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Items: 1 to 50 of 189

1.

RDH1 suppresses adiposity by promoting brown adipose adaptation to fasting and re-feeding.

Krois CR, Vuckovic MG, Huang P, Zaversnik C, Liu CS, Gibson CE, Wheeler MR, Obrochta KM, Min JH, Herber CB, Thompson AC, Shah ID, Gordon SP, Hellerstein MK, Napoli JL.

Cell Mol Life Sci. 2019 Jun;76(12):2425-2447. doi: 10.1007/s00018-019-03046-z. Epub 2019 Feb 20.

PMID:
30788515
2.

DGAT1 inhibits retinol-dependent regulatory T cell formation and mediates autoimmune encephalomyelitis.

Graham KL, Werner BJ, Moyer KM, Patton AK, Krois CR, Yoo HS, Tverskoy M, LaJevic M, Napoli JL, Sobel RA, Zabel BA, Butcher EC.

Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3126-3135. doi: 10.1073/pnas.1817669116. Epub 2019 Feb 4.

3.

Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort.

Thompson GR 3rd, Krois CR, Affolter VK, Everett AD, Varjonen EK, Sharon VR, Singapuri A, Dennis M, McHardy I, Yoo HS, Fedor DM, Wiederhold NP, Aaron PA, Gelli A, Napoli JL, White SD.

Antimicrob Agents Chemother. 2019 Jan 29;63(2). pii: e01384-18. doi: 10.1128/AAC.01384-18. Print 2019 Feb.

4.

Serine Threonine Kinase Receptor-Associated Protein Deficiency Impairs Mouse Embryonic Stem Cells Lineage Commitment Through CYP26A1-Mediated Retinoic Acid Homeostasis.

Jin L, Chang C, Pawlik KM, Datta A, Johnson LM, Vu T, Napoli JL, Datta PK.

Stem Cells. 2018 Sep;36(9):1368-1379. doi: 10.1002/stem.2854. Epub 2018 Jul 17.

5.

Modest Decreases in Endogenous All-trans-Retinoic Acid Produced by a Mouse Rdh10 Heterozygote Provoke Major Abnormalities in Adipogenesis and Lipid Metabolism.

Yang D, Vuckovic MG, Smullin CP, Kim M, Lo CP, Devericks E, Yoo HS, Tintcheva M, Deng Y, Napoli JL.

Diabetes. 2018 Apr;67(4):662-673. doi: 10.2337/db17-0946. Epub 2018 Jan 10.

6.

Raldh1 promotes adiposity during adolescence independently of retinal signaling.

Yang D, Krois CR, Huang P, Wang J, Min J, Yoo HS, Deng Y, Napoli JL.

PLoS One. 2017 Nov 2;12(11):e0187669. doi: 10.1371/journal.pone.0187669. eCollection 2017.

7.

Cellular retinoid binding-proteins, CRBP, CRABP, FABP5: Effects on retinoid metabolism, function and related diseases.

Napoli JL.

Pharmacol Ther. 2017 May;173:19-33. doi: 10.1016/j.pharmthera.2017.01.004. Epub 2017 Jan 27. Review.

8.

Functions of Intracellular Retinoid Binding-Proteins.

Napoli JL.

Subcell Biochem. 2016;81:21-76. Review.

9.

Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice.

Penny HL, Prestwood TR, Bhattacharya N, Sun F, Kenkel JA, Davidson MG, Shen L, Zuniga LA, Seeley ES, Pai R, Choi O, Tolentino L, Wang J, Napoli JL, Engleman EG.

Cancer Immunol Res. 2016 Nov;4(11):917-926. Epub 2016 Sep 16.

10.

Immunotherapy Added to Antibiotic Treatment Reduces Relapse of Disease in a Mouse Model of Tuberculosis.

Mourik BC, Leenen PJ, de Knegt GJ, Huizinga R, van der Eerden BC, Wang J, Krois CR, Napoli JL, Bakker-Woudenberg IA, de Steenwinkel JE.

Am J Respir Cell Mol Biol. 2017 Feb;56(2):233-241. doi: 10.1165/rcmb.2016-0185OC.

PMID:
27654457
11.

Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer.

Bhattacharya N, Yuan R, Prestwood TR, Penny HL, DiMaio MA, Reticker-Flynn NE, Krois CR, Kenkel JA, Pham TD, Carmi Y, Tolentino L, Choi O, Hulett R, Wang J, Winer DA, Napoli JL, Engleman EG.

Immunity. 2016 Sep 20;45(3):641-655. doi: 10.1016/j.immuni.2016.08.008. Epub 2016 Aug 30.

12.

Quantitation of retinaldehyde in small biological samples using ultrahigh-performance liquid chromatography tandem mass spectrometry.

Wang J, Yoo HS, Obrochta KM, Huang P, Napoli JL.

Anal Biochem. 2015 Sep 1;484:162-8. doi: 10.1016/j.ab.2015.05.016. Epub 2015 Jun 1.

13.

Insulin regulates retinol dehydrogenase expression and all-trans-retinoic acid biosynthesis through FoxO1.

Obrochta KM, Krois CR, Campos B, Napoli JL.

J Biol Chem. 2015 Mar 13;290(11):7259-68. doi: 10.1074/jbc.M114.609313. Epub 2015 Jan 27.

14.

Dependence of brown adipose tissue function on CD36-mediated coenzyme Q uptake.

Anderson CM, Kazantzis M, Wang J, Venkatraman S, Goncalves RL, Quinlan CL, Ng R, Jastroch M, Benjamin DI, Nie B, Herber C, Van AA, Park MJ, Yun D, Chan K, Yu A, Vuong P, Febbraio M, Nomura DK, Napoli JL, Brand MD, Stahl A.

Cell Rep. 2015 Feb 3;10(4):505-15. doi: 10.1016/j.celrep.2014.12.048. Epub 2015 Jan 22.

15.

Vitamin A metabolism and mucosal immune function are distinct between BALB/c and C57BL/6 mice.

Goverse G, Olivier BJ, Molenaar R, Knippenberg M, Greuter M, Konijn T, Cook EC, Beijer MR, Fedor DM, den Haan JM, Napoli JL, Bouma G, Mebius RE.

Eur J Immunol. 2015 Jan;45(1):89-100. doi: 10.1002/eji.201343340. Epub 2014 Nov 17.

16.

Consumption of clarified grapefruit juice ameliorates high-fat diet induced insulin resistance and weight gain in mice.

Chudnovskiy R, Thompson A, Tharp K, Hellerstein M, Napoli JL, Stahl A.

PLoS One. 2014 Oct 8;9(10):e108408. doi: 10.1371/journal.pone.0108408. eCollection 2014.

17.

Retinoic acid biosynthesis is impaired in human and murine endometriosis.

Pierzchalski K, Taylor RN, Nezhat C, Jones JW, Napoli JL, Yang G, Kane MA, Sidell N.

Biol Reprod. 2014 Oct;91(4):84. doi: 10.1095/biolreprod.114.119677. Epub 2014 Aug 20.

18.

Effects of diet and strain on mouse serum and tissue retinoid concentrations.

Obrochta KM, Kane MA, Napoli JL.

PLoS One. 2014 Jun 9;9(6):e99435. doi: 10.1371/journal.pone.0099435. eCollection 2014.

19.

Retinoic acid controls the homeostasis of pre-cDC-derived splenic and intestinal dendritic cells.

Klebanoff CA, Spencer SP, Torabi-Parizi P, Grainger JR, Roychoudhuri R, Ji Y, Sukumar M, Muranski P, Scott CD, Hall JA, Ferreyra GA, Leonardi AJ, Borman ZA, Wang J, Palmer DC, Wilhelm C, Cai R, Sun J, Napoli JL, Danner RL, Gattinoni L, Belkaid Y, Restifo NP.

J Exp Med. 2013 Sep 23;210(10):1961-76. doi: 10.1084/jem.20122508. Epub 2013 Sep 2.

20.

Analysis of follicular fluid retinoids in women undergoing in vitro fertilization: retinoic acid influences embryo quality and is reduced in women with endometriosis.

Pauli SA, Session DR, Shang W, Easley K, Wieser F, Taylor RN, Pierzchalski K, Napoli JL, Kane MA, Sidell N.

Reprod Sci. 2013 Sep;20(9):1116-24. doi: 10.1177/1933719113477487. Epub 2013 Feb 20.

21.

The retinol dehydrogenase Rdh10 localizes to lipid droplets during acyl ester biosynthesis.

Jiang W, Napoli JL.

J Biol Chem. 2013 Jan 4;288(1):589-97. doi: 10.1074/jbc.M112.402883. Epub 2012 Nov 15.

22.

Endogenous retinoids in the pathogenesis of alopecia areata.

Duncan FJ, Silva KA, Johnson CJ, King BL, Szatkiewicz JP, Kamdar SP, Ong DE, Napoli JL, Wang J, King LE Jr, Whiting DA, McElwee KJ, Sundberg JP, Everts HB.

J Invest Dermatol. 2013 Feb;133(2):334-43. doi: 10.1038/jid.2012.344. Epub 2012 Sep 27.

23.

A retinoic acid--rich tumor microenvironment provides clonal survival cues for tumor-specific CD8(+) T cells.

Guo Y, Pino-Lagos K, Ahonen CA, Bennett KA, Wang J, Napoli JL, Blomhoff R, Sockanathan S, Chandraratna RA, Dmitrovsky E, Turk MJ, Noelle RJ.

Cancer Res. 2012 Oct 15;72(20):5230-9. doi: 10.1158/0008-5472.CAN-12-1727. Epub 2012 Aug 17.

24.

Reorganization of cellular retinol-binding protein type 1 and lecithin:retinol acyltransferase during retinyl ester biosynthesis.

Jiang W, Napoli JL.

Biochim Biophys Acta. 2012 Jul;1820(7):859-69. doi: 10.1016/j.bbagen.2012.03.016. Epub 2012 Apr 2.

25.

Identification of RALDH2 as a visually regulated retinoic acid synthesizing enzyme in the chick choroid.

Rada JA, Hollaway LR, Lam W, Li N, Napoli JL.

Invest Ophthalmol Vis Sci. 2012 Mar 26;53(3):1649-62. doi: 10.1167/iovs.11-8444. Print 2012 Mar.

26.

Morphological defects in a novel Rdh10 mutant that has reduced retinoic acid biosynthesis and signaling.

Ashique AM, May SR, Kane MA, Folias AE, Phamluong K, Choe Y, Napoli JL, Peterson AS.

Genesis. 2012 May;50(5):415-23. doi: 10.1002/dvg.22002. Epub 2012 Jan 25.

27.

Effects of ethanol on physiological retinoic acid levels.

Napoli JL.

IUBMB Life. 2011 Sep;63(9):701-6. doi: 10.1002/iub.500. Epub 2011 Jul 15. Review.

28.

CrbpI modulates glucose homeostasis and pancreas 9-cis-retinoic acid concentrations.

Kane MA, Folias AE, Pingitore A, Perri M, Krois CR, Ryu JY, Cione E, Napoli JL.

Mol Cell Biol. 2011 Aug;31(16):3277-85. doi: 10.1128/MCB.05516-11. Epub 2011 Jun 13.

29.

Physiological insights into all-trans-retinoic acid biosynthesis.

Napoli JL.

Biochim Biophys Acta. 2012 Jan;1821(1):152-67. doi: 10.1016/j.bbalip.2011.05.004. Epub 2011 May 19. Review.

30.

MyD88 and retinoic acid signaling pathways interact to modulate gastrointestinal activities of dendritic cells.

Villablanca EJ, Wang S, de Calisto J, Gomes DC, Kane MA, Napoli JL, Blaner WS, Kagechika H, Blomhoff R, Rosemblatt M, Bono MR, von Andrian UH, Mora JR.

Gastroenterology. 2011 Jul;141(1):176-85. doi: 10.1053/j.gastro.2011.04.010. Epub 2011 Apr 16.

31.

Binding affinities of CRBPI and CRBPII for 9-cis-retinoids.

Kane MA, Bright FV, Napoli JL.

Biochim Biophys Acta. 2011 May;1810(5):514-8. doi: 10.1016/j.bbagen.2011.02.009. Epub 2011 Mar 5.

32.

Role of the retinoic acid receptor-α in HIV-associated nephropathy.

Ratnam KK, Feng X, Chuang PY, Verma V, Lu TC, Wang J, Jin Y, Farias EF, Napoli JL, Chen N, Kaufman L, Takano T, D'Agati VD, Klotman PE, He JC.

Kidney Int. 2011 Mar;79(6):624-634. doi: 10.1038/ki.2010.470. Epub 2010 Dec 8.

33.

Multiple retinol and retinal dehydrogenases catalyze all-trans-retinoic acid biosynthesis in astrocytes.

Wang C, Kane MA, Napoli JL.

J Biol Chem. 2011 Feb 25;286(8):6542-53. doi: 10.1074/jbc.M110.198382. Epub 2010 Dec 7.

34.

Identification of 9-cis-retinoic acid as a pancreas-specific autacoid that attenuates glucose-stimulated insulin secretion.

Kane MA, Folias AE, Pingitore A, Perri M, Obrochta KM, Krois CR, Cione E, Ryu JY, Napoli JL.

Proc Natl Acad Sci U S A. 2010 Dec 14;107(50):21884-9. doi: 10.1073/pnas.1008859107. Epub 2010 Nov 29.

35.

Endogenous retinoids in mammalian growth plate cartilage: analysis and roles in matrix homeostasis and turnover.

Williams JA, Kane M, Okabe T, Enomoto-Iwamoto M, Napoli JL, Pacifici M, Iwamoto M.

J Biol Chem. 2010 Nov 19;285(47):36674-81. doi: 10.1074/jbc.M110.151878. Epub 2010 Sep 14.

36.

Altered retinoic acid metabolism in diabetic mouse kidney identified by O isotopic labeling and 2D mass spectrometry.

Starkey JM, Zhao Y, Sadygov RG, Haidacher SJ, Lejeune WS, Dey N, Luxon BA, Kane MA, Napoli JL, Denner L, Tilton RG.

PLoS One. 2010 Jun 14;5(6):e11095. doi: 10.1371/journal.pone.0011095.

37.

Quantification of endogenous retinoids.

Kane MA, Napoli JL.

Methods Mol Biol. 2010;652:1-54. doi: 10.1007/978-1-60327-325-1_1.

38.

Vitamin A facilitates enteric nervous system precursor migration by reducing Pten accumulation.

Fu M, Sato Y, Lyons-Warren A, Zhang B, Kane MA, Napoli JL, Heuckeroth RO.

Development. 2010 Feb;137(4):631-40. doi: 10.1242/dev.040550.

39.

Retinoic acid is a cofactor for translational regulation of vascular endothelial growth factor in human endometrial stromal cells.

Sidell N, Feng Y, Hao L, Wu J, Yu J, Kane MA, Napoli JL, Taylor RN.

Mol Endocrinol. 2010 Jan;24(1):148-60. doi: 10.1210/me.2009-0155. Epub 2009 Nov 12.

40.
41.

Retinoic acid from the meninges regulates cortical neuron generation.

Siegenthaler JA, Ashique AM, Zarbalis K, Patterson KP, Hecht JH, Kane MA, Folias AE, Choe Y, May SR, Kume T, Napoli JL, Peterson AS, Pleasure SJ.

Cell. 2009 Oct 30;139(3):597-609. doi: 10.1016/j.cell.2009.10.004. Erratum in: Cell. 2011 Aug 5;146(3):486.

42.

Rdh12 activity and effects on retinoid processing in the murine retina.

Chrispell JD, Feathers KL, Kane MA, Kim CY, Brooks M, Khanna R, Kurth I, Hübner CA, Gal A, Mears AJ, Swaroop A, Napoli JL, Sparrow JR, Thompson DA.

J Biol Chem. 2009 Aug 7;284(32):21468-77. doi: 10.1074/jbc.M109.020966. Epub 2009 Jun 8.

43.

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse.

Williams JA, Kondo N, Okabe T, Takeshita N, Pilchak DM, Koyama E, Ochiai T, Jensen D, Chu ML, Kane MA, Napoli JL, Enomoto-Iwamoto M, Ghyselinck N, Chambon P, Pacifici M, Iwamoto M.

Dev Biol. 2009 Apr 15;328(2):315-27. doi: 10.1016/j.ydbio.2009.01.031. Epub 2009 Feb 3.

44.

Retinol Esterification by DGAT1 Is Essential for Retinoid Homeostasis in Murine Skin.

Shih MY, Kane MA, Zhou P, Yen CL, Streeper RS, Napoli JL, Farese RV Jr.

J Biol Chem. 2009 Feb 13;284(7):4292-9. doi: 10.1074/jbc.M807503200. Epub 2008 Nov 20.

45.

The nuclear transcription factor RARalpha associates with neuronal RNA granules and suppresses translation.

Chen N, Onisko B, Napoli JL.

J Biol Chem. 2008 Jul 25;283(30):20841-7. doi: 10.1074/jbc.M802314200. Epub 2008 May 21.

46.

HPLC/UV quantitation of retinal, retinol, and retinyl esters in serum and tissues.

Kane MA, Folias AE, Napoli JL.

Anal Biochem. 2008 Jul 1;378(1):71-9. doi: 10.1016/j.ab.2008.03.038. Epub 2008 Mar 25.

47.

Quantitative profiling of endogenous retinoic acid in vivo and in vitro by tandem mass spectrometry.

Kane MA, Folias AE, Wang C, Napoli JL.

Anal Chem. 2008 Mar 1;80(5):1702-8. doi: 10.1021/ac702030f. Epub 2008 Feb 6.

48.
49.

Gestational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin alters retinoid homeostasis in maternal and perinatal tissues of the Holtzman rat.

Kransler KM, Tonucci DA, McGarrigle BP, Napoli JL, Olson JR.

Toxicol Appl Pharmacol. 2007 Oct 1;224(1):29-38. Epub 2007 Jun 26.

PMID:
17655899
50.

Altered vitamin A homeostasis and increased size and adiposity in the rdh1-null mouse.

Zhang M, Hu P, Krois CR, Kane MA, Napoli JL.

FASEB J. 2007 Sep;21(11):2886-96. Epub 2007 Apr 13.

PMID:
17435174

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