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Moderate Intensity Resistive Training Reduces Oxidative Stress and Improves Muscle Mass and Function in Older Individuals.

Vezzoli A, Mrakic-Sposta S, Montorsi M, Porcelli S, Vago P, Cereda F, Longo S, Maggio M, Narici M.

Antioxidants (Basel). 2019 Sep 26;8(10). pii: E431. doi: 10.3390/antiox8100431.


The usefulness of muscle architecture assessed with ultrasound to identify hospitalized older adults with physical decline.

Aubertin-Leheudre M, Martel D, Narici M, Bonnefoy M.

Exp Gerontol. 2019 Oct 1;125:110678. doi: 10.1016/j.exger.2019.110678. Epub 2019 Jul 31.


Bouncing Back! Counteracting Muscle Aging With Plyometric Muscle Loading.

Franchi MV, Monti E, Carter A, Quinlan JI, Herrod PJJ, Reeves ND, Narici MV.

Front Physiol. 2019 Mar 5;10:178. doi: 10.3389/fphys.2019.00178. eCollection 2019.


Tensiomyography detects early hallmarks of bed-rest-induced atrophy before changes in muscle architecture.

Šimunič B, Koren K, Rittweger J, Lazzer S, Reggiani C, Rejc E, Pišot R, Narici M, Degens H.

J Appl Physiol (1985). 2019 Apr 1;126(4):815-822. doi: 10.1152/japplphysiol.00880.2018. Epub 2019 Jan 24.


Recovery from 6-month spaceflight at the International Space Station: muscle-related stress into a proinflammatory setting.

Capri M, Morsiani C, Santoro A, Moriggi M, Conte M, Martucci M, Bellavista E, Fabbri C, Giampieri E, Albracht K, Flück M, Ruoss S, Brocca L, Canepari M, Longa E, Di Giulio I, Bottinelli R, Cerretelli P, Salvioli S, Gelfi C, Franceschi C, Narici M, Rittweger J.

FASEB J. 2019 Apr;33(4):5168-5180. doi: 10.1096/fj.201801625R. Epub 2019 Jan 8.


Diffusion tensor imaging and diffusion modeling: Application to monitoring changes in the medial gastrocnemius in disuse atrophy induced by unilateral limb suspension.

Malis V, Sinha U, Csapo R, Narici M, Smitaman E, Sinha S.

J Magn Reson Imaging. 2019 Jun;49(6):1655-1664. doi: 10.1002/jmri.26295. Epub 2018 Dec 19.


Erratum: Author Correction: Sarcolab pilot study into skeletal muscle's adaptation to longterm spaceflight.

Rittweger J, Albracht K, Flück M, Ruoss S, Brocca L, Longa E, Moriggi M, Seynnes O, Di Giulio I, Tenori L, Vignoli A, Capri M, Gelfi C, Luchinat C, Franceschi C, Bottinelli R, Cerretelli P, Narici M.

NPJ Microgravity. 2018 Oct 24;4:23. doi: 10.1038/s41526-018-0058-8. eCollection 2018.


A double-blind placebo controlled trial into the impacts of HMB supplementation and exercise on free-living muscle protein synthesis, muscle mass and function, in older adults.

Din USU, Brook MS, Selby A, Quinlan J, Boereboom C, Abdullah H, Franchi M, Narici MV, Phillips BE, Williams JW, Rathmacher JA, Wilkinson DJ, Atherton PJ, Smith K.

Clin Nutr. 2019 Oct;38(5):2071-2078. doi: 10.1016/j.clnu.2018.09.025. Epub 2018 Sep 27.


Sarcolab pilot study into skeletal muscle's adaptation to long-term spaceflight.

Rittweger J, Albracht K, Flück M, Ruoss S, Brocca L, Longa E, Moriggi M, Seynnes O, Di Giulio I, Tenori L, Vignoli A, Capri M, Gelfi C, Luchinat C, Francheschi C, Bottinelli R, Cerretelli P, Narici M.

NPJ Microgravity. 2018 Sep 17;4:18. doi: 10.1038/s41526-018-0052-1. eCollection 2018. Erratum in: NPJ Microgravity. 2018 Oct 24;4:23.


Developing a toolkit for the assessment and monitoring of musculoskeletal ageing.

Kemp GJ, Birrell F, Clegg PD, Cuthbertson DJ, De Vito G, van Dieën JH, Del Din S, Eastell R, Garnero P, Goljanek-Whysall K, Hackl M, Hodgson R, Jackson MJ, Lord S, Mazzà C, McArdle A, McCloskey EV, Narici M, Peffers MJ, Schiaffino S, Mathers JC.

Age Ageing. 2018 Sep 1;47(suppl_4):iv1-iv19. doi: 10.1093/ageing/afy143. Review.


Muscle Architecture Assessment: Strengths, Shortcomings and New Frontiers of in Vivo Imaging Techniques.

Franchi MV, Raiteri BJ, Longo S, Sinha S, Narici MV, Csapo R.

Ultrasound Med Biol. 2018 Dec;44(12):2492-2504. doi: 10.1016/j.ultrasmedbio.2018.07.010. Epub 2018 Sep 2. Review.


Handgrip Strength Cannot Be Assumed a Proxy for Overall Muscle Strength.

Yeung SSY, Reijnierse EM, Trappenburg MC, Hogrel JY, McPhee JS, Piasecki M, Sipila S, Salpakoski A, Butler-Browne G, Pääsuke M, Gapeyeva H, Narici MV, Meskers CGM, Maier AB.

J Am Med Dir Assoc. 2018 Aug;19(8):703-709. doi: 10.1016/j.jamda.2018.04.019. Epub 2018 Jun 20.


Assessing sarcopenia with vastus lateralis muscle ultrasound: an operative protocol.

Ticinesi A, Narici MV, Lauretani F, Nouvenne A, Colizzi E, Mantovani M, Corsonello A, Landi F, Meschi T, Maggio M.

Aging Clin Exp Res. 2018 Dec;30(12):1437-1443. doi: 10.1007/s40520-018-0958-1. Epub 2018 Apr 26.


Shear strain rate from phase contrast velocity encoded MRI: Application to study effects of aging in the medial gastrocnemius muscle.

Sinha U, Malis V, Csapo R, Narici M, Sinha S.

J Magn Reson Imaging. 2018 Nov;48(5):1351-1357. doi: 10.1002/jmri.26030. Epub 2018 Apr 1.


Effects of 14 days of bed rest and following physical training on metabolic cost, mechanical work, and efficiency during walking in older and young healthy males.

Floreani M, Rejc E, Taboga P, Ganzini A, Pišot R, Šimunič B, Biolo G, Reggiani C, Passaro A, Narici M, Rittweger J, di Prampero PE, Lazzer S.

PLoS One. 2018 Mar 12;13(3):e0194291. doi: 10.1371/journal.pone.0194291. eCollection 2018.


Regional regulation of focal adhesion kinase after concentric and eccentric loading is related to remodelling of human skeletal muscle.

Franchi MV, Ruoss S, Valdivieso P, Mitchell KW, Smith K, Atherton PJ, Narici MV, Flück M.

Acta Physiol (Oxf). 2018 Jul;223(3):e13056. doi: 10.1111/apha.13056. Epub 2018 Mar 3.


Loss of maximal explosive power of lower limbs after 2 weeks of disuse and incomplete recovery after retraining in older adults.

Rejc E, Floreani M, Taboga P, Botter A, Toniolo L, Cancellara L, Narici M, Šimunič B, Pišot R, Biolo G, Passaro A, Rittweger J, Reggiani C, Lazzer S.

J Physiol. 2018 Feb 15;596(4):647-665. doi: 10.1113/JP274772. Epub 2018 Jan 19.


Dysregulation of C-X-C motif ligand 10 during aging and association with cognitive performance.

Bradburn S, McPhee J, Bagley L, Carroll M, Slevin M, Al-Shanti N, Barnouin Y, Hogrel JY, Pääsuke M, Gapeyeva H, Maier A, Sipilä S, Narici M, Robinson A, Mann D, Payton A, Pendleton N, Butler-Browne G, Murgatroyd C.

Neurobiol Aging. 2018 Mar;63:54-64. doi: 10.1016/j.neurobiolaging.2017.11.009. Epub 2017 Nov 23.


Editorial: Physiology and Clinical Potential of Eccentric Exercise.

Franchi MV, Mitchell KW, Hoppeler H, Narici MV.

Front Physiol. 2017 Nov 3;8:891. doi: 10.3389/fphys.2017.00891. eCollection 2017. No abstract available.


Response to the letter to editor by Dankel et al. 2017 "Changes in muscle size via MRI and ultrasound: Are they equivalent?"

Franchi MV, Greenhaff PL, Narici MV.

Scand J Med Sci Sports. 2018 Apr;28(4):1469. doi: 10.1111/sms.13010. Epub 2017 Nov 22. No abstract available.


Muscle and Tendon Contributions to Reduced Rate of Torque Development in Healthy Older Males.

Quinlan JI, Maganaris CN, Franchi MV, Smith K, Atherton PJ, Szewczyk NJ, Greenhaff PL, Phillips BE, Blackwell JI, Boereboom C, Williams JP, Lund J, Narici MV.

J Gerontol A Biol Sci Med Sci. 2018 Mar 14;73(4):539-545. doi: 10.1093/gerona/glx149.


Muscle thickness correlates to muscle cross-sectional area in the assessment of strength training-induced hypertrophy.

Franchi MV, Longo S, Mallinson J, Quinlan JI, Taylor T, Greenhaff PL, Narici MV.

Scand J Med Sci Sports. 2018 Mar;28(3):846-853. doi: 10.1111/sms.12961. Epub 2017 Sep 21.


Skeletal Muscle Remodeling in Response to Eccentric vs. Concentric Loading: Morphological, Molecular, and Metabolic Adaptations.

Franchi MV, Reeves ND, Narici MV.

Front Physiol. 2017 Jul 4;8:447. doi: 10.3389/fphys.2017.00447. eCollection 2017. Review.


Circulating levels of dickkopf-1, osteoprotegerin and sclerostin are higher in old compared with young men and women and positively associated with whole-body bone mineral density in older adults.

Coulson J, Bagley L, Barnouin Y, Bradburn S, Butler-Browne G, Gapeyeva H, Hogrel JY, Maden-Wilkinson T, Maier AB, Meskers C, Murgatroyd C, Narici M, Pääsuke M, Sassano L, Sipilä S, Al-Shanti N, Stenroth L, Jones DA, McPhee JS.

Osteoporos Int. 2017 Sep;28(9):2683-2689. doi: 10.1007/s00198-017-4104-2. Epub 2017 Jun 5.


Relationship of changes in strain rate indices estimated from velocity-encoded MR imaging to loss of muscle force following disuse atrophy.

Malis V, Sinha U, Csapo R, Narici M, Sinha S.

Magn Reson Med. 2018 Feb;79(2):912-922. doi: 10.1002/mrm.26759. Epub 2017 May 30.


Neuromuscular deconditioning with disuse: should we live more on our nerves?

Narici MV.

J Physiol. 2017 Jul 1;595(13):4127. doi: 10.1113/JP274347. Epub 2017 May 25. No abstract available.


Structure and function of human muscle fibres and muscle proteome in physically active older men.

Brocca L, McPhee JS, Longa E, Canepari M, Seynnes O, De Vito G, Pellegrino MA, Narici M, Bottinelli R.

J Physiol. 2017 Jul 15;595(14):4823-4844. doi: 10.1113/JP274148. Epub 2017 Jun 5.


Coupling between skeletal muscle fiber size and capillarization is maintained during healthy aging.

Barnouin Y, McPhee JS, Butler-Browne G, Bosutti A, De Vito G, Jones DA, Narici M, Behin A, Hogrel JY, Degens H.

J Cachexia Sarcopenia Muscle. 2017 Aug;8(4):647-659. doi: 10.1002/jcsm.12194. Epub 2017 Apr 5.


Eccentric Exercise and the Critically Ill Patient.

Mitchell WK, Taivassalo T, Narici MV, Franchi MV.

Front Physiol. 2017 Feb 28;8:120. doi: 10.3389/fphys.2017.00120. eCollection 2017. No abstract available.


Muscle Ultrasound and Sarcopenia in Older Individuals: A Clinical Perspective.

Ticinesi A, Meschi T, Narici MV, Lauretani F, Maggio M.

J Am Med Dir Assoc. 2017 Apr 1;18(4):290-300. doi: 10.1016/j.jamda.2016.11.013. Epub 2017 Feb 13. Review.


Computerized cognitive training and brain derived neurotrophic factor during bed rest: mechanisms to protect individual during acute stress.

Passaro A, Soavi C, Marusic U, Rejc E, Sanz JM, Morieri ML, Nora ED, Kavcic V, Narici MV, Reggiani C, Biolo G, Zuliani G, Lazzer S, Pišot R.

Aging (Albany NY). 2017 Feb 3;9(2):393-407. doi: 10.18632/aging.101166.


Assessment of maximal handgrip strength: how many attempts are needed?

Reijnierse EM, de Jong N, Trappenburg MC, Blauw GJ, Butler-Browne G, Gapeyeva H, Hogrel JY, McPhee JS, Narici MV, Sipilä S, Stenroth L, van Lummel RC, Pijnappels M, Meskers CGM, Maier AB.

J Cachexia Sarcopenia Muscle. 2017 Jun;8(3):466-474. doi: 10.1002/jcsm.12181. Epub 2017 Feb 2.


Association between osteocalcin and cognitive performance in healthy older adults.

Bradburn S, McPhee JS, Bagley L, Sipila S, Stenroth L, Narici MV, Pääsuke M, Gapeyeva H, Osborne G, Sassano L, Meskers CG, Maier AB, Hogrel JY, Barnouin Y, Butler-Browne G, Murgatroyd C.

Age Ageing. 2016 Nov;45(6):844-849. Epub 2016 Aug 11.


Anabolic resistance assessed by oral stable isotope ingestion following bed rest in young and older adult volunteers: Relationships with changes in muscle mass.

Biolo G, Pišot R, Mazzucco S, Di Girolamo FG, Situlin R, Lazzer S, Grassi B, Reggiani C, Passaro A, Rittweger J, Gasparini M, Šimunič B, Narici M.

Clin Nutr. 2017 Oct;36(5):1420-1426. doi: 10.1016/j.clnu.2016.09.019. Epub 2016 Sep 30.


Neural Activation During Submaximal Contractions Seems More Reflective of Neuromuscular Ageing than Maximal Voluntary Activation.

Scaglioni G, Narici MV, Martin A.

Front Aging Neurosci. 2016 Feb 25;8:19. doi: 10.3389/fnagi.2016.00019. eCollection 2016.


Fascicle length does increase in response to longitudinal resistance training and in a contraction-mode specific manner.

Franchi MV, Atherton PJ, Maganaris CN, Narici MV.

Springerplus. 2016 Jan 28;5:94. doi: 10.1186/s40064-015-1548-8. eCollection 2016. No abstract available.


Greater loss in muscle mass and function but smaller metabolic alterations in older compared with younger men following 2 wk of bed rest and recovery.

Pišot R, Marusic U, Biolo G, Mazzucco S, Lazzer S, Grassi B, Reggiani C, Toniolo L, di Prampero PE, Passaro A, Narici M, Mohammed S, Rittweger J, Gasparini M, Gabrijelčič Blenkuš M, Šimunič B.

J Appl Physiol (1985). 2016 Apr 15;120(8):922-9. doi: 10.1152/japplphysiol.00858.2015. Epub 2016 Jan 28.


Muscle structural assembly and functional consequences.

Narici M, Franchi M, Maganaris C.

J Exp Biol. 2016 Jan;219(Pt 2):276-84. doi: 10.1242/jeb.128017. Review.


Local trauma in human patellar tendon leads to widespread changes in the tendon gene expression.

Heinemeier KM, Lorentzen MP, Jensen JK, Schjerling P, Seynnes OR, Narici MV, Kjaer M.

J Appl Physiol (1985). 2016 May 1;120(9):1000-10. doi: 10.1152/japplphysiol.00870.2015. Epub 2016 Jan 14.


Early structural remodeling and deuterium oxide-derived protein metabolic responses to eccentric and concentric loading in human skeletal muscle.

Franchi MV, Wilkinson DJ, Quinlan JI, Mitchell WK, Lund JN, Williams JP, Reeves ND, Smith K, Atherton PJ, Narici MV.

Physiol Rep. 2015 Nov;3(11). pii: e12593. doi: 10.14814/phy2.12593.


Single muscle fibre contractile properties differ between body-builders, power athletes and control subjects.

Meijer JP, Jaspers RT, Rittweger J, Seynnes OR, Kamandulis S, Brazaitis M, Skurvydas A, Pišot R, Šimunič B, Narici MV, Degens H.

Exp Physiol. 2015 Nov;100(11):1331-41. doi: 10.1113/EP085267. Epub 2015 Oct 18.


Human skeletal muscle fibre contractile properties and proteomic profile: adaptations to 3 weeks of unilateral lower limb suspension and active recovery.

Brocca L, Longa E, Cannavino J, Seynnes O, de Vito G, McPhee J, Narici M, Pellegrino MA, Bottinelli R.

J Physiol. 2015 Dec 15;593(24):5361-85. doi: 10.1113/JP271188.


Serum albumin and muscle measures in a cohort of healthy young and old participants.

Reijnierse EM, Trappenburg MC, Leter MJ, Sipilä S, Stenroth L, Narici MV, Hogrel JY, Butler-Browne G, McPhee JS, Pääsuke M, Gapeyeva H, Meskers CG, Maier AB.

Age (Dordr). 2015 Oct;37(5):88. doi: 10.1007/s11357-015-9825-6. Epub 2015 Aug 27.


Effects of a vitamin D and leucine-enriched whey protein nutritional supplement on measures of sarcopenia in older adults, the PROVIDE study: a randomized, double-blind, placebo-controlled trial.

Bauer JM, Verlaan S, Bautmans I, Brandt K, Donini LM, Maggio M, McMurdo ME, Mets T, Seal C, Wijers SL, Ceda GP, De Vito G, Donders G, Drey M, Greig C, Holmbäck U, Narici M, McPhee J, Poggiogalle E, Power D, Scafoglieri A, Schultz R, Sieber CC, Cederholm T.

J Am Med Dir Assoc. 2015 Sep 1;16(9):740-7. doi: 10.1016/j.jamda.2015.05.021. Epub 2015 Jul 10.


The prevalence of malnutrition according to the new ESPEN definition in four diverse populations.

Rojer AG, Kruizenga HM, Trappenburg MC, Reijnierse EM, Sipilä S, Narici MV, Hogrel JY, Butler-Browne G, McPhee JS, Pääsuke M, Meskers CG, Maier AB, de van der Schueren MA.

Clin Nutr. 2016 Jun;35(3):758-62. doi: 10.1016/j.clnu.2015.06.005. Epub 2015 Jun 20.


Alpine Skiing With total knee ArthroPlasty (ASWAP): metabolism, inflammation, and skeletal muscle fiber characteristics.

Kristensen M, Pötzelsberger B, Scheiber P, Bergdahl A, Hansen CN, Andersen JL, Narici M, Salvioli S, Conte M, Müller E, Dela F.

Scand J Med Sci Sports. 2015 Aug;25 Suppl 2:40-8. doi: 10.1111/sms.12478.


Alpine Skiing With total knee ArthroPlasty (ASWAP): impact on molecular and architectural features of musculo-skeletal ageing.

Narici M, Conte M, Salvioli S, Franceschi C, Selby A, Dela F, Rieder F, Kösters A, Müller E.

Scand J Med Sci Sports. 2015 Aug;25 Suppl 2:33-9. doi: 10.1111/sms.12458.


The Impact of Different Diagnostic Criteria on the Prevalence of Sarcopenia in Healthy Elderly Participants and Geriatric Outpatients.

Reijnierse EM, Trappenburg MC, Leter MJ, Blauw GJ, Sipilä S, Sillanpää E, Narici MV, Hogrel JY, Butler-Browne G, McPhee JS, Gapeyeva H, Pääsuke M, de van der Schueren MA, Meskers CG, Maier AB.

Gerontology. 2015;61(6):491-6. doi: 10.1159/000377699. Epub 2015 Apr 2.


Plantarflexor Muscle-Tendon Properties are Associated With Mobility in Healthy Older Adults.

Stenroth L, Sillanpää E, McPhee JS, Narici MV, Gapeyeva H, Pääsuke M, Barnouin Y, Hogrel JY, Butler-Browne G, Bijlsma A, Meskers CG, Maier AB, Finni T, Sipilä S.

J Gerontol A Biol Sci Med Sci. 2015 Aug;70(8):996-1002. doi: 10.1093/gerona/glv011. Epub 2015 Mar 1.


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