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Items: 28

1.

Stereodivergent, Chemoenzymatic Synthesis of Azaphilone Natural Products.

Pyser JB, Baker Dockrey SA, Benítez AR, Joyce LA, Wiscons RA, Smith JL, Narayan ARH.

J Am Chem Soc. 2019 Nov 6. doi: 10.1021/jacs.9b09385. [Epub ahead of print]

PMID:
31692339
2.

"Females Are Not Just 'Protected' Males": Sex-Specific Vulnerabilities in Placenta and Brain after Prenatal Immune Disruption.

Braun AE, Carpentier PA, Babineau BA, Narayan AR, Kielhold ML, Moon HM, Shankar A, Su J, Saravanapandian V, Haditsch U, Palmer TD.

eNeuro. 2019 Nov 7;6(6). pii: ENEURO.0358-19.2019. doi: 10.1523/ENEURO.0358-19.2019. Print 2019 Nov/Dec.

3.

Hydroxyl Radical-Coupled Electron-Transfer Mechanism of Flavin-Dependent Hydroxylases.

Tweedy SE, Rodríguez Benítez A, Narayan ARH, Zimmerman PM, Brooks CL 3rd, Wymore T.

J Phys Chem B. 2019 Sep 26;123(38):8065-8073. doi: 10.1021/acs.jpcb.9b08178. Epub 2019 Sep 18.

PMID:
31532200
4.

Biocatalytic synthesis of α-amino ketones.

Chun SW, Narayan ARH.

Synlett. 2019 Jul;30(11):1269-1274. doi: 10.1055/s-0037-1611755. Epub 2019 Mar 19.

5.

Structural basis for selectivity in flavin-dependent monooxygenase-catalyzed oxidative dearomatization.

Benítez AR, Tweedy S, Baker Dockrey SA, Lukowski AL, Wymore T, Khare D, Brooks CL 3rd, Palfey BA, Smith JL, Narayan ARH.

ACS Catal. 2019 Apr 5;9(4):3633-3640. doi: 10.1021/acscatal.8b04575. Epub 2019 Mar 25.

PMID:
31346489
6.

Flavin-dependent biocatalysts in synthesis.

Baker Dockrey SA, Narayan ARH.

Tetrahedron. 2019 Mar 1;75(9):1115-1121. doi: 10.1016/j.tet.2019.01.008. Epub 2019 Jan 12.

7.

Positioning-Group-Enabled Biocatalytic Oxidative Dearomatization.

Dockrey SAB, Suh CE, Benítez AR, Wymore T, Brooks CL 3rd, Narayan ARH.

ACS Cent Sci. 2019 Jun 26;5(6):1010-1016. doi: 10.1021/acscentsci.9b00163. Epub 2019 Jun 12.

8.

Biocatalytic Detoxification of Paralytic Shellfish Toxins.

Lukowski AL, Denomme N, Hinze ME, Hall S, Isom LL, Narayan ARH.

ACS Chem Biol. 2019 May 17;14(5):941-948. doi: 10.1021/acschembio.9b00123. Epub 2019 Apr 15.

9.

Charting a course for chemistry.

Aspuru-Guzik A, Baik MH, Balasubramanian S, Banerjee R, Bart S, Borduas-Dedekind N, Chang S, Chen P, Corminboeuf C, Coudert FX, Cronin L, Crudden C, Cuk T, Doyle AG, Fan C, Feng X, Freedman D, Furukawa S, Ghosh S, Glorius F, Jeffries-El M, Katsonis N, Li A, Linse SS, Marchesan S, Maulide N, Milo A, Narayan ARH, Naumov P, Nevado C, Nyokong T, Palacin R, Reid M, Robinson C, Robinson G, Sarpong R, Schindler C, Schlau-Cohen GS, Schmidt TW, Sessoli R, Shao-Horn Y, Sleiman H, Sutherland J, Taylor A, Tezcan A, Tortosa M, Walsh A, Watson AJB, Weckhuysen BM, Weiss E, Wilson D, Yam VW, Yang X, Ying JY, Yoon T, You SL, Zarbin AJG, Zhang H.

Nat Chem. 2019 Apr;11(4):286-294. doi: 10.1038/s41557-019-0236-7. No abstract available.

PMID:
30903035
10.

Natural Voltage-Gated Sodium Channel Ligands: Biosynthesis and Biology.

Lukowski AL, Narayan ARH.

Chembiochem. 2019 May 15;20(10):1231-1241. doi: 10.1002/cbic.201800754. Epub 2019 Mar 27. Review.

PMID:
30605564
11.

Whole-cell biocatalysis platform for gram-scale oxidative dearomatization of phenols.

Baker Dockrey SA, Doyon TJ, Perkins JC, Narayan ARH.

Chem Biol Drug Des. 2019 Jun;93(6):1207-1213. doi: 10.1111/cbdd.13443. Epub 2018 Nov 28.

PMID:
30485666
12.

C-H Hydroxylation in Paralytic Shellfish Toxin Biosynthesis.

Lukowski AL, Ellinwood DC, Hinze ME, DeLuca RJ, Du Bois J, Hall S, Narayan ARH.

J Am Chem Soc. 2018 Sep 19;140(37):11863-11869. doi: 10.1021/jacs.8b08901. Epub 2018 Sep 7.

13.

Chemistry of a Unique Polyketide-like Synthase.

Chun SW, Hinze ME, Skiba MA, Narayan ARH.

J Am Chem Soc. 2018 Feb 21;140(7):2430-2433. doi: 10.1021/jacs.7b13297. Epub 2018 Feb 8.

14.

Biocatalytic site- and enantioselective oxidative dearomatization of phenols.

Baker Dockrey SA, Lukowski AL, Becker MR, Narayan ARH.

Nat Chem. 2018 Feb;10(2):119-125. doi: 10.1038/nchem.2879. Epub 2017 Nov 13.

15.

Synthesis of Diverse 11- and 12-Membered Macrolactones from a Common Linear Substrate Using a Single Biocatalyst.

Gilbert MM, DeMars MD 2nd, Yang S, Grandner JM, Wang S, Wang H, Narayan ARH, Sherman DH, Houk KN, Montgomery J.

ACS Cent Sci. 2017 Dec 27;3(12):1304-1310. doi: 10.1021/acscentsci.7b00450. Epub 2017 Nov 15.

16.

High voltage electrical shock with multiple life-threatening injuries.

Kumar SS, Narayan AR, Gopal S, Kumar JG, Agrawal A.

Int J Crit Illn Inj Sci. 2015 Oct-Dec;5(4):266-8. doi: 10.4103/2229-5151.170847. No abstract available.

17.

Enzymatic hydroxylation of an unactivated methylene C-H bond guided by molecular dynamics simulations.

Narayan AR, Jiménez-Osés G, Liu P, Negretti S, Zhao W, Gilbert MM, Ramabhadran RO, Yang YF, Furan LR, Li Z, Podust LM, Montgomery J, Houk KN, Sherman DH.

Nat Chem. 2015 Aug;7(8):653-60. doi: 10.1038/nchem.2285. Epub 2015 Jun 29.

18.

Dysregulation of astrocyte extracellular signaling in Costello syndrome.

Krencik R, Hokanson KC, Narayan AR, Dvornik J, Rooney GE, Rauen KA, Weiss LA, Rowitch DH, Ullian EM.

Sci Transl Med. 2015 May 6;7(286):286ra66. doi: 10.1126/scitranslmed.aaa5645.

19.

Structural rearrangements of a polyketide synthase module during its catalytic cycle.

Whicher JR, Dutta S, Hansen DA, Hale WA, Chemler JA, Dosey AM, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G.

Nature. 2014 Jun 26;510(7506):560-4. doi: 10.1038/nature13409. Epub 2014 Jun 18.

20.

Structure of a modular polyketide synthase.

Dutta S, Whicher JR, Hansen DA, Hale WA, Chemler JA, Congdon GR, Narayan AR, Håkansson K, Sherman DH, Smith JL, Skiniotis G.

Nature. 2014 Jun 26;510(7506):512-7. doi: 10.1038/nature13423. Epub 2014 Jun 18.

21.

Directing group-controlled regioselectivity in an enzymatic C-H bond oxygenation.

Negretti S, Narayan AR, Chiou KC, Kells PM, Stachowski JL, Hansen DA, Podust LM, Montgomery J, Sherman DH.

J Am Chem Soc. 2014 Apr 2;136(13):4901-4. doi: 10.1021/ja5016052. Epub 2014 Mar 21.

22.

Protic-solvent-mediated cycloisomerization of quinoline and isoquinoline propargylic alcohols: syntheses of (±)-3-demethoxyerythratidinone and (±)-cocculidine.

Heller ST, Kiho T, Narayan AR, Sarpong R.

Angew Chem Int Ed Engl. 2013 Oct 11;52(42):11129-33. doi: 10.1002/anie.201304687. Epub 2013 Sep 5.

23.

Biocatalytic synthesis of pikromycin, methymycin, neomethymycin, novamethymycin, and ketomethymycin.

Hansen DA, Rath CM, Eisman EB, Narayan AR, Kittendorf JD, Mortison JD, Yoon YJ, Sherman DH.

J Am Chem Soc. 2013 Jul 31;135(30):11232-8. doi: 10.1021/ja404134f. Epub 2013 Jul 18.

24.

mTOR activation is required for the anti-alcohol effect of ketamine, but not memantine, in alcohol-preferring rats.

Sabino V, Narayan AR, Zeric T, Steardo L, Cottone P.

Behav Brain Res. 2013 Jun 15;247:9-16. doi: 10.1016/j.bbr.2013.02.030. Epub 2013 Mar 4.

25.

Chemistry. Re-engineering nature's catalysts.

Narayan AR, Sherman DH.

Science. 2013 Jan 18;339(6117):283-4. doi: 10.1126/science.1233324. No abstract available.

PMID:
23329039
26.

The uncompetitive NMDA receptor antagonists ketamine and memantine preferentially increase the choice for a small, immediate reward in low-impulsive rats.

Cottone P, Iemolo A, Narayan AR, Kwak J, Momaney D, Sabino V.

Psychopharmacology (Berl). 2013 Mar;226(1):127-38. doi: 10.1007/s00213-012-2898-3. Epub 2012 Oct 27.

27.

A modified adjusting delay task to assess impulsive choice between isocaloric reinforcers in non-deprived male rats: effects of 5-HT₂A/C and 5-HT₁A receptor agonists.

Blasio A, Narayan AR, Kaminski BJ, Steardo L, Sabino V, Cottone P.

Psychopharmacology (Berl). 2012 Jan;219(2):377-86. doi: 10.1007/s00213-011-2517-8. Epub 2011 Oct 12.

28.

Toxic epidermal necrolysis in systemic lupus erythematosus.

Horne NS, Narayan AR, Young RM, Frieri M.

Autoimmun Rev. 2006 Feb;5(2):160-4. Epub 2005 Nov 2. Review.

PMID:
16431352

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