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Items: 1 to 50 of 148

1.

Direct and indirect mapping of intramural space in ventricular tachycardia.

Bhaskaran A, Nayyar S, Porta-Sánchez A, Jons C, Massé S, Magtibay K, Aukhojee P, Ha A, Bokhari M, Tung R, Downar E, Nanthakumar K.

Heart Rhythm. 2019 Oct 15. pii: S1547-5271(19)30923-3. doi: 10.1016/j.hrthm.2019.10.017. [Epub ahead of print]

PMID:
31622782
2.

Empirical mode decomposition based ECG features in classifying and tracking ventricular arrhythmias.

Hotradat M, Balasundaram K, Masse S, Nair K, Nanthakumar K, Umapathy K.

Comput Biol Med. 2019 Sep;112:103379. doi: 10.1016/j.compbiomed.2019.103379. Epub 2019 Aug 3.

PMID:
31419628
3.

Reinserting Physiology into Cardiac Mapping Using Omnipolar Electrograms.

Magtibay K, Porta-Sánchez A, Haldar SK, Deno DC, Massé S, Nanthakumar K.

Card Electrophysiol Clin. 2019 Sep;11(3):525-536. doi: 10.1016/j.ccep.2019.05.003. Review.

4.

Lateral tunnel Fontan atrial tachycardia ablation trans-baffle access is not mandatory as the initial strategy.

Bhaskaran A, Nayyar S, Charla P, Saeed Y, Haldar S, Porta-Sánchez A, Kugamoorthy P, Hans A, Jons C, Oechslin E, Hickey E, Harris L, Silversides C, Roche SL, Downar E, Nanthakumar K, Nair K.

J Interv Card Electrophysiol. 2019 Aug 9. doi: 10.1007/s10840-019-00580-5. [Epub ahead of print]

PMID:
31399922
5.

Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate the Infarcted Pig Heart but Induce Ventricular Tachyarrhythmias.

Romagnuolo R, Masoudpour H, Porta-Sánchez A, Qiang B, Barry J, Laskary A, Qi X, Massé S, Magtibay K, Kawajiri H, Wu J, Valdman Sadikov T, Rothberg J, Panchalingam KM, Titus E, Li RK, Zandstra PW, Wright GA, Nanthakumar K, Ghugre NR, Keller G, Laflamme MA.

Stem Cell Reports. 2019 May 14;12(5):967-981. doi: 10.1016/j.stemcr.2019.04.005. Epub 2019 May 2.

6.

Health Care Utilization After Ventricular Tachycardia Ablation: A Propensity Score-Matched Cohort Study.

Porta-Sánchez A, Ha ACT, Wang X, Almehmadi F, Austin PC, Fischer HD, Al-Qubbany A, Chemello D, Chauhan V, Downar E, Lee DS, Nanthakumar K.

Can J Cardiol. 2019 Feb;35(2):169-177. doi: 10.1016/j.cjca.2018.10.011. Epub 2018 Oct 25.

PMID:
30760423
7.

Omnipolarity applied to equi-spaced electrode array for ventricular tachycardia substrate mapping.

Porta-Sánchez A, Magtibay K, Nayyar S, Bhaskaran A, Lai PFH, Massé S, Labos C, Qiang B, Romagnuolo R, Masoudpour H, Biswas L, Ghugre N, Laflamme M, Deno DC, Nanthakumar K.

Europace. 2019 May 1;21(5):813-821. doi: 10.1093/europace/euy304.

8.

Exit sites on the epicardium rarely subtend critical diastolic path of ischemic VT on the endocardium: Implications for noninvasive ablation.

Bhaskaran A, Nayyar S, Porta-Sánchez A, Haldar S, Bokhari M, Massé S, Liang T, Zehra N, Farid T, Downar E, Nanthakumar K.

J Cardiovasc Electrophysiol. 2019 Apr;30(4):520-527. doi: 10.1111/jce.13843. Epub 2019 Jan 15.

PMID:
30614114
9.

Safety of Chronic Cardiac Ryanodine Receptor Modulation: A 10-Year Experience.

Bokhari MM, Spears DA, Lai PF, Si D, Billia F, Parker JD, Al-Hesayen AO, Azam MA, Riazi S, Nanthakumar K.

JACC Clin Electrophysiol. 2018 Nov;4(11):1480-1481. doi: 10.1016/j.jacep.2018.08.001. No abstract available.

10.

Information theory to tachycardia therapy: electrogram entropy predicts diastolic microstructure of reentrant ventricular tachycardia.

Nayyar S, Downar E, Beheshti M, Liang T, Massé S, Magtibay K, Bhaskaran A, Saeed Y, Vigmond E, Nanthakumar K.

Am J Physiol Heart Circ Physiol. 2019 Jan 1;316(1):H134-H144. doi: 10.1152/ajpheart.00581.2018. Epub 2018 Oct 19.

PMID:
30339499
11.

Determinants of atrial bipolar voltage: Inter electrode distance and wavefront angle.

Beheshti M, Magtibay K, Massé S, Porta-Sanchez A, Haldar S, Bhaskaran A, Nayyar S, Glover B, Deno DC, Vigmond EJ, Nanthakumar K.

Comput Biol Med. 2018 Nov 1;102:449-457. doi: 10.1016/j.compbiomed.2018.07.011. Epub 2018 Jul 27.

PMID:
30316448
12.

Essential role of ryanodine receptor 2 phosphorylation in the effect of azumolene on ventricular arrhythmia vulnerability in a rabbit heart model.

Si D, Azam MA, Lai PFH, Zamiri N, Kichigina G, Asta J, Massé S, Bokhari MM, Porta-Sánchez A, Labos C, Sun H, Yang P, Nanthakumar K.

J Cardiovasc Electrophysiol. 2018 Dec;29(12):1707-1715. doi: 10.1111/jce.13737. Epub 2018 Oct 31.

PMID:
30203424
13.

Multicenter Study of Ischemic Ventricular Tachycardia Ablation With Decrement-Evoked Potential (DEEP) Mapping With Extra Stimulus.

Porta-Sánchez A, Jackson N, Lukac P, Kristiansen SB, Nielsen JM, Gizurarson S, Massé S, Labos C, Viswanathan K, King B, Ha ACT, Downar E, Nanthakumar K.

JACC Clin Electrophysiol. 2018 Mar;4(3):307-315. doi: 10.1016/j.jacep.2017.12.005. Epub 2018 Feb 3.

14.

Atrial decremental evoked potentials accurately determine the critical isthmus of intra-atrial re-entrant tachycardia.

Bhaskaran A, Gizurarson S, Porta-Sánchez A, Massé S, Nair K, Nanthakumar K.

Europace. 2018 Oct 1;20(10):1620. doi: 10.1093/europace/euy164. No abstract available.

PMID:
30085029
15.

KATP Channel Blockade as a Novel Antiarrhythmic Strategy: Evolving From Tachy to Brady Therapy.

Farid TA, Bhaskaran A, Nanthakumar K.

Endocrinology. 2018 Aug 1;159(8):3081-3082. doi: 10.1210/en.2018-00525. No abstract available.

PMID:
29955856
16.

Quantifying the determinants of decremental response in critical ventricular tachycardia substrate.

Beheshti M, Nayyar S, Magtibay K, Massé S, Porta-Sanchez A, Haldar S, Bhaskaran A, Vigmond E, Nanthakumar K.

Comput Biol Med. 2018 Nov 1;102:260-266. doi: 10.1016/j.compbiomed.2018.05.025. Epub 2018 May 28.

PMID:
29871758
17.

Twisting and Turning to Find an Explanation for Torsades de Pointes.

Nayyar S, Porta-Sánchez A, Nanthakumar K.

JACC Clin Electrophysiol. 2017 Dec 26;3(13):1577-1579. doi: 10.1016/j.jacep.2017.09.174. Epub 2017 Nov 6. No abstract available.

18.

Groin Haemostasis With a Purse String Suture for Patients Following Catheter Ablation Procedures (GITAR Study).

Jackson N, McGee M, Ahmed W, Davies A, Leitch J, Mills M, Cambourn M, Ezad S, Boyle A, Attia J, Nanthakumar K, Barlow M.

Heart Lung Circ. 2019 May;28(5):777-783. doi: 10.1016/j.hlc.2018.03.011. Epub 2018 Mar 20.

PMID:
29685719
19.

Heart rate in patients with reduced ejection fraction: relationship between single time point measurement and mean heart rate on prolonged implantable cardioverter defibrillator monitoring.

Habal MV, Nanthakumar K, Austin PC, Freitas C, Labos C, Lee DS.

BMC Cardiovasc Disord. 2018 Jan 31;18(1):17. doi: 10.1186/s12872-018-0751-2.

20.

Incidence, Diagnosis, and Management of QT Prolongation Induced by Cancer Therapies: A Systematic Review.

Porta-Sánchez A, Gilbert C, Spears D, Amir E, Chan J, Nanthakumar K, Thavendiranathan P.

J Am Heart Assoc. 2017 Dec 7;6(12). pii: e007724. doi: 10.1161/JAHA.117.007724. Review.

21.

Resolving Bipolar Electrogram Voltages During Atrial Fibrillation Using Omnipolar Mapping.

Haldar SK, Magtibay K, Porta-Sanchez A, Massé S, Mitsakakis N, Lai PFH, Azam MA, Asta J, Kusha M, Dorian P, Ha ACT, Chauhan V, Deno DC, Nanthakumar K.

Circ Arrhythm Electrophysiol. 2017 Sep;10(9). pii: e005018. doi: 10.1161/CIRCEP.117.005018.

PMID:
28887362
22.

Mortality Implications of Appropriate Implantable Cardioverter Defibrillator Therapy in Secondary Prevention Patients: Contrasting Mortality in Primary Prevention Patients From a Prospective Population-Based Registry.

Almehmadi F, Porta-Sánchez A, Ha ACT, Fischer HD, Wang X, Austin PC, Lee DS, Nanthakumar K.

J Am Heart Assoc. 2017 Aug 19;6(8). pii: e006220. doi: 10.1161/JAHA.117.006220.

23.

Physiological Assessment of Ventricular Myocardial Voltage Using Omnipolar Electrograms.

Magtibay K, Massé S, Asta J, Kusha M, Lai PFH, Azam MA, Porta-Sanchez A, Haldar S, Malebranche D, Labos C, Deno DC, Nanthakumar K.

J Am Heart Assoc. 2017 Aug 16;6(8). pii: e006447. doi: 10.1161/JAHA.117.006447.

24.

Effects of Late Sodium Current Blockade on Ventricular Refibrillation in a Rabbit Model.

Azam MA, Zamiri N, Massé S, Kusha M, Lai PF, Nair GK, Tan NS, Labos C, Nanthakumar K.

Circ Arrhythm Electrophysiol. 2017 Mar;10(3). pii: e004331. doi: 10.1161/CIRCEP.116.004331.

PMID:
28314848
25.

Effects of Renal Artery Denervation on Ventricular Arrhythmias in a Postinfarct Model.

Jackson N, Gizurarson S, Azam MA, King B, Ramadeen A, Zamiri N, Porta-Sánchez A, Al-Hesayen A, Graham J, Kusha M, Massé S, Lai PF, Parker J, John R, Kiehl TR, Nair GK, Dorian P, Nanthakumar K.

Circ Cardiovasc Interv. 2017 Mar;10(3):e004172. doi: 10.1161/CIRCINTERVENTIONS.116.004172.

PMID:
28258128
26.

The effect of left ventricular pacing on transmural activation delay in myopathic human hearts.

Porta-Sánchez A, Angaran P, Massé S, Nair K, Farid T, Umapathy K, Asta J, Gizurarson S, Nanthakumar K.

Europace. 2018 Apr 1;20(4):719-728. doi: 10.1093/europace/euw375.

27.

Effect of spatial resolution and filtering on mapping cardiac fibrillation.

King B, Porta-Sánchez A, Massé S, Zamiri N, Balasundaram K, Kusha M, Jackson N, Haldar S, Umapathy K, Nanthakumar K.

Heart Rhythm. 2017 Apr;14(4):608-615. doi: 10.1016/j.hrthm.2017.01.023. Epub 2017 Jan 17.

PMID:
28104480
28.

Orientation-Independent Catheter-Based Characterization of Myocardial Activation.

Deno DC, Balachandran R, Morgan D, Ahmad F, Masse S, Nanthakumar K.

IEEE Trans Biomed Eng. 2017 May;64(5):1067-1077. doi: 10.1109/TBME.2016.2589158. Epub 2016 Jul 7.

PMID:
27411215
29.

Resolving Myocardial Activation With Novel Omnipolar Electrograms.

Massé S, Magtibay K, Jackson N, Asta J, Kusha M, Zhang B, Balachandran R, Radisic M, Deno DC, Nanthakumar K.

Circ Arrhythm Electrophysiol. 2016 Jul;9(7):e004107. doi: 10.1161/CIRCEP.116.004107.

30.

Modeling Current Density Maps Using Aliev-Panfilov Electrophysiological Heart Model.

Beheshti M, Foomany FH, Magtibay K, Masse S, Lai P, Asta J, Jaffray DA, Nanthakumar K, Krishnan S, Umapathy K.

Cardiovasc Eng Technol. 2016 Sep;7(3):238-53. doi: 10.1007/s13239-016-0271-0. Epub 2016 Jun 29.

PMID:
27357301
31.

Feature-based MRI data fusion for cardiac arrhythmia studies.

Magtibay K, Beheshti M, Foomany FH, Massé S, Lai PF, Zamiri N, Asta J, Nanthakumar K, Jaffray D, Krishnan S, Umapathy K.

Comput Biol Med. 2016 May 1;72:13-21. doi: 10.1016/j.compbiomed.2016.02.006. Epub 2016 Feb 19.

PMID:
26970857
32.

Biodegradable scaffold with built-in vasculature for organ-on-a-chip engineering and direct surgical anastomosis.

Zhang B, Montgomery M, Chamberlain MD, Ogawa S, Korolj A, Pahnke A, Wells LA, Massé S, Kim J, Reis L, Momen A, Nunes SS, Wheeler AR, Nanthakumar K, Keller G, Sefton MV, Radisic M.

Nat Mater. 2016 Jun;15(6):669-78. doi: 10.1038/nmat4570. Epub 2016 Mar 7.

33.

The need for and the challenges of measuring renal sympathetic nerve activity.

Nair GKK, Massé S, Asta J, Sevaptisidis E, Azam MA, Lai PFH, Veluppillaim A, Magtibay K, Jackson N, Nanthakumar K.

Heart Rhythm. 2016 May;13(5):1166-1171. doi: 10.1016/j.hrthm.2016.01.018. Epub 2016 Jan 19. Review.

PMID:
26806582
34.

Decrement Evoked Potential Mapping: Basis of a Mechanistic Strategy for Ventricular Tachycardia Ablation.

Jackson N, Gizurarson S, Viswanathan K, King B, Massé S, Kusha M, Porta-Sanchez A, Jacob JR, Khan F, Das M, Ha AC, Pashaei A, Vigmond E, Downar E, Nanthakumar K.

Circ Arrhythm Electrophysiol. 2015 Dec;8(6):1433-42. doi: 10.1161/CIRCEP.115.003083. Epub 2015 Oct 19.

PMID:
26480929
35.

Feeding the fibrillating heart: Dichloroacetate improves cardiac contractile dysfunction following VF.

Azam MA, Wagg CS, Massé S, Farid T, Lai PF, Kusha M, Asta J, Jaimes R 3rd, Kuzmiak-Glancy S, Kay MW, Lopaschuk GD, Nanthakumar K.

Am J Physiol Heart Circ Physiol. 2015 Nov;309(9):H1543-53. doi: 10.1152/ajpheart.00404.2015. Epub 2015 Sep 4.

36.

Clinical Risk Stratification for Primary Prevention Implantable Cardioverter Defibrillators.

Lee DS, Hardy J, Yee R, Healey JS, Birnie D, Simpson CS, Crystal E, Mangat I, Nanthakumar K, Wang X, Krahn AD, Dorian P, Austin PC, Tu JV; Investigators of the Ontario ICD Database.

Circ Heart Fail. 2015 Sep;8(5):927-37. doi: 10.1161/CIRCHEARTFAILURE.115.002414. Epub 2015 Jul 29.

37.

Noise distribution and denoising of current density images.

Beheshti M, Foomany FH, Magtibay K, Jaffray DA, Krishnan S, Nanthakumar K, Umapathy K.

J Med Imaging (Bellingham). 2015 Apr;2(2):024005. doi: 10.1117/1.JMI.2.2.024005. Epub 2015 May 14.

38.

Mechanisms of Long-Duration Ventricular Fibrillation in Human Hearts and Experimental Validation in Canine Purkinje Fibers.

Jackson N, Massé S, Zamiri N, Azam MA, Lai PFH, Kusha M, Asta J, Quadros K, King B, Backx P, Ideker RE, Nanthakumar K.

JACC Clin Electrophysiol. 2015 Jun;1(3):187-197. doi: 10.1016/j.jacep.2015.04.003. Epub 2015 Apr 20.

39.

Temporal-component analysis of diastolic electrograms in ventricular tachycardia differentiates nonvulnerable regions of the circuit.

Das M, Downar E, Massé S, Harris L, Cameron D, Nair K, Chauhan VS, Spears DA, Ha AC, Jackson N, Nanthakumar K.

Heart Rhythm. 2015 Aug;12(8):1737-44. doi: 10.1016/j.hrthm.2015.05.004. Epub 2015 May 8.

PMID:
25962802
40.

Tracking rotors with minimal electrodes: modulation index-based strategy.

Balasundaram K, Umapathy K, Jeyaratnam J, Niri A, Massé S, Farid T, Nair K, Asta J, Cusimano RJ, Vigmond E, Nanthakumar K.

Circ Arrhythm Electrophysiol. 2015 Apr;8(2):447-55. doi: 10.1161/CIRCEP.114.002306. Epub 2015 Mar 4.

PMID:
25740825
41.

Increased atrial arrhythmia susceptibility induced by intense endurance exercise in mice requires TNFα.

Aschar-Sobbi R, Izaddoustdar F, Korogyi AS, Wang Q, Farman GP, Yang F, Yang W, Dorian D, Simpson JA, Tuomi JM, Jones DL, Nanthakumar K, Cox B, Wehrens XH, Dorian P, Backx PH.

Nat Commun. 2015 Jan 19;6:6018. doi: 10.1038/ncomms7018.

42.

Fusion of structural and functional cardiac magnetic resonance imaging data for studying ventricular fibrillation.

Magtibay K, Beheshti M, Foomany FH, Balasundaram K, Masse S, Lai P, Asta J, Zamiri N, Jaffray DA, Nanthakumar K, Krishnan S, Umapathy K.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:5579-82. doi: 10.1109/EMBC.2014.6944891.

PMID:
25571259
43.

A novel approach to quantification of real and artifactual components of current density imaging for phantom and live heart.

Foomany FH, Beheshti M, Magtibay K, Masse S, Lai P, Asta J, Zamiri N, Jaffray DA, Krishnan S, Nanthakumar K, Umapathy K.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:1075-8. doi: 10.1109/EMBC.2014.6943780.

PMID:
25570148
44.

The effects of long chain polyunsaturated fatty acids on local activation properties in dogs vulnerable to atrial fibrillation.

Abdulmajeed R, Ramadeen A, Masse S, Foomany FH, Balasundaram K, Hu X, Nanthakumar K, Dorian P, Umapathy K.

Conf Proc IEEE Eng Med Biol Soc. 2014;2014:1067-70. doi: 10.1109/EMBC.2014.6943778.

PMID:
25570146
45.

TMEM43 mutation p.S358L alters intercalated disc protein expression and reduces conduction velocity in arrhythmogenic right ventricular cardiomyopathy.

Siragam V, Cui X, Masse S, Ackerley C, Aafaqi S, Strandberg L, Tropak M, Fridman MD, Nanthakumar K, Liu J, Sun Y, Su B, Wang C, Liu X, Yan Y, Mendlowitz A, Hamilton RM.

PLoS One. 2014 Oct 24;9(10):e109128. doi: 10.1371/journal.pone.0109128. eCollection 2014.

46.

Bipolar ablation for deep intra-myocardial circuits: human ex vivo development and in vivo experience.

Gizurarson S, Spears D, Sivagangabalan G, Farid T, Ha AC, Massé S, Kusha M, Chauhan VS, Nair K, Harris L, Downar E, Nanthakumar K.

Europace. 2014 Nov;16(11):1684-8. doi: 10.1093/europace/euu001. Epub 2014 Feb 19.

PMID:
24554525
47.

Mechanism of reentry induction by a 9-V battery in rabbit ventricles.

Bishop MJ, Burton RA, Kalla M, Nanthakumar K, Plank G, Bub G, Vigmond EJ.

Am J Physiol Heart Circ Physiol. 2014 Apr 1;306(7):H1041-53. doi: 10.1152/ajpheart.00591.2013. Epub 2014 Jan 24.

48.

Regional ion channel gene expression heterogeneity and ventricular fibrillation dynamics in human hearts.

Sivagangabalan G, Nazzari H, Bignolais O, Maguy A, Naud P, Farid T, Massé S, Gaborit N, Varro A, Nair K, Backx P, Vigmond E, Nattel S, Demolombe S, Nanthakumar K.

PLoS One. 2014 Jan 10;9(1):e82179. doi: 10.1371/journal.pone.0082179. eCollection 2014.

49.

Dantrolene improves survival after ventricular fibrillation by mitigating impaired calcium handling in animal models.

Zamiri N, Massé S, Ramadeen A, Kusha M, Hu X, Azam MA, Liu J, Lai PF, Vigmond EJ, Boyle PM, Behradfar E, Al-Hesayen A, Waxman MB, Backx P, Dorian P, Nanthakumar K.

Circulation. 2014 Feb 25;129(8):875-85. doi: 10.1161/CIRCULATIONAHA.113.005443. Epub 2014 Jan 8.

PMID:
24403563
50.

Design and formulation of functional pluripotent stem cell-derived cardiac microtissues.

Thavandiran N, Dubois N, Mikryukov A, Massé S, Beca B, Simmons CA, Deshpande VS, McGarry JP, Chen CS, Nanthakumar K, Keller GM, Radisic M, Zandstra PW.

Proc Natl Acad Sci U S A. 2013 Dec 3;110(49):E4698-707. doi: 10.1073/pnas.1311120110. Epub 2013 Nov 19. Erratum in: Proc Natl Acad Sci U S A. 2014 Nov 25;111(47):16973. Proc Natl Acad Sci U S A. 2015 Jun 16;112(24):E3151.

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