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Items: 1 to 50 of 339

1.

Blockade of the KATP channel Kir6.2 by memantine represents a novel mechanism relevant to Alzheimer's disease therapy.

Moriguchi S, Ishizuka T, Yabuki Y, Shioda N, Sasaki Y, Tagashira H, Yawo H, Yeh JZ, Sakagami H, Narahashi T, Fukunaga K.

Mol Psychiatry. 2018 Feb;23(2):211-221. doi: 10.1038/mp.2016.187. Epub 2016 Oct 25.

PMID:
27777420
2.

CaMKII activity is essential for improvement of memory-related behaviors by chronic rivastigmine treatment.

Moriguchi S, Tagashira H, Sasaki Y, Yeh JZ, Sakagami H, Narahashi T, Fukunaga K.

J Neurochem. 2014 Mar;128(6):927-37. doi: 10.1111/jnc.12510. Epub 2013 Nov 17.

3.

Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor.

Moriguchi S, Tanaka T, Narahashi T, Fukunaga K.

Hippocampus. 2013 Oct;23(10):942-51. doi: 10.1002/hipo.22150. Epub 2013 Jul 16.

PMID:
23733502
4.

Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation in olfactory bulbectomized mice.

Moriguchi S, Tanaka T, Tagashira H, Narahashi T, Fukunaga K.

Behav Brain Res. 2013 Apr 1;242:150-7. doi: 10.1016/j.bbr.2012.12.054. Epub 2013 Jan 4.

PMID:
23295391
5.

Effects of general anesthetics on P2X4 receptors in a mouse microglial cell line.

Hasaka M, Mori T, Matsuura T, Narahashi T, Kuno M, Asada A, Nishikawa K.

Neuroreport. 2012 Jul 11;23(10):601-5. doi: 10.1097/WNR.0b013e32835509db.

PMID:
22664778
6.

Inhibition of voltage-gated proton channels by local anaesthetics in GMI-R1 rat microglia.

Matsuura T, Mori T, Hasaka M, Kuno M, Kawawaki J, Nishikawa K, Narahashi T, Sawada M, Asada A.

J Physiol. 2012 Feb 15;590(4):827-44. doi: 10.1113/jphysiol.2011.218149. Epub 2011 Dec 19.

7.

Antidepressants inhibit proton currents and tumor necrosis factor-α production in BV2 microglial cells.

Song JH, Marszalec W, Kai L, Yeh JZ, Narahashi T.

Brain Res. 2012 Jan 30;1435:15-23. doi: 10.1016/j.brainres.2011.11.041. Epub 2011 Dec 1.

PMID:
22177663
8.

Glutamate-activated chloride channels: Unique fipronil targets present in insects but not in mammals.

Narahashi T, Zhao X, Ikeda T, Salgado VL, Yeh JZ.

Pestic Biochem Physiol. 2010 Jun 1;97(2):149-152.

9.

Nefiracetam activation of CaM kinase II and protein kinase C mediated by NMDA and metabotropic glutamate receptors in olfactory bulbectomized mice.

Moriguchi S, Han F, Shioda N, Yamamoto Y, Nakajima T, Nakagawasai O, Tadano T, Yeh JZ, Narahashi T, Fukunaga K.

J Neurochem. 2009 Jul;110(1):170-81. doi: 10.1111/j.1471-4159.2009.06122.x. Epub 2009 Apr 27.

10.

Synaptic and behavioral interactions of oseltamivir (Tamiflu) with neurostimulants.

Izumi Y, Tokuda K, O'Dell K, Zorumski C, Narahashi T.

Hum Exp Toxicol. 2008 Dec;27(12):911-7. doi: 10.1177/0960327109102367.

11.

Nefiracetam and galantamine modulation of excitatory and inhibitory synaptic transmission via stimulation of neuronal nicotinic acetylcholine receptors in rat cortical neurons.

Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Fukunaga K, Narahashi T.

Neuroscience. 2009 May 5;160(2):484-91. doi: 10.1016/j.neuroscience.2009.02.055. Epub 2009 Mar 9.

PMID:
19272425
12.

Galantamine enhancement of long-term potentiation is mediated by calcium/calmodulin-dependent protein kinase II and protein kinase C activation.

Moriguchi S, Shioda N, Han F, Yeh JZ, Narahashi T, Fukunaga K.

Hippocampus. 2009 Sep;19(9):844-54. doi: 10.1002/hipo.20572.

PMID:
19253410
13.

Tetrodotoxin: a brief history.

Narahashi T.

Proc Jpn Acad Ser B Phys Biol Sci. 2008;84(5):147-54. Review.

14.

[Prevention of phlebitis caused by vinorelbine chemotherapy in outpatients with breast cancer].

Yokota Y, Suzuki T, Narahashi T, Takizawa J, Kojima M, Shimada R.

Gan To Kagaku Ryoho. 2008 Sep;35(9):1525-9. Japanese.

PMID:
18799905
15.

Use of non-mammalian alternative models for neurotoxicological study.

Peterson RT, Nass R, Boyd WA, Freedman JH, Dong K, Narahashi T.

Neurotoxicology. 2008 May;29(3):546-55. doi: 10.1016/j.neuro.2008.04.006. Epub 2008 Apr 25. Review.

16.

CaM kinase II and protein kinase C activations mediate enhancement of long-term potentiation by nefiracetam in the rat hippocampal CA1 region.

Moriguchi S, Shioda N, Han F, Narahashi T, Fukunaga K.

J Neurochem. 2008 Aug;106(3):1092-103. doi: 10.1111/j.1471-4159.2008.05440.x. Epub 2008 Apr 28.

17.
18.

Neuroexcitatory actions of Tamiflu and its carboxylate metabolite.

Izumi Y, Tokuda K, O'dell KA, Zorumski CF, Narahashi T.

Neurosci Lett. 2007 Oct 9;426(1):54-8. Epub 2007 Sep 1.

19.

Differential actions of insecticides on target sites: basis for selective toxicity.

Narahashi T, Zhao X, Ikeda T, Nagata K, Yeh JZ.

Hum Exp Toxicol. 2007 Apr;26(4):361-6. Review.

20.

Inhibition of inward rectifier K+ currents by angiotensin II in rat atrial myocytes: lack of effects in cells from spontaneously hypertensive rats.

Sonoyama K, Ninomiya H, Igawa O, Kaetsu Y, Furuse Y, Hamada T, Miake J, Li P, Yamamoto Y, Ogino K, Yoshida A, Taniguchi S, Kurata Y, Matsuoka S, Narahashi T, Shiota G, Nozawa Y, Matsubara H, Horiuchi M, Shirayoshi Y, Hisatome I.

Hypertens Res. 2006 Nov;29(11):923-34.

PMID:
17345793
21.

Effects of ethanol on excitatory and inhibitory synaptic transmission in rat cortical neurons.

Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Narahashi T.

Alcohol Clin Exp Res. 2007 Jan;31(1):89-99. Erratum in: Alcohol Clin Exp Res. 2007 Mar;31(3):preceding 356.

PMID:
17207106
22.

Nefiracetam potentiates N-methyl-D-aspartate (NMDA) receptor function via protein kinase C activation and reduces magnesium block of NMDA receptor.

Moriguchi S, Shioda N, Maejima H, Zhao X, Marszalec W, Yeh JZ, Fukunaga K, Narahashi T.

Mol Pharmacol. 2007 Feb;71(2):580-7. Epub 2006 Nov 9.

PMID:
17095583
23.

In vitro galantamine-memantine co-application: mechanism of beneficial action.

Zhao X, Marszalec W, Toth PT, Huang J, Yeh JZ, Narahashi T.

Neuropharmacology. 2006 Dec;51(7-8):1181-91. Epub 2006 Sep 29.

PMID:
17011596
24.

Cytoplasmic localization of p63 is associated with poor patient survival in lung adenocarcinoma.

Narahashi T, Niki T, Wang T, Goto A, Matsubara D, Funata N, Fukayama M.

Histopathology. 2006 Oct;49(4):349-57.

PMID:
16978197
25.

Effects of ethanol on tonic GABA currents in cerebellar granule cells and mammalian cells recombinantly expressing GABA(A) receptors.

Yamashita M, Marszalec W, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2006 Oct;319(1):431-8. Epub 2006 Jul 14.

PMID:
16844844
26.

Bead-like passage of chloride ions through ClC chloride channels.

Suenaga A, Yeh JZ, Taiji M, Toyama A, Takeuchi H, Son M, Takayama K, Iwamoto M, Sato I, Narahashi T, Konagaya A, Goto K.

Biophys Chem. 2006 Mar 1;120(1):36-43. Epub 2005 Nov 9.

PMID:
16288955
27.

Effects of angiotensin II on the action potential durations of atrial myocytes in hypertensive rats.

Sonoyama K, Igawa O, Miake J, Yamamoto Y, Sugihara S, Sasaki N, Shimoyama M, Hamada T, Taniguchi S, Yoshida A, Ogino K, Shigemasa C, Hoshikawa Y, Kurata Y, Shiota G, Narahashi T, Horiuchi M, Matsubara H, Ninomiya H, Hisatome I.

Hypertens Res. 2005 Feb;28(2):173-9.

PMID:
16025745
28.

Modulation of N-methyl-D-aspartate receptors by donepezil in rat cortical neurons.

Moriguchi S, Zhao X, Marszalec W, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2005 Oct;315(1):125-35. Epub 2005 Jun 10.

PMID:
15951396
29.

Block of two subtypes of sodium channels in cockroach neurons by indoxacarb insecticides.

Zhao X, Ikeda T, Salgado VL, Yeh JZ, Narahashi T.

Neurotoxicology. 2005 Jun;26(3):455-65. Epub 2005 Apr 26.

PMID:
15935215
30.

Desensitization of nicotine acetylcholine receptors: modulation by kinase activation and phosphatase inhibition.

Marszalec W, Yeh JZ, Narahashi T.

Eur J Pharmacol. 2005 May 9;514(2-3):83-90.

PMID:
15878498
31.

Sulfone metabolite of fipronil blocks gamma-aminobutyric acid- and glutamate-activated chloride channels in mammalian and insect neurons.

Zhao X, Yeh JZ, Salgado VL, Narahashi T.

J Pharmacol Exp Ther. 2005 Jul;314(1):363-73. Epub 2005 Feb 8.

PMID:
15701711
32.

Isoflurane modulation of neuronal nicotinic acetylcholine receptors expressed in human embryonic kidney cells.

Yamashita M, Mori T, Nagata K, Yeh JZ, Narahashi T.

Anesthesiology. 2005 Jan;102(1):76-84.

PMID:
15618790
33.

Octanol modulation of neuronal nicotinic acetylcholine receptor single channels.

Zuo Y, Yeh JZ, Narahashi T.

Alcohol Clin Exp Res. 2004 Nov;28(11):1648-56.

PMID:
15547451
34.

Mechanisms of action of cognitive enhancers on neuroreceptors.

Narahashi T, Moriguchi S, Zhao X, Marszalec W, Yeh JZ.

Biol Pharm Bull. 2004 Nov;27(11):1701-6. Review.

35.
36.

Halothane and propofol modulation of gamma-aminobutyric acidA receptor single-channel currents.

Kitamura A, Sato R, Marszalec W, Yeh JZ, Ogawa R, Narahashi T.

Anesth Analg. 2004 Aug;99(2):409-15, table of contents.

PMID:
15271715
37.

State-dependent blocking actions of azimilide dihydrochlo-ride (NE-10064) on human cardiac Na(+) channels.

Miake J, Kurata Y, Iizuka K, Furuichi H, Manabe K, Sasaki N, Yamamoto Y, Hoshikawa Y, Taniguchi S, Yoshida A, Igawa O, Makita N, Shiota G, Nanba E, Ohgi S, Narahashi T, Hisatome I.

Circ J. 2004 Jul;68(7):703-11.

38.

Single-channel analyses of ethanol modulation of neuronal nicotinic acetylcholine receptors.

Zuo Y, Nagata K, Yeh JZ, Narahashi T.

Alcohol Clin Exp Res. 2004 May;28(5):688-96.

PMID:
15166642
39.

Fipronil modulation of GABAA receptor single-channel currents.

Ikeda T, Nagata K, Kono Y, Yeh JZ, Narahashi T.

Pest Manag Sci. 2004 May;60(5):487-92.

PMID:
15154517
40.

Mechanism of action of galantamine on N-methyl-D-aspartate receptors in rat cortical neurons.

Moriguchi S, Marszalec W, Zhao X, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2004 Sep;310(3):933-42. Epub 2004 Apr 30.

PMID:
15121761
41.

Fipronil is a potent open channel blocker of glutamate-activated chloride channels in cockroach neurons.

Zhao X, Yeh JZ, Salgado VL, Narahashi T.

J Pharmacol Exp Ther. 2004 Jul;310(1):192-201. Epub 2004 Mar 10.

PMID:
15014137
42.

Ca2+ binding sites in calmodulin and troponin C alter interhelical angle movements.

Goto K, Toyama A, Takeuchi H, Takayama K, Saito T, Iwamoto M, Yeh JZ, Narahashi T.

FEBS Lett. 2004 Mar 12;561(1-3):51-7.

43.

Fipronil modulation of glutamate-induced chloride currents in cockroach thoracic ganglion neurons.

Ikeda T, Zhao X, Kono Y, Yeh JZ, Narahashi T.

Neurotoxicology. 2003 Dec;24(6):807-15.

PMID:
14637375
44.

Unique mechanism of action of Alzheimer's drugs on brain nicotinic acetylcholine receptors and NMDA receptors.

Narahashi T, Marszalec W, Moriguchi S, Yeh JZ, Zhao X.

Life Sci. 2003 Dec 5;74(2-3):281-91.

PMID:
14607256
45.

Principles of electrophysiology: an overview.

Narahashi T.

Curr Protoc Toxicol. 2003 Nov;Chapter 11:Unit11.10. doi: 10.1002/0471140856.tx1110s17. Review.

PMID:
23045088
46.

Potentiation of N-methyl-D-aspartate-induced currents by the nootropic drug nefiracetam in rat cortical neurons.

Moriguchi S, Marszalec W, Zhao X, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2003 Oct;307(1):160-7. Epub 2003 Jun 12.

PMID:
12805478
47.

Differential actions of fipronil and dieldrin insecticides on GABA-gated chloride channels in cockroach neurons.

Zhao X, Salgado VL, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2003 Sep;306(3):914-24. Epub 2003 May 23.

PMID:
12766256
48.

Dual action of n-butanol on neuronal nicotinic alpha4beta2 acetylcholine receptors.

Zuo Y, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2003 Mar;304(3):1143-52.

PMID:
12604691
49.
50.

Effects of halothane and propofol on excitatory and inhibitory synaptic transmission in rat cortical neurons.

Kitamura A, Marszalec W, Yeh JZ, Narahashi T.

J Pharmacol Exp Ther. 2003 Jan;304(1):162-71.

PMID:
12490587

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