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Items: 8


USP22 interacts with PALB2 and promotes chemotherapy resistance via homologous recombination of DNA double strand breaks.

Nardi IK, Stark JM, Larsen A, Salgia R, Raz DJ.

Mol Cancer Res. 2019 Nov 4. pii: molcanres.0053.2019. doi: 10.1158/1541-7786.MCR-19-0053. [Epub ahead of print]


Targeting USP22 Suppresses Tumorigenicity and Enhances Cisplatin Sensitivity Through ALDH1A3 Downregulation in Cancer-Initiating Cells from Lung Adenocarcinoma.

Yun X, Zhang K, Wang J, Pangeni RP, Yang L, Bonner M, Wu J, Wang J, Nardi IK, Gao M, Raz DJ.

Mol Cancer Res. 2018 Jul;16(7):1161-1171. doi: 10.1158/1541-7786.MCR-18-0042. Epub 2018 May 2.


Differential Binding Partners of the Mis18α/β YIPPEE Domains Regulate Mis18 Complex Recruitment to Centromeres.

Stellfox ME, Nardi IK, Knippler CM, Foltz DR.

Cell Rep. 2016 Jun 7;15(10):2127-2135. doi: 10.1016/j.celrep.2016.05.004. Epub 2016 May 26.


Licensing of Centromeric Chromatin Assembly through the Mis18α-Mis18β Heterotetramer.

Nardi IK, Zasadzińska E, Stellfox ME, Knippler CM, Foltz DR.

Mol Cell. 2016 Mar 3;61(5):774-787. doi: 10.1016/j.molcel.2016.02.014.


The mitotic origin of chromosomal instability.

Bakhoum SF, Silkworth WT, Nardi IK, Nicholson JM, Compton DA, Cimini D.

Curr Biol. 2014 Feb 17;24(4):R148-9. doi: 10.1016/j.cub.2014.01.019. No abstract available.


Timing of centrosome separation is important for accurate chromosome segregation.

Silkworth WT, Nardi IK, Paul R, Mogilner A, Cimini D.

Mol Biol Cell. 2012 Feb;23(3):401-11. doi: 10.1091/mbc.E11-02-0095. Epub 2011 Nov 30.


Computer simulations predict that chromosome movements and rotations accelerate mitotic spindle assembly without compromising accuracy.

Paul R, Wollman R, Silkworth WT, Nardi IK, Cimini D, Mogilner A.

Proc Natl Acad Sci U S A. 2009 Sep 15;106(37):15708-13. doi: 10.1073/pnas.0908261106. Epub 2009 Aug 26.


Multipolar spindle pole coalescence is a major source of kinetochore mis-attachment and chromosome mis-segregation in cancer cells.

Silkworth WT, Nardi IK, Scholl LM, Cimini D.

PLoS One. 2009 Aug 10;4(8):e6564. doi: 10.1371/journal.pone.0006564.

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