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Items: 46

1.

The role of Nav1.7 in human nociceptors: insights from human induced pluripotent stem cell-derived sensory neurons of erythromelalgia patients.

Meents JE, Bressan E, Sontag S, Foerster A, Hautvast P, Rösseler C, Hampl M, Schüler H, Goetzke R, Le TKC, Kleggetveit IP, Le Cann K, Kerth C, Rush AM, Rogers M, Kohl Z, Schmelz M, Wagner W, Jørum E, Namer B, Winner B, Zenke M, Lampert A.

Pain. 2019 Jun;160(6):1327-1341. doi: 10.1097/j.pain.0000000000001511.

PMID:
30720580
2.

Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors.

Namer B, Schmidt D, Eberhardt E, Maroni M, Dorfmeister E, Kleggetveit IP, Kaluza L, Meents J, Gerlach A, Lin Z, Winterpacht A, Dragicevic E, Kohl Z, Schüttler J, Kurth I, Warncke T, Jorum E, Winner B, Lampert A.

EBioMedicine. 2019 Jan;39:401-408. doi: 10.1016/j.ebiom.2018.11.042. Epub 2018 Nov 28.

3.

Etomidate and propylene glycol activate nociceptive TRP ion channels.

Niedermirtl F, Eberhardt M, Namer B, Leffler A, Nau C, Reeh PW, Kistner K.

Mol Pain. 2018 Jan-Dec;14:1744806918811699. doi: 10.1177/1744806918811699. Epub 2018 Oct 22.

PMID:
30345869
4.

Cyclic changes in sensations to painful stimuli in migraine patients.

Strupf M, Fraunberger B, Messlinger K, Namer B.

Cephalalgia. 2019 Apr;39(5):585-596. doi: 10.1177/0333102418793641. Epub 2018 Aug 12.

PMID:
30099953
5.

Cross-over evaluation of electrically induced pain and hyperalgesia.

Dusch M, Namer B, Strupf M, Schley M, Rukwied R, Hägglöf B, Schmelz M, Koppert W.

Scand J Pain. 2010 Oct 1;1(4):205-210. doi: 10.1016/j.sjpain.2010.08.002.

PMID:
29913991
6.

Tuning in C-nociceptors to reveal mechanisms in chronic neuropathic pain.

Jonas R, Namer B, Stockinger L, Chisholm K, Schnakenberg M, Landmann G, Kucharczyk M, Konrad C, Schmidt R, Carr R, McMahon S, Schmelz M, Rukwied R.

Ann Neurol. 2018 May;83(5):945-957. doi: 10.1002/ana.25231. Epub 2018 May 11.

PMID:
29659054
7.

Low-Frequency Stimulation of Silent Nociceptors Induces Secondary Mechanical Hyperalgesia in Human Skin.

Sauerstein K, Liebelt J, Namer B, Schmidt R, Rukwied R, Schmelz M.

Neuroscience. 2018 Sep 1;387:4-12. doi: 10.1016/j.neuroscience.2018.03.006. Epub 2018 Mar 15.

PMID:
29551562
8.

Nerve growth factor locally sensitizes nociceptors in human skin.

Obreja O, Rukwied R, Nagler L, Schmidt M, Schmelz M, Namer B.

Pain. 2018 Mar;159(3):416-426. doi: 10.1097/j.pain.0000000000001108.

PMID:
29140928
9.

Testing a linear time invariant model for skin conductance responses by intraneural recording and stimulation.

Gerster S, Namer B, Elam M, Bach DR.

Psychophysiology. 2018 Feb;55(2). doi: 10.1111/psyp.12986. Epub 2017 Sep 1.

10.

Changes in Ionic Conductance Signature of Nociceptive Neurons Underlying Fabry Disease Phenotype.

Namer B, Ørstavik K, Schmidt R, Mair N, Kleggetveit IP, Zeidler M, Martha T, Jorum E, Schmelz M, Kalpachidou T, Kress M, Langeslag M.

Front Neurol. 2017 Jul 14;8:335. doi: 10.3389/fneur.2017.00335. eCollection 2017.

11.

TRPA1 and TRPV1 Antagonists Do Not Inhibit Human Acidosis-Induced Pain.

Schwarz MG, Namer B, Reeh PW, Fischer MJM.

J Pain. 2017 May;18(5):526-534. doi: 10.1016/j.jpain.2016.12.011. Epub 2017 Jan 3.

PMID:
28062311
12.

Pathological nociceptors in two patients with erythromelalgia-like symptoms and rare genetic Nav 1.9 variants.

Kleggetveit IP, Schmidt R, Namer B, Salter H, Helås T, Schmelz M, Jørum E.

Brain Behav. 2016 Jul 21;6(10):e00528. eCollection 2016 Oct.

13.

SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing.

Kist AM, Sagafos D, Rush AM, Neacsu C, Eberhardt E, Schmidt R, Lunden LK, Ørstavik K, Kaluza L, Meents J, Zhang Z, Carr TH, Salter H, Malinowsky D, Wollberg P, Krupp J, Kleggetveit IP, Schmelz M, Jørum E, Lampert A, Namer B.

PLoS One. 2016 Sep 6;11(9):e0161789. doi: 10.1371/journal.pone.0161789. eCollection 2016.

14.

Single-Fiber Recordings of Nociceptive Fibers in Patients With HSAN Type V With Congenital Insensitivity to Pain.

Sagafos D, Kleggetveit IP, Helås T, Schmidt R, Minde J, Namer B, Schmelz M, Jørum E.

Clin J Pain. 2016 Jul;32(7):636-42. doi: 10.1097/AJP.0000000000000303.

PMID:
27270876
15.

Photosensitization in Porphyrias and Photodynamic Therapy Involves TRPA1 and TRPV1.

Babes A, Sauer SK, Moparthi L, Kichko TI, Neacsu C, Namer B, Filipovic M, Zygmunt PM, Reeh PW, Fischer MJ.

J Neurosci. 2016 May 11;36(19):5264-78. doi: 10.1523/JNEUROSCI.4268-15.2016.

16.

Automated detection of latency tracks in microneurography recordings using track correlation.

Turnquist B, RichardWebster B, Namer B.

J Neurosci Methods. 2016 Mar 15;262:133-41. doi: 10.1016/j.jneumeth.2016.01.004. Epub 2016 Jan 8.

PMID:
26778609
17.

Pathogenesis and Management of Pruritus in PBC and PSC.

Kremer AE, Namer B, Bolier R, Fischer MJ, Oude Elferink RP, Beuers U.

Dig Dis. 2015;33 Suppl 2:164-75. doi: 10.1159/000440829. Epub 2015 Dec 7. Review.

PMID:
26641452
18.

Pattern of Functional TTX-Resistant Sodium Channels Reveals a Developmental Stage of Human iPSC- and ESC-Derived Nociceptors.

Eberhardt E, Havlicek S, Schmidt D, Link AS, Neacsu C, Kohl Z, Hampl M, Kist AM, Klinger A, Nau C, Schüttler J, Alzheimer C, Winkler J, Namer B, Winner B, Lampert A.

Stem Cell Reports. 2015 Sep 8;5(3):305-13. doi: 10.1016/j.stemcr.2015.07.010. Epub 2015 Aug 28.

19.

Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7.

Namer B, Ørstavik K, Schmidt R, Kleggetveit IP, Weidner C, Mørk C, Kvernebo MS, Kvernebo K, Salter H, Carr TH, Segerdahl M, Quiding H, Waxman SG, Handwerker HO, Torebjörk HE, Jørum E, Schmelz M.

Pain. 2015 Sep;156(9):1637-46. doi: 10.1097/j.pain.0000000000000229.

PMID:
25993546
20.

C-fiber recovery cycle supernormality depends on ion concentration and ion channel permeability.

Tigerholm J, Petersson ME, Obreja O, Eberhardt E, Namer B, Weidner C, Lampert A, Carr RW, Schmelz M, Fransén E.

Biophys J. 2015 Mar 10;108(5):1057-71. doi: 10.1016/j.bpj.2014.12.034.

21.

H2S and NO cooperatively regulate vascular tone by activating a neuroendocrine HNO-TRPA1-CGRP signalling pathway.

Eberhardt M, Dux M, Namer B, Miljkovic J, Cordasic N, Will C, Kichko TI, de la Roche J, Fischer M, Suárez SA, Bikiel D, Dorsch K, Leffler A, Babes A, Lampert A, Lennerz JK, Jacobi J, Martí MA, Doctorovich F, Högestätt ED, Zygmunt PM, Ivanovic-Burmazovic I, Messlinger K, Reeh P, Filipovic MR.

Nat Commun. 2014 Jul 15;5:4381. doi: 10.1038/ncomms5381.

22.

Differential sensitization of silent nociceptors to low pH stimulation by prostaglandin E2 in human volunteers.

Namer B, Schick M, Kleggetveit IP, Ørstavik K, Schmidt R, Jorum E, Torebjörk E, Handwerker H, Schmelz M.

Eur J Pain. 2015 Feb;19(2):159-66. doi: 10.1002/ejp.532. Epub 2014 May 30.

PMID:
24890616
23.
24.

Analgesic treatment of ciguatoxin-induced cold allodynia.

Zimmermann K, Deuis JR, Inserra MC, Collins LS, Namer B, Cabot PJ, Reeh PW, Lewis RJ, Vetter I.

Pain. 2013 Oct;154(10):1999-2006. doi: 10.1016/j.pain.2013.06.015. Epub 2013 Jun 15.

PMID:
23778293
25.

Scratching an itch.

Namer B, Reeh P.

Nat Neurosci. 2013 Feb;16(2):117-8. doi: 10.1038/nn.3316. No abstract available.

PMID:
23354383
26.

Differential effects of low dose lidocaine on C-fiber classes in humans.

Kankel J, Obreja O, Kleggetveit IP, Schmidt R, Jørum E, Schmelz M, Namer B.

J Pain. 2012 Dec;13(12):1232-41. doi: 10.1016/j.jpain.2012.09.008.

PMID:
23182228
27.

Axon reflex flare and quantitative sudomotor axon reflex contribute in the diagnosis of small fiber neuropathy.

Namer B, Pfeffer S, Handwerker HO, Schmelz M, Bickel A.

Muscle Nerve. 2013 Mar;47(3):357-63. doi: 10.1002/mus.23543. Epub 2012 Nov 24.

PMID:
23180613
28.

High spontaneous activity of C-nociceptors in painful polyneuropathy.

Kleggetveit IP, Namer B, Schmidt R, Helås T, Rückel M, Ørstavik K, Schmelz M, Jørum E.

Pain. 2012 Oct;153(10):2040-7. doi: 10.1016/j.pain.2012.05.017.

PMID:
22986070
29.

Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons.

Klinger AB, Eberhardt M, Link AS, Namer B, Kutsche LK, Schuy ET, Sittl R, Hoffmann T, Alzheimer C, Huth T, Carr RW, Lampert A.

Mol Pain. 2012 Sep 15;8:69. doi: 10.1186/1744-8069-8-69.

30.

Double spikes to single electrical stimulation correlates to spontaneous activity of nociceptors in painful neuropathy patients.

Schmidt R, Kleggetveit IP, Namer B, Helås T, Obreja O, Schmelz M, Jørum E.

Pain. 2012 Feb;153(2):391-8. doi: 10.1016/j.pain.2011.10.041. Epub 2011 Dec 7.

PMID:
22154219
31.

Differential effects on sensory functions and measures of epidermal nerve fiber density after application of a lidocaine patch (5%) on healthy human skin.

Wehrfritz A, Namer B, Ihmsen H, Mueller C, Filitz J, Koppert W, Leffler A.

Eur J Pain. 2011 Oct;15(9):907-12. doi: 10.1016/j.ejpain.2011.03.011. Epub 2011 May 6.

PMID:
21530339
32.

Electrically induced quantitative sudomotor axon reflex test in human volunteers.

Sommer P, Kluschina O, Schley M, Namer B, Schmelz M, Rukwied R.

Auton Neurosci. 2011 Jan 20;159(1-2):111-6. doi: 10.1016/j.autneu.2010.09.004.

PMID:
20923721
33.

C-fiber axon reflex flare size correlates with epidermal nerve fiber density in human skin biopsies.

Bickel A, Heyer G, Senger C, Maihöfner C, Heuss D, Hilz MJ, Namer B.

J Peripher Nerv Syst. 2009 Dec;14(4):294-9. doi: 10.1111/j.1529-8027.2009.00241.x. Erratum in: J Peripher Nerv Syst. 2010 Jun;15(2):158. Maihoefner, Christian [corrected to Maihöfner, Christian].

PMID:
20021571
34.

Patterns of activity-dependent conduction velocity changes differentiate classes of unmyelinated mechano-insensitive afferents including cold nociceptors, in pig and in human.

Obreja O, Ringkamp M, Namer B, Forsch E, Klusch A, Rukwied R, Petersen M, Schmelz M.

Pain. 2010 Jan;148(1):59-69. doi: 10.1016/j.pain.2009.10.006. Epub 2009 Nov 13.

PMID:
19913997
35.

Age related changes in human C-fiber function.

Namer B.

Neurosci Lett. 2010 Feb 19;470(3):185-7. doi: 10.1016/j.neulet.2009.07.023. Epub 2009 Jul 14. Review. No abstract available.

PMID:
19607877
36.

Impact of scratching on itch and sympathetic reflexes induced by cowhage (Mucuna pruriens) and histamine.

Kosteletzky F, Namer B, Forster C, Handwerker HO.

Acta Derm Venereol. 2009;89(3):271-7. doi: 10.2340/00015555-0624.

37.

Translational nociceptor research as guide to human pain perceptions and pathophysiology.

Namer B, Handwerker HO.

Exp Brain Res. 2009 Jun;196(1):163-72. doi: 10.1007/s00221-009-1777-6. Epub 2009 Apr 7. Review.

PMID:
19350229
38.

Microneurographic assessment of C-fibre function in aged healthy subjects.

Namer B, Barta B, Ørstavik K, Schmidt R, Carr R, Schmelz M, Handwerker HO.

J Physiol. 2009 Jan 15;587(2):419-28. doi: 10.1113/jphysiol.2008.162941. Epub 2008 Dec 8.

39.

Separate peripheral pathways for pruritus in man.

Namer B, Carr R, Johanek LM, Schmelz M, Handwerker HO, Ringkamp M.

J Neurophysiol. 2008 Oct;100(4):2062-9. doi: 10.1152/jn.90482.2008. Epub 2008 Jun 18.

40.

Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury.

Namer B, Kleggetveit IP, Handwerker H, Schmelz M, Jorum E.

Pain. 2008 Sep 30;139(1):63-72. doi: 10.1016/j.pain.2008.03.007. Epub 2008 Apr 25.

PMID:
18440147
41.

Endothelin 1 activates and sensitizes human C-nociceptors.

Namer B, Hilliges M, Orstavik K, Schmidt R, Weidner C, Torebjörk E, Handwerker H, Schmelz M.

Pain. 2008 Jul;137(1):41-9. Epub 2007 Sep 19.

PMID:
17884295
42.

Abnormal function of C-fibers in patients with diabetic neuropathy.

Ørstavik K, Namer B, Schmidt R, Schmelz M, Hilliges M, Weidner C, Carr RW, Handwerker H, Jørum E, Torebjörk HE.

J Neurosci. 2006 Nov 1;26(44):11287-94.

43.

Catecholamine-induced excitation of nociceptors in sympathetically maintained pain.

Jørum E, Ørstavik K, Schmidt R, Namer B, Carr RW, Kvarstein G, Hilliges M, Handwerker H, Torebjörk E, Schmelz M.

Pain. 2007 Feb;127(3):296-301. Epub 2006 Sep 25.

PMID:
16997471
44.

Subtotal nephrectomy impairs ischemia-induced angiogenesis and hindlimb re-perfusion in rats.

Jacobi J, Porst M, Cordasic N, Namer B, Schmieder RE, Eckardt KU, Hilgers KF.

Kidney Int. 2006 Jun;69(11):2013-21.

45.

TRPA1 and TRPM8 activation in humans: effects of cinnamaldehyde and menthol.

Namer B, Seifert F, Handwerker HO, Maihöfner C.

Neuroreport. 2005 Jun 21;16(9):955-9.

PMID:
15931068
46.

Chemically and electrically induced sweating and flare reaction.

Namer B, Bickel A, Krämer H, Birklein F, Schmelz M.

Auton Neurosci. 2004 Jul 30;114(1-2):72-82.

PMID:
15331047

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