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Items: 32


Roles of the PDZ-binding motif of HPV 16 E6 protein in oncogenic transformation of human cervical keratinocytes.

Yoshimatsu Y, Nakahara T, Tanaka K, Inagawa Y, Narisawa-Saito M, Yugawa T, Ohno SI, Fujita M, Nakagama H, Kiyono T.

Cancer Sci. 2017 Jul;108(7):1303-1309. doi: 10.1111/cas.13264. Epub 2017 Jun 5.


Oncogenic Ras/ERK signaling activates CDCP1 to promote tumor invasion and metastasis.

Uekita T, Fujii S, Miyazawa Y, Iwakawa R, Narisawa-Saito M, Nakashima K, Tsuta K, Tsuda H, Kiyono T, Yokota J, Sakai R.

Mol Cancer Res. 2014 Oct;12(10):1449-59. doi: 10.1158/1541-7786.MCR-13-0587. Epub 2014 Jun 17.


A critical role of MYC for transformation of human cells by HPV16 E6E7 and oncogenic HRAS.

Narisawa-Saito M, Inagawa Y, Yoshimatsu Y, Haga K, Tanaka K, Egawa N, Ohno S, Ichikawa H, Yugawa T, Fujita M, Kiyono T.

Carcinogenesis. 2012 Apr;33(4):910-7. doi: 10.1093/carcin/bgs104. Epub 2012 Feb 15.


The E1 protein of human papillomavirus type 16 is dispensable for maintenance replication of the viral genome.

Egawa N, Nakahara T, Ohno S, Narisawa-Saito M, Yugawa T, Fujita M, Yamato K, Natori Y, Kiyono T.

J Virol. 2012 Mar;86(6):3276-83. doi: 10.1128/JVI.06450-11. Epub 2012 Jan 11.


An in vitro multistep carcinogenesis model for both HPV-positive and -negative human oral squamous cell carcinomas.

Zushi Y, Narisawa-Saito M, Noguchi K, Yoshimatsu Y, Yugawa T, Egawa N, Fujita M, Urade M, Kiyono T.

Am J Cancer Res. 2011;1(7):869-81. Epub 2011 Aug 18.


NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer.

Shibata T, Kokubu A, Saito S, Narisawa-Saito M, Sasaki H, Aoyagi K, Yoshimatsu Y, Tachimori Y, Kushima R, Kiyono T, Yamamoto M.

Neoplasia. 2011 Sep;13(9):864-73.


DeltaNp63alpha repression of the Notch1 gene supports the proliferative capacity of normal human keratinocytes and cervical cancer cells.

Yugawa T, Narisawa-Saito M, Yoshimatsu Y, Haga K, Ohno S, Egawa N, Fujita M, Kiyono T.

Cancer Res. 2010 May 15;70(10):4034-44. doi: 10.1158/0008-5472.CAN-09-4063. Epub 2010 May 4. Erratum in: Cancer Res. 2010 Jul 1;70(13):5639.


CDC6 interaction with ATR regulates activation of a replication checkpoint in higher eukaryotic cells.

Yoshida K, Sugimoto N, Iwahori S, Yugawa T, Narisawa-Saito M, Kiyono T, Fujita M.

J Cell Sci. 2010 Jan 15;123(Pt 2):225-35. doi: 10.1242/jcs.058693.


Redundant and differential regulation of multiple licensing factors ensures prevention of re-replication in normal human cells.

Sugimoto N, Yoshida K, Tatsumi Y, Yugawa T, Narisawa-Saito M, Waga S, Kiyono T, Fujita M.

J Cell Sci. 2009 Apr 15;122(Pt 8):1184-91. doi: 10.1242/jcs.041889.


[Mechanisms of high-risk human papillomavirus-induced cervical carcinogenesis].

Narisawa-Saito M, Kiyono T.

Nihon Rinsho. 2009 Jan;67(1):53-61. Review. Japanese.


Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.

Sasaki R, Narisawa-Saito M, Yugawa T, Fujita M, Tashiro H, Katabuchi H, Kiyono T.

Carcinogenesis. 2009 Mar;30(3):423-31. doi: 10.1093/carcin/bgp007. Epub 2009 Jan 6.


Involvement of human ORC and TRF2 in pre-replication complex assembly at telomeres.

Tatsumi Y, Ezura K, Yoshida K, Yugawa T, Narisawa-Saito M, Kiyono T, Ohta S, Obuse C, Fujita M.

Genes Cells. 2008 Oct;13(10):1045-59. doi: 10.1111/j.1365-2443.2008.01224.x. Epub 2008 Aug 29.


An in vitro multistep carcinogenesis model for human cervical cancer.

Narisawa-Saito M, Yoshimatsu Y, Ohno S, Yugawa T, Egawa N, Fujita M, Hirohashi S, Kiyono T.

Cancer Res. 2008 Jul 15;68(14):5699-705. doi: 10.1158/0008-5472.CAN-07-6862.


Identification of novel human Cdt1-binding proteins by a proteomics approach: proteolytic regulation by APC/CCdh1.

Sugimoto N, Kitabayashi I, Osano S, Tatsumi Y, Yugawa T, Narisawa-Saito M, Matsukage A, Kiyono T, Fujita M.

Mol Biol Cell. 2008 Mar;19(3):1007-21. Epub 2007 Dec 27.


CUB domain-containing protein 1 is a novel regulator of anoikis resistance in lung adenocarcinoma.

Uekita T, Jia L, Narisawa-Saito M, Yokota J, Kiyono T, Sakai R.

Mol Cell Biol. 2007 Nov;27(21):7649-60. Epub 2007 Sep 4.


Basic mechanisms of high-risk human papillomavirus-induced carcinogenesis: roles of E6 and E7 proteins.

Narisawa-Saito M, Kiyono T.

Cancer Sci. 2007 Oct;98(10):1505-11. Epub 2007 Jul 23. Review.


Regulation of Notch1 gene expression by p53 in epithelial cells.

Yugawa T, Handa K, Narisawa-Saito M, Ohno S, Fujita M, Kiyono T.

Mol Cell Biol. 2007 May;27(10):3732-42. Epub 2007 Mar 12.


Efficient immortalization of primary human cells by p16INK4a-specific short hairpin RNA or Bmi-1, combined with introduction of hTERT.

Haga K, Ohno S, Yugawa T, Narisawa-Saito M, Fujita M, Sakamoto M, Galloway DA, Kiyono T.

Cancer Sci. 2007 Feb;98(2):147-54.


HPV16 E6-mediated stabilization of ErbB2 in neoplastic transformation of human cervical keratinocytes.

Narisawa-Saito M, Handa K, Yugawa T, Ohno S, Fujita M, Kiyono T.

Oncogene. 2007 May 10;26(21):2988-96. Epub 2006 Dec 4.


E6AP-dependent degradation of DLG4/PSD95 by high-risk human papillomavirus type 18 E6 protein.

Handa K, Yugawa T, Narisawa-Saito M, Ohno S, Fujita M, Kiyono T.

J Virol. 2007 Feb;81(3):1379-89. Epub 2006 Nov 22.


Deregulation of Cdt1 induces chromosomal damage without rereplication and leads to chromosomal instability.

Tatsumi Y, Sugimoto N, Yugawa T, Narisawa-Saito M, Kiyono T, Fujita M.

J Cell Sci. 2006 Aug 1;119(Pt 15):3128-40. Epub 2006 Jul 11.


Brain-derived neurotrophic factor signal enhances and maintains the expression of AMPA receptor-associated PDZ proteins in developing cortical neurons.

Jourdi H, Iwakura Y, Narisawa-Saito M, Ibaraki K, Xiong H, Watanabe M, Hayashi Y, Takei N, Nawa H.

Dev Biol. 2003 Nov 15;263(2):216-30.


Brain-derived neurotrophic factor upregulates and maintains AMPA receptor currents in neocortical GABAergic neurons.

Nagano T, Yanagawa Y, Obata K, Narisawa-Saito M, Namba H, Otsu Y, Takei N, Nawa H.

Mol Cell Neurosci. 2003 Oct;24(2):340-56.


The C-terminal region of cellular Qin oligomerizes: correlation with oncogenic transformation and transcriptional repression.

Sonderegger CK, Narisawa-Saito M, Vogt PK.

Oncogene. 2003 Apr 3;22(13):1908-15.


Phenotypic down-regulation of glutamate receptor subunit GluR1 in Alzheimer's disease.

Wakabayashi K, Narisawa-Saito M, Iwakura Y, Arai T, Ikeda K, Takahashi H, Nawa H.

Neurobiol Aging. 1999 May-Jun;20(3):287-95.


Brain-derived neurotrophic factor regulates the expression of AMPA receptor proteins in neocortical neurons.

Narisawa-Saito M, Carnahan J, Araki K, Yamaguchi T, Nawa H.

Neuroscience. 1999;88(4):1009-14.


Growth factor-mediated Fyn signaling regulates alpha-amino-3- hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor expression in rodent neocortical neurons.

Narisawa-Saito M, Silva AJ, Yamaguchi T, Hayashi T, Yamamoto T, Nawa H.

Proc Natl Acad Sci U S A. 1999 Mar 2;96(5):2461-6. Erratum in: Proc Natl Acad Sci U S A 1999 May 11;96(10):5890.


Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer's disease.

Narisawa-Saito M, Wakabayashi K, Tsuji S, Takahashi H, Nawa H.

Neuroreport. 1996 Nov 25;7(18):2925-8.


Thy-1 molecule associates with protein tyrosine kinase(s) in rat mesangial cells.

Narisawa-Saito M, Yamanashi Y, Morioka T, Oite T, Shimizu F.

Clin Exp Immunol. 1996 Oct;106(1):86-90.


Thy-1-mediated phosphatidylinositol turnover in cultured rat glomerular mesangial cell.

Narisawa-Saito M, Kimura S, Fujiwara N, Oite T, Shimoji K, Shimizu F.

J Cell Physiol. 1996 Sep;168(3):705-10.


Differential regulation of hippocampal neurotrophins during aging in rats.

Narisawa-Saito M, Nawa H.

J Neurochem. 1996 Sep;67(3):1124-31.


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