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Items: 42


Interaction of Bacillus subtilis GabR with the gabTD promoter: role of repeated sequences and effect of GABA in transcriptional activation.

Nardella C, Barile A, di Salvo ML, Milano T, Pascarella S, Tramonti A, Contestabile R.

FEBS J. 2020 Mar 9. doi: 10.1111/febs.15286. [Epub ahead of print]


Allosteric feedback inhibition of pyridoxine 5'-phosphate oxidase from Escherichia coli.

Barile A, Tramonti A, di Salvo ML, Nogués I, Nardella C, Malatesta F, Contestabile R.

J Biol Chem. 2019 Oct 25;294(43):15593-15603. doi: 10.1074/jbc.RA119.009697. Epub 2019 Sep 4.


Isolation of a Complex Formed Between Acinetobacter baumannii HemA and HemL, Key Enzymes of Tetrapyrroles Biosynthesis.

Nardella C, Boi D, di Salvo ML, Barile A, Stetefeld J, Tramonti A, Contestabile R.

Front Mol Biosci. 2019 Feb 26;6:6. doi: 10.3389/fmolb.2019.00006. eCollection 2019.


Human Cytosolic and Mitochondrial Serine Hydroxymethyltransferase Isoforms in Comparison: Full Kinetic Characterization and Substrate Inhibition Properties.

Tramonti A, Nardella C, di Salvo ML, Barile A, Cutruzzolà F, Contestabile R.

Biochemistry. 2018 Dec 26;57(51):6984-6996. doi: 10.1021/acs.biochem.8b01074. Epub 2018 Dec 7.


[The study of psycho-social well being in the educational contexts toward the Va.RP tool: a study case.]

Aiello A, Nardella C.

G Ital Med Lav Ergon. 2018 Jun;40(2):83-89. Italian.


Editorial: Precision Medicine in Oncology.

Re A, Nardella C, Quattrone A, Lunardi A.

Front Oncol. 2018 Oct 26;8:479. doi: 10.3389/fonc.2018.00479. eCollection 2018. No abstract available.


The MocR-like transcription factors: pyridoxal 5'-phosphate-dependent regulators of bacterial metabolism.

Tramonti A, Nardella C, di Salvo ML, Pascarella S, Contestabile R.

FEBS J. 2018 Nov;285(21):3925-3944. doi: 10.1111/febs.14599. Epub 2018 Jul 5. Review.


Management of Patients with Graves' Disease and Orbital Involvement: Role of Spectral Domain Optical Coherence Tomography.

Bruscolini A, La Cava M, Gharbiya M, Sacchetti M, Restivo L, Nardella C, Marenco M, Lambiase A.

J Immunol Res. 2018 Feb 18;2018:1454616. doi: 10.1155/2018/1454616. eCollection 2018.


Salmonella typhimurium PtsJ is a novel MocR-like transcriptional repressor involved in regulating the vitamin B6 salvage pathway.

Tramonti A, Milano T, Nardella C, di Salvo ML, Pascarella S, Contestabile R.

FEBS J. 2017 Feb;284(3):466-484. doi: 10.1111/febs.13994. Epub 2017 Jan 9.


Congenital Corneal Anesthesia and Neurotrophic Keratitis: Diagnosis and Management.

Mantelli F, Nardella C, Tiberi E, Sacchetti M, Bruscolini A, Lambiase A.

Biomed Res Int. 2015;2015:805876. doi: 10.1155/2015/805876. Epub 2015 Sep 16. Review.


Vogt-Koyanagi-Harada disease after stapedotomy.

Accorinti M, Gilardi M, Nardella C, Amorelli GM, Pesci FR.

Eur J Ophthalmol. 2015 Oct 21;25(6):e127-30. doi: 10.5301/ejo.5000625.


Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis.

Lunardi A, Varmeh S, Chen M, Taulli R, Guarnerio J, Ala U, Seitzer N, Ishikawa T, Carver BS, Hobbs RM, Quarantotti V, Ng C, Berger AH, Nardella C, Poliseno L, Montironi R, Castillo-Martin M, Cordon-Cardo C, Signoretti S, Pandolfi PP.

Cancer Discov. 2015 May;5(5):550-63. doi: 10.1158/2159-8290.CD-13-1050. Epub 2015 Feb 4.


Cytomegalovirus anterior uveitis: long-term follow-up of immunocompetent patients.

Accorinti M, Gilardi M, Pirraglia MP, Amorelli GM, Nardella C, Abicca I, Pesci FR.

Graefes Arch Clin Exp Ophthalmol. 2014 Nov;252(11):1817-24. doi: 10.1007/s00417-014-2782-4. Epub 2014 Aug 20. Erratum in: Graefes Arch Clin Exp Ophthalmol. 2014 Dec;252(12):2029.


Vulnerabilities of PTEN-TP53-deficient prostate cancers to compound PARP-PI3K inhibition.

González-Billalabeitia E, Seitzer N, Song SJ, Song MS, Patnaik A, Liu XS, Epping MT, Papa A, Hobbs RM, Chen M, Lunardi A, Ng C, Webster KA, Signoretti S, Loda M, Asara JM, Nardella C, Clohessy JG, Cantley LC, Pandolfi PP.

Cancer Discov. 2014 Aug;4(8):896-904. doi: 10.1158/2159-8290.CD-13-0230. Epub 2014 May 27.


Of model pets and cancer models: an introduction to mouse models of cancer.

Lunardi A, Nardella C, Clohessy JG, Pandolfi PP.

Cold Spring Harb Protoc. 2014 Jan 1;2014(1):17-31. doi: 10.1101/pdb.top069757.


MUC1 is a potential target for the treatment of acute myeloid leukemia stem cells.

Stroopinsky D, Rosenblatt J, Ito K, Mills H, Yin L, Rajabi H, Vasir B, Kufe T, Luptakova K, Arnason J, Nardella C, Levine JD, Joyce RM, Galinsky I, Reiter Y, Stone RM, Pandolfi PP, Kufe D, Avigan D.

Cancer Res. 2013 Sep 1;73(17):5569-79. doi: 10.1158/0008-5472.CAN-13-0677. Epub 2013 Jul 18.


Uveitis heralding previously unknown luetic and HIV infection. Syphilitic uveitis in an Italian referral center.

Restivo L, Abbouda A, Nardella C, Bruscolini A, Pirraglia MP, Pivetti Pezzi P.

Ann Ist Super Sanita. 2013;49(2):133-7. doi: 10.4415/ANN_13_02_04.


Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion.

Wang G, Lunardi A, Zhang J, Chen Z, Ala U, Webster KA, Tay Y, Gonzalez-Billalabeitia E, Egia A, Shaffer DR, Carver B, Liu XS, Taulli R, Kuo WP, Nardella C, Signoretti S, Cordon-Cardo C, Gerald WL, Pandolfi PP.

Nat Genet. 2013 Jul;45(7):739-746. doi: 10.1038/ng.2654. Epub 2013 Jun 2.


A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer.

Lunardi A, Ala U, Epping MT, Salmena L, Clohessy JG, Webster KA, Wang G, Mazzucchelli R, Bianconi M, Stack EC, Lis R, Patnaik A, Cantley LC, Bubley G, Cordon-Cardo C, Gerald WL, Montironi R, Signoretti S, Loda M, Nardella C, Pandolfi PP.

Nat Genet. 2013 Jul;45(7):747-55. doi: 10.1038/ng.2650. Epub 2013 Jun 2.


Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer.

Juvekar A, Burga LN, Hu H, Lunsford EP, Ibrahim YH, Balmañà J, Rajendran A, Papa A, Spencer K, Lyssiotis CA, Nardella C, Pandolfi PP, Baselga J, Scully R, Asara JM, Cantley LC, Wulf GM.

Cancer Discov. 2012 Nov;2(11):1048-63. doi: 10.1158/2159-8290.CD-11-0336. Epub 2012 Aug 22.


Effects of intravitreal bevacizumab on inflammatory choroidal neovascular membrane.

Iannetti L, Paroli MP, Fabiani C, Nardella C, Campanella M, Pivetti-Pezzi P.

Eur J Ophthalmol. 2013 Jan 21;23(1):114 - 118. doi: 10.5301/ejo.5000192. Epub 2012 Aug 8.


Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence.

Scaglioni PP, Rabellino A, Yung TM, Bernardi R, Choi S, Konstantinidou G, Nardella C, Cheng K, Pandolfi PP.

EMBO Mol Med. 2012 Jul;4(7):594-602. doi: 10.1002/emmm.201200233. Epub 2012 Mar 21.


The APL paradigm and the "co-clinical trial" project.

Nardella C, Lunardi A, Patnaik A, Cantley LC, Pandolfi PP.

Cancer Discov. 2011 Jul;1(2):108-16. doi: 10.1158/2159-8290.CD-11-0061. Review.


[The assessment of work-related stress in micro and small enterprises: a validation study of the instrument "CSL" (checklist on job-related stress)].

Nardella C, Deitinger P, Aiello A.

G Ital Med Lav Ergon. 2011 Jul-Sep;33(3 Suppl B):B69-77. Italian.


Life styles, anxiety, expertise: the perception of risk from electromagnetic fields.

Deitinger P, Nardella C, Ronchetti M, Bonafede M, Grandi C.

G Ital Med Lav Ergon. 2011 Jul-Sep;33(3 Suppl B):B14-20.


Pro-senescence therapy for cancer treatment.

Nardella C, Clohessy JG, Alimonti A, Pandolfi PP.

Nat Rev Cancer. 2011 Jun 24;11(7):503-11. doi: 10.1038/nrc3057. Review.


Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis.

Nardella C, Lunardi A, Fedele G, Clohessy JG, Alimonti A, Kozma SC, Thomas G, Loda M, Pandolfi PP.

Cancer Res. 2011 May 15;71(10):3669-75. doi: 10.1158/0008-5472.CAN-10-3962. Epub 2011 Mar 28.


Faithfull modeling of PTEN loss driven diseases in the mouse.

Nardella C, Carracedo A, Salmena L, Pandolfi PP.

Curr Top Microbiol Immunol. 2010;347:135-68. doi: 10.1007/82_2010_62. Review.


[Assessment of occupational stress among shopping centre employees].

Fenga C, Di Nola C, Maviglia P, Cacciola A, Nardella C.

G Ital Med Lav Ergon. 2009 Jul-Sep;31(3 Suppl B):B56-63. Italian.


Subtle variations in Pten dose determine cancer susceptibility.

Alimonti A, Carracedo A, Clohessy JG, Trotman LC, Nardella C, Egia A, Salmena L, Sampieri K, Haveman WJ, Brogi E, Richardson AL, Zhang J, Pandolfi PP.

Nat Genet. 2010 May;42(5):454-8. doi: 10.1038/ng.556. Epub 2010 Apr 18.


Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence.

Lin HK, Chen Z, Wang G, Nardella C, Lee SW, Chan CH, Yang WL, Wang J, Egia A, Nakayama KI, Cordon-Cardo C, Teruya-Feldstein J, Pandolfi PP.

Nature. 2010 Mar 18;464(7287):374-9. doi: 10.1038/nature08815. Erratum in: Nature. 2010 Jul 15;466(7304):398. Chan, Chan-Hsin [corrected to Chan, Chia-Hsin].


A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis.

Alimonti A, Nardella C, Chen Z, Clohessy JG, Carracedo A, Trotman LC, Cheng K, Varmeh S, Kozma SC, Thomas G, Rosivatz E, Woscholski R, Cognetti F, Scher HI, Pandolfi PP.

J Clin Invest. 2010 Mar;120(3):681-93. doi: 10.1172/JCI40535. Epub 2010 Feb 8.


[Italian D.Law 81/2008: confirmation and news in the subject of work-related stress].

Deitinger P, Nardella C, Bentivenga R, Ghelli M, Persechino B, Iavicoli S.

G Ital Med Lav Ergon. 2009 Apr-Jun;31(2):154-62. Review. Italian.


Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.

Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP.

Nat Genet. 2009 May;41(5):619-24. doi: 10.1038/ng.370. Epub 2009 Apr 26.


ETS rearrangements and prostate cancer initiation.

Carver BS, Tran J, Chen Z, Carracedo-Perez A, Alimonti A, Nardella C, Gopalan A, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP.

Nature. 2009 Feb 12;457(7231):E1; discussion E2-3. doi: 10.1038/nature07738.


Differential requirement of mTOR in postmitotic tissues and tumorigenesis.

Nardella C, Carracedo A, Alimonti A, Hobbs RM, Clohessy JG, Chen Z, Egia A, Fornari A, Fiorentino M, Loda M, Kozma SC, Thomas G, Cordon-Cardo C, Pandolfi PP.

Sci Signal. 2009 Jan 27;2(55):ra2. doi: 10.1126/scisignal.2000189.


Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer.

Carracedo A, Ma L, Teruya-Feldstein J, Rojo F, Salmena L, Alimonti A, Egia A, Sasaki AT, Thomas G, Kozma SC, Papa A, Nardella C, Cantley LC, Baselga J, Pandolfi PP.

J Clin Invest. 2008 Sep;118(9):3065-74. doi: 10.1172/JCI34739.


Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events.

Nardella C, Chen Z, Salmena L, Carracedo A, Alimonti A, Egia A, Carver B, Gerald W, Cordon-Cardo C, Pandolfi PP.

Genes Dev. 2008 Aug 15;22(16):2172-7. doi: 10.1101/gad.1699608.


Mechanism of activation of human heparanase investigated by protein engineering.

Nardella C, Lahm A, Pallaoro M, Brunetti M, Vannini A, Steinkühler C.

Biochemistry. 2004 Feb 24;43(7):1862-73.


Characterization of the hepatitis C virus NS2/3 processing reaction by using a purified precursor protein.

Pallaoro M, Lahm A, Biasiol G, Brunetti M, Nardella C, Orsatti L, Bonelli F, Orrù S, Narjes F, Steinkühler C.

J Virol. 2001 Oct;75(20):9939-46.


Choline incorporation into phospholipids in brain areas from spontaneously hypertensive rats: effect of oxiracetam treatment.

Nardella C, Terracina L, Brunetti M, Avellini L, De Medio GE, Gaiti A, Belfiore P, Mariani O.

Farmaco. 1991 Sep;46(9):1051-9.


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