivo C, Gonsiorek W, Chou CC, Narula SK, Zavodny PJ.

Cytokine. 2001 Aug 7;15(3):113-21.

PMID:
11554781
11.
12.

Aberrant in vivo T helper type 2 cell response and impaired eosinophil recruitment in CC chemokine receptor 8 knockout mice.

Chensue SW, Lukacs NW, Yang TY, Shang X, Frait KA, Kunkel SL, Kung T, Wiekowski MT, Hedrick JA, Cook DN, Zingoni A, Narula SK, Zlotnik A, Barrat FJ, O'Garra A, Napolitano M, Lira SA.

J Exp Med. 2001 Mar 5;193(5):573-84.

13.

Regulatory effects of interleukin-4 and interleukin-10 on human neutrophil function ex vivo and on neutrophil influx in a rat model of arthritis.

Bober LA, Rojas-Triana A, Jackson JV, Leach MW, Manfra D, Narula SK, Grace MJ.

Arthritis Rheum. 2000 Dec;43(12):2660-7.

14.

CCR6 mediates dendritic cell localization, lymphocyte homeostasis, and immune responses in mucosal tissue.

Cook DN, Prosser DM, Forster R, Zhang J, Kuklin NA, Abbondanzo SJ, Niu XD, Chen SC, Manfra DJ, Wiekowski MT, Sullivan LM, Smith SR, Greenberg HB, Narula SK, Lipp M, Lira SA.

Immunity. 2000 May;12(5):495-503.

15.

Signaling by covalent heterodimers of interferon-gamma. Evidence for one-sided signaling in the active tetrameric receptor complex.

Krause CD, Lunn CA, Izotova LS, Mirochnitchenko O, Kotenko SV, Lundell DJ, Narula SK, Pestka S.

J Biol Chem. 2000 Jul 28;275(30):22995-3004.

16.

Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma.

Yang TY, Chen SC, Leach MW, Manfra D, Homey B, Wiekowski M, Sullivan L, Jenh CH, Narula SK, Chensue SW, Lira SA.

J Exp Med. 2000 Feb 7;191(3):445-54.

17.
18.

Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity.

Egan RW, Athwal D, Bodmer MW, Carter JM, Chapman RW, Chou CC, Cox MA, Emtage JS, Fernandez X, Genatt N, Indelicato SR, Jenh CH, Kreutner W, Kung TT, Mauser PJ, Minnicozzi M, Murgolo NJ, Narula SK, Petro ME, Schilling A, Sehring S, Stelts D, Stephens S, Taremi SS, Zurcher J, et al.

Arzneimittelforschung. 1999 Sep;49(9):779-90.

PMID:
10514907
19.

Cutting edge: species specificity of the CC chemokine 6Ckine signaling through the CXC chemokine receptor CXCR3: human 6Ckine is not a ligand for the human or mouse CXCR3 receptors.

Jenh CH, Cox MA, Kaminski H, Zhang M, Byrnes H, Fine J, Lundell D, Chou CC, Narula SK, Zavodny PJ.

J Immunol. 1999 Apr 1;162(7):3765-9.

20.

Recipient pretreatment with mammalian IL-10 prolongs mouse cardiac allograft survival by inhibition of anti-donor T cell responses.

Li W, Fu F, Lu L, Narula SK, Fung JJ, Thomson AW, Qian S.

Transplant Proc. 1999 Feb-Mar;31(1-2):115. No abstract available.

PMID:
10083035
21.

Structural characterization of nitric oxide synthase isoforms reveals striking active-site conservation.

Fischmann TO, Hruza A, Niu XD, Fossetta JD, Lunn CA, Dolphin E, Prongay AJ, Reichert P, Lundell DJ, Narula SK, Weber PC.

Nat Struct Biol. 1999 Mar;6(3):233-42.

PMID:
10074942
22.

An inhibitor of CD28-CD80 interactions impairs CD28-mediated costimulation of human CD4 T cells.

Fine JS, Macosko HD, Justice L, Chou CC, Jenh CH, Narula SK, Zavodny PJ.

Cell Immunol. 1999 Jan 10;191(1):49-59.

PMID:
9918686
23.

Systemic administration of anti-interleukin-10 antibody prolongs organ allograft survival in normal and presensitized recipients.

Li W, Fu F, Lu L, Narula SK, Fung JJ, Thomson AW, Qian S.

Transplantation. 1998 Dec 27;66(12):1587-96.

PMID:
9884244
24.

Interleukin-10 dose-dependent regulation of CD4+ and CD8+ T cell-mediated graft-versus-host disease.

Blazar BR, Taylor PA, Panoskaltsis-Mortari A, Narula SK, Smith SR, Roncarolo MG, Vallera DA.

Transplantation. 1998 Nov 15;66(9):1220-9.

PMID:
9825821
25.
26.

Regulation of granulocyte colony-stimulating factor gene expression by interleukin-17.

Cai XY, Gommoll CP Jr, Justice L, Narula SK, Fine JS.

Immunol Lett. 1998 May;62(1):51-8.

PMID:
9672148
27.

Development of a CD28 receptor binding-based screen and identification of a biologically active inhibitor.

Jenh CH, Zhang M, Wiekowski M, Tan JC, Fan XD, Hegde V, Patel M, Bryant R, Narula SK, Zavodny PJ, Chou CC.

Anal Biochem. 1998 Feb 1;256(1):47-55.

PMID:
9466796
28.

Immunomodulation of Crohn's disease by interleukin-10.

Narula SK, Cutler D, Grint P.

Agents Actions Suppl. 1998;49:57-65. Review.

PMID:
9426829
29.

A specific stimulator of granulocyte colony-stimulating factor accelerates recovery from cyclophosphamide-induced neutropenia in the mouse.

Fine JS, Cai XY, Justice L, Gommoll CP Jr, Hamilton LD, Waters TA, Narula SK, Bober LA, Grace MJ.

Blood. 1997 Jul 15;90(2):795-802.

PMID:
9226180
30.

Characterization of interleukin-10 receptor expression on B-cell chronic lymphocytic leukemia cells.

Jurlander J, Lai CF, Tan J, Chou CC, Geisler CH, Schriber J, Blumenson LE, Narula SK, Baumann H, Caligiuri MA.

Blood. 1997 Jun 1;89(11):4146-52.

PMID:
9166857
31.

Purification of ADAM 10 from bovine spleen as a TNFalpha convertase.

Lunn CA, Fan X, Dalie B, Miller K, Zavodny PJ, Narula SK, Lundell D.

FEBS Lett. 1997 Jan 6;400(3):333-5.

32.

Structure and humanization of a rat monoclonal Fab to human interleukin-5.

Cook WJ, Walter LJ, Murgolo NJ, Chou CC, Petro M, Zavodny PJ, Narula SK, Ramanathan L, Trotta PP, Nagabhushan TL.

Protein Eng. 1996 Jul;9(7):623-8.

PMID:
8844835
33.

Systemic administration of cellular IL-10 induces an effective, specific, and long-lived immune response against established tumors in mice.

Berman RM, Suzuki T, Tahara H, Robbins PD, Narula SK, Lotze MT.

J Immunol. 1996 Jul 1;157(1):231-8.

PMID:
8683120
34.

Expression of human inducible nitric oxide synthase in Escherichia coli.

Fossetta JD, Niu XD, Lunn CA, Zavodny PJ, Narula SK, Lundell D.

FEBS Lett. 1996 Jan 29;379(2):135-8.

35.

Interleukin 4 retards dissemination of a human B-cell lymphoma in severe combined immunodeficient mice.

Schwarz MA, Tardelli L, Macosko HD, Sullivan LM, Narula SK, Fine JS.

Cancer Res. 1995 Sep 1;55(17):3692-6.

36.

Crystal structure of a complex between interferon-gamma and its soluble high-affinity receptor.

Walter MR, Windsor WT, Nagabhushan TL, Lundell DJ, Lunn CA, Zauodny PJ, Narula SK.

Nature. 1995 Jul 20;376(6537):230-5.

PMID:
7617032
37.

Characterization of recombinant extracellular domain of human interleukin-10 receptor.

Tan JC, Braun S, Rong H, DiGiacomo R, Dolphin E, Baldwin S, Narula SK, Zavodny PJ, Chou CC.

J Biol Chem. 1995 May 26;270(21):12906-11.

38.

The effects of colony stimulating factors on human monocyte cell function.

Bober LA, Grace MJ, Pugliese-Sivo C, Rojas-Triana A, Sullivan LM, Narula SK.

Int J Immunopharmacol. 1995 May;17(5):385-92.

PMID:
7591362
39.

The effect of GM-CSF and G-CSF on human neutrophil function.

Bober LA, Grace MJ, Pugliese-Sivo C, Rojas-Triana A, Waters T, Sullivan LM, Narula SK.

Immunopharmacology. 1995 Mar;29(2):111-9.

PMID:
7539779
40.

Lymphomagenesis in the SCID-hu mouse involves abundant production of human interleukin-10.

Baiocchi RA, Ross ME, Tan JC, Chou CC, Sullivan L, Haldar S, Monne M, Seiden MV, Narula SK, Sklar J, et al.

Blood. 1995 Feb 15;85(4):1063-74.

PMID:
7849294
41.

IL-4 induces neutrophilic maturation of HL-60 cells and activation of human peripheral blood neutrophils.

Bober LA, Waters TA, Pugliese-Sivo CC, Sullivan LM, Narula SK, Grace MJ.

Clin Exp Immunol. 1995 Jan;99(1):129-36.

42.

Influence of IL-10 on murine CFU-pre-B formation.

Fine JS, Macosko HD, Grace MJ, Narula SK.

Exp Hematol. 1994 Nov;22(12):1188-96.

PMID:
7925782
43.

Structural elements required for receptor recognition of human interferon-gamma.

Lundell DL, Narula SK.

Pharmacol Ther. 1994 Oct;64(1):1-21. Review.

PMID:
7531344
44.

Human IL-10 reduces the number of IL-4-induced IgE B cells in cultures of atopic mononuclear cells.

Bober LA, Grace MJ, Pugliese-Sivo C, Waters TA, Sullivan LM, Narula SK.

Int Arch Allergy Immunol. 1994 Sep;105(1):26-31.

PMID:
8086826
45.

Suppression of the allogeneic response by human IL-10: a critical role for suppression of a synergy between IL-2 and TNF-alpha.

Tadmori W, Zhang M, Beavis AJ, Sullivan LM, Narula SK.

Cytokine. 1994 Sep;6(5):462-71.

PMID:
7827283
46.

Stimulation of cytolytic activity by interleukin-10.

Schwarz MA, Hamilton LD, Tardelli L, Narula SK, Sullivan LM.

J Immunother Emphasis Tumor Immunol. 1994 Aug;16(2):95-104.

PMID:
7804532
47.

Importance of the loop connecting A and B helices of human interferon-gamma in recognition by interferon-gamma receptor.

Lundell D, Lunn CA, Senior MM, Zavodny PJ, Narula SK.

J Biol Chem. 1994 Jun 10;269(23):16159-62.

48.

Interleukin-10 enhances gamma delta T cell development in the murine fetal thymus.

Fine JS, Macosko HD, Grace MJ, Narula SK.

Cell Immunol. 1994 Apr 15;155(1):111-22.

PMID:
8168140
49.

Potential interaction of interleukin-4 with endogenous cytokines in vivo.

Sullivan LM, Bober LA, Grace MJ, Braun S, Macosko HD, Payvandi F, Pugliese-Sivo CC, Narula SK.

Pathobiology. 1994;62(2):59-72.

PMID:
7945914
50.

Characterization of interleukin-10 receptors on human and mouse cells.

Tan JC, Indelicato SR, Narula SK, Zavodny PJ, Chou CC.

J Biol Chem. 1993 Oct 5;268(28):21053-9.

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