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Items: 1 to 50 of 245

1.

Nutritional enhancement in plants - green and greener.

Napier JA, Sayanova O.

Curr Opin Biotechnol. 2020 Feb;61:122-127. doi: 10.1016/j.copbio.2019.12.010. Epub 2020 Jan 3. Review.

2.

Impairment of DHA synthesis alters the expression of neuronal plasticity markers and the brain inflammatory status in mice.

Talamonti E, Sasso V, To H, Haslam RP, Napier JA, Ulfhake B, Pernold K, Asadi A, Hessa T, Jacobsson A, Chiurchiù V, Viscomi MT.

FASEB J. 2020 Feb;34(2):2024-2040. doi: 10.1096/fj.201901890RR. Epub 2019 Dec 11.

PMID:
31909582
3.

Arabidopsis cytosolic acyl-CoA-binding proteins function in determining seed oil composition.

Guo ZH, Ye ZW, Haslam RP, Michaelson LV, Napier JA, Chye ML.

Plant Direct. 2019 Dec 4;3(12):e00182. doi: 10.1002/pld3.182. eCollection 2019 Dec.

4.

The overexpression of rice ACYL-CoA-BINDING PROTEIN2 increases grain size and bran oil content in transgenic rice.

Guo ZH, Haslam RP, Michaelson LV, Yeung EC, Lung SC, Napier JA, Chye ML.

Plant J. 2019 Dec;100(6):1132-1147. doi: 10.1111/tpj.14503. Epub 2019 Sep 21.

PMID:
31437323
5.

Multifunctionalizing the marine diatom Phaeodactylum tricornutum for sustainable co-production of omega-3 long chain polyunsaturated fatty acids and recombinant phytase.

Pudney A, Gandini C, Economou CK, Smith R, Goddard P, Napier JA, Spicer A, Sayanova O.

Sci Rep. 2019 Aug 7;9(1):11444. doi: 10.1038/s41598-019-47875-1.

6.

Sphingolipids: towards an integrated view of metabolism during the plant stress response.

Huby E, Napier JA, Baillieul F, Michaelson LV, Dhondt-Cordelier S.

New Phytol. 2020 Jan;225(2):659-670. doi: 10.1111/nph.15997. Epub 2019 Jul 15.

7.

The challenges of delivering genetically modified crops with nutritional enhancement traits.

Napier JA, Haslam RP, Tsalavouta M, Sayanova O.

Nat Plants. 2019 Jun;5(6):563-567. doi: 10.1038/s41477-019-0430-z. Epub 2019 Jun 3. Review.

PMID:
31160704
8.

Postprandial incorporation of EPA and DHA from transgenic Camelina sativa oil into blood lipids is equivalent to that from fish oil in healthy humans.

West AL, Miles EA, Lillycrop KA, Han L, Sayanova O, Napier JA, Calder PC, Burdge GC.

Br J Nutr. 2019 Jun;121(11):1235-1246. doi: 10.1017/S0007114519000825. Epub 2019 Apr 12.

9.

Omega-3 Long-Chain Polyunsaturated Fatty Acids, EPA and DHA: Bridging the Gap between Supply and Demand.

Tocher DR, Betancor MB, Sprague M, Olsen RE, Napier JA.

Nutrients. 2019 Jan 4;11(1). pii: E89. doi: 10.3390/nu11010089. Review.

10.

Europe's first and last field trial of gene-edited plants?

Faure JD, Napier JA.

Elife. 2018 Dec 18;7. pii: e42379. doi: 10.7554/eLife.42379.

11.

Update on GM canola crops as novel sources of omega-3 fish oils.

Napier JA, Olsen RE, Tocher DR.

Plant Biotechnol J. 2019 Apr;17(4):703-705. doi: 10.1111/pbi.13045. Epub 2018 Dec 13. No abstract available.

12.

Oil from transgenic Camelina sativa containing over 25 % n-3 long-chain PUFA as the major lipid source in feed for Atlantic salmon (Salmo salar).

Betancor MB, Li K, Bucerzan VS, Sprague M, Sayanova O, Usher S, Han L, Norambuena F, Torrissen O, Napier JA, Tocher DR, Olsen RE.

Br J Nutr. 2018 Jun;119(12):1378-1392. doi: 10.1017/S0007114518001125.

PMID:
29845899
13.

A transatlantic perspective on 20 emerging issues in biological engineering.

Wintle BC, Boehm CR, Rhodes C, Molloy JC, Millett P, Adam L, Breitling R, Carlson R, Casagrande R, Dando M, Doubleday R, Drexler E, Edwards B, Ellis T, Evans NG, Hammond R, Haseloff J, Kahl L, Kuiken T, Lichman BR, Matthewman CA, Napier JA, ÓhÉigeartaigh SS, Patron NJ, Perello E, Shapira P, Tait J, Takano E, Sutherland WJ.

Elife. 2017 Nov 14;6. pii: e30247. doi: 10.7554/eLife.30247.

14.

Tailoring seed oil composition in the real world: optimising omega-3 long chain polyunsaturated fatty acid accumulation in transgenic Camelina sativa.

Usher S, Han L, Haslam RP, Michaelson LV, Sturtevant D, Aziz M, Chapman KD, Sayanova O, Napier JA.

Sci Rep. 2017 Jul 26;7(1):6570. doi: 10.1038/s41598-017-06838-0.

15.

Modulation of lipid biosynthesis by stress in diatoms.

Sayanova O, Mimouni V, Ulmann L, Morant-Manceau A, Pasquet V, Schoefs B, Napier JA.

Philos Trans R Soc Lond B Biol Sci. 2017 Sep 5;372(1728). pii: 20160407. doi: 10.1098/rstb.2016.0407. Review.

16.

Erratum to: Replacement of Marine Fish Oil with de novo Omega-3 Oils from Transgenic Camelina sativa in Feeds for Gilthead Sea Bream (Sparus aurata L.).

Betancor MB, Sprague M, Montero D, Usher S, Sayanova O, Campbell PJ, Napier JA, Caballero MJ, Izquierdo M, Tocher DR.

Lipids. 2017 May;52(5):463. doi: 10.1007/s11745-017-4248-z. No abstract available.

17.

An oil containing EPA and DHA from transgenic Camelina sativa to replace marine fish oil in feeds for Atlantic salmon (Salmo salar L.): Effects on intestinal transcriptome, histology, tissue fatty acid profiles and plasma biochemistry.

Betancor MB, Li K, Sprague M, Bardal T, Sayanova O, Usher S, Han L, Måsøval K, Torrissen O, Napier JA, Tocher DR, Olsen RE.

PLoS One. 2017 Apr 12;12(4):e0175415. doi: 10.1371/journal.pone.0175415. eCollection 2017.

18.

Chlamydomonas carries out fatty acid β-oxidation in ancestral peroxisomes using a bona fide acyl-CoA oxidase.

Kong F, Liang Y, Légeret B, Beyly-Adriano A, Blangy S, Haslam RP, Napier JA, Beisson F, Peltier G, Li-Beisson Y.

Plant J. 2017 Apr;90(2):358-371. doi: 10.1111/tpj.13498. Epub 2017 Mar 20.

19.

Tailoring the composition of novel wax esters in the seeds of transgenic Camelina sativa through systematic metabolic engineering.

Ruiz-Lopez N, Broughton R, Usher S, Salas JJ, Haslam RP, Napier JA, Beaudoin F.

Plant Biotechnol J. 2017 Jul;15(7):837-849. doi: 10.1111/pbi.12679. Epub 2017 Feb 2.

20.

Sunflower HaGPAT9-1 is the predominant GPAT during seed development.

Payá-Milans M, Aznar-Moreno JA, Balbuena TS, Haslam RP, Gidda SK, Pérez-Hormaeche J, Mullen RT, Thelen JJ, Napier JA, Salas JJ, Garcés R, Martínez-Force E, Venegas-Calerón M.

Plant Sci. 2016 Nov;252:42-52. doi: 10.1016/j.plantsci.2016.07.002. Epub 2016 Jul 9.

PMID:
27717477
21.

Replacement of Marine Fish Oil with de novo Omega-3 Oils from Transgenic Camelina sativa in Feeds for Gilthead Sea Bream (Sparus aurata L.).

Betancor MB, Sprague M, Montero D, Usher S, Sayanova O, Campbell PJ, Napier JA, Caballero MJ, Izquierdo M, Tocher DR.

Lipids. 2016 Oct;51(10):1171-1191. doi: 10.1007/s11745-016-4191-4. Epub 2016 Sep 2. Erratum in: Lipids. 2017 May;52(5):463.

22.

Towards the development of a sustainable soya bean-based feedstock for aquaculture.

Park H, Weier S, Razvi F, Peña PA, Sims NA, Lowell J, Hungate C, Kissinger K, Key G, Fraser P, Napier JA, Cahoon EB, Clemente TE.

Plant Biotechnol J. 2017 Feb;15(2):227-236. doi: 10.1111/pbi.12608. Epub 2016 Sep 13.

23.

Synthetic redesign of plant lipid metabolism.

Haslam RP, Sayanova O, Kim HJ, Cahoon EB, Napier JA.

Plant J. 2016 Jul;87(1):76-86. doi: 10.1111/tpj.13172. Epub 2016 Jun 20. Review.

24.

Nutritional Evaluation of an EPA-DHA Oil from Transgenic Camelina sativa in Feeds for Post-Smolt Atlantic Salmon (Salmo salar L.).

Betancor MB, Sprague M, Sayanova O, Usher S, Metochis C, Campbell PJ, Napier JA, Tocher DR.

PLoS One. 2016 Jul 25;11(7):e0159934. doi: 10.1371/journal.pone.0159934. eCollection 2016.

25.

Plant sphingolipids: Their importance in cellular organization and adaption.

Michaelson LV, Napier JA, Molino D, Faure JD.

Biochim Biophys Acta. 2016 Sep;1861(9 Pt B):1329-1335. doi: 10.1016/j.bbalip.2016.04.003. Epub 2016 Apr 13. Review.

26.

Field trial evaluation of the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Camelina sativa: Making fish oil substitutes in plants.

Usher S, Haslam RP, Ruiz-Lopez N, Sayanova O, Napier JA.

Metab Eng Commun. 2015 Jul 9;2:93-98. eCollection 2015 Dec.

27.

Correction: The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis.

Hématy K, Bellec Y, Podicheti R, Bouteiller N, Anne P, Morineau C, Haslam RP, Beaudoin F, Napier JA, Mockaitis K, Gagliardi D, Vaucheret H, Lange H, Faure JD.

PLoS Genet. 2016 Mar 23;12(3):e1005958. doi: 10.1371/journal.pgen.1005958. eCollection 2016 Mar. No abstract available.

28.

Heterotrophic Production of Omega-3 Long-Chain Polyunsaturated Fatty Acids by Trophically Converted Marine Diatom Phaeodactylum tricornutum.

Hamilton ML, Powers S, Napier JA, Sayanova O.

Mar Drugs. 2016 Mar 9;14(3). pii: E53. doi: 10.3390/md14030053.

29.

Transgenic plants as a sustainable, terrestrial source of fish oils.

Napier JA, Usher S, Haslam RP, Ruiz-Lopez N, Sayanova O.

Eur J Lipid Sci Technol. 2015 Sep;117(9):1317-1324. Epub 2015 Jun 23.

30.

The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis.

Hématy K, Bellec Y, Podicheti R, Bouteiller N, Anne P, Morineau C, Haslam RP, Beaudoin F, Napier JA, Mockaitis K, Gagliardi D, Vaucheret H, Lange H, Faure JD.

PLoS Genet. 2016 Feb 1;12(2):e1005817. doi: 10.1371/journal.pgen.1005817. eCollection 2016 Feb. Erratum in: PLoS Genet. 2016 Mar;12(3):e1005958.

31.

A Transgenic Camelina sativa Seed Oil Effectively Replaces Fish Oil as a Dietary Source of Eicosapentaenoic Acid in Mice.

Tejera N, Vauzour D, Betancor MB, Sayanova O, Usher S, Cochard M, Rigby N, Ruiz-Lopez N, Menoyo D, Tocher DR, Napier JA, Minihane AM.

J Nutr. 2016 Feb;146(2):227-35. doi: 10.3945/jn.115.223941. Epub 2016 Jan 20.

32.

Towards the Industrial Production of Omega-3 Long Chain Polyunsaturated Fatty Acids from a Genetically Modified Diatom Phaeodactylum tricornutum.

Hamilton ML, Warwick J, Terry A, Allen MJ, Napier JA, Sayanova O.

PLoS One. 2015 Dec 14;10(12):e0144054. doi: 10.1371/journal.pone.0144054. eCollection 2015.

33.

Evaluation of a high-EPA oil from transgenic Camelina sativa in feeds for Atlantic salmon (Salmo salar L.): Effects on tissue fatty acid composition, histology and gene expression.

Betancor MB, Sprague M, Sayanova O, Usher S, Campbell PJ, Napier JA, Caballero MJ, Tocher DR.

Aquaculture. 2015 Jul 1;444:1-12.

34.

The first crop plant genetically engineered to release an insect pheromone for defence.

Bruce TJA, Aradottir GI, Smart LE, Martin JL, Caulfield JC, Doherty A, Sparks CA, Woodcock CM, Birkett MA, Napier JA, Jones HD, Pickett JA.

Sci Rep. 2015 Jun 25;5:11183. doi: 10.1038/srep11183.

35.

Intragenus competition between coccolithoviruses: an insight on how a select few can come to dominate many.

Nissimov JI, Napier JA, Allen MJ, Kimmance SA.

Environ Microbiol. 2016 Jan;18(1):133-45. doi: 10.1111/1462-2920.12902. Epub 2015 Jun 25.

PMID:
25970076
36.

Sphingolipid metabolism is strikingly different between pollen and leaf in Arabidopsis as revealed by compositional and gene expression profiling.

Luttgeharm KD, Kimberlin AN, Cahoon RE, Cerny RL, Napier JA, Markham JE, Cahoon EB.

Phytochemistry. 2015 Jul;115:121-9. doi: 10.1016/j.phytochem.2015.02.019. Epub 2015 Mar 17.

PMID:
25794895
37.

Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development.

Hsiao AS, Haslam RP, Michaelson LV, Liao P, Chen QF, Sooriyaarachchi S, Mowbray SL, Napier JA, Tanner JA, Chye ML.

Biosci Rep. 2015 Feb 25;35(1). pii: e00176. No abstract available.

38.

Molecular characterization of two isoforms of a farnesyl pyrophosphate synthase gene in wheat and their roles in sesquiterpene synthesis and inducible defence against aphid infestation.

Zhang Y, Li ZX, Yu XD, Fan J, Pickett JA, Jones HD, Zhou JJ, Birkett MA, Caulfield J, Napier JA, Zhao GY, Cheng XG, Shi Y, Bruce TJ, Xia LQ.

New Phytol. 2015 May;206(3):1101-15. doi: 10.1111/nph.13302. Epub 2015 Jan 30.

39.

An alternative pathway for the effective production of the omega-3 long-chain polyunsaturates EPA and ETA in transgenic oilseeds.

Ruiz-Lopez N, Haslam RP, Usher S, Napier JA, Sayanova O.

Plant Biotechnol J. 2015 Dec;13(9):1264-75. doi: 10.1111/pbi.12328. Epub 2015 Jan 30.

40.

A nutritionally-enhanced oil from transgenic Camelina sativa effectively replaces fish oil as a source of eicosapentaenoic acid for fish.

Betancor MB, Sprague M, Usher S, Sayanova O, Campbell PJ, Napier JA, Tocher DR.

Sci Rep. 2015 Jan 29;5:8104. doi: 10.1038/srep08104.

41.

ECERIFERUM2-LIKE proteins have unique biochemical and physiological functions in very-long-chain fatty acid elongation.

Haslam TM, Haslam R, Thoraval D, Pascal S, Delude C, Domergue F, Fernández AM, Beaudoin F, Napier JA, Kunst L, Joubès J.

Plant Physiol. 2015 Mar;167(3):682-92. doi: 10.1104/pp.114.253195. Epub 2015 Jan 16.

42.

Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5 and ACBP6 have overlapping but distinct roles in seed development.

Hsiao AS, Haslam RP, Michaelson LV, Liao P, Chen QF, Sooriyaarachchi S, Mowbray SL, Napier JA, Tanner JA, Chye ML.

Biosci Rep. 2014 Dec 23;34(6):e00165. doi: 10.1042/BSR20140139. Erratum in: Biosci Rep. 2015;35(1). pii: e00176.

43.

Modifying the lipid content and composition of plant seeds: engineering the production of LC-PUFA.

Ruiz-Lopez N, Usher S, Sayanova OV, Napier JA, Haslam RP.

Appl Microbiol Biotechnol. 2015 Jan;99(1):143-54. doi: 10.1007/s00253-014-6217-2. Epub 2014 Nov 25. Review.

44.

Modifying fatty acid profiles through a new cytokinin-based plastid transformation system.

Dunne A, Maple-Grødem J, Gargano D, Haslam RP, Napier JA, Chua NH, Russell R, Møller SG.

Plant J. 2014 Dec;80(6):1131-8. doi: 10.1111/tpj.12684. Epub 2014 Nov 13.

45.

Gene expression in plant lipid metabolism in Arabidopsis seedlings.

Hsiao AS, Haslam RP, Michaelson LV, Liao P, Napier JA, Chye ML.

PLoS One. 2014 Sep 29;9(9):e107372. doi: 10.1371/journal.pone.0107372. eCollection 2014.

46.

Rice ORMDL controls sphingolipid homeostasis affecting fertility resulting from abnormal pollen development.

Chueasiri C, Chunthong K, Pitnjam K, Chakhonkaen S, Sangarwut N, Sangsawang K, Suksangpanomrung M, Michaelson LV, Napier JA, Muangprom A.

PLoS One. 2014 Sep 5;9(9):e106386. doi: 10.1371/journal.pone.0106386. eCollection 2014.

47.

Gluten quality of bread wheat is associated with activity of RabD GTPases.

Tyler AM, Bhandari DG, Poole M, Napier JA, Jones HD, Lu C, Lycett GW.

Plant Biotechnol J. 2015 Feb;13(2):163-76. doi: 10.1111/pbi.12231. Epub 2014 Jul 22.

48.

Understanding and manipulating plant lipid composition: Metabolic engineering leads the way.

Napier JA, Haslam RP, Beaudoin F, Cahoon EB.

Curr Opin Plant Biol. 2014 Jun;19:68-75. doi: 10.1016/j.pbi.2014.04.001. Epub 2014 May 6.

49.

Permanent draft genomes of four new coccolithoviruses: EhV-18, EhV-145, EhV-156 and EhV-164.

Nissimov JI, Napier JA, Kimmance SA, Allen MJ.

Mar Genomics. 2014 Jun;15:7-8. doi: 10.1016/j.margen.2014.02.004. Epub 2014 Mar 13.

PMID:
24631268
50.

Delivering sustainable crop protection systems via the seed: exploiting natural constitutive and inducible defence pathways.

Pickett JA, Aradottír GI, Birkett MA, Bruce TJ, Hooper AM, Midega CA, Jones HD, Matthes MC, Napier JA, Pittchar JO, Smart LE, Woodcock CM, Khan ZR.

Philos Trans R Soc Lond B Biol Sci. 2014 Feb 17;369(1639):20120281. doi: 10.1098/rstb.2012.0281. Print 2014 Apr 5. Review. Erratum in: Philos Trans R Soc Lond B Biol Sci. 2014 May 19;369(1642):20140053.

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