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Items: 28


Dual Inhibition of Klebsiella pneumoniae and Pseudomonas aeruginosa Iron Metabolism Using Gallium Porphyrin and Gallium Nitrate.

Choi SR, Britigan BE, Narayanasamy P.

ACS Infect Dis. 2019 Sep 13;5(9):1559-1569. doi: 10.1021/acsinfecdis.9b00100. Epub 2019 Jul 16.


Knowledge and perceptions of Indian primary care nurses towards mental illness.

Gandhi S, Poreddi V, Govindan R, G J, Anjanappa S, Sahu M, Narayanasamy P, N M, C N, Badamath S.

Invest Educ Enferm. 2019 Feb;37(1). doi: 10.17533/udea.iee.v37n1e06.


Novel MenA Inhibitors Are Bactericidal against Mycobacterium tuberculosis and Synergize with Electron Transport Chain Inhibitors.

Berube BJ, Russell D, Castro L, Choi SR, Narayanasamy P, Parish T.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e02661-18. doi: 10.1128/AAC.02661-18. Print 2019 Jun.


Iron/Heme Metabolism-Targeted Gallium(III) Nanoparticles Are Active against Extracellular and Intracellular Pseudomonas aeruginosa and Acinetobacter baumannii.

Choi SR, Britigan BE, Narayanasamy P.

Antimicrob Agents Chemother. 2019 Mar 27;63(4). pii: e02643-18. doi: 10.1128/AAC.02643-18. Print 2019 Apr.


In Vitro Efficacy of Free and Nanoparticle Formulations of Gallium(III) meso-Tetraphenylporphyrine against Mycobacterium avium and Mycobacterium abscessus and Gallium Biodistribution in Mice.

Choi SR, Britigan BE, Switzer B, Hoke T, Moran D, Narayanasamy P.

Mol Pharm. 2018 Mar 5;15(3):1215-1225. doi: 10.1021/acs.molpharmaceut.7b01036. Epub 2018 Feb 16.


Neuroprotection through flavonoid: Enhancement of the glyoxalase pathway.

Frandsen JR, Narayanasamy P.

Redox Biol. 2018 Apr;14:465-473. doi: 10.1016/j.redox.2017.10.015. Epub 2017 Oct 18. Review.


Flavonoid Enhances the Glyoxalase Pathway in Cerebellar Neurons to Retain Cellular Functions.

Frandsen J, Narayanasamy P.

Sci Rep. 2017 Jul 11;7(1):5126. doi: 10.1038/s41598-017-05287-z.


Gallium nanoparticles facilitate phagosome maturation and inhibit growth of virulent Mycobacterium tuberculosis in macrophages.

Choi SR, Britigan BE, Moran DM, Narayanasamy P.

PLoS One. 2017 May 18;12(5):e0177987. doi: 10.1371/journal.pone.0177987. eCollection 2017.


Ga(III) Nanoparticles Inhibit Growth of both Mycobacterium tuberculosis and HIV and Release of Interleukin-6 (IL-6) and IL-8 in Coinfected Macrophages.

Choi SR, Britigan BE, Narayanasamy P.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02505-16. doi: 10.1128/AAC.02505-16. Print 2017 Apr.


Development of potential broad spectrum antimicrobials using C2-symmetric 9-fluorenone alkyl amine.

Choi SR, Larson MA, Hinrichs SH, Narayanasamy P.

Bioorg Med Chem Lett. 2016 Apr 15;26(8):1997-9. doi: 10.1016/j.bmcl.2016.02.087. Epub 2016 Mar 2.


Genome-wide transcriptomic and proteomic analyses of bollworm-infested developing cotton bolls revealed the genes and pathways involved in the insect pest defence mechanism.

Kumar S, Kanakachari M, Gurusamy D, Kumar K, Narayanasamy P, Kethireddy Venkata P, Solanke A, Gamanagatti S, Hiremath V, Katageri IS, Leelavathi S, Kumar PA, Reddy VS.

Plant Biotechnol J. 2016 Jun;14(6):1438-55. doi: 10.1111/pbi.12508. Epub 2016 Jan 22.


Discovery of bicyclic inhibitors against menaquinone biosynthesis.

Choi SR, Larson MA, Hinrichs SH, Bartling AM, Frandsen J, Narayanasamy P.

Future Med Chem. 2016 Jan;8(1):11-6. doi: 10.4155/fmc.15.168.


Potential of N-acetylated-para-aminosalicylic acid to accelerate manganese enhancement decline for long-term MEMRI in rodent brain.

Bade AN, Zhou B, McMillan J, Narayanasamy P, Veerubhotla R, Gendelman HE, Boska MD, Liu Y.

J Neurosci Methods. 2015 Aug 15;251:92-8. doi: 10.1016/j.jneumeth.2015.05.013. Epub 2015 May 22.


Long-acting antituberculous therapeutic nanoparticles target macrophage endosomes.

Edagwa BJ, Guo D, Puligujja P, Chen H, McMillan J, Liu X, Gendelman HE, Narayanasamy P.

FASEB J. 2014 Dec;28(12):5071-82. doi: 10.1096/fj.14-255786. Epub 2014 Aug 13. Erratum in: FASEB J. 2017 Mar;31(3):1248.


Synthesis of azide derivative and discovery of glyoxalase pathway inhibitor against pathogenic bacteria.

Edagwa B, Wang Y, Narayanasamy P.

Bioorg Med Chem Lett. 2013 Nov 15;23(22):6138-40. doi: 10.1016/j.bmcl.2013.09.011. Epub 2013 Sep 10.


Combinatorial assessments of brain tissue metabolomics and histopathology in rodent models of human immunodeficiency virus infection.

Epstein AA, Narayanasamy P, Dash PK, High R, Bathena SP, Gorantla S, Poluektova LY, Alnouti Y, Gendelman HE, Boska MD.

J Neuroimmune Pharmacol. 2013 Dec;8(5):1224-38. doi: 10.1007/s11481-013-9461-9. Epub 2013 May 24.


Biochemical and biologic characterization of exosomes and microvesicles as facilitators of HIV-1 infection in macrophages.

Kadiu I, Narayanasamy P, Dash PK, Zhang W, Gendelman HE.

J Immunol. 2012 Jul 15;189(2):744-54. doi: 10.4049/jimmunol.1102244. Epub 2012 Jun 18.


DosS responds to a reduced electron transport system to induce the Mycobacterium tuberculosis DosR regulon.

Honaker RW, Dhiman RK, Narayanasamy P, Crick DC, Voskuil MI.

J Bacteriol. 2010 Dec;192(24):6447-55. doi: 10.1128/JB.00978-10. Epub 2010 Oct 15.


Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF.

Narayanasamy P, Eoh H, Brennan PJ, Crick DC.

Chem Biol. 2010 Feb 26;17(2):117-22. doi: 10.1016/j.chembiol.2010.01.013.


Expression and characterization of soluble 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase from bacterial pathogens.

Eoh H, Narayanasamy P, Brown AC, Parish T, Brennan PJ, Crick DC.

Chem Biol. 2009 Dec 24;16(12):1230-9. doi: 10.1016/j.chembiol.2009.10.014.



Narayanasamy P, Crick DC.

Heterocycles. 2008 Mar 30;76(1):243-247.


Menaquinone synthesis is critical for maintaining mycobacterial viability during exponential growth and recovery from non-replicating persistence.

Dhiman RK, Mahapatra S, Slayden RA, Boyne ME, Lenaerts A, Hinshaw JC, Angala SK, Chatterjee D, Biswas K, Narayanasamy P, Kurosu M, Crick DC.

Mol Microbiol. 2009 Apr;72(1):85-97. doi: 10.1111/j.1365-2958.2009.06625.x. Epub 2009 Feb 11.


Chemoenzymatic synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol: A substrate for IspE.

Narayanasamy P, Eoh H, Crick DC.

Tetrahedron Lett. 2008 Jul 21;49(29-30):4461-4463.


Discovery of 1,4-dihydroxy-2-naphthoate [corrected] prenyltransferase inhibitors: new drug leads for multidrug-resistant gram-positive pathogens.

Kurosu M, Narayanasamy P, Biswas K, Dhiman R, Crick DC.

J Med Chem. 2007 Aug 23;50(17):3973-5. Epub 2007 Jul 21. Erratum in: J Med Chem. 2007 Oct 4;50(20):5048.

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