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Items: 48

1.

Regulatory Forum Commentary* Counterpoint: Dose Selection for rasH2 Mouse Carcinogenicity Studies.

Nambiar PR, Morton D.

Toxicol Pathol. 2015 Jul;43(5):628-32. doi: 10.1177/0192623315578012. Epub 2015 Apr 22.

PMID:
25903268
2.

Two-year carcinogenicity study in rats with a nonnucleoside reverse transcriptase inhibitor.

Nambiar PR, Morton D, Dochterman LW, Houle C, Thomford PJ, Fate G, Bailey SA, Finch GL.

Toxicol Pathol. 2015 Apr;43(3):354-65. doi: 10.1177/0192623314544381. Epub 2014 Aug 13.

PMID:
25122632
3.

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas.

Danilenko DM, Nambiar PR, Cesta MF.

Vet Pathol. 2014 Mar;51(2):541-4. doi: 10.1177/0300985813519133. Epub 2014 Jan 17. No abstract available.

PMID:
24442576
4.

Toxicities associated with 1-month treatment with propylthiouracil (PTU) and methimazole (MMI) in male rats.

Nambiar PR, Palanisamy GS, Okerberg C, Wolford A, Walters K, Buckbinder L, Reagan WJ.

Toxicol Pathol. 2014 Aug;42(6):970-83. doi: 10.1177/0192623313502708. Epub 2013 Sep 25.

PMID:
24067673
5.

A brief overview of the 32nd Annual STP Symposium on the Toxicologic Pathology of the Digestive Tract and Pancreas.

Danilenko DM, Nambiar PR, Cesta MF.

Toxicol Pathol. 2014 Jan;42(1):45-8. doi: 10.1177/0192623313502402. Epub 2013 Sep 2. No abstract available.

PMID:
24002990
6.

Regulatory Forum commentary: alternative mouse models for future cancer risk assessment.

Morton D, Sistare FD, Nambiar PR, Turner OC, Radi Z, Bower N.

Toxicol Pathol. 2014 Jul;42(5):799-806. doi: 10.1177/0192623313502130. Epub 2013 Aug 21.

PMID:
23965809
7.

The rasH2 mouse model for assessing carcinogenic potential of pharmaceuticals.

Nambiar PR, Morton D.

Toxicol Pathol. 2013;41(8):1058-67. doi: 10.1177/0192623313477257. Epub 2013 Feb 19. Erratum in: Toxicol Pathol. 2016 Jun;44(4):624.

PMID:
23423820
8.

Expression of TMPRSS4 in non-small cell lung cancer and its modulation by hypoxia.

Nguyen TH, Weber W, Havari E, Connors T, Bagley RG, McLaren R, Nambiar PR, Madden SL, Teicher BA, Roberts B, Kaplan J, Shankara S.

Int J Oncol. 2012 Sep;41(3):829-38. doi: 10.3892/ijo.2012.1513. Epub 2012 Jun 12.

9.

Spontaneous tumor incidence in rasH2 mice: review of internal data and published literature.

Nambiar PR, Turnquist SE, Morton D.

Toxicol Pathol. 2012 Jun;40(4):614-23. doi: 10.1177/0192623311436181. Epub 2012 Feb 9.

PMID:
22328410
10.

An "Omics" based survey of human colon cancer.

Nambiar PR, Gupta RR, Misra V.

Mutat Res. 2010 Nov 10;693(1-2):3-18. doi: 10.1016/j.mrfmmm.2010.07.008. Epub 2010 Aug 5. Review.

PMID:
20691711
11.

Staphylococcal meningoencephalitis, nematodiasis, and typhlocolitis in a squirrel monkey (Saimiri sciureus).

García A, Nambiar PR, Marini RP, Fox JG.

J Med Primatol. 2009 Oct;38(5):377-81. doi: 10.1111/j.1600-0684.2009.00363.x.

PMID:
19737242
12.

Diarrhea as a cause of mortality in a mouse model of infectious colitis.

Borenshtein D, Fry RC, Groff EB, Nambiar PR, Carey VJ, Fox JG, Schauer DB.

Genome Biol. 2008;9(8):R122. doi: 10.1186/gb-2008-9-8-r122. Epub 2008 Aug 4.

13.

Obesity and non-insulin-dependent diabetes mellitus in Swiss-Webster mice associated with late-onset hepatocellular carcinoma.

Lemke LB, Rogers AB, Nambiar PR, Fox JG.

J Endocrinol. 2008 Oct;199(1):21-32. doi: 10.1677/JOE-07-0588. Epub 2008 Jul 30.

PMID:
18667586
14.

Infestation of wild-caught American bullfrogs (Rana catesbeiana) by multiple species of metazoan parasites.

Lemke LB, Dronen N, Fox JG, Nambiar PR.

J Am Assoc Lab Anim Sci. 2008 May;47(3):42-6.

15.

Genetic deletion of mPGES-1 suppresses intestinal tumorigenesis.

Nakanishi M, Montrose DC, Clark P, Nambiar PR, Belinsky GS, Claffey KP, Xu D, Rosenberg DW.

Cancer Res. 2008 May 1;68(9):3251-9. doi: 10.1158/0008-5472.CAN-07-6100.

16.

Agammaglobulinemia and Staphylococcus aureus botryomycosis in a cohort of related sentinel Swiss Webster mice.

Bridgeford EC, Fox JG, Nambiar PR, Rogers AB.

J Clin Microbiol. 2008 May;46(5):1881-4. doi: 10.1128/JCM.01875-07. Epub 2008 Mar 5.

17.

Rapid reversal of interleukin-6-dependent epithelial invasion in a mouse model of microbially induced colon carcinoma.

Poutahidis T, Haigis KM, Rao VP, Nambiar PR, Taylor CL, Ge Z, Watanabe K, Davidson A, Horwitz BH, Fox JG, Erdman SE.

Carcinogenesis. 2007 Dec;28(12):2614-23. Epub 2007 Aug 27.

PMID:
17724375
18.

Development of fatal colitis in FVB mice infected with Citrobacter rodentium.

Borenshtein D, Nambiar PR, Groff EB, Fox JG, Schauer DB.

Infect Immun. 2007 Jul;75(7):3271-81. Epub 2007 Apr 30.

19.

Trefoil family factor 2 is expressed in murine gastric and immune cells and controls both gastrointestinal inflammation and systemic immune responses.

Kurt-Jones EA, Cao L, Sandor F, Rogers AB, Whary MT, Nambiar PR, Cerny A, Bowen G, Yan J, Takaishi S, Chi AL, Reed G, Houghton J, Fox JG, Wang TC.

Infect Immun. 2007 Jan;75(1):471-80. Epub 2006 Nov 13.

20.

Inhibition of Helicobacter hepaticus-induced colitis by IL-10 requires the p50/p105 subunit of NF-kappa B.

Tomczak MF, Erdman SE, Davidson A, Wang YY, Nambiar PR, Rogers AB, Rickman B, Luchetti D, Fox JG, Horwitz BH.

J Immunol. 2006 Nov 15;177(10):7332-9.

21.

Enterohepatic Helicobacter species isolated from the ileum, liver and colon of a baboon with pancreatic islet amyloidosis.

García A, Xu S, Dewhirst FE, Nambiar PR, Fox JG.

J Med Microbiol. 2006 Nov;55(Pt 11):1591-5.

PMID:
17030922
22.

Circumvention and reactivation of the p53 oncogene checkpoint in mouse colon tumors.

Aizu W, Belinsky GS, Flynn C, Noonan EJ, Boes CC, Godman CA, Doshi B, Nambiar PR, Rosenberg DW, Giardina C.

Biochem Pharmacol. 2006 Oct 16;72(8):981-91. Epub 2006 Sep 1.

PMID:
16949053
23.

Innate immune inflammatory response against enteric bacteria Helicobacter hepaticus induces mammary adenocarcinoma in mice.

Rao VP, Poutahidis T, Ge Z, Nambiar PR, Boussahmain C, Wang YY, Horwitz BH, Fox JG, Erdman SE.

Cancer Res. 2006 Aug 1;66(15):7395-400.

24.

Effect of tissue preservation on imaging using ultrahigh resolution optical coherence tomography.

Hsiung PL, Nambiar PR, Fujimoto JG.

J Biomed Opt. 2005 Nov-Dec;10(6):064033.

25.

Progressive proliferative and dysplastic typhlocolitis in aging syrian hamsters naturally infected with Helicobacter spp.: a spontaneous model of inflammatory bowel disease.

Nambiar PR, Kirchain SM, Courmier K, Xu S, Taylor NS, Theve EJ, Patterson MM, Fox JG.

Vet Pathol. 2006 Jan;43(1):2-14.

PMID:
16407482
26.

Immunomodulatory effects of in vitro exposure to organochlorines on T-cell proliferation in marine mammals and mice.

Mori C, Morsey B, Levin M, Nambiar PR, De Guise S.

J Toxicol Environ Health A. 2006 Feb;69(3-4):283-302.

PMID:
16407088
27.

Proinflammatory CD4+ CD45RB(hi) lymphocytes promote mammary and intestinal carcinogenesis in Apc(Min/+) mice.

Rao VP, Poutahidis T, Ge Z, Nambiar PR, Horwitz BH, Fox JG, Erdman SE.

Cancer Res. 2006 Jan 1;66(1):57-61.

28.

Acute paraplegia in a young adult long-evans rat resulting from T-cell lymphoma.

Nagamine CM, Jackson CN, Beck KA, Marini RP, Fox JG, Nambiar PR.

Contemp Top Lab Anim Sci. 2005 Nov;44(6):53-6.

PMID:
16370582
29.

Global gene expression profiling: a complement to conventional histopathologic analysis of neoplasia.

Nambiar PR, Boutin SR, Raja R, Rosenberg DW.

Vet Pathol. 2005 Nov;42(6):735-52. Review.

PMID:
16301570
30.

Non-coplanar PCB-mediated modulation of human leukocyte phagocytosis: a new mechanism for immunotoxicity.

Levin M, Morsey B, Mori C, Nambiar PR, De Guise S.

J Toxicol Environ Health A. 2005 Nov 26;68(22):1977-93.

PMID:
16263690
31.
32.

Cytolethal distending toxin is essential for Helicobacter hepaticus colonization in outbred Swiss Webster mice.

Ge Z, Feng Y, Whary MT, Nambiar PR, Xu S, Ng V, Taylor NS, Fox JG.

Infect Immun. 2005 Jun;73(6):3559-67.

33.

PCBs and TCDD, alone and in mixtures, modulate marine mammal but not B6C3F1 mouse leukocyte phagocytosis.

Levin M, Morsey B, Mori C, Nambiar PR, De Guise S.

J Toxicol Environ Health A. 2005 Apr 23;68(8):635-56.

PMID:
15901092
34.

CD4+CD25+ regulatory lymphocytes induce regression of intestinal tumors in ApcMin/+ mice.

Erdman SE, Sohn JJ, Rao VP, Nambiar PR, Ge Z, Fox JG, Schauer DB.

Cancer Res. 2005 May 15;65(10):3998-4004.

35.
36.
37.

Hepatic temporal gene expression profiling in Helicobacter hepaticus-infected A/JCr mice.

Boutin SR, Rogers AB, Shen Z, Fry RC, Love JA, Nambiar PR, Suerbaum S, Fox JG.

Toxicol Pathol. 2004 Nov-Dec;32(6):678-93.

PMID:
15513911
38.

Genetic signatures of high- and low-risk aberrant crypt foci in a mouse model of sporadic colon cancer.

Nambiar PR, Nakanishi M, Gupta R, Cheung E, Firouzi A, Ma XJ, Flynn C, Dong M, Guda K, Levine J, Raja R, Achenie L, Rosenberg DW.

Cancer Res. 2004 Sep 15;64(18):6394-401.

39.

Azoxymethane-induced pre-adipocyte factor 1 (Pref-1) functions as a differentiation inhibitor in colonic epithelial cells.

Dong M, Guda K, Nambiar PR, Nakanishi M, Lichtler AC, Nishikawa M, Giardina C, Rosenberg DW.

Carcinogenesis. 2004 Nov;25(11):2239-46. Epub 2004 Aug 5.

PMID:
15297369
40.

Microgenomics: Identification of new expression profiles via small and single-cell sample analyses.

Taylor TB, Nambiar PR, Raja R, Cheung E, Rosenberg DW, Anderegg B.

Cytometry A. 2004 Jun;59(2):254-61. Review.

41.

Defective processing of the transforming growth factor-beta1 in azoxymethane-induced mouse colon tumors.

Guda K, Claffey KP, Dong M, Nambiar PR, Rosenberg DW.

Mol Carcinog. 2003 May;37(1):51-9.

PMID:
12720300
42.

Multistage gene expression profiling in a differentially susceptible mouse colon cancer model.

Guda K, Cui H, Garg S, Dong M, Nambiar PR, Achenie LE, Rosenberg DW.

Cancer Lett. 2003 Feb 28;191(1):17-25.

PMID:
12609705
43.

Inverse association between phospholipase A2 and COX-2 expression during mouse colon tumorigenesis.

Dong M, Guda K, Nambiar PR, Rezaie A, Belinsky GS, Lambeau G, Giardina C, Rosenberg DW.

Carcinogenesis. 2003 Feb;24(2):307-15.

PMID:
12584182
44.

Preliminary analysis of azoxymethane induced colon tumors in inbred mice commonly used as transgenic/knockout progenitors.

Nambiar PR, Girnun G, Lillo NA, Guda K, Whiteley HE, Rosenberg DW.

Int J Oncol. 2003 Jan;22(1):145-50.

PMID:
12469197
45.

Role of the alternating reading frame (P19)-p53 pathway in an in vivo murine colon tumor model.

Nambiar PR, Giardina C, Guda K, Aizu W, Raja R, Rosenberg DW.

Cancer Res. 2002 Jul 1;62(13):3667-74.

46.

Immunohistochemical detection of tumor suppressor gene p53 protein in feline injection site-associated sarcomas.

Nambiar PR, Jackson ML, Ellis JA, Chelack BJ, Kidney BA, Haines DM.

Vet Pathol. 2001 Mar;38(2):236-8.

PMID:
11280384
47.

Mutational analysis of tumor suppressor gene p53 in feline vaccine site-associated sarcomas.

Nambiar PR, Haines DM, Ellis JA, Kidney BA, Jackson ML.

Am J Vet Res. 2000 Oct;61(10):1277-81.

PMID:
11039561
48.

Differential expression of p16(INK4a) in azoxymethane-induced mouse colon tumorigenesis.

Wang QS, Papanikolaou A, Nambiar PR, Rosenberg DW.

Mol Carcinog. 2000 Jul;28(3):139-47.

PMID:
10942530

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