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Clinical Practice Use of Liquid Biopsy to Identify RAS/BRAF Mutations in Patients with Metastatic Colorectal Cancer (mCRC): A Single Institution Experience.

Vitiello PP, De Falco V, Giunta EF, Ciardiello D, Cardone C, Vitale P, Zanaletti N, Borrelli C, Poliero L, Terminiello M, Arrichiello G, Caputo V, Famiglietti V, Mattera Iacono V, Marrone F, Di Liello A, Martini G, Napolitano S, Caraglia M, Lombardi A, Franco R, De Vita F, Morgillo F, Troiani T, Ciardiello F, Martinelli E.

Cancers (Basel). 2019 Oct 8;11(10). pii: E1504. doi: 10.3390/cancers11101504.


Use of narrative medicine to identify key factors for effective doctor-patient relationships in severe asthma.

Cappuccio A, Napolitano S, Menzella F, Pellegrini G, Policreti A, Pelaia G, Porpiglia PA, Marini MG; SOUND GROUP.

Multidiscip Respir Med. 2019 Sep 2;14:26. doi: 10.1186/s40248-019-0190-7. eCollection 2019.


Solution filtering affects the glassy dynamics of spincoated thin films of poly(4-chlorostyrene).

Debot A, Tripathi P, Napolitano S.

Eur Phys J E Soft Matter. 2019 Aug 13;42(8):102. doi: 10.1140/epje/i2019-11865-0.


Ruminative responses to interpersonal precipitants mediate borderline personality disorder features' effects on distress reactivity and recovery in daily life.

Yaroslavsky I, Napolitano SC, France CM.

J Clin Psychol. 2019 Aug 8. doi: 10.1002/jclp.22839. [Epub ahead of print]


Functional analyses of ancestral thioredoxins provide insights into their evolutionary history.

Napolitano S, Reber RJ, Rubini M, Glockshuber R.

J Biol Chem. 2019 Sep 20;294(38):14105-14118. doi: 10.1074/jbc.RA119.009718. Epub 2019 Jul 31.


Acceptance and Commitment Therapy to Increase Adherence to Penile Injection Therapy-Based Rehabilitation After Radical Prostatectomy: Pilot Randomized Controlled Trial.

Nelson CJ, Saracino RM, Napolitano S, Pessin H, Narus JB, Mulhall JP.

J Sex Med. 2019 Sep;16(9):1398-1408. doi: 10.1016/j.jsxm.2019.05.013. Epub 2019 Jul 2.


Mechanisms of Innate and Acquired Resistance to Anti-EGFR therapy: A Review of Current Knowledge with a Focus on Rechallenge Therapies.

Parseghian CM, Napolitano S, Loree JM, Kopetz S.

Clin Cancer Res. 2019 Jul 1. doi: 10.1158/1078-0432.CCR-19-0823. [Epub ahead of print] Review.


Suicide in Patients With Cancer: Identifying the Risk Factors.

McFarland DC, Walsh L, Napolitano S, Morita J, Jaiswal R.

Oncology (Williston Park). 2019 Jun 19;33(6):221-6. Review.


Evolving Strategies for the Management of BRAF-Mutant Metastatic Colorectal Cancer.

Lee HM, Morris V, Napolitano S, Kopetz S.

Oncology (Williston Park). 2019 Jun 19;33(6):206-11. Review.


Combined blockade of MEK and PI3KCA as an effective antitumor strategy in HER2 gene amplified human colorectal cancer models.

Belli V, Matrone N, Napolitano S, Migliardi G, Cottino F, Bertotti A, Trusolino L, Martinelli E, Morgillo F, Ciardiello D, De Falco V, Giunta EF, Bracale U, Ciardiello F, Troiani T.

J Exp Clin Cancer Res. 2019 Jun 4;38(1):236. doi: 10.1186/s13046-019-1230-z.


The inter-rater reliability of the Italian version of Aphasia Rapid Test (ART) for acute ischemic stroke.

Panebianco M, Zavanone C, Dupont S, Perrone P, Pavone A, Napolitano S, Leger A, Samson Y.

Neurol Sci. 2019 Oct;40(10):2171-2174. doi: 10.1007/s10072-019-03931-2. Epub 2019 May 24.


A case report of a severe fluoropyrimidine-related toxicity due to an uncommon DPYD variant.

De Falco V, Natalicchio MI, Napolitano S, Coppola N, Conzo G, Martinelli E, Zanaletti N, Vitale P, Giunta EF, Vietri MT, Vitiello PP, Ciardiello D, Marinaccio A, De Vita F, Ciardiello F, Troiani T.

Medicine (Baltimore). 2019 May;98(21):e15759. doi: 10.1097/MD.0000000000015759.


EPHA2 Is a Predictive Biomarker of Resistance and a Potential Therapeutic Target for Improving Antiepidermal Growth Factor Receptor Therapy in Colorectal Cancer.

Martini G, Cardone C, Vitiello PP, Belli V, Napolitano S, Troiani T, Ciardiello D, Della Corte CM, Morgillo F, Matrone N, Sforza V, Papaccio G, Desiderio V, Paul MC, Moreno-Viedma V, Normanno N, Rachiglio AM, Tirino V, Maiello E, Latiano TP, Rizzi D, Signoriello G, Sibilia M, Ciardiello F, Martinelli E.

Mol Cancer Ther. 2019 Apr;18(4):845-855. doi: 10.1158/1535-7163.MCT-18-0539. Epub 2019 Mar 1.


Receptor tyrosine kinase-dependent PI3K activation is an escape mechanism to vertical suppression of the EGFR/RAS/MAPK pathway in KRAS-mutated human colorectal cancer cell lines.

Vitiello PP, Cardone C, Martini G, Ciardiello D, Belli V, Matrone N, Barra G, Napolitano S, Della Corte C, Turano M, Furia M, Troiani T, Morgillo F, De Vita F, Ciardiello F, Martinelli E.

J Exp Clin Cancer Res. 2019 Jan 28;38(1):41. doi: 10.1186/s13046-019-1035-0.


Anti-EGFR-resistant clones decay exponentially after progression: implications for anti-EGFR re-challenge.

Parseghian CM, Loree JM, Morris VK, Liu X, Clifton KK, Napolitano S, Henry JT, Pereira AA, Vilar E, Johnson B, Kee B, Raghav K, Dasari A, Wu J, Garg N, Raymond VM, Banks KC, Talasaz AA, Lanman RB, Strickler JH, Hong DS, Corcoran RB, Overman MJ, Kopetz S.

Ann Oncol. 2019 Feb 1;30(2):243-249. doi: 10.1093/annonc/mdy509.


Regulation of Gene Expression and Signaling Pathway Activity in Mammalian Cells by Automated Microfluidics Feedback Control.

Postiglione L, Napolitano S, Pedone E, Rocca DL, Aulicino F, Santorelli M, Tumaini B, Marucci L, di Bernardo D.

ACS Synth Biol. 2018 Nov 16;7(11):2558-2565. doi: 10.1021/acssynbio.8b00235. Epub 2018 Oct 22.


Evidence of the clinical utility of a prolonged grief disorder diagnosis.

Lichtenthal WG, Maciejewski PK, Craig Demirjian C, Roberts KE, First MB, Kissane DW, Neimeyer RA, Breitbart W, Slivjak E, Jankauskaite G, Napolitano S, Maercker A, Prigerson HG.

World Psychiatry. 2018 Oct;17(3):364-365. doi: 10.1002/wps.20544. No abstract available.


Eighth American Joint Committee on Cancer (AJCC) melanoma classification: what about stage IIC?

Brancaccio G, Napolitano S, Troiani T, Franco R, Iovino F, Reginelli A, Ciardiello F, Argenziano G.

Br J Dermatol. 2018 Dec;179(6):1422-1423. doi: 10.1111/bjd.17145. Epub 2018 Oct 5. No abstract available.


Is It Personal? Context Moderates BPD Effects on Spontaneous Rumination and Distress.

Napolitano S, Yaroslavsky I, France CM.

J Pers Disord. 2018 Sep 4:1-20. doi: 10.1521/pedi_2018_32_387. [Epub ahead of print]


Clinical and Radiologic Manifestations of Bone Infection in Children with Cat Scratch Disease.

Erdem G, Watson JR, Hunt WG, Young C, Tomatis Souverbielle C, Honegger JR, Cassady KA, Ilgenfritz M, Napolitano S, Koranyi K.

J Pediatr. 2018 Oct;201:274-280.e12. doi: 10.1016/j.jpeds.2018.05.033. Epub 2018 Jul 2.


Taming the Strength of Interfacial Interactions via Nanoconfinement.

Nieto Simavilla D, Huang W, Housmans C, Sferrazza M, Napolitano S.

ACS Cent Sci. 2018 Jun 27;4(6):755-759. doi: 10.1021/acscentsci.8b00240. Epub 2018 Jun 5.


It is finally time for adjuvant therapy in melanoma.

Napolitano S, Brancaccio G, Argenziano G, Martinelli E, Morgillo F, Ciardiello F, Troiani T.

Cancer Treat Rev. 2018 Sep;69:101-111. doi: 10.1016/j.ctrv.2018.06.003. Epub 2018 Jun 9. Review.


Narrative medicine in metastatic prostate cancer reveals ways to improve patient awareness & quality of care.

De Vincentis G, Monari F, Baldari S, Salgarello M, Frantellizzi V, Salvi E, Reale L, Napolitano S, Conti G, Cortesi E.

Future Oncol. 2018 Nov;14(27):2821-2832. doi: 10.2217/fon-2018-0318. Epub 2018 Jun 15.


Recurrent esophageal stricture from previous caustic ingestion treated with 40-year self-dilation: case report and review of literature.

Gambardella C, Allaria A, Siciliano G, Mauriello C, Patrone R, Avenia N, Polistena A, Sanguinetti A, Napolitano S, Conzo G.

BMC Gastroenterol. 2018 May 22;18(1):68. doi: 10.1186/s12876-018-0801-3. Review.


Narrative medicine educational project to improve the care of patients with chronic obstructive pulmonary disease.

Cappuccio A, Sanduzzi Zamparelli A, Verga M, Nardini S, Policreti A, Porpiglia PA, Napolitano S, Marini MG.

ERJ Open Res. 2018 May 4;4(2). pii: 00155-2017. doi: 10.1183/23120541.00155-2017. eCollection 2018 Apr.


Evidence of a Transition Layer between the Free Surface and the Bulk.

Ogieglo W, Tempelman K, Napolitano S, Benes NE.

J Phys Chem Lett. 2018 Mar 15;9(6):1195-1199. doi: 10.1021/acs.jpclett.8b00076. Epub 2018 Feb 23.


Novel In Vitro Cancer Models for Optimizing Anti-EGFR Therapies.

Napolitano S, Ciardiello F.

Clin Cancer Res. 2018 Feb 15;24(4):727-729. doi: 10.1158/1078-0432.CCR-17-2937. Epub 2017 Dec 8.


Clinical outcome and molecular characterisation of chemorefractory metastatic colorectal cancer patients with long-term efficacy of regorafenib treatment.

Martinelli E, Sforza V, Cardone C, Capasso A, Nappi A, Martini G, Napolitano S, Rachiglio AM, Normanno N, Cappabianca S, Reginelli A, Bisceglie MD, Latiano TP, Maiello E, Orditura M, De Vita F, Morgillo F, Ciardiello F, Troiani T.

ESMO Open. 2017 Jul 29;2(3):e000177. doi: 10.1136/esmoopen-2017-000177. eCollection 2017.


Antitumor efficacy of triple monoclonal antibody inhibition of epidermal growth factor receptor (EGFR) with MM151 in EGFR-dependent and in cetuximab-resistant human colorectal cancer cells.

Napolitano S, Martini G, Martinelli E, Della Corte CM, Morgillo F, Belli V, Cardone C, Matrone N, Ciardiello F, Troiani T.

Oncotarget. 2017 Aug 2;8(47):82773-82783. doi: 10.18632/oncotarget.19797. eCollection 2017 Oct 10.


Clinical outcome of patients with chemorefractory metastatic colorectal cancer treated with trifluridine/tipiracil (TAS-102): a single Italian institution compassionate use programme.

Sforza V, Martinelli E, Cardone C, Martini G, Napolitano S, Vitiello PP, Vitale P, Zanaletti N, Reginelli A, Bisceglie MD, Latiano TP, Bochicchio AM, Cecere F, Selvaggi F, Ciardiello F, Troiani T.

ESMO Open. 2017 Sep 21;2(4):e000229. doi: 10.1136/esmoopen-2017-000229. eCollection 2017.


Regorafenib in combination with silybin as a novel potential strategy for the treatment of metastatic colorectal cancer.

Belli V, Sforza V, Cardone C, Martinelli E, Barra G, Matrone N, Napolitano S, Morgillo F, Tuccillo C, Federico A, Dallio M, Loguercio C, Gravina AG, De Palma R, Ciardiello F, Troiani T.

Oncotarget. 2017 Aug 7;8(40):68305-68316. doi: 10.18632/oncotarget.20054. eCollection 2017 Sep 15.


Therapeutic efficacy of SYM004, a mixture of two anti-EGFR antibodies in human colorectal cancer with acquired resistance to cetuximab and MET activation.

Napolitano S, Martini G, Martinelli E, Belli V, Parascandolo A, Laukkanen MO, Sforza V, Morgillo F, Ciardiello D, Ciardiello F, Troiani T.

Oncotarget. 2017 Jun 27;8(40):67592-67604. doi: 10.18632/oncotarget.18749. eCollection 2017 Sep 15.


Irreversible Adsorption Governs the Equilibration of Thin Polymer Films.

Panagopoulou A, Napolitano S.

Phys Rev Lett. 2017 Sep 1;119(9):097801. doi: 10.1103/PhysRevLett.119.097801. Epub 2017 Aug 31.


Pretreatment predictors of malignant evolution in patients with ischemic stroke undergoing mechanical thrombectomy.

Davoli A, Motta C, Koch G, Diomedi M, Napolitano S, Giordano A, Panella M, Morosetti D, Fabiano S, Floris R, Gandini R, Sallustio F.

J Neurointerv Surg. 2018 Apr;10(4):340-344. doi: 10.1136/neurintsurg-2017-013224. Epub 2017 Aug 10.


Present and future of metastatic colorectal cancer treatment: A review of new candidate targets.

Martini G, Troiani T, Cardone C, Vitiello P, Sforza V, Ciardiello D, Napolitano S, Della Corte CM, Morgillo F, Raucci A, Cuomo A, Selvaggi F, Ciardiello F, Martinelli E.

World J Gastroenterol. 2017 Jul 14;23(26):4675-4688. doi: 10.3748/wjg.v23.i26.4675. Review.


Phase II Study of Sequential Infusion of Donor Lymphocyte Infusion and Cytokine-Induced Killer Cells for Patients Relapsed after Allogeneic Hematopoietic Stem Cell Transplantation.

Introna M, Lussana F, Algarotti A, Gotti E, Valgardsdottir R, Micò C, Grassi A, Pavoni C, Ferrari ML, Delaini F, Todisco E, Cavattoni I, Deola S, Biagi E, Balduzzi A, Rovelli A, Parma M, Napolitano S, Sgroi G, Marrocco E, Perseghin P, Belotti D, Cabiati B, Gaipa G, Golay J, Biondi A, Rambaldi A.

Biol Blood Marrow Transplant. 2017 Dec;23(12):2070-2078. doi: 10.1016/j.bbmt.2017.07.005. Epub 2017 Jul 13.


Unexpected impact of irreversible adsorption on thermal expansion: Adsorbed layers are not that dead.

Braatz ML, Infantas Meléndez L, Sferrazza M, Napolitano S.

J Chem Phys. 2017 May 28;146(20):203304. doi: 10.1063/1.4974834.


Unintentional recurrent laryngeal nerve injuries following thyroidectomy: Is it the surgeon who pays the bill?

Gambardella C, Polistena A, Sanguinetti A, Patrone R, Napolitano S, Esposito D, Testa D, Marotta V, Faggiano A, Calò PG, Avenia N, Conzo G.

Int J Surg. 2017 May;41 Suppl 1:S55-S59. doi: 10.1016/j.ijsu.2017.01.112. Review.


Efficacy and Safety of Mechanical Thrombectomy in Older Adults with Acute Ischemic Stoke.

Sallustio F, Koch G, Motta C, Diomedi M, Alemseged F, D'Agostino VC, Napolitano S, Samà D, Davoli A, Konda D, Morosetti D, Pampana E, Floris R, Gandini R.

J Am Geriatr Soc. 2017 Aug;65(8):1816-1820. doi: 10.1111/jgs.14909. Epub 2017 Apr 19.


How irreversible adsorption affects interfacial properties of polymers.

Napolitano S, Sferrazza M.

Adv Colloid Interface Sci. 2017 Sep;247:172-177. doi: 10.1016/j.cis.2017.02.003. Epub 2017 Feb 9. Review.


Glass transition of polymers in bulk, confined geometries, and near interfaces.

Napolitano S, Glynos E, Tito NB.

Rep Prog Phys. 2017 Mar;80(3):036602. doi: 10.1088/1361-6633/aa5284. Epub 2017 Jan 30.


Staying conductive in the stretch.

Napolitano S.

Science. 2017 Jan 6;355(6320):24-25. doi: 10.1126/science.aal4113. No abstract available.


Irreversible Adsorption Controls Crystallization in Vapor-Deposited Polymer Thin Films.

Jeong H, Napolitano S, Arnold CB, Priestley RD.

J Phys Chem Lett. 2017 Jan 5;8(1):229-234. doi: 10.1021/acs.jpclett.6b02573. Epub 2016 Dec 19.


Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy.

Cossu G, Previtali SC, Napolitano S, Cicalese MP, Tedesco FS, Nicastro F, Noviello M, Roostalu U, Natali Sora MG, Scarlato M, De Pellegrin M, Godi C, Giuliani S, Ciotti F, Tonlorenzi R, Lorenzetti I, Rivellini C, Benedetti S, Gatti R, Marktel S, Mazzi B, Tettamanti A, Ragazzi M, Imro MA, Marano G, Ambrosi A, Fiori R, Sormani MP, Bonini C, Venturini M, Politi LS, Torrente Y, Ciceri F.

EMBO Mol Med. 2016 Dec 1;8(12):1470-1471. doi: 10.15252/emmm.201607129. No abstract available.


Therapeutic value of EGFR inhibition in CRC and NSCLC: 15 years of clinical evidence.

Troiani T, Napolitano S, Della Corte CM, Martini G, Martinelli E, Morgillo F, Ciardiello F.

ESMO Open. 2016 Sep 16;1(5):e000088. eCollection 2016. Review.


Glass Transition Dynamics and Crystallization Kinetics in the Smectic Liquid Crystal 4-n-Butyloxybenzylidene-4'-n'-octylaniline (BBOA).

Jasiurkowska-Delaporte M, Napolitano S, Leys J, Juszyńska-Gałązka E, Wübbenhorst M, Massalska-Arodź M.

J Phys Chem B. 2016 Dec 1;120(47):12160-12167. Epub 2016 Nov 21.


Clinical significance of prophylactic central compartment neck dissection in the treatment of clinically node-negative papillary thyroid cancer patients.

Gambardella C, Tartaglia E, Nunziata A, Izzo G, Siciliano G, Cavallo F, Mauriello C, Napolitano S, Thomas G, Testa D, Rossetti G, Sanguinetti A, Avenia N, Conzo G.

World J Surg Oncol. 2016 Sep 19;14(1):247. doi: 10.1186/s12957-016-1003-5. Review.


Longitudinal MRI quantification of muscle degeneration in Duchenne muscular dystrophy.

Godi C, Ambrosi A, Nicastro F, Previtali SC, Santarosa C, Napolitano S, Iadanza A, Scarlato M, Natali Sora MG, Tettamanti A, Gerevini S, Cicalese MP, Sitzia C, Venturini M, Falini A, Gatti R, Ciceri F, Cossu G, Torrente Y, Politi LS.

Ann Clin Transl Neurol. 2016 Jun 16;3(8):607-22. doi: 10.1002/acn3.319. eCollection 2016 Aug.


Mechanisms of resistance to anti-epidermal growth factor receptor inhibitors in metastatic colorectal cancer.

Sforza V, Martinelli E, Ciardiello F, Gambardella V, Napolitano S, Martini G, Della Corte C, Cardone C, Ferrara ML, Reginelli A, Liguori G, Belli G, Troiani T.

World J Gastroenterol. 2016 Jul 28;22(28):6345-61. doi: 10.3748/wjg.v22.i28.6345. Review.


Bilateral benign multinodular goiter: What is the adequate surgical therapy? A review of literature.

Mauriello C, Marte G, Canfora A, Napolitano S, Pezzolla A, Gambardella C, Tartaglia E, Lanza M, Candela G.

Int J Surg. 2016 Apr;28 Suppl 1:S7-12. doi: 10.1016/j.ijsu.2015.12.041. Epub 2015 Dec 18. Review.

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