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Items: 19

1.

Prospects for Foamy Viral Vector Anti-HIV Gene Therapy.

Nalla AK, Trobridge GD.

Biomedicines. 2016 Mar 29;4(2). pii: E8. doi: 10.3390/biomedicines4020008. Review.

2.

Lentiviral vector-mediated insertional mutagenesis screen identifies genes that influence androgen independent prostate cancer progression and predict clinical outcome.

Nalla AK, Williams TF, Collins CP, Rae DT, Trobridge GD.

Mol Carcinog. 2016 Nov;55(11):1761-1771. doi: 10.1002/mc.22425. Epub 2015 Oct 29.

3.

Irradiation-induced angiogenesis is associated with an MMP-9-miR-494-syndecan-1 regulatory loop in medulloblastoma cells.

Asuthkar S, Velpula KK, Nalla AK, Gogineni VR, Gondi CS, Rao JS.

Oncogene. 2014 Apr 10;33(15):1922-33. doi: 10.1038/onc.2013.151. Epub 2013 Jun 3.

PMID:
23728345
4.

Radiation-induced hypomethylation triggers urokinase plasminogen activator transcription in meningioma cells.

Velpula KK, Gogineni VR, Nalla AK, Dinh DH, Rao JS.

Neoplasia. 2013 Feb;15(2):192-203.

5.

uPAR and cathepsin B shRNA impedes TGF-β1-driven proliferation and invasion of meningioma cells in a XIAP-dependent pathway.

Gogineni VR, Gupta R, Nalla AK, Velpula KK, Rao JS.

Cell Death Dis. 2012 Dec 6;3:e439. doi: 10.1038/cddis.2012.170.

6.

Apoptosis induced by knockdown of uPAR and MMP-9 is mediated by inactivation of EGFR/STAT3 signaling in medulloblastoma.

Kotipatruni RR, Nalla AK, Asuthkar S, Gondi CS, Dinh DH, Rao JS.

PLoS One. 2012;7(9):e44798. doi: 10.1371/journal.pone.0044798. Epub 2012 Sep 12.

7.

Urokinase-type plasminogen activator receptor (uPAR)-mediated regulation of WNT/β-catenin signaling is enhanced in irradiated medulloblastoma cells.

Asuthkar S, Gondi CS, Nalla AK, Velpula KK, Gorantla B, Rao JS.

J Biol Chem. 2012 Jun 8;287(24):20576-89. doi: 10.1074/jbc.M112.348888. Epub 2012 Apr 16.

8.

uPA and uPAR shRNA inhibit angiogenesis via enhanced secretion of SVEGFR1 independent of GM-CSF but dependent on TIMP-1 in endothelial and glioblastoma cells.

Raghu H, Nalla AK, Gondi CS, Gujrati M, Dinh DH, Rao JS.

Mol Oncol. 2012 Feb;6(1):33-47. doi: 10.1016/j.molonc.2011.11.008. Epub 2011 Nov 30.

9.

Chk2-mediated G2/M cell cycle arrest maintains radiation resistance in malignant meningioma cells.

Gogineni VR, Nalla AK, Gupta R, Dinh DH, Klopfenstein JD, Rao JS.

Cancer Lett. 2011 Dec 26;313(1):64-75. doi: 10.1016/j.canlet.2011.08.022. Epub 2011 Sep 6. Erratum in: Cancer Lett. 2014 Jul 28;349(2):155.

10.

N-cadherin mediates angiogenesis by regulating monocyte chemoattractant protein-1 expression via PI3K/Akt signaling in prostate cancer cells.

Nalla AK, Estes N, Patel J, Rao JS.

Exp Cell Res. 2011 Oct 15;317(17):2512-21. doi: 10.1016/j.yexcr.2011.07.024. Epub 2011 Aug 9.

PMID:
21855541
11.

Gadd45a sensitizes medulloblastoma cells to irradiation and suppresses MMP-9-mediated EMT.

Asuthkar S, Nalla AK, Gondi CS, Dinh DH, Gujrati M, Mohanam S, Rao JS.

Neuro Oncol. 2011 Oct;13(10):1059-73. doi: 10.1093/neuonc/nor109. Epub 2011 Aug 2.

12.

α3β1 integrin promotes radiation-induced migration of meningioma cells.

Gogineni VR, Nalla AK, Gupta R, Gujrati M, Klopfenstein JD, Mohanam S, Rao JS.

Int J Oncol. 2011 Jun;38(6):1615-24. doi: 10.3892/ijo.2011.987. Epub 2011 Mar 29.

13.

Suppression of uPA and uPAR blocks radiation-induced MCP-1 mediated recruitment of endothelial cells in meningioma.

Nalla AK, Gogineni VR, Gupta R, Dinh DH, Rao JS.

Cell Signal. 2011 Aug;23(8):1299-310. doi: 10.1016/j.cellsig.2011.03.011. Epub 2011 Mar 21. Erratum in: Cell Signal. 2013 Aug;25(8):1730.

14.

uPAR/cathepsin B overexpression reverse angiogenesis by rescuing FAK phosphorylation in uPAR/cathepsin B down regulated meningioma.

Gupta R, Nalla AK, Gogineni VR, Chetty C, Bhoopathi P, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS.

PLoS One. 2011 Feb 11;6(2):e17123. doi: 10.1371/journal.pone.0017123.

15.

Oncogenic role of p53 is suppressed by si-RNA bicistronic construct of uPA, uPAR and cathepsin-B in meningiomas both in vitro and in vivo.

Gupta R, Rao Gogineni V, Nalla AK, Chetty C, Klopfenstein JD, Tsung AJ, Mohanam S, Rao JS.

Int J Oncol. 2011 Apr;38(4):973-83. doi: 10.3892/ijo.2011.934. Epub 2011 Feb 2.

16.

siRNA-mediated downregulation of MMP-9 and uPAR in combination with radiation induces G2/M cell-cycle arrest in Medulloblastoma.

Nagaraju GP, Nalla AK, Gupta R, Mohanam S, Gujrati M, Dinh DH, Rao JS.

Mol Cancer Res. 2011 Jan;9(1):51-66. doi: 10.1158/1541-7786.MCR-10-0399. Epub 2010 Dec 10.

17.

Suppression of uPAR retards radiation-induced invasion and migration mediated by integrin β1/FAK signaling in medulloblastoma.

Nalla AK, Asuthkar S, Bhoopathi P, Gujrati M, Dinh DH, Rao JS.

PLoS One. 2010 Sep 24;5(9):e13006. doi: 10.1371/journal.pone.0013006.

18.

Oxidative stimuli-responsive nanoprodrug of camptothecin kills glioblastoma cells.

Lee BS, Nalla AK, Stock IR, Shear TC, Black KL, Yu JS.

Bioorg Med Chem Lett. 2010 Sep 1;20(17):5262-8. doi: 10.1016/j.bmcl.2010.06.144. Epub 2010 Jul 23. Erratum in: Bioorg Med Chem Lett. 2011 Dec 1;21(23):7229.

PMID:
20655220
19.

Targeting MMP-9, uPAR, and cathepsin B inhibits invasion, migration and activates apoptosis in prostate cancer cells.

Nalla AK, Gorantla B, Gondi CS, Lakka SS, Rao JS.

Cancer Gene Ther. 2010 Sep;17(9):599-613. doi: 10.1038/cgt.2010.16. Epub 2010 May 7.

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