Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 131

1.

Asperosaponin VI protects against bone destructions in collagen induced arthritis by inhibiting osteoclastogenesis.

Liu K, Liu Y, Xu Y, Nandakumar KS, Tan H, He C, Dang W, Lin J, Zhou C.

Phytomedicine. 2019 Jul 2;63:153006. doi: 10.1016/j.phymed.2019.153006. [Epub ahead of print]

PMID:
31299594
2.

SNX10 (sorting nexin 10) inhibits colorectal cancer initiation and progression by controlling autophagic degradation of SRC.

Zhang S, Yang Z, Bao W, Liu L, You Y, Wang X, Shao L, Fu W, Kou X, Shen W, Yuan C, Hu B, Dang W, Nandakumar KS, Jiang H, Zheng M, Shen X.

Autophagy. 2019 Jul 4:1-15. doi: 10.1080/15548627.2019.1632122. [Epub ahead of print]

PMID:
31208298
3.

Cartilage-binding antibodies induce pain through immune complex-mediated activation of neurons.

Bersellini Farinotti A, Wigerblad G, Nascimento D, Bas DB, Morado Urbina C, Nandakumar KS, Sandor K, Xu B, Abdelmoaty S, Hunt MA, Ängeby Möller K, Baharpoor A, Sinclair J, Jardemark K, Lanner JT, Khmaladze I, Borm LE, Zhang L, Wermeling F, Cragg MS, Lengqvist J, Chabot-Doré AJ, Diatchenko L, Belfer I, Collin M, Kultima K, Heyman B, Jimenez-Andrade JM, Codeluppi S, Holmdahl R, Svensson CI.

J Exp Med. 2019 Aug 5;216(8):1904-1924. doi: 10.1084/jem.20181657. Epub 2019 Jun 13.

PMID:
31196979
4.

Autophagy induced by STING, an unnoticed and primordial function of cGAS.

Yang J, Tang X, Nandakumar KS, Cheng K.

Cell Mol Immunol. 2019 Aug;16(8):683-684. doi: 10.1038/s41423-019-0240-2. Epub 2019 May 29. No abstract available.

PMID:
31142798
5.

TLR1/2 Specific Small-Molecule Agonist Suppresses Leukemia Cancer Cell Growth by Stimulating Cytotoxic T Lymphocytes.

Cen X, Zhu G, Yang J, Yang J, Guo J, Jin J, Nandakumar KS, Yang W, Yin H, Liu S, Cheng K.

Adv Sci (Weinh). 2019 Mar 27;6(10):1802042. doi: 10.1002/advs.201802042. eCollection 2019 May 17.

6.

Therapeutic effects of artesunate on lupus-prone MRL/lpr mice are dependent on T follicular helper cell differentiation and activation of JAK2-STAT3 signaling pathway.

Dang WZ, Li H, Jiang B, Nandakumar KS, Liu KF, Liu LX, Yu XC, Tan HJ, Zhou C.

Phytomedicine. 2019 May 19;62:152965. doi: 10.1016/j.phymed.2019.152965. [Epub ahead of print]

PMID:
31129432
7.

Analysis of Data From Breast Diseases Treated With 5-Alpha Reductase Inhibitors for Benign Prostatic Hyperplasia.

Fang Q, Chen P, Du N, Nandakumar KS.

Clin Breast Cancer. 2019 Apr 18. pii: S1526-8209(18)30837-1. doi: 10.1016/j.clbc.2019.04.006. [Epub ahead of print] Review.

PMID:
31126837
8.

Regulatory role of Golgi brefeldin A resistance factor-1 in amyloid precursor protein trafficking, cleavage and Aβ formation.

Liu K, Liu Y, Xu Y, Nandakumar KS, Shen X, Lin J, Li C, He C, Zhou C.

J Cell Biochem. 2019 Sep;120(9):15604-15615. doi: 10.1002/jcb.28827. Epub 2019 May 20.

PMID:
31111546
9.

Protective effects of Wang-Bi tablet on bone destruction in collagen-induced arthritis by regulating osteoclast-osteoblast functions.

Shen W, Guan YY, Wu RM, Liu LX, Li HD, Bao WL, Zhang Y, Nandakumar KS, Ye G, Shen X.

J Ethnopharmacol. 2019 Jun 28;238:111861. doi: 10.1016/j.jep.2019.111861. Epub 2019 Apr 4.

PMID:
30954617
10.

The autoantibody response to cyclic citrullinated collagen type II peptides in rheumatoid arthritis.

Liang B, Ge C, Lönnblom E, Lin X, Feng H, Xiao L, Bai J, Ayoglu B, Nilsson P, Nandakumar KS, Zhao M, Holmdahl R.

Rheumatology (Oxford). 2019 Sep 1;58(9):1623-1633. doi: 10.1093/rheumatology/kez073.

PMID:
30892636
11.

Q63, a novel DENV2 RdRp non-nucleoside inhibitor, inhibited DENV2 replication and infection.

Yao X, Guo S, Wu W, Wang J, Wu S, He S, Wan Y, Nandakumar KS, Chen X, Sun N, Zhu Q, Liu S.

J Pharmacol Sci. 2018 Dec;138(4):247-256. doi: 10.1016/j.jphs.2018.06.012. Epub 2018 Jun 25.

12.

Streptococcal Endo-β-N-Acetylglucosaminidase Suppresses Antibody-Mediated Inflammation In Vivo.

Nandakumar KS, Collin M, Happonen KE, Lundström SL, Croxford AM, Xu B, Zubarev RA, Rowley MJ, Blom AM, Kjellman C, Holmdahl R.

Front Immunol. 2018 Jul 16;9:1623. doi: 10.3389/fimmu.2018.01623. eCollection 2018.

13.

A Shared Epitope of Collagen Type XI and Type II Is Recognized by Pathogenic Antibodies in Mice and Humans with Arthritis.

Tong D, Lönnblom E, Yau ACY, Nandakumar KS, Liang B, Ge C, Viljanen J, Li L, Bãlan M, Klareskog L, Chagin AS, Gjertsson I, Kihlberg J, Zhao M, Holmdahl R.

Front Immunol. 2018 Apr 12;9:451. doi: 10.3389/fimmu.2018.00451. eCollection 2018.

14.

Recent advances in the development of vaccines for chronic inflammatory autoimmune diseases.

Zhang N, Nandakumar KS.

Vaccine. 2018 May 31;36(23):3208-3220. doi: 10.1016/j.vaccine.2018.04.062. Epub 2018 Apr 26. Review.

PMID:
29706295
15.

Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections.

Yao X, Ling Y, Guo S, Wu W, He S, Zhang Q, Zou M, Nandakumar KS, Chen X, Liu S.

Phytomedicine. 2018 Mar 15;42:258-267. doi: 10.1016/j.phymed.2018.03.018. Epub 2018 Mar 15.

PMID:
29655694
16.

Antigen-Specific Tolerization and Targeted Delivery as Therapeutic Strategies for Autoimmune Diseases.

Shakya AK, Nandakumar KS.

Trends Biotechnol. 2018 Jul;36(7):686-699. doi: 10.1016/j.tibtech.2018.02.008. Epub 2018 Mar 24. Review.

PMID:
29588069
17.

A Restricted Role for FcγR in the Regulation of Adaptive Immunity.

Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS.

J Immunol. 2018 Apr 15;200(8):2615-2626. doi: 10.4049/jimmunol.1700429. Epub 2018 Mar 9.

18.

Chronic Active Arthritis Driven by Macrophages Without Involvement of T Cells: A Novel Experimental Model of Rheumatoid Arthritis.

Hagert C, Sareila O, Kelkka T, Nandakumar KS, Collin M, Xu B, Guérard S, Bäcklund J, Jalkanen S, Holmdahl R.

Arthritis Rheumatol. 2018 Aug;70(8):1343-1353. doi: 10.1002/art.40482. Epub 2018 Jun 20.

19.

Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T-cell-associated autoimmunity.

Vaartjes D, Nandakumar KS, Holmdahl R, Raposo B.

Immunology. 2018 Mar 7. doi: 10.1111/imm.12923. [Epub ahead of print]

20.

Targeting IgG in Arthritis: Disease Pathways and Therapeutic Avenues.

Nandakumar KS.

Int J Mol Sci. 2018 Feb 28;19(3). pii: E677. doi: 10.3390/ijms19030677. Review.

21.

An update on smart biocatalysts for industrial and biomedical applications.

Shakya AK, Nandakumar KS.

J R Soc Interface. 2018 Feb;15(139). pii: 20180062. doi: 10.1098/rsif.2018.0062. Review.

22.

Targeting pattern-recognition receptors to discover new small molecule immune modulators.

Zhu G, Xu Y, Cen X, Nandakumar KS, Liu S, Cheng K.

Eur J Med Chem. 2018 Jan 20;144:82-92. doi: 10.1016/j.ejmech.2017.12.026. Epub 2017 Dec 8. Review.

PMID:
29268133
23.

Inhibition of dengue viral infection by diasarone-I is associated with 2'O methyltransferase of NS5.

Yao X, Ling Y, Guo S, He S, Wang J, Zhang Q, Wu W, Zou M, Zhang T, Nandakumar KS, Chen X, Liu S.

Eur J Pharmacol. 2018 Feb 15;821:11-20. doi: 10.1016/j.ejphar.2017.12.029. Epub 2017 Dec 13.

PMID:
29246851
24.

Germinal Center B Cells Are Essential for Collagen-Induced Arthritis.

Dahdah A, Habir K, Nandakumar KS, Saxena A, Xu B, Holmdahl R, Malin S.

Arthritis Rheumatol. 2018 Feb;70(2):193-203. doi: 10.1002/art.40354. Epub 2018 Jan 22.

25.

Regulation of autoantibody activity by the IL-23-TH17 axis determines the onset of autoimmune disease.

Pfeifle R, Rothe T, Ipseiz N, Scherer HU, Culemann S, Harre U, Ackermann JA, Seefried M, Kleyer A, Uderhardt S, Haugg B, Hueber AJ, Daum P, Heidkamp GF, Ge C, Böhm S, Lux A, Schuh W, Magorivska I, Nandakumar KS, Lönnblom E, Becker C, Dudziak D, Wuhrer M, Rombouts Y, Koeleman CA, Toes R, Winkler TH, Holmdahl R, Herrmann M, Blüml S, Nimmerjahn F, Schett G, Krönke G.

Nat Immunol. 2017 Jan;18(1):104-113. doi: 10.1038/ni.3579. Epub 2016 Nov 7.

26.

Animal Models of Rheumatoid Arthritis (I): Pristane-Induced Arthritis in the Rat.

Tuncel J, Haag S, Hoffmann MH, Yau AC, Hultqvist M, Olofsson P, Bäcklund J, Nandakumar KS, Weidner D, Fischer A, Leichsenring A, Lange F, Haase C, Lu S, Gulko PS, Steiner G, Holmdahl R.

PLoS One. 2016 May 26;11(5):e0155936. doi: 10.1371/journal.pone.0155936. eCollection 2016.

27.

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.

Wigerblad G, Bas DB, Fernades-Cerqueira C, Krishnamurthy A, Nandakumar KS, Rogoz K, Kato J, Sandor K, Su J, Jimenez-Andrade JM, Finn A, Bersellini Farinotti A, Amara K, Lundberg K, Holmdahl R, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Svensson CI.

Ann Rheum Dis. 2016 Apr;75(4):730-8. doi: 10.1136/annrheumdis-2015-208094. Epub 2015 Nov 27. Erratum in: Ann Rheum Dis. 2019 Jun;78(6):865.

28.

Macrophage-derived reactive oxygen species protects against autoimmune priming with a defined polymeric adjuvant.

Shakya AK, Kumar A, Holmdahl R, Nandakumar KS.

Immunology. 2016 Jan;147(1):125-32. doi: 10.1111/imm.12546. Epub 2015 Nov 24.

29.

System A amino acid transporters regulate glutamine uptake and attenuate antibody-mediated arthritis.

Raposo B, Vaartjes D, Ahlqvist E, Nandakumar KS, Holmdahl R.

Immunology. 2015 Dec;146(4):607-17. doi: 10.1111/imm.12531. Epub 2015 Oct 5.

30.

B-cell epitope spreading and inflammation in a mouse model of arthritis is associated with a deficiency in reactive oxygen species production.

Khmaladze Ia, Saxena A, Nandakumar KS, Holmdahl R.

Eur J Immunol. 2015 Aug;45(8):2243-51. doi: 10.1002/eji.201545518. Epub 2015 Jun 3.

31.

Reactive oxygen species in psoriasis and psoriasis arthritis: relevance to human disease.

Khmaladze Ia, Nandakumar KS, Holmdahl R.

Int Arch Allergy Immunol. 2015;166(2):135-49. doi: 10.1159/000375401. Epub 2015 Mar 20. Review.

32.

Synthetic polymer as an adjuvant in collagen-induced arthritis.

Shakya AK, Nandakumar KS.

Curr Protoc Mouse Biol. 2014 Mar 21;4(1):11-24. doi: 10.1002/9780470942390.mo130226.

PMID:
25715674
33.

Mannan induces ROS-regulated, IL-17A-dependent psoriasis arthritis-like disease in mice.

Khmaladze Ia, Kelkka T, Guerard S, Wing K, Pizzolla A, Saxena A, Lundqvist K, Holmdahl M, Nandakumar KS, Holmdahl R.

Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3669-78. doi: 10.1073/pnas.1405798111. Epub 2014 Aug 18.

34.

Nerve conduction velocity is regulated by the inositol polyphosphate-4-phosphatase II gene.

Lemcke S, Müller S, Möller S, Schillert A, Ziegler A, Cepok-Kauffeld S, Comabella M, Montalban X, Rülicke T, Nandakumar KS, Hemmer B, Holmdahl R, Pahnke J, Ibrahim SM.

Am J Pathol. 2014 Sep;184(9):2420-9. doi: 10.1016/j.ajpath.2014.05.021. Epub 2014 Aug 13.

PMID:
25129256
35.

Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.

Ossipova E, Cerqueira CF, Reed E, Kharlamova N, Israelsson L, Holmdahl R, Nandakumar KS, Engström M, Harre U, Schett G, Catrina AI, Malmström V, Sommarin Y, Klareskog L, Jakobsson PJ, Lundberg K.

Arthritis Res Ther. 2014 Aug 12;16(4):R167. doi: 10.1186/ar4683.

36.

Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice.

Lindh I, Snir O, Lönnblom E, Uysal H, Andersson I, Nandakumar KS, Vierboom M, 't Hart B, Malmström V, Holmdahl R.

Arthritis Res Ther. 2014 Jul 8;16(4):R143. doi: 10.1186/ar4605.

37.

The basics and advances of immunomodulators and antigen presentation: a key to development of potent memory response against pathogens.

Garai P, Gogoi M, Gopal G, Radhakrishnan Y, Nandakumar KS, Chakravortty D.

Expert Opin Biol Ther. 2014 Oct;14(10):1383-97. doi: 10.1517/14712598.2014.925871. Epub 2014 Jun 4. Review.

PMID:
24897303
38.

A single functional group substitution in c5a breaks B cell and T cell tolerance and protects against experimental arthritis.

Kessel C, Nandakumar KS, Peters FB, Gauba V, Schultz PG, Holmdahl R.

Arthritis Rheumatol. 2014 Mar;66(3):610-21. doi: 10.1002/art.38237.

39.

Epitope-specific antibody response is controlled by immunoglobulin V(H) polymorphisms.

Raposo B, Dobritzsch D, Ge C, Ekman D, Xu B, Lindh I, Förster M, Uysal H, Nandakumar KS, Schneider G, Holmdahl R.

J Exp Med. 2014 Mar 10;211(3):405-11. doi: 10.1084/jem.20130968. Epub 2014 Feb 17.

40.

Polymeric cryogels are biocompatible, and their biodegradation is independent of oxidative radicals.

Shakya AK, Holmdahl R, Nandakumar KS, Kumar A.

J Biomed Mater Res A. 2014 Oct;102(10):3409-18. doi: 10.1002/jbm.a.35013. Epub 2013 Oct 28.

PMID:
24142798
41.

Incomplete B cell tolerance to cartilage oligomeric matrix protein in mice.

Geng H, Nandakumar KS, Xiong L, Jie R, Dong J, Holmdahl R.

Arthritis Rheum. 2013 Sep;65(9):2301-9. doi: 10.1002/art.38046.

42.

Characterization of chemically defined poly-N-isopropylacrylamide based copolymeric adjuvants.

Shakya AK, Holmdahl R, Nandakumar KS, Kumar A.

Vaccine. 2013 Aug 2;31(35):3519-27. doi: 10.1016/j.vaccine.2013.05.084. Epub 2013 Jun 4.

PMID:
23742996
43.

Dominant suppression of inflammation by glycan-hydrolyzed IgG.

Nandakumar KS, Collin M, Happonen KE, Croxford AM, Lundström SL, Zubarev RA, Rowley MJ, Blom AM, Holmdahl R.

Proc Natl Acad Sci U S A. 2013 Jun 18;110(25):10252-7. doi: 10.1073/pnas.1301480110. Epub 2013 May 13. Retraction in: Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):15851.

44.

Type II collagen-specific antibodies induce cartilage damage in mice independent of inflammation.

Croxford AM, Whittingham S, McNaughton D, Nandakumar KS, Holmdahl R, Rowley MJ.

Arthritis Rheum. 2013 Mar;65(3):650-9. doi: 10.1002/art.37805.

45.

Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases.

Shakya AK, Nandakumar KS.

J R Soc Interface. 2013 Feb;10(79):20120536. doi: 10.1098/rsif.2012.0536. Review.

46.

C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells.

Bäcklund J, Li C, Jansson E, Carlsen S, Merky P, Nandakumar KS, Haag S, Ytterberg J, Zubarev RA, Holmdahl R.

Ann Rheum Dis. 2013 Jul;72(7):1225-32. doi: 10.1136/annrheumdis-2012-202055. Epub 2012 Oct 5.

PMID:
23041839
47.

Liv.52 up-regulates cellular antioxidants and increase glucose uptake to circumvent oleic acid induced hepatic steatosis in HepG2 cells.

Vidyashankar S, Sharath Kumar LM, Barooah V, Sandeep Varma R, Nandakumar KS, Patki PS.

Phytomedicine. 2012 Oct 15;19(13):1156-65. doi: 10.1016/j.phymed.2012.08.005. Epub 2012 Aug 30.

PMID:
22940028
48.

Collagen antibody-induced arthritis evokes persistent pain with spinal glial involvement and transient prostaglandin dependency.

Bas DB, Su J, Sandor K, Agalave NM, Lundberg J, Codeluppi S, Baharpoor A, Nandakumar KS, Holmdahl R, Svensson CI.

Arthritis Rheum. 2012 Dec;64(12):3886-96. doi: 10.1002/art.37686.

49.

Cartilage oligomeric matrix protein specific antibodies are pathogenic.

Geng H, Nandakumar KS, Pramhed A, Aspberg A, Mattsson R, Holmdahl R.

Arthritis Res Ther. 2012 Aug 20;14(4):R191. doi: 10.1186/ar4022.

50.

Genetic control of antibody production during collagen-induced arthritis development in heterogeneous stock mice.

Förster M, Raposo B, Ekman D, Klaczkowska D, Popovic M, Nandakumar KS, Lindvall T, Hultqvist M, Teneva I, Johannesson M, Ahlqvist E, Holmdahl R.

Arthritis Rheum. 2012 Nov;64(11):3594-603. doi: 10.1002/art.34658.

Supplemental Content

Loading ...
Support Center