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Items: 10

1.

Discovery of the selective androgen receptor modulator MK-0773 using a rational development strategy based on differential transcriptional requirements for androgenic anabolism versus reproductive physiology.

Schmidt A, Kimmel DB, Bai C, Scafonas A, Rutledge S, Vogel RL, McElwee-Witmer S, Chen F, Nantermet PV, Kasparcova V, Leu CT, Zhang HZ, Duggan ME, Gentile MA, Hodor P, Pennypacker B, Masarachia P, Opas EE, Adamski SA, Cusick TE, Wang J, Mitchell HJ, Kim Y, Prueksaritanont T, Perkins JJ, Meissner RS, Hartman GD, Freedman LP, Harada S, Ray WJ.

J Biol Chem. 2010 May 28;285(22):17054-64. doi: 10.1074/jbc.M109.099002. Epub 2010 Mar 31.

2.

Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands.

Schmidt A, Harada S, Kimmel DB, Bai C, Chen F, Rutledge SJ, Vogel RL, Scafonas A, Gentile MA, Nantermet PV, McElwee-Witmer S, Pennypacker B, Masarachia P, Sahoo SP, Kim Y, Meissner RS, Hartman GD, Duggan ME, Rodan GA, Towler DA, Ray WJ.

J Biol Chem. 2009 Dec 25;284(52):36367-76. doi: 10.1074/jbc.M109.049734. Epub 2009 Oct 21.

3.

Androgen-mediated improvement of body composition and muscle function involves a novel early transcriptional program including IGF1, mechano growth factor, and induction of {beta}-catenin.

Gentile MA, Nantermet PV, Vogel RL, Phillips R, Holder D, Hodor P, Cheng C, Dai H, Freedman LP, Ray WJ.

J Mol Endocrinol. 2010 Jan;44(1):55-73. doi: 10.1677/JME-09-0048. Epub 2009 Sep 2.

PMID:
19726620
4.

Control of rat tail skin temperature regulation by estrogen receptor-beta selective ligand.

Opas EE, Scafonas A, Nantermet PV, Wilkening RR, Birzin ET, Wilkinson H, Colwell LF, Schaeffer JM, Towler DA, Rodan GA, Schmidt A.

Maturitas. 2009 Sep 20;64(1):46-51. doi: 10.1016/j.maturitas.2009.07.007. Epub 2009 Aug 12.

PMID:
19679413
5.

A regulatory circuit mediating convergence between Nurr1 transcriptional regulation and Wnt signaling.

Kitagawa H, Ray WJ, Glantschnig H, Nantermet PV, Yu Y, Leu CT, Harada S, Kato S, Freedman LP.

Mol Cell Biol. 2007 Nov;27(21):7486-96. Epub 2007 Aug 20. Retraction in: Mol Cell Biol. 2014 Mar;34(5):917.

6.

Androgenic induction of growth and differentiation in the rodent uterus involves the modulation of estrogen-regulated genetic pathways.

Nantermet PV, Masarachia P, Gentile MA, Pennypacker B, Xu J, Holder D, Gerhold D, Towler D, Schmidt A, Kimmel DB, Freedman LP, Harada S, Ray WJ.

Endocrinology. 2005 Feb;146(2):564-78. Epub 2004 Oct 21.

PMID:
15498879
7.

Identification of genetic pathways activated by the androgen receptor during the induction of proliferation in the ventral prostate gland.

Nantermet PV, Xu J, Yu Y, Hodor P, Holder D, Adamski S, Gentile MA, Kimmel DB, Harada S, Gerhold D, Freedman LP, Ray WJ.

J Biol Chem. 2004 Jan 9;279(2):1310-22. Epub 2003 Oct 23.

8.

The p2 domain of human immunodeficiency virus type 1 Gag regulates sequential proteolytic processing and is required to produce fully infectious virions.

Pettit SC, Moody MD, Wehbie RS, Kaplan AH, Nantermet PV, Klein CA, Swanstrom R.

J Virol. 1994 Dec;68(12):8017-27.

9.

Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo.

Shugars DC, Smith MS, Glueck DH, Nantermet PV, Seillier-Moiseiwitsch F, Swanstrom R.

J Virol. 1993 Aug;67(8):4639-50. Erratum in: J Virol 1994 Aug;68(8):5335.

10.

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