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Items: 10

1.

Graft-versus-host disease propagation depends on increased intestinal epithelial tight junction permeability.

Nalle SC, Zuo L, Ong MLDM, Singh G, Worthylake AM, Choi W, Manresa MC, Southworth AP, Edelblum KL, Baker GJ, Joseph NE, Savage PA, Turner JR.

J Clin Invest. 2019 Feb 1;129(2):902-914. doi: 10.1172/JCI98554. Epub 2019 Jan 22.

2.

FRET Reagent Reveals the Intracellular Processing of Peptide-Linked Antibody-Drug Conjugates.

Lee BC, Chalouni C, Doll S, Nalle SC, Darwish M, Tsai SP, Kozak KR, Del-Rosario G, Yu SF, Erickson H, Vandlen R.

Bioconjug Chem. 2018 Jul 18;29(7):2468-2477. doi: 10.1021/acs.bioconjchem.8b00362. Epub 2018 Jun 13.

PMID:
29856915
3.

Intestinal barrier loss as a critical pathogenic link between inflammatory bowel disease and graft-versus-host disease.

Nalle SC, Turner JR.

Mucosal Immunol. 2015 Jul;8(4):720-30. doi: 10.1038/mi.2015.40. Epub 2015 May 6. Review.

PMID:
25943273
4.

Recipient NK cell inactivation and intestinal barrier loss are required for MHC-matched graft-versus-host disease.

Nalle SC, Kwak HA, Edelblum KL, Joseph NE, Singh G, Khramtsova GF, Mortenson ED, Savage PA, Turner JR.

Sci Transl Med. 2014 Jul 2;6(243):243ra87. doi: 10.1126/scitranslmed.3008941.

5.

TNFR2 activates MLCK-dependent tight junction dysregulation to cause apoptosis-mediated barrier loss and experimental colitis.

Su L, Nalle SC, Shen L, Turner ES, Singh G, Breskin LA, Khramtsova EA, Khramtsova G, Tsai PY, Fu YX, Abraham C, Turner JR.

Gastroenterology. 2013 Aug;145(2):407-15. doi: 10.1053/j.gastro.2013.04.011. Epub 2013 Apr 22.

6.

Endothelial and epithelial barriers in graft-versus-host disease.

Nalle SC, Turner JR.

Adv Exp Med Biol. 2012;763:105-31.

PMID:
23397621
7.

Menetrier's disease therapy: rebooting mucosal signaling.

Nalle SC, Turner JR.

Sci Transl Med. 2009 Nov 25;1(8):8ps10. doi: 10.1126/scitranslmed.3000438.

PMID:
20368184
8.

Epithelium, tear down this wall!

Nalle SC, Turner JR.

Cell Host Microbe. 2009 Jan 22;5(1):1-2. doi: 10.1016/j.chom.2008.12.008.

9.

Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis.

Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR.

Gastroenterology. 2009 Feb;136(2):551-63. doi: 10.1053/j.gastro.2008.10.081. Epub 2008 Nov 6.

10.

Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation.

Weber CR, Nalle SC, Tretiakova M, Rubin DT, Turner JR.

Lab Invest. 2008 Oct;88(10):1110-20. doi: 10.1038/labinvest.2008.78. Epub 2008 Aug 18.

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