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Items: 1 to 50 of 190

1.

Effect of in utero exposure to endocrine disruptors on fetal steroidogenesis governed by the pituitary-gonad axis: a study in rats using different ways of administration.

Kariyazono Y, Taura J, Hattori Y, Ishii Y, Narimatsu S, Fujimura M, Takeda T, Yamada H.

J Toxicol Sci. 2015 Dec;40(6):909-16. doi: 10.2131/jts.40.909.

2.

Functional characterization of cynomolgus monkey UDP-glucuronosyltransferase 1A9.

Yamamoto K, Mukai M, Nagaoka K, Hayashi K, Hichiya H, Okada K, Murata M, Shigeyama M, Narimatsu S, Hanioka N.

Eur J Drug Metab Pharmacokinet. 2014 Sep;39(3):195-202. doi: 10.1007/s13318-014-0177-x. Epub 2014 Jan 28.

PMID:
24470170
3.

Production of hybrid-IgG/IgA plantibodies with neutralizing activity against Shiga toxin 1.

Nakanishi K, Narimatsu S, Ichikawa S, Tobisawa Y, Kurohane K, Niwa Y, Kobayashi H, Imai Y.

PLoS One. 2013 Nov 28;8(11):e80712. doi: 10.1371/journal.pone.0080712. eCollection 2013.

4.

Structural requirements for potent direct inhibition of human cytochrome P450 1A1 by cannabidiol: role of pentylresorcinol moiety.

Yamaori S, Okushima Y, Masuda K, Kushihara M, Katsu T, Narimatsu S, Yamamoto I, Watanabe K.

Biol Pharm Bull. 2013;36(7):1197-203.

5.

Effect of UDP-glucuronosyltransferase 1A8 polymorphism on raloxifene glucuronidation.

Kokawa Y, Kishi N, Jinno H, Tanaka-Kagawa T, Narimatsu S, Hanioka N.

Eur J Pharm Sci. 2013 May 13;49(2):199-205. doi: 10.1016/j.ejps.2013.03.001. Epub 2013 Mar 14.

PMID:
23499758
6.

cDNA cloning and functional analysis of minipig uridine diphosphate-glucuronosyltransferase 1A1.

Miyake Y, Mayumi K, Jinno H, Tanaka-Kagawa T, Narimatsu S, Hanioka N.

Biol Pharm Bull. 2013;36(3):452-61.

7.

Characterization of marmoset CYP2B6: cDNA cloning, protein expression and enzymatic functions.

Mayumi K, Hanioka N, Masuda K, Koeda A, Naito S, Miyata A, Narimatsu S.

Biochem Pharmacol. 2013 Apr 15;85(8):1182-94. doi: 10.1016/j.bcp.2013.01.024. Epub 2013 Feb 5.

PMID:
23395694
8.

Evaluation of animal models for intestinal first-pass metabolism of drug candidates to be metabolized by CYP3A enzymes via in vivo and in vitro oxidation of midazolam and triazolam.

Kuze J, Mutoh T, Takenaka T, Oda N, Hanioka N, Narimatsu S.

Xenobiotica. 2013 Jul;43(7):598-606. doi: 10.3109/00498254.2012.751517. Epub 2013 Jan 3.

PMID:
23282066
9.

Mutants of lymphotoxin-α with augmented cytotoxic activity via TNFR1 for use in cancer therapy.

Morishige T, Yoshioka Y, Narimatsu S, Ikemizu S, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.

Cytokine. 2013 Feb;61(2):578-84. doi: 10.1016/j.cyto.2012.11.005. Epub 2012 Dec 11.

PMID:
23246116
10.

Induction of neurite outgrowth in PC12 cells by artemisinin through activation of ERK and p38 MAPK signaling pathways.

Sarina, Yagi Y, Nakano O, Hashimoto T, Kimura K, Asakawa Y, Zhong M, Narimatsu S, Gohda E.

Brain Res. 2013 Jan 15;1490:61-71. doi: 10.1016/j.brainres.2012.10.059. Epub 2012 Nov 2.

PMID:
23123209
11.

Stereoselective glucuronidation of carvedilol in human liver and intestinal microsomes.

Hanioka N, Tanaka S, Moriguchi Y, Narimatsu S.

Pharmacology. 2012;90(3-4):117-24. doi: 10.1159/000340020. Epub 2012 Jul 18.

PMID:
22814440
12.

Effect of aflatoxin B1 on UDP-glucuronosyltransferase mRNA expression in HepG2 cells.

Hanioka N, Nonaka Y, Saito K, Negishi T, Okamoto K, Kataoka H, Narimatsu S.

Chemosphere. 2012 Oct;89(5):526-9. doi: 10.1016/j.chemosphere.2012.05.039. Epub 2012 Jun 29.

PMID:
22749127
13.

Hydrolysis of di-n-butyl phthalate, butylbenzyl phthalate and di(2-ethylhexyl) phthalate in human liver microsomes.

Hanioka N, Takahara Y, Takahara Y, Tanaka-Kagawa T, Jinno H, Narimatsu S.

Chemosphere. 2012 Nov;89(9):1112-7. doi: 10.1016/j.chemosphere.2012.05.095. Epub 2012 Jun 25.

PMID:
22739543
14.

Suppression of nanosilica particle-induced inflammation by surface modification of the particles.

Morishige T, Yoshioka Y, Inakura H, Tanabe A, Narimatsu S, Yao X, Monobe Y, Imazawa T, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.

Arch Toxicol. 2012 Aug;86(8):1297-307. doi: 10.1007/s00204-012-0823-5. Epub 2012 Mar 15.

PMID:
22418595
15.

The effects of N-glycosylation on the glucuronidation of zidovudine and morphine by UGT2B7 expressed in HEK293 cells.

Nagaoka K, Hanioka N, Ikushiro S, Yamano S, Narimatsu S.

Drug Metab Pharmacokinet. 2012;27(4):388-97. Epub 2012 Jan 13.

16.

Structure-activity relationship of T-cell receptors based on alanine scanning.

Narimatsu S, Yoshioka Y, Morishige T, Yao X, Tsunoda S, Tsutsumi Y, Nishimura MI, Mukai Y, Okada N, Nakagawa S.

Biochem Biophys Res Commun. 2011 Dec 2;415(4):558-62. doi: 10.1016/j.bbrc.2011.10.092. Epub 2011 Oct 31.

PMID:
22079637
17.

Characterization of inhibitory effects of perfluorooctane sulfonate on human hepatic cytochrome P450 isoenzymes: focusing on CYP2A6.

Narimatsu S, Nakanishi R, Hanioka N, Saito K, Kataoka H.

Chem Biol Interact. 2011 Nov 15;194(2-3):120-6. doi: 10.1016/j.cbi.2011.09.002. Epub 2011 Sep 19.

PMID:
21964418
18.

Expression and inducibility of UDP-glucuronosyltransferase 1As in MCF-7 human breast carcinoma cells.

Hanioka N, Iwabu H, Hanafusa H, Nakada S, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2012 Mar;110(3):253-8. doi: 10.1111/j.1742-7843.2011.00790.x. Epub 2011 Oct 10.

19.

Lysine-deficient lymphotoxin-α mutant for site-specific PEGylation.

Narimatsu S, Yoshioka Y, Watanabe H, Masano T, Morishige T, Yao X, Tanabe A, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.

Cytokine. 2011 Nov;56(2):489-93. doi: 10.1016/j.cyto.2011.08.021. Epub 2011 Aug 25.

PMID:
21871814
20.

Comparison of real-time reverse-transcription loop-mediated isothermal amplification and real-time reverse-transcription polymerase chain reaction for detection of noroviruses in municipal wastewater.

Suzuki Y, Narimatsu S, Furukawa T, Iwakiri A, Miura M, Yamamoto S, Katayama H.

J Biosci Bioeng. 2011 Oct;112(4):369-72. doi: 10.1016/j.jbiosc.2011.06.012. Epub 2011 Aug 6.

PMID:
21821471
21.

Tumor vascular targeted delivery of polymer-conjugated adenovirus vector for cancer gene therapy.

Yao X, Yoshioka Y, Morishige T, Eto Y, Narimatsu S, Kawai Y, Mizuguchi H, Gao JQ, Mukai Y, Okada N, Nakagawa S.

Mol Ther. 2011 Sep;19(9):1619-25. doi: 10.1038/mt.2011.112. Epub 2011 Jun 14.

22.

Effect of UDP-glucuronosyltransferase 2B15 polymorphism on bisphenol A glucuronidation.

Hanioka N, Oka H, Nagaoka K, Ikushiro S, Narimatsu S.

Arch Toxicol. 2011 Nov;85(11):1373-81. doi: 10.1007/s00204-011-0690-5. Epub 2011 Mar 15.

PMID:
21404072
23.

Influence of CYP2C8*13 and CYP2C8*14 alleles on amiodarone N-deethylation.

Hanioka N, Matsumoto K, Saito Y, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2011 May;108(5):359-62. doi: 10.1111/j.1742-7843.2010.00669.x. Epub 2011 Jan 31. No abstract available.

24.

Regio- and stereoselective oxidation of propranolol enantiomers by human CYP2D6, cynomolgus monkey CYP2D17 and marmoset CYP2D19.

Narimatsu S, Nakata T, Shimizudani T, Nagaoka K, Nakura H, Masuda K, Katsu T, Koeda A, Naito S, Yamano S, Miyata A, Hanioka N.

Chem Biol Interact. 2011 Feb 1;189(3):146-52. doi: 10.1016/j.cbi.2010.12.014. Epub 2010 Dec 22.

PMID:
21184751
25.

Expression levels of drug-metabolizing enzyme, transporter, and nuclear receptor mRNAs in a novel three-dimensional culture system for human hepatocytes using micro-space plates.

Nishimura M, Ejiri Y, Kishimoto S, Suzuki S, Satoh T, Horie T, Narimatsu S, Naito S.

Drug Metab Pharmacokinet. 2011;26(2):137-44. Epub 2010 Nov 26.

26.

Optimized PEGylated adenovirus vector reduces the anti-vector humoral immune response against adenovirus and induces a therapeutic effect against metastatic lung cancer.

Eto Y, Yoshioka Y, Ishida T, Yao X, Morishige T, Narimatsu S, Mizuguchi H, Mukai Y, Okada N, Kiwada H, Nakagawa S.

Biol Pharm Bull. 2010;33(9):1540-4.

27.

Determination of polycyclic aromatic hydrocarbons in food samples by automated on-line in-tube solid-phase microextraction coupled with high-performance liquid chromatography-fluorescence detection.

Ishizaki A, Saito K, Hanioka N, Narimatsu S, Kataoka H.

J Chromatogr A. 2010 Aug 27;1217(35):5555-63. doi: 10.1016/j.chroma.2010.06.068. Epub 2010 Jun 30.

PMID:
20637468
28.

Functional characterization of human and cynomolgus monkey UDP-glucuronosyltransferase 1A1 enzymes.

Hanioka N, Tanabe N, Jinno H, Tanaka-Kagawa T, Nagaoka K, Naito S, Koeda A, Narimatsu S.

Life Sci. 2010 Aug 14;87(7-8):261-8. doi: 10.1016/j.lfs.2010.07.001. Epub 2010 Jul 8.

PMID:
20620155
29.

Secretion of albumin and induction of CYP1A2 and CYP3A4 in novel three-dimensional culture system for human hepatocytes using micro-space plate.

Nishimura M, Hagi M, Ejiri Y, Kishimoto S, Horie T, Narimatsu S, Naito S.

Drug Metab Pharmacokinet. 2010;25(3):236-42.

30.

The effect of surface modification of amorphous silica particles on NLRP3 inflammasome mediated IL-1beta production, ROS production and endosomal rupture.

Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Narimatsu S, Monobe Y, Imazawa T, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S.

Biomaterials. 2010 Sep;31(26):6833-42. doi: 10.1016/j.biomaterials.2010.05.036. Epub 2010 Jun 18.

PMID:
20561679
31.

Adenovirus vector covalently conjugated to polyethylene glycol with a cancer-specific promoter suppresses the tumor growth through systemic administration.

Yao X, Yoshioka Y, Morishige T, Eto Y, Narimatsu S, Mizuguchi H, Mukai Y, Okada N, Nakagawa S.

Biol Pharm Bull. 2010;33(6):1073-6.

32.

Functional characterization of CYP2C8.13 and CYP2C8.14: catalytic activities toward paclitaxel.

Hanioka N, Matsumoto K, Saito Y, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2010 Jul;107(1):565-9. doi: 10.1111/j.1742-7843.2010.00543.x. Epub 2010 Feb 10.

33.

Functional characterization of human cytochrome P4502E1 allelic variants: in vitro metabolism of benzene and toluene by recombinant enzymes expressed in yeast cells.

Hanioka N, Yamamoto M, Tanaka-Kagawa T, Jinno H, Narimatsu S.

Arch Toxicol. 2010 May;84(5):363-71. doi: 10.1007/s00204-009-0504-1. Epub 2009 Dec 24.

PMID:
20033806
35.

Comparative study of the oxidation of propranolol enantiomers in hepatic and small intestinal microsomes from cynomolgus and marmoset monkeys.

Shimizudani T, Nagaoka K, Hanioka N, Yamano S, Narimatsu S.

Chem Biol Interact. 2010 Jan 5;183(1):67-78. doi: 10.1016/j.cbi.2009.10.007.

PMID:
19853591
36.

Separate evaluation of intestinal and hepatic metabolism of three benzodiazepines in rats with cannulated portal and jugular veins: comparison with the profile in non-cannulated mice.

Kuze J, Mutoh T, Takenaka T, Morisaki K, Nakura H, Hanioka N, Narimatsu S.

Xenobiotica. 2009 Nov;39(11):871-80. doi: 10.3109/00498250903215382.

PMID:
19845438
37.

Tissue-specific mRNA expression profiles of drug-metabolizing enzymes and transporters in the cynomolgus monkey.

Nishimura M, Koeda A, Morikawa H, Satoh T, Narimatsu S, Naito S.

Drug Metab Pharmacokinet. 2009;24(2):139-44.

38.

Determination of aflatoxins in food samples by automated on-line in-tube solid-phase microextraction coupled with liquid chromatography-mass spectrometry.

Nonaka Y, Saito K, Hanioka N, Narimatsu S, Kataoka H.

J Chromatogr A. 2009 May 15;1216(20):4416-22. doi: 10.1016/j.chroma.2009.03.035. Epub 2009 Mar 18.

PMID:
19328492
39.

Functional characterization of CYP3A4.16: catalytic activities toward midazolam and carbamazepine.

Maekawa K, Yoshimura T, Saito Y, Fujimura Y, Aohara F, Emoto C, Iwasaki K, Hanioka N, Narimatsu S, Niwa T, Sawada J.

Xenobiotica. 2009 Feb;39(2):140-7. doi: 10.1080/00498250802617746.

PMID:
19255940
40.

The mechanism causing the difference in kinetic properties between rat CYP2D4 and human CYP2D6 in the oxidation of dextromethorphan and bufuralol.

Narimatsu S, Kazamori D, Masuda K, Katsu T, Funae Y, Naito S, Nakura H, Yamano S, Hanioka N.

Biochem Pharmacol. 2009 Mar 1;77(5):920-31. doi: 10.1016/j.bcp.2008.11.006. Epub 2008 Nov 17.

PMID:
19059219
41.

Human UDP-glucuronosyltransferase isoforms involved in bisphenol A glucuronidation.

Hanioka N, Naito T, Narimatsu S.

Chemosphere. 2008 Dec;74(1):33-6. doi: 10.1016/j.chemosphere.2008.09.053. Epub 2008 Nov 5.

PMID:
18990428
43.

Stereoselective glucuronidation of propranolol in human and cynomolgus monkey liver microsomes: role of human hepatic UDP-glucuronosyltransferase isoforms, UGT1A9, UGT2B4 and UGT2B7.

Hanioka N, Hayashi K, Shimizudani T, Nagaoka K, Koeda A, Naito S, Narimatsu S.

Pharmacology. 2008;82(4):293-303. doi: 10.1159/000165100. Epub 2008 Oct 21.

PMID:
18936551
44.

A caffeine-sensitive membrane electrode: previous misleading report and present approach.

Katsu T, Tsunamoto Y, Hanioka N, Komagoe K, Masuda K, Narimatsu S.

Anal Chim Acta. 2008 Jul 14;620(1-2):50-4. doi: 10.1016/j.aca.2008.05.027. Epub 2008 May 21.

45.

Influence of CYP2C19*18 and CYP2C19*19 alleles on omeprazole 5-hydroxylation: in vitro functional analysis of recombinant enzymes expressed in Saccharomyces cerevisiae.

Hanioka N, Tsuneto Y, Saito Y, Maekawa K, Sawada J, Narimatsu S.

Basic Clin Pharmacol Toxicol. 2008 Apr;102(4):388-93. doi: 10.1111/j.1742-7843.2008.00222.x. Epub 2008 Feb 29.

46.
47.
48.

Interaction of bisphenol A with human UDP-glucuronosyltransferase 1A6 enzyme.

Hanioka N, Takeda Y, Tanaka-Kagawa T, Hayashi K, Jinno H, Narimatsu S.

Environ Toxicol. 2008 Jun;23(3):407-12. doi: 10.1002/tox.20345.

PMID:
18214896
49.

The roles of amino acid residues at positions 216 and 219 in the structural stability and metabolic functions of rat cytochrome P450 2D1 and 2D2.

Narimatsu S, Kiryu K, Yonemoto R, Yoshino M, Kobatake M, Kazamori D, Hagino S, Masuda K, Katsu T, Asanuma M, Kumamoto T, Ishikawa T, Funae Y, Yamano S, Hanioka N, Naito S.

Chem Biol Interact. 2008 Mar 10;172(1):11-21. doi: 10.1016/j.cbi.2007.11.010. Epub 2007 Nov 28.

PMID:
18191824
50.

Oxidation of 5-methoxy-N,N-diisopropyltryptamine in rat liver microsomes and recombinant cytochrome P450 enzymes.

Narimatsu S, Yonemoto R, Masuda K, Katsu T, Asanuma M, Kamata T, Katagi M, Tsuchihashi H, Kumamoto T, Ishikawa T, Naito S, Yamano S, Hanioka N.

Biochem Pharmacol. 2008 Feb 1;75(3):752-60. Epub 2007 Sep 29.

PMID:
17980859

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