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Items: 22

1.

A Biliary Tract-Specific Near-Infrared Fluorescent Dye for Image-Guided Hepatobiliary Surgery.

Luciano MP, Namgoong JM, Nani RR, Nam SH, Lee C, Shin IH, Schnermann MJ, Cha J.

Mol Pharm. 2019 Jul 1;16(7):3253-3260. doi: 10.1021/acs.molpharmaceut.9b00453. Epub 2019 Jun 21.

PMID:
31244218
2.

A Nonaggregating Heptamethine Cyanine for Building Brighter Labeled Biomolecules.

Luciano MP, Crooke SN, Nourian S, Dingle I, Nani RR, Kline G, Patel NL, Robinson CM, Difilippantonio S, Kalen JD, Finn MG, Schnermann MJ.

ACS Chem Biol. 2019 May 17;14(5):934-940. doi: 10.1021/acschembio.9b00122. Epub 2019 Apr 27.

3.

Harnessing Cyanine Reactivity for Optical Imaging and Drug Delivery.

Gorka AP, Nani RR, Schnermann MJ.

Acc Chem Res. 2018 Dec 18;51(12):3226-3235. doi: 10.1021/acs.accounts.8b00384. Epub 2018 Nov 12.

PMID:
30418020
4.

Glypican-3-Specific Antibody Drug Conjugates Targeting Hepatocellular Carcinoma.

Fu Y, Urban DJ, Nani RR, Zhang YF, Li N, Fu H, Shah H, Gorka AP, Guha R, Chen L, Hall MD, Schnermann MJ, Ho M.

Hepatology. 2019 Aug;70(2):563-576. doi: 10.1002/hep.30326. Epub 2019 Feb 19.

PMID:
30353932
5.

A chemically stable fluorescent marker of the ureter.

Cha J, Nani RR, Luciano MP, Kline G, Broch A, Kim K, Namgoong JM, Kulkarni RA, Meier JL, Kim P, Schnermann MJ.

Bioorg Med Chem Lett. 2018 Sep 1;28(16):2741-2745. doi: 10.1016/j.bmcl.2018.02.040. Epub 2018 Feb 24.

6.

Molecularly Targeted Cancer Combination Therapy with Near-Infrared Photoimmunotherapy and Near-Infrared Photorelease with Duocarmycin-Antibody Conjugate.

Nagaya T, Gorka AP, Nani RR, Okuyama S, Ogata F, Maruoka Y, Choyke PL, Schnermann MJ, Kobayashi H.

Mol Cancer Ther. 2018 Mar;17(3):661-670. doi: 10.1158/1535-7163.MCT-17-0851. Epub 2017 Dec 13.

7.

In Vivo Activation of Duocarmycin-Antibody Conjugates by Near-Infrared Light.

Nani RR, Gorka AP, Nagaya T, Yamamoto T, Ivanic J, Kobayashi H, Schnermann MJ.

ACS Cent Sci. 2017 Apr 26;3(4):329-337. doi: 10.1021/acscentsci.7b00026. Epub 2017 Feb 24.

8.

Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular Scaffold.

Chan ST, Nani RR, Schauer EA, Martin GE, Williamson RT, Saurí J, Buevich AV, Schafer WA, Joyce LA, Goey AK, Figg WD, Ransom TT, Henrich CJ, McKee TC, Moser A, MacDonald SA, Khan S, McMahon JB, Schnermann MJ, Gustafson KR.

J Org Chem. 2016 Nov 18;81(22):10631-10640. Epub 2016 Nov 10.

9.

Effect of charge localization on the in vivo optical imaging properties of near-infrared cyanine dye/monoclonal antibody conjugates.

Sato K, Gorka AP, Nagaya T, Michie MS, Nakamura Y, Nani RR, Coble VL, Vasalatiy OV, Swenson RE, Choyke PL, Schnermann MJ, Kobayashi H.

Mol Biosyst. 2016 Oct 20;12(10):3046-56. doi: 10.1039/c6mb00371k. Epub 2016 Jul 25.

10.

Effect of Metalation on Porphyrin-Based Bifunctional Agents in Tumor Imaging and Photodynamic Therapy.

Patel NJ, Chen Y, Joshi P, Pera P, Baumann H, Missert JR, Ohkubo K, Fukuzumi S, Nani RR, Schnermann MJ, Chen P, Zhu J, Kadish KM, Pandey RK.

Bioconjug Chem. 2016 Mar 16;27(3):667-80. doi: 10.1021/acs.bioconjchem.5b00656. Epub 2016 Jan 21.

PMID:
26735143
11.

Reactive Species Involved in the Regioselective Photooxidation of Heptamethine Cyanines.

Nani RR, Kelley JA, Ivanic J, Schnermann MJ.

Chem Sci. 2015 Nov 1;6(11):6556-6563. Epub 2015 Aug 18.

12.

Role of Fluorophore Charge on the In Vivo Optical Imaging Properties of Near-Infrared Cyanine Dye/Monoclonal Antibody Conjugates.

Sato K, Gorka AP, Nagaya T, Michie MS, Nani RR, Nakamura Y, Coble VL, Vasalatiy OV, Swenson RE, Choyke PL, Schnermann MJ, Kobayashi H.

Bioconjug Chem. 2016 Feb 17;27(2):404-13. doi: 10.1021/acs.bioconjchem.5b00492. Epub 2015 Oct 23.

PMID:
26444497
13.

Near-IR Light-Mediated Cleavage of Antibody-Drug Conjugates Using Cyanine Photocages.

Nani RR, Gorka AP, Nagaya T, Kobayashi H, Schnermann MJ.

Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13635-8. doi: 10.1002/anie.201507391. Epub 2015 Sep 25.

14.

Impact of C4'-O-Alkyl Linker on in Vivo Pharmacokinetics of Near-Infrared Cyanine/Monoclonal Antibody Conjugates.

Sato K, Nagaya T, Nakamura Y, Harada T, Nani RR, Shaum JB, Gorka AP, Kim I, Paik CH, Choyke PL, Schnermann MJ, Kobayashi H.

Mol Pharm. 2015 Sep 8;12(9):3303-11. doi: 10.1021/acs.molpharmaceut.5b00472. Epub 2015 Aug 18.

15.

Impact of Substituents in Tumor Uptake and Fluorescence Imaging Ability of Near-Infrared Cyanine-like Dyes.

Patel NJ, Manivannan E, Joshi P, Ohulchanskyy TJ, Nani RR, Schnermann MJ, Pandey RK.

Photochem Photobiol. 2015 Sep-Oct;91(5):1219-30. doi: 10.1111/php.12482. Epub 2015 Jul 30.

16.

A cationic cysteine-hydrazide as an enrichment tool for the mass spectrometric characterization of bacterial free oligosaccharides.

Jang KS, Nani RR, Kalli A, Levin S, Müller A, Hess S, Reisman SE, Clemons WM Jr.

Anal Bioanal Chem. 2015 Aug;407(20):6181-90. doi: 10.1007/s00216-015-8798-8. Epub 2015 Jun 23.

17.

Cyanine polyene reactivity: scope and biomedical applications.

Gorka AP, Nani RR, Schnermann MJ.

Org Biomol Chem. 2015 Jul 28;13(28):7584-98. doi: 10.1039/c5ob00788g. Review.

PMID:
26052876
18.

Electrophile-integrating Smiles rearrangement provides previously inaccessible C4'-O-alkyl heptamethine cyanine fluorophores.

Nani RR, Shaum JB, Gorka AP, Schnermann MJ.

Org Lett. 2015 Jan 16;17(2):302-5. doi: 10.1021/ol503398f. Epub 2015 Jan 6.

19.

A near-IR uncaging strategy based on cyanine photochemistry.

Gorka AP, Nani RR, Zhu J, Mackem S, Schnermann MJ.

J Am Chem Soc. 2014 Oct 8;136(40):14153-9. doi: 10.1021/ja5065203. Epub 2014 Sep 24.

20.

α-Diazo-β-ketonitriles: uniquely reactive substrates for arene and alkene cyclopropanation.

Nani RR, Reisman SE.

J Am Chem Soc. 2013 May 15;135(19):7304-11. doi: 10.1021/ja401610p. Epub 2013 May 3.

PMID:
23642221
21.

Enantioselective total synthesis of (+)-salvileucalin B.

Levin S, Nani RR, Reisman SE.

J Am Chem Soc. 2011 Feb 2;133(4):774-6. doi: 10.1021/ja110192b.

PMID:
21174417
22.

Rapid assembly of the salvileucalin B norcaradiene core.

Levin S, Nani RR, Reisman SE.

Org Lett. 2010 Feb 19;12(4):780-3. doi: 10.1021/ol902848k.

PMID:
20088588

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