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Items: 29

1.

Opposite Roles of MerTK Ligands Gas6 and Protein S During Retinal Phagocytosis.

Nandrot EF.

Adv Exp Med Biol. 2018;1074:577-583. doi: 10.1007/978-3-319-75402-4_70.

PMID:
29721990
2.

Chronic exposure to tumor necrosis factor alpha induces retinal pigment epithelium cell dedifferentiation.

Touhami S, Beguier F, Augustin S, Charles-Messance H, Vignaud L, Nandrot EF, Reichman S, Forster V, Mathis T, Sahel JA, Bodaghi B, Guillonneau X, Sennlaub F.

J Neuroinflammation. 2018 Mar 16;15(1):85. doi: 10.1186/s12974-018-1106-8.

3.

Otx2-Genetically Modified Retinal Pigment Epithelial Cells Rescue Photoreceptors after Transplantation.

Kole C, Klipfel L, Yang Y, Ferracane V, Blond F, Reichman S, Millet-Puel G, Clérin E, Aït-Ali N, Pagan D, Camara H, Delyfer MN, Nandrot EF, Sahel JA, Goureau O, Léveillard T.

Mol Ther. 2018 Jan 3;26(1):219-237. doi: 10.1016/j.ymthe.2017.09.007. Epub 2017 Sep 8.

4.

Collectin-11 Is an Important Modulator of Retinal Pigment Epithelial Cell Phagocytosis and Cytokine Production.

Dong X, Wu W, Ma L, Liu C, Bhuckory MB, Wang L, Nandrot EF, Xu H, Li K, Liu Y, Zhou W.

J Innate Immun. 2017;9(6):529-545. doi: 10.1159/000478042. Epub 2017 Aug 4.

5.

Generation of Storable Retinal Organoids and Retinal Pigmented Epithelium from Adherent Human iPS Cells in Xeno-Free and Feeder-Free Conditions.

Reichman S, Slembrouck A, Gagliardi G, Chaffiol A, Terray A, Nanteau C, Potey A, Belle M, Rabesandratana O, Duebel J, Orieux G, Nandrot EF, Sahel JA, Goureau O.

Stem Cells. 2017 May;35(5):1176-1188. doi: 10.1002/stem.2586. Epub 2017 Feb 20.

6.

A Comprehensive Review of Mutations in the MERTK Proto-Oncogene.

Parinot C, Nandrot EF.

Adv Exp Med Biol. 2016;854:259-65. doi: 10.1007/978-3-319-17121-0_35. Review.

PMID:
26427420
7.

Large-scale purification of porcine or bovine photoreceptor outer segments for phagocytosis assays on retinal pigment epithelial cells.

Parinot C, Rieu Q, Chatagnon J, Finnemann SC, Nandrot EF.

J Vis Exp. 2014 Dec 12;(94). doi: 10.3791/52100.

8.

Cleavage of Mer tyrosine kinase (MerTK) from the cell surface contributes to the regulation of retinal phagocytosis.

Law AL, Parinot C, Chatagnon J, Gravez B, Sahel JA, Bhattacharya SS, Nandrot EF.

J Biol Chem. 2015 Feb 20;290(8):4941-52. doi: 10.1074/jbc.M114.628297. Epub 2014 Dec 23.

9.

Mutations in pre-mRNA processing factors 3, 8, and 31 cause dysfunction of the retinal pigment epithelium.

Farkas MH, Lew DS, Sousa ME, Bujakowska K, Chatagnon J, Bhattacharya SS, Pierce EA, Nandrot EF.

Am J Pathol. 2014 Oct;184(10):2641-52. doi: 10.1016/j.ajpath.2014.06.026. Epub 2014 Aug 8.

10.

From confluent human iPS cells to self-forming neural retina and retinal pigmented epithelium.

Reichman S, Terray A, Slembrouck A, Nanteau C, Orieux G, Habeler W, Nandrot EF, Sahel JA, Monville C, Goureau O.

Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):8518-23. doi: 10.1073/pnas.1324212111. Epub 2014 May 27.

11.

Animal Models, in "The Quest to Decipher RPE Phagocytosis".

Nandrot EF.

Adv Exp Med Biol. 2014;801:77-83. doi: 10.1007/978-1-4614-3209-8_10. Review.

PMID:
24664683
12.

Disease-causing mutations in BEST1 gene are associated with altered sorting of bestrophin-1 protein.

Doumanov JA, Zeitz C, Dominguez Gimenez P, Audo I, Krishna A, Alfano G, Diaz ML, Moskova-Doumanova V, Lancelot ME, Sahel JA, Nandrot EF, Bhattacharya SS.

Int J Mol Sci. 2013 Jul 22;14(7):15121-40. doi: 10.3390/ijms140715121.

13.

Human induced pluripotent stem cells as a tool to model a form of Leber congenital amaurosis.

Lustremant C, Habeler W, Plancheron A, Goureau O, Grenot L, de la Grange P, Audo I, Nandrot EF, Monville C.

Cell Reprogram. 2013 Jun;15(3):233-46. doi: 10.1089/cell.2012.0076. Epub 2013 May 10.

PMID:
23663011
14.

Retinal pigment epithelial cells use a MerTK-dependent mechanism to limit the phagocytic particle binding activity of αvβ5 integrin.

Nandrot EF, Silva KE, Scelfo C, Finnemann SC.

Biol Cell. 2012 Jun;104(6):326-41. doi: 10.1111/boc.201100076. Epub 2012 Mar 5.

15.

The Signalling Role of the avβ5-Integrin Can Impact the Efficacy of AAV in Retinal Gene Therapy.

Cronin T, Chung DC, Yang Y, Nandrot EF, Bennett J.

Pharmaceuticals (Basel). 2012 May 2;5(5):447-59. doi: 10.3390/ph5050447.

16.

On your marks…get bound…internalize!

Law AL, Nandrot EF.

Adv Exp Med Biol. 2012;723:717-22. doi: 10.1007/978-1-4614-0631-0_91. Review. No abstract available.

PMID:
22183398
17.

Dietary antioxidants prevent age-related retinal pigment epithelium actin damage and blindness in mice lacking αvβ5 integrin.

Yu CC, Nandrot EF, Dun Y, Finnemann SC.

Free Radic Biol Med. 2012 Feb 1;52(3):660-670. doi: 10.1016/j.freeradbiomed.2011.11.021. Epub 2011 Dec 8.

18.

In vitro differentiation of retinal pigment epithelium from adult retinal stem cells.

Aruta C, Giordano F, De Marzo A, Comitato A, Raposo G, Nandrot EF, Marigo V.

Pigment Cell Melanoma Res. 2011 Feb;24(1):233-40. doi: 10.1111/j.1755-148X.2010.00793.x. Epub 2010 Nov 10.

PMID:
21232026
19.

Three gene-targeted mouse models of RNA splicing factor RP show late-onset RPE and retinal degeneration.

Graziotto JJ, Farkas MH, Bujakowska K, Deramaudt BM, Zhang Q, Nandrot EF, Inglehearn CF, Bhattacharya SS, Pierce EA.

Invest Ophthalmol Vis Sci. 2011 Jan 5;52(1):190-8. doi: 10.1167/iovs.10-5194. Print 2011 Jan.

20.

EYS is a major gene for rod-cone dystrophies in France.

Audo I, Sahel JA, Mohand-Saïd S, Lancelot ME, Antonio A, Moskova-Doumanova V, Nandrot EF, Doumanov J, Barragan I, Antinolo G, Bhattacharya SS, Zeitz C.

Hum Mutat. 2010 May;31(5):E1406-35. doi: 10.1002/humu.21249.

PMID:
20333770
21.

Mertk in daily retinal phagocytosis: a history in the making.

Nandrot EF, Dufour EM.

Adv Exp Med Biol. 2010;664:133-40. doi: 10.1007/978-1-4419-1399-9_16.

PMID:
20238011
22.

TRPM1 is mutated in patients with autosomal-recessive complete congenital stationary night blindness.

Audo I, Kohl S, Leroy BP, Munier FL, Guillonneau X, Mohand-Saïd S, Bujakowska K, Nandrot EF, Lorenz B, Preising M, Kellner U, Renner AB, Bernd A, Antonio A, Moskova-Doumanova V, Lancelot ME, Poloschek CM, Drumare I, Defoort-Dhellemmes S, Wissinger B, Léveillard T, Hamel CP, Schorderet DF, De Baere E, Berger W, Jacobson SG, Zrenner E, Sahel JA, Bhattacharya SS, Zeitz C.

Am J Hum Genet. 2009 Nov;85(5):720-9. doi: 10.1016/j.ajhg.2009.10.013. Epub 2009 Nov 5.

23.

Lack of alphavbeta5 integrin receptor or its ligand MFG-E8: distinct effects on retinal function.

Nandrot EF, Finnemann SC.

Ophthalmic Res. 2008;40(3-4):120-3. doi: 10.1159/000119861. Epub 2008 Apr 18.

24.

Alphavbeta5 integrin receptors at the apical surface of the RPE: one receptor, two functions.

Nandrot EF, Chang Y, Finnemann SC.

Adv Exp Med Biol. 2008;613:369-75. doi: 10.1007/978-0-387-74904-4_43. Review. No abstract available.

25.

Essential role for MFG-E8 as ligand for alphavbeta5 integrin in diurnal retinal phagocytosis.

Nandrot EF, Anand M, Almeida D, Atabai K, Sheppard D, Finnemann SC.

Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12005-10. Epub 2007 Jul 9.

26.

MerTK activation during RPE phagocytosis in vivo requires alphaVbeta5 integrin.

Finnemann SC, Nandrot EF.

Adv Exp Med Biol. 2006;572:499-503. No abstract available.

27.

Altered rhythm of photoreceptor outer segment phagocytosis in beta5 integrin knockout mice.

Nandrot EF, Finnemann SC.

Adv Exp Med Biol. 2006;572:119-23. No abstract available.

28.

Novel role for alphavbeta5-integrin in retinal adhesion and its diurnal peak.

Nandrot EF, Anand M, Sircar M, Finnemann SC.

Am J Physiol Cell Physiol. 2006 Apr;290(4):C1256-62. Epub 2005 Dec 7.

29.

Loss of synchronized retinal phagocytosis and age-related blindness in mice lacking alphavbeta5 integrin.

Nandrot EF, Kim Y, Brodie SE, Huang X, Sheppard D, Finnemann SC.

J Exp Med. 2004 Dec 20;200(12):1539-45. Epub 2004 Dec 13.

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