Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 71

1.

Taurine improves glucose tolerance in STZ-induced insulin-deficient diabetic mice.

Nakatsuru Y, Murase-Mishiba Y, Bessho-Tachibana M, Terasaki J, Hanafusa T, Imagawa A.

Diabetol Int. 2018 Mar 19;9(4):234-242. doi: 10.1007/s13340-018-0353-3. eCollection 2018 Oct.

2.

Evaluating Chemical CDK Inhibitors as Cell Death Inducers.

Hirai H, Nakatsuru Y.

Methods Mol Biol. 2016;1336:167-78. doi: 10.1007/978-1-4939-2926-9_14.

PMID:
26231716
3.

MK-2206, an allosteric Akt inhibitor, enhances antitumor efficacy by standard chemotherapeutic agents or molecular targeted drugs in vitro and in vivo.

Hirai H, Sootome H, Nakatsuru Y, Miyama K, Taguchi S, Tsujioka K, Ueno Y, Hatch H, Majumder PK, Pan BS, Kotani H.

Mol Cancer Ther. 2010 Jul;9(7):1956-67. doi: 10.1158/1535-7163.MCT-09-1012. Epub 2010 Jun 22.

4.

Biological characterization of 2-aminothiazole-derived Cdk4/6 selective inhibitor in vitro and in vivo.

Hirai H, Shimomura T, Kobayashi M, Eguchi T, Taniguchi E, Fukasawa K, Machida T, Oki H, Arai T, Ichikawa K, Hasako S, Haze K, Kodera T, Kawanishi N, Takahashi-Suziki I, Nakatsuru Y, Kotani H, Iwasawa Y.

Cell Cycle. 2010 Apr 15;9(8):1590-600. Epub 2010 Apr 15.

PMID:
20372067
5.

Potent anti-tumor activity of a macrocycle-quinoxalinone class pan-Cdk inhibitor in vitro and in vivo.

Hirai H, Takahashi-Suziki I, Shimomura T, Fukasawa K, Machida T, Takaki T, Kobayashi M, Eguchi T, Oki H, Arai T, Ichikawa K, Hasako S, Kodera T, Kawanishi N, Nakatsuru Y, Kotani H, Iwasawa Y.

Invest New Drugs. 2011 Aug;29(4):534-43. doi: 10.1007/s10637-009-9384-8. Epub 2010 Jan 19.

PMID:
20084424
6.

MK-5108, a highly selective Aurora-A kinase inhibitor, shows antitumor activity alone and in combination with docetaxel.

Shimomura T, Hasako S, Nakatsuru Y, Mita T, Ichikawa K, Kodera T, Sakai T, Nambu T, Miyamoto M, Takahashi I, Miki S, Kawanishi N, Ohkubo M, Kotani H, Iwasawa Y.

Mol Cancer Ther. 2010 Jan;9(1):157-66. doi: 10.1158/1535-7163.MCT-09-0609. Epub 2010 Jan 6.

7.

Imidazopyridine derivatives as potent and selective Polo-like kinase (PLK) inhibitors.

Sato Y, Onozaki Y, Sugimoto T, Kurihara H, Kamijo K, Kadowaki C, Tsujino T, Watanabe A, Otsuki S, Mitsuya M, Iida M, Haze K, Machida T, Nakatsuru Y, Komatani H, Kotani H, Iwasawa Y.

Bioorg Med Chem Lett. 2009 Aug 15;19(16):4673-8. doi: 10.1016/j.bmcl.2009.06.084. Epub 2009 Jun 25.

PMID:
19589677
8.

A case of cortisol producing adrenal adenoma without phenotype of Cushing's syndrome due to impaired 11beta-hydroxysteroid dehydrogenase 1 activity.

Arai H, Kobayashi N, Nakatsuru Y, Masuzaki H, Nambu T, Takaya K, Yamanaka Y, Kondo E, Yamada G, Fujii T, Miura M, Komatsu Y, Kanamoto N, Ariyasu H, Moriyama K, Yasoda A, Nakao K.

Endocr J. 2008 Aug;55(4):709-15. Epub 2008 May 21.

9.

Aryl hydrocarbon receptor plays a significant role in mediating airborne particulate-induced carcinogenesis in mice.

Matsumoto Y, Ide F, Kishi R, Akutagawa T, Sakai S, Nakamura M, Ishikawa T, Fujii-Kuriyama Y, Nakatsuru Y.

Environ Sci Technol. 2007 May 15;41(10):3775-80.

PMID:
17547212
10.

Complementary antagonistic actions between C-type natriuretic peptide and the MAPK pathway through FGFR-3 in ATDC5 cells.

Ozasa A, Komatsu Y, Yasoda A, Miura M, Sakuma Y, Nakatsuru Y, Arai H, Itoh N, Nakao K.

Bone. 2005 Jun;36(6):1056-64.

PMID:
15869918
11.

[Not Available].

Komatsu Y, Nakajima R, Yasoda A, Nakatsuru Y, Arai H, Nakao K, Shigeno C.

Clin Calcium. 2003 Sep;13(9):1188-92. Japanese. No abstract available.

PMID:
15775201
12.

Dibenzo[A,L]pyrene-induced genotoxic and carcinogenic responses are dramatically suppressed in aryl hydrocarbon receptor-deficient mice.

Nakatsuru Y, Wakabayashi K, Fujii-Kuriyama Y, Ishikawa T, Kusama K, Ide F.

Int J Cancer. 2004 Nov 1;112(2):179-83.

13.

Usefulness of FDG-PET in detecting an ADH-secreting tumor: a case report.

Ihara C, Nakamoto Y, Nakatsuru Y, Yano J, Sakamoto S, Nanno M, Koshiyama H.

Eur J Intern Med. 2004 Jun;15(3):181-182.

PMID:
15245722
14.

DNA repair and cancer: lessons from mutant mouse models.

Ishikawa T, Zhang SS, Qin X, Takahashi Y, Oda H, Nakatsuru Y, Ide F.

Cancer Sci. 2004 Feb;95(2):112-7. Review.

15.

Metallothionein deficiency enhances skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate in metallothionein-null mice.

Suzuki JS, Nishimura N, Zhang B, Nakatsuru Y, Kobayashi S, Satoh M, Tohyama C.

Carcinogenesis. 2003 Jun;24(6):1123-32. Epub 2003 Mar 28.

PMID:
12807749
16.

Base excision repair as a therapeutic target in colon cancer.

Liu L, Nakatsuru Y, Gerson SL.

Clin Cancer Res. 2002 Sep;8(9):2985-91.

17.

Enhanced spontaneous and aflatoxin-induced liver tumorigenesis in xeroderma pigmentosum group A gene-deficient mice.

Takahashi Y, Nakatsuru Y, Zhang S, Shimizu Y, Kume H, Tanaka K, Ide F, Ishikawa T.

Carcinogenesis. 2002 Apr;23(4):627-33.

PMID:
11960916
18.

Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase.

Tsuzuki T, Egashira A, Igarashi H, Iwakuma T, Nakatsuru Y, Tominaga Y, Kawate H, Nakao K, Nakamura K, Ide F, Kura S, Nakabeppu Y, Katsuki M, Ishikawa T, Sekiguchi M.

Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11456-61.

19.

Morphological and physiological restorations of hereditary form of dilated cardiomyopathy by somatic gene therapy.

Kawada T, Sakamoto A, Nakazawa M, Urabe M, Masuda F, Hemmi C, Wang Y, Shin WS, Nakatsuru Y, Sato H, Ozawa K, Toyo-oka T.

Biochem Biophys Res Commun. 2001 Jun 8;284(2):431-5.

PMID:
11394897
20.

Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies.

Ishikawa T, Ide F, Qin X, Zhang S, Takahashi Y, Sekiguchi M, Tanaka K, Nakatsuru Y.

Mutat Res. 2001 Jun 2;477(1-2):41-9. Review.

PMID:
11376685
21.

Xeroderma pigmentosum group A gene action as a protection factor against 4-nitroquinoline 1-oxide-induced tongue carcinogenesis.

Ide F, Oda H, Nakatsuru Y, Kusama K, Sakashita H, Tanaka K, Ishikawa T.

Carcinogenesis. 2001 Apr;22(4):567-72.

PMID:
11285190
22.

Protection against malignant progression of spontaneously developing liver tumors in transgenic mice expressing O(6)-methylguanine-DNA methyltransferase.

Qin X, Zhang S, Matsukuma S, Zarkovic M, Shimizu S, Ishikawa T, Nakatsuru Y.

Jpn J Cancer Res. 2000 Nov;91(11):1085-9.

23.

Genetic identification of bilateral primary or metastatic nonpapillary renal cell carcinoma.

Kume H, Oda H, Nakatsuru Y, Shimizu Y, Takahashi Y, Matsumoto T, Inoue T, Kameyama S, Kitamura T, Ishikawa T.

BJU Int. 2000 Aug;86(3):208-12.

24.

Mice deficient in the nucleotide excision repair gene XPA have elevated sensitivity to benzo[a]pyrene induction of lung tumors.

Ide F, Iida N, Nakatsuru Y, Oda H, Tanaka K, Ishikawa T.

Carcinogenesis. 2000 Jun;21(6):1263-5.

PMID:
10837020
25.

In vivo detection of ultraviolet photoproducts and their repair in purkinje cells.

Ide F, Iida N, Nakatsuru Y, Oda H, Nikaido O, Ishikawa T.

Lab Invest. 2000 Apr;80(4):465-70.

PMID:
10780663
26.

Eel WT1 sequence and expression in spontaneous nephroblastomas in Japanese eel.

Nakatsuru Y, Minami K, Yoshikawa A, Zhu J, Oda H, Masahito P, Okamoto N, Nakamura Y, Ishikawa T.

Gene. 2000 Mar 21;245(2):245-51.

PMID:
10717475
27.

Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor.

Shimizu Y, Nakatsuru Y, Ichinose M, Takahashi Y, Kume H, Mimura J, Fujii-Kuriyama Y, Ishikawa T.

Proc Natl Acad Sci U S A. 2000 Jan 18;97(2):779-82.

28.

Inhibition of skin cancer by IP6 in vivo: initiation-promotion model.

Ishikawa T, Nakatsuru Y, Zarkovic M, Shamsuddin AM.

Anticancer Res. 1999 Sep-Oct;19(5A):3749-52.

PMID:
10625952
29.

Strain- and age-dependent loss of sarcoglycan complex in cardiomyopathic hamster hearts and its re-expression by delta-sarcoglycan gene transfer in vivo.

Kawada T, Nakatsuru Y, Sakamoto A, Koizumi T, Shin WS, Okai-Matsuo Y, Suzuki J, Uehara Y, Nakazawa M, Sato H, Ishikawa T, Toyo-oka T.

FEBS Lett. 1999 Sep 24;458(3):405-8.

30.

Precise identification of gene products in hearts after in vivo gene transfection, using Sendai virus-coated proteoliposomes.

Kawada T, Shin WS, Nakatsuru Y, Koizumi T, Sakamoto A, Nakajima T, Okai-Matsuo Y, Nakazawa M, Sato H, Ishikawa T, Toyo-Oka T.

Biochem Biophys Res Commun. 1999 Jun 7;259(2):408-13.

PMID:
10362522
31.

Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53.

Nozawa H, Oda E, Nakao K, Ishihara M, Ueda S, Yokochi T, Ogasawara K, Nakatsuru Y, Shimizu S, Ohira Y, Hioki K, Aizawa S, Ishikawa T, Katsuki M, Muto T, Taniguchi T, Tanaka N.

Genes Dev. 1999 May 15;13(10):1240-5.

32.

Possible rare involvement of O6-methylguanine formation as a significant mutational factor in mouse urinary bladder carcinogenesis models.

Chen T, Yamamoto S, Kitano M, Murai T, Wanibuchi H, Matsukuma S, Nakatsuru Y, Ishikawa T, Fukushima S.

Teratog Carcinog Mutagen. 1998;18(3):101-10.

PMID:
9728794
33.

cDNA cloning and developmental expression of the porcine homologue of WT1.

Tsurutani N, Oda H, Nakatsuru Y, Imai Y, Zhang S, Ueno Y, Ishikawa T.

Gene. 1998 May 12;211(2):215-20.

PMID:
9602131
34.

Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes.

Kawate H, Sakumi K, Tsuzuki T, Nakatsuru Y, Ishikawa T, Takahashi S, Takano H, Noda T, Sekiguchi M.

Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5116-20.

35.

p16INK4 gene mutations are relatively frequent in ampullary carcinomas.

Imai Y, Tsurutani N, Oda H, Nakatsuru Y, Inoue T, Ishikawa T.

Jpn J Cancer Res. 1997 Oct;88(10):941-6.

36.

Frequent somatic mutations of the APC and p53 genes in sporadic ampullary carcinomas.

Imai Y, Oda H, Tsurutani N, Nakatsuru Y, Inoue T, Ishikawa T.

Jpn J Cancer Res. 1997 Sep;88(9):846-54.

37.

High incidence of nitrosamine-induced tumorigenesis in mice lacking DNA repair methyltransferase.

Iwakuma T, Sakumi K, Nakatsuru Y, Kawate H, Igarashi H, Shiraishi A, Tsuzuki T, Ishikawa T, Sekiguchi M.

Carcinogenesis. 1997 Aug;18(8):1631-5.

PMID:
9276640
38.

Loss of p53 is an early event in induction of brain tumors in mice by transplacental carcinogen exposure.

Oda H, Zhang S, Tsurutani N, Shimizu S, Nakatsuru Y, Aizawa S, Ishikawa T.

Cancer Res. 1997 Feb 15;57(4):646-50.

39.

Mutations of the Ki-ras, p53 and APC genes in adenocarcinomas of the human small intestine.

Arai M, Shimizu S, Imai Y, Nakatsuru Y, Oda H, Oohara T, Ishikawa T.

Int J Cancer. 1997 Feb 7;70(4):390-5.

40.
41.

Somatic mutations of the APC gene in sporadic hepatoblastomas.

Oda H, Imai Y, Nakatsuru Y, Hata J, Ishikawa T.

Cancer Res. 1996 Jul 15;56(14):3320-3.

42.

Detection of ultraviolet photoproducts in mouse skin exposed to natural sunlight.

Qin X, Zhang S, Zarkovic M, Nakatsuru Y, Shimizu S, Yamazaki Y, Oda H, Nikaido O, Ishikawa T.

Jpn J Cancer Res. 1996 Jul;87(7):685-90.

43.

Quantitative detection of ultraviolet light-induced photoproducts in mouse skin by immunohistochemistry.

Qin X, Zhang S, Oda H, Nakatsuru Y, Shimizu S, Yamazaki Y, Nikaido O, Ishikawa T.

Jpn J Cancer Res. 1995 Nov;86(11):1041-8.

44.

Inhibitory effect of probucol on benzo[a]pyrene induced lung tumorigenesis.

Zarkovic M, Qin X, Nakatsuru Y, Zhang S, Yamazaki Y, Oda H, Ishikawa T, Ishikawa T.

Carcinogenesis. 1995 Oct;16(10):2599-601.

PMID:
7586173
45.

Inhibitory effect of probucol on nephrotoxicity induced by ferric nitrilotriacetate (Fe-NTA) in rats.

Qin X, Zhang S, Zarkovic M, Yamazaki Y, Oda H, Nakatsuru Y, Ishikawa T, Ishikawa T.

Carcinogenesis. 1995 Oct;16(10):2549-52.

PMID:
7586165
46.
47.

High incidence of ultraviolet-B-or chemical-carcinogen-induced skin tumours in mice lacking the xeroderma pigmentosum group A gene.

Nakane H, Takeuchi S, Yuba S, Saijo M, Nakatsu Y, Murai H, Nakatsuru Y, Ishikawa T, Hirota S, Kitamura Y, et al.

Nature. 1995 Sep 14;377(6545):165-8.

PMID:
7675085
48.

A mutational hot spot in the p53 gene is associated with hepatoblastomas.

Oda H, Nakatsuru Y, Imai Y, Sugimura H, Ishikawa T.

Int J Cancer. 1995 Mar 16;60(6):786-90.

PMID:
7896446
50.

Detection of active UV-photoproduct repair in monkey skin in vivo by quantitative immunohistochemistry.

Qin X, Zhang S, Nakatsuru Y, Oda H, Yamazaki Y, Suzuki T, Nikaido O, Ishikawa T.

Cancer Lett. 1994 Aug 15;83(1-2):291-8.

PMID:
8062226

Supplemental Content

Loading ...
Support Center