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Items: 20

1.

AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment.

Kalra R, Bhagyaraj E, Tiwari D, Nanduri R, Chacko AP, Jain M, Mahajan S, Khatri N, Gupta P.

Oncogenesis. 2018 May 25;7(5):43. doi: 10.1038/s41389-018-0053-7.

2.

A human xenobiotic nuclear receptor contributes to nonresponsiveness of Mycobacterium tuberculosis to the antituberculosis drug rifampicin.

Bhagyaraj E, Tiwari D, Ahuja N, Nanduri R, Saini A, Kalra R, Kumar S, Janmeja AK, Gupta P.

J Biol Chem. 2018 Mar 9;293(10):3747-3757. doi: 10.1074/jbc.M117.818377. Epub 2018 Jan 22.

PMID:
29358328
3.

Discovery of Imidazo[1,2-a]pyridine Ethers and Squaramides as Selective and Potent Inhibitors of Mycobacterial Adenosine Triphosphate (ATP) Synthesis.

Tantry SJ, Markad SD, Shinde V, Bhat J, Balakrishnan G, Gupta AK, Ambady A, Raichurkar A, Kedari C, Sharma S, Mudugal NV, Narayan A, Naveen Kumar CN, Nanduri R, Bharath S, Reddy J, Panduga V, Prabhakar KR, Kandaswamy K, Saralaya R, Kaur P, Dinesh N, Guptha S, Rich K, Murray D, Plant H, Preston M, Ashton H, Plant D, Walsh J, Alcock P, Naylor K, Collier M, Whiteaker J, McLaughlin RE, Mallya M, Panda M, Rudrapatna S, Ramachandran V, Shandil R, Sambandamurthy VK, Mdluli K, Cooper CB, Rubin H, Yano T, Iyer P, Narayanan S, Kavanagh S, Mukherjee K, Balasubramanian V, Hosagrahara VP, Solapure S, Ravishankar S, Hameed P S.

J Med Chem. 2017 Feb 23;60(4):1379-1399. doi: 10.1021/acs.jmedchem.6b01358. Epub 2017 Feb 3.

PMID:
28075132
4.

Human Xenobiotic Nuclear Receptor PXR Augments Mycobacterium tuberculosis Survival.

Bhagyaraj E, Nanduri R, Saini A, Dkhar HK, Ahuja N, Chandra V, Mahajan S, Kalra R, Tiwari D, Sharma C, Janmeja AK, Gupta P.

J Immunol. 2016 Jul 1;197(1):244-55. doi: 10.4049/jimmunol.1600203. Epub 2016 May 27.

5.

ONRLDB--manually curated database of experimentally validated ligands for orphan nuclear receptors: insights into new drug discovery.

Nanduri R, Bhutani I, Somavarapu AK, Mahajan S, Parkesh R, Gupta P.

Database (Oxford). 2015 Dec 4;2015. pii: bav112. doi: 10.1093/database/bav112. Print 2015.

6.

NR1D1 ameliorates Mycobacterium tuberculosis clearance through regulation of autophagy.

Chandra V, Bhagyaraj E, Nanduri R, Ahuja N, Gupta P.

Autophagy. 2015 Nov 2;11(11):1987-1997.

7.

In silico-based high-throughput screen for discovery of novel combinations for tuberculosis treatment.

Singh R, Ramachandran V, Shandil R, Sharma S, Khandelwal S, Karmarkar M, Kumar N, Solapure S, Saralaya R, Nanduri R, Panduga V, Reddy J, Prabhakar KR, Rajagopalan S, Rao N, Narayanan S, Anandkumar A, Balasubramanian V, Datta S.

Antimicrob Agents Chemother. 2015 Sep;59(9):5664-74. doi: 10.1128/AAC.05148-14. Epub 2015 Jul 6.

8.

Nuclear Receptor Nr4a2 Promotes Alternative Polarization of Macrophages and Confers Protection in Sepsis.

Mahajan S, Saini A, Chandra V, Nanduri R, Kalra R, Bhagyaraj E, Khatri N, Gupta P.

J Biol Chem. 2015 Jul 24;290(30):18304-14. doi: 10.1074/jbc.M115.638064. Epub 2015 May 7.

9.

Oleic acid complex of bovine α-lactalbumin induces eryptosis in human and other erythrocytes by a Ca(2+)-independent mechanism.

Hoque M, Nanduri R, Gupta J, Mahajan S, Gupta P, Saleemuddin M.

Biochim Biophys Acta. 2015 Sep;1850(9):1729-39. doi: 10.1016/j.bbagen.2015.04.009. Epub 2015 Apr 23.

PMID:
25913522
10.
11.

N-aryl-2-aminobenzimidazoles: novel, efficacious, antimalarial lead compounds.

Ramachandran S, Hameed P S, Srivastava A, Shanbhag G, Morayya S, Rautela N, Awasthy D, Kavanagh S, Bharath S, Reddy J, Panduga V, Prabhakar KR, Saralaya R, Nanduri R, Raichurkar A, Menasinakai S, Achar V, Jiménez-Díaz MB, Martínez MS, Angulo-Barturen I, Ferrer S, Sanz LM, Gamo FJ, Duffy S, Avery VM, Waterson D, Lee MC, Coburn-Flynn O, Fidock DA, Iyer PS, Narayanan S, Hosagrahara V, Sambandamurthy VK.

J Med Chem. 2014 Aug 14;57(15):6642-52. doi: 10.1021/jm500715u. Epub 2014 Jul 21.

PMID:
25007124
12.

Nuclear MEK1 sequesters PPARγ and bisects MEK1/ERK signaling: a non-canonical pathway of retinoic acid inhibition of adipocyte differentiation.

Dave S, Nanduri R, Dkhar HK, Bhagyaraj E, Rao A, Gupta P.

PLoS One. 2014 Jun 24;9(6):e100862. doi: 10.1371/journal.pone.0100862. eCollection 2014.

13.

Mycobacterium tuberculosis keto-mycolic acid and macrophage nuclear receptor TR4 modulate foamy biogenesis in granulomas: a case of a heterologous and noncanonical ligand-receptor pair.

Dkhar HK, Nanduri R, Mahajan S, Dave S, Saini A, Somavarapu AK, Arora A, Parkesh R, Thakur KG, Mayilraj S, Gupta P.

J Immunol. 2014 Jul 1;193(1):295-305. doi: 10.4049/jimmunol.1400092. Epub 2014 Jun 6.

14.

Lead optimization of 1,4-azaindoles as antimycobacterial agents.

Shirude PS, Shandil RK, Manjunatha MR, Sadler C, Panda M, Panduga V, Reddy J, Saralaya R, Nanduri R, Ambady A, Ravishankar S, Sambandamurthy VK, Humnabadkar V, Jena LK, Suresh RS, Srivastava A, Prabhakar KR, Whiteaker J, McLaughlin RE, Sharma S, Cooper CB, Mdluli K, Butler S, Iyer PS, Narayanan S, Chatterji M.

J Med Chem. 2014 Jul 10;57(13):5728-37. doi: 10.1021/jm500571f. Epub 2014 Jun 20.

PMID:
24874895
15.

Human IL10 gene repression by Rev-erbα ameliorates Mycobacterium tuberculosis clearance.

Chandra V, Mahajan S, Saini A, Dkhar HK, Nanduri R, Raj EB, Kumar A, Gupta P.

J Biol Chem. 2013 Apr 12;288(15):10692-702. doi: 10.1074/jbc.M113.455915. Epub 2013 Feb 28.

16.

Stem bromelain-induced macrophage apoptosis and activation curtail Mycobacterium tuberculosis persistence.

Mahajan S, Chandra V, Dave S, Nanduri R, Gupta P.

J Infect Dis. 2012 Aug 1;206(3):366-76. doi: 10.1093/infdis/jis354. Epub 2012 May 21.

PMID:
22615313
17.

Mycobacterium tuberculosis modulates macrophage lipid-sensing nuclear receptors PPARγ and TR4 for survival.

Mahajan S, Dkhar HK, Chandra V, Dave S, Nanduri R, Janmeja AK, Agrewala JN, Gupta P.

J Immunol. 2012 Jun 1;188(11):5593-603. doi: 10.4049/jimmunol.1103038. Epub 2012 Apr 27.

18.

Inhibition of adipogenesis and induction of apoptosis and lipolysis by stem bromelain in 3T3-L1 adipocytes.

Dave S, Kaur NJ, Nanduri R, Dkhar HK, Kumar A, Gupta P.

PLoS One. 2012;7(1):e30831. doi: 10.1371/journal.pone.0030831. Epub 2012 Jan 24.

19.

Cellular mechanisms associated with intermittent hypoxia.

Nanduri J, Nanduri RP.

Essays Biochem. 2007;43:91-104. Review.

PMID:
17705795
20.

Laceration of the stomach by blunt trauma in a child: a case of child abuse.

Case ME, Nanduri R.

J Forensic Sci. 1983 Apr;28(2):496-501.

PMID:
6864189

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