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Items: 28


Improved Swiss-rolling Technique for Intestinal Tissue Preparation for Immunohistochemical and Immunofluorescent Analyses.

Bialkowska AB, Ghaleb AM, Nandan MO, Yang VW.

J Vis Exp. 2016 Jul 13;(113). doi: 10.3791/54161.


Role of Krüppel-like factor 5 in the maintenance of the stem cell niche in the intestinal crypt.

Kuruvilla JG, Ghaleb AM, Bialkowska AB, Nandan MO, Yang VW.

Stem Cell Transl Investig. 2015;2(2). pii: e839.


Krüppel-like factor 6 regulates mitochondrial function in the kidney.

Mallipattu SK, Horne SJ, D'Agati V, Narla G, Liu R, Frohman MA, Dickman K, Chen EY, Ma'ayan A, Bialkowska AB, Ghaleb AM, Nandan MO, Jain MK, Daehn I, Chuang PY, Yang VW, He JC.

J Clin Invest. 2015 Mar 2;125(3):1347-61. doi: 10.1172/JCI77084. Epub 2015 Feb 17.


Krüppel-like factor 5 is essential for proliferation and survival of mouse intestinal epithelial stem cells.

Nandan MO, Ghaleb AM, Bialkowska AB, Yang VW.

Stem Cell Res. 2015 Jan;14(1):10-9. doi: 10.1016/j.scr.2014.10.008. Epub 2014 Nov 6.


Krüppel-like factor 4 is a radioprotective factor for the intestine following γ-radiation-induced gut injury in mice.

Talmasov D, Xinjun Z, Yu B, Nandan MO, Bialkowska AB, Elkarim E, Kuruvilla J, Yang VW, Ghaleb AM.

Am J Physiol Gastrointest Liver Physiol. 2015 Jan 15;308(2):G121-38. doi: 10.1152/ajpgi.00080.2014. Epub 2014 Nov 20.


Inducible intestine-specific deletion of Krüppel-like factor 5 is characterized by a regenerative response in adult mouse colon.

Nandan MO, Ghaleb AM, Liu Y, Bialkowska AB, McConnell BB, Shroyer KR, Robine S, Yang VW.

Dev Biol. 2014 Mar 15;387(2):191-202. doi: 10.1016/j.ydbio.2014.01.002. Epub 2014 Jan 15.


The E3 ubiquitin ligase SMAD ubiquitination regulatory factor 2 negatively regulates Krüppel-like factor 5 protein.

Du JX, Hagos EG, Nandan MO, Bialkowska AB, Yu B, Yang VW.

J Biol Chem. 2011 Nov 18;286(46):40354-64. doi: 10.1074/jbc.M111.258707. Epub 2011 Sep 27.


An Update on the Biology of RAS/RAF Mutations in Colorectal Cancer.

Nandan MO, Yang VW.

Curr Colorectal Cancer Rep. 2011 Jun 1;7(2):113-120.


Expression of the tumor suppressor Krüppel-like factor 4 as a prognostic predictor for colon cancer.

Patel NV, Ghaleb AM, Nandan MO, Yang VW.

Cancer Epidemiol Biomarkers Prev. 2010 Oct;19(10):2631-8. doi: 10.1158/1055-9965.EPI-10-0677. Epub 2010 Aug 10.


Genetic and Chemical Models of Colorectal Cancer in Mice.

Nandan MO, Yang VW.

Curr Colorectal Cancer Rep. 2010 Mar 10;6(2):51-59.


Krüppel-like factor 5 is a crucial mediator of intestinal tumorigenesis in mice harboring combined ApcMin and KRASV12 mutations.

Nandan MO, Ghaleb AM, McConnell BB, Patel NV, Robine S, Yang VW.

Mol Cancer. 2010 Mar 18;9:63. doi: 10.1186/1476-4598-9-63.


The role of Krüppel-like factors in the reprogramming of somatic cells to induced pluripotent stem cells.

Nandan MO, Yang VW.

Histol Histopathol. 2009 Oct;24(10):1343-55. doi: 10.14670/HH-24.1343. Review.


Haploinsufficiency of Krüppel-like factor 5 rescues the tumor-initiating effect of the Apc(Min) mutation in the intestine.

McConnell BB, Bialkowska AB, Nandan MO, Ghaleb AM, Gordon FJ, Yang VW.

Cancer Res. 2009 May 15;69(10):4125-33. doi: 10.1158/0008-5472.CAN-08-4402. Epub 2009 May 12.


Notch inhibits expression of the Krüppel-like factor 4 tumor suppressor in the intestinal epithelium.

Ghaleb AM, Aggarwal G, Bialkowska AB, Nandan MO, Yang VW.

Mol Cancer Res. 2008 Dec;6(12):1920-7. doi: 10.1158/1541-7786.MCR-08-0224.


Krüppel-like factor 5 mediates transmissible murine colonic hyperplasia caused by Citrobacter rodentium infection.

McConnell BB, Klapproth JM, Sasaki M, Nandan MO, Yang VW.

Gastroenterology. 2008 Apr;134(4):1007-16. doi: 10.1053/j.gastro.2008.01.013. Epub 2008 Jan 11.


Human cancer cells commonly acquire DNA damage during mitotic arrest.

Dalton WB, Nandan MO, Moore RT, Yang VW.

Cancer Res. 2007 Dec 15;67(24):11487-92.


Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis.

Nandan MO, McConnell BB, Ghaleb AM, Bialkowska AB, Sheng H, Shao J, Babbin BA, Robine S, Yang VW.

Gastroenterology. 2008 Jan;134(1):120-30. Epub 2007 Oct 17.


Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis.

Ghaleb AM, McConnell BB, Nandan MO, Katz JP, Kaestner KH, Yang VW.

Cancer Res. 2007 Aug 1;67(15):7147-54.


The diverse functions of Krüppel-like factors 4 and 5 in epithelial biology and pathobiology.

McConnell BB, Ghaleb AM, Nandan MO, Yang VW.

Bioessays. 2007 Jun;29(6):549-57. Review. Erratum in: Bioessays. 2007 Sep;29(9):946.


Kruppel-like factor 5 is an important mediator for lipopolysaccharide-induced proinflammatory response in intestinal epithelial cells.

Chanchevalap S, Nandan MO, McConnell BB, Charrier L, Merlin D, Katz JP, Yang VW.

Nucleic Acids Res. 2006 Feb 25;34(4):1216-23. Print 2006.


Krüppel-like factor 4 prevents centrosome amplification following gamma-irradiation-induced DNA damage.

Yoon HS, Ghaleb AM, Nandan MO, Hisamuddin IM, Dalton WB, Yang VW.

Oncogene. 2005 Jun 9;24(25):4017-25.


Krüppel-like factors 4 and 5: the yin and yang regulators of cellular proliferation.

Ghaleb AM, Nandan MO, Chanchevalap S, Dalton WB, Hisamuddin IM, Yang VW.

Cell Res. 2005 Feb;15(2):92-6. Review.


Krüppel-like factor 5 mediates the transforming activity of oncogenic H-Ras.

Nandan MO, Yoon HS, Zhao W, Ouko LA, Chanchevalap S, Yang VW.

Oncogene. 2004 Apr 22;23(19):3404-13.


Identification of Krüppel-like factor 4 as a potential tumor suppressor gene in colorectal cancer.

Zhao W, Hisamuddin IM, Nandan MO, Babbin BA, Lamb NE, Yang VW.

Oncogene. 2004 Jan 15;23(2):395-402.

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