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Items: 1 to 50 of 165

1.

Possible involvement of normalized Pin1 expression level and AMPK activation in the molecular mechanisms underlying renal protective effects of SGLT2 inhibitors in mice.

Inoue MK, Matsunaga Y, Nakatsu Y, Yamamotoya T, Ueda K, Kushiyama A, Sakoda H, Fujishiro M, Ono H, Iwashita M, Sano T, Nishimura F, Morii K, Sasaki K, Masaki T, Asano T.

Diabetol Metab Syndr. 2019 Jul 22;11:57. doi: 10.1186/s13098-019-0454-6. eCollection 2019.

2.

Corrigendum to "Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing" [Exp. Cell Res. 377 (2019) 24-35].

Hayashida G, Shioi S, Hidaka K, Fujikane R, Hidaka M, Tsurimoto T, Tsuzuki T, Oda S, Nakatsu Y.

Exp Cell Res. 2019 Jul 25:111432. doi: 10.1016/j.yexcr.2019.05.013. [Epub ahead of print] No abstract available.

PMID:
31351707
3.

Linked Color Imaging and the Kyoto Classification of Gastritis: Evaluation of Visibility and Inter-Rater Reliability.

Takeda T, Asaoka D, Nojiri S, Nishiyama M, Ikeda A, Yatagai N, Ishizuka K, Hiromoto T, Okubo S, Suzuki M, Nakajima A, Nakatsu Y, Komori H, Akazawa Y, Nakagawa Y, Izumi K, Matsumoto K, Ueyama H, Sasaki H, Shimada Y, Matsumoto K, Osada T, Hojo M, Kato M, Nagahara A.

Digestion. 2019 Jul 12:1-10. doi: 10.1159/000501534. [Epub ahead of print]

PMID:
31302654
4.

Quorum-dependent expression of rsmX and rsmY, small non-coding RNAs, in Pseudomonas syringae.

Nakatsu Y, Matsui H, Yamamoto M, Noutoshi Y, Toyoda K, Ichinose Y.

Microbiol Res. 2019 Jun - Aug;223-225:72-78. doi: 10.1016/j.micres.2019.04.004. Epub 2019 Apr 12.

PMID:
31178054
5.

Photocontrollable mononegaviruses.

Tahara M, Takishima Y, Miyamoto S, Nakatsu Y, Someya K, Sato M, Tani K, Takeda M.

Proc Natl Acad Sci U S A. 2019 Jun 11;116(24):11587-11589. doi: 10.1073/pnas.1906531116. Epub 2019 May 28.

6.

The R2TP complex regulates paramyxovirus RNA synthesis.

Katoh H, Sekizuka T, Nakatsu Y, Nakagawa R, Nao N, Sakata M, Kato F, Kuroda M, Kidokoro M, Takeda M.

PLoS Pathog. 2019 May 23;15(5):e1007749. doi: 10.1371/journal.ppat.1007749. eCollection 2019 May.

7.

Consensus and variations in cell line specificity among human metapneumovirus strains.

Nao N, Sato K, Yamagishi J, Tahara M, Nakatsu Y, Seki F, Katoh H, Ohnuma A, Shirogane Y, Hayashi M, Suzuki T, Kikuta H, Nishimura H, Takeda M.

PLoS One. 2019 Apr 23;14(4):e0215822. doi: 10.1371/journal.pone.0215822. eCollection 2019.

8.

Prolyl isomerase Pin1 binds to and stabilizes acetyl CoA carboxylase 1 protein, thereby supporting cancer cell proliferation.

Ueda K, Nakatsu Y, Yamamotoya T, Ono H, Inoue Y, Inoue MK, Mizuno Y, Matsunaga Y, Kushiyama A, Sakoda H, Fujishiro M, Takahashi SI, Matsubara A, Asano T.

Oncotarget. 2019 Feb 26;10(17):1637-1648. doi: 10.18632/oncotarget.26691. eCollection 2019 Feb 26.

9.

Prolyl Isomerase Pin1 Suppresses Thermogenic Programs in Adipocytes by Promoting Degradation of Transcriptional Co-activator PRDM16.

Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue MK, Mizuno Y, Nakanishi M, Sano T, Yamawaki Y, Kushiyama A, Sakoda H, Fujishiro M, Ryo A, Ono H, Minamino T, Takahashi SI, Ohno H, Yoneda M, Takahashi K, Ishihara H, Katagiri H, Nishimura F, Kanematsu T, Yamada T, Asano T.

Cell Rep. 2019 Mar 19;26(12):3221-3230.e3. doi: 10.1016/j.celrep.2019.02.066.

10.

Differential genomic destabilisation in human cells with pathogenic MSH2 mutations introduced by genome editing.

Hayashida G, Shioi S, Hidaka K, Fujikane R, Hidaka M, Tsurimoto T, Tsuzuki T, Oda S, Nakatsu Y.

Exp Cell Res. 2019 Apr 15;377(1-2):24-35. doi: 10.1016/j.yexcr.2019.02.020. Epub 2019 Feb 22. Erratum in: Exp Cell Res. 2019 Jul 25;:111432.

11.

The Xanthine Oxidase Inhibitor Febuxostat Suppresses the Progression of IgA Nephropathy, Possibly via Its Anti-Inflammatory and Anti-Fibrotic Effects in the gddY Mouse Model.

Inoue MK, Yamamotoya T, Nakatsu Y, Ueda K, Inoue Y, Matsunaga Y, Sakoda H, Fujishiro M, Ono H, Morii K, Sasaki K, Masaki T, Suzuki Y, Asano T, Kushiyama A.

Int J Mol Sci. 2018 Dec 10;19(12). pii: E3967. doi: 10.3390/ijms19123967.

12.

Development of Pin1 inhibitors and their potential as therapeutic agents.

Nakatsu Y, Matsunaga Y, Ueda K, Yamamotoya T, Inoue Y, Inoue MK, Mizuno Y, Kushiyama A, Ono H, Fujishiro M, Ito H, Okabe T, Asano T.

Curr Med Chem. 2018 Nov 5. doi: 10.2174/0929867325666181105120911. [Epub ahead of print]

PMID:
30394205
13.

Roles of Gut-Derived Secretory Factors in the Pathogenesis of Non-Alcoholic Fatty Liver Disease and Their Possible Clinical Applications.

Okubo H, Kushiyama A, Nakatsu Y, Yamamotoya T, Matsunaga Y, Fujishiro M, Sakoda H, Ohno H, Yoneda M, Asano T.

Int J Mol Sci. 2018 Oct 8;19(10). pii: E3064. doi: 10.3390/ijms19103064. Review.

14.

Protective Effect of Sex Hormone-Binding Globulin against Metabolic Syndrome: In Vitro Evidence Showing Anti-Inflammatory and Lipolytic Effects on Adipocytes and Macrophages.

Yamazaki H, Kushiyama A, Sakoda H, Fujishiro M, Yamamotoya T, Nakatsu Y, Kikuchi T, Kaneko S, Tanaka H, Asano T.

Mediators Inflamm. 2018 Jun 25;2018:3062319. doi: 10.1155/2018/3062319. eCollection 2018.

15.

Budding Uninhibited by Benzimidazole-1 Insufficiency Prevents Acute Renal Failure in Severe Sepsis by Maintaining Anticoagulant Functions of Vascular Endothelial Cells.

Matsubara Y, Matsumoto T, Yoshiya K, Yoshida A, Ikeda S, Furuyama T, Nakatsu Y, Tsuzuki T, Nomura M, Maehara Y.

Shock. 2019 Mar;51(3):364-371. doi: 10.1097/SHK.0000000000001147.

PMID:
29608549
16.

Effects of mismatches distant from the target position on gene correction with a 5'-tailed duplex.

Suzuki T, Yanai Y, Nishigaki N, Nakatsu Y, Tsuzuki T, Kamiya H.

J Biosci Bioeng. 2018 May;125(5):619-623. doi: 10.1016/j.jbiosc.2017.12.017. Epub 2018 Feb 1.

PMID:
29361419
17.

Effect of acetaminophen on osteoblastic differentiation and migration of MC3T3-E1 cells.

Nakatsu Y, Nakagawa F, Higashi S, Ohsumi T, Shiiba S, Watanabe S, Takeuchi H.

Pharmacol Rep. 2018 Feb;70(1):29-36. doi: 10.1016/j.pharep.2017.07.006. Epub 2017 Jul 15.

PMID:
29306760
18.

Trk-fused gene (TFG) regulates pancreatic β cell mass and insulin secretory activity.

Yamamotoya T, Nakatsu Y, Kushiyama A, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Sakoda H, Fujishiro M, Ono H, Kiyonari H, Ishihara H, Asano T.

Sci Rep. 2017 Oct 12;7(1):13026. doi: 10.1038/s41598-017-13432-x.

19.

Gut Microbiota as a Therapeutic Target for Metabolic Disorders.

Okubo H, Nakatsu Y, Kushiyama A, Yamamotoya T, Matsunaga Y, Inoue MK, Fujishiro M, Sakoda H, Ohno H, Yoneda M, Ono H, Asano T.

Curr Med Chem. 2018;25(9):984-1001. doi: 10.2174/0929867324666171009121702. Review.

PMID:
28990516
20.

The SGLT2 Inhibitor Luseogliflozin Rapidly Normalizes Aortic mRNA Levels of Inflammation-Related but Not Lipid-Metabolism-Related Genes and Suppresses Atherosclerosis in Diabetic ApoE KO Mice.

Nakatsu Y, Kokubo H, Bumdelger B, Yoshizumi M, Yamamotoya T, Matsunaga Y, Ueda K, Inoue Y, Inoue MK, Fujishiro M, Kushiyama A, Ono H, Sakoda H, Asano T.

Int J Mol Sci. 2017 Aug 4;18(8). pii: E1704. doi: 10.3390/ijms18081704.

21.

The prolyl isomerase Pin1 increases β-cell proliferation and enhances insulin secretion.

Nakatsu Y, Mori K, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mitsuzaki-Miyoshi K, Sakoda H, Fujishiro M, Yamaguchi S, Kushiyama A, Ono H, Ishihara H, Asano T.

J Biol Chem. 2017 Jul 14;292(28):11886-11895. doi: 10.1074/jbc.M117.780726. Epub 2017 May 31.

22.

The SETD8/PR-Set7 Methyltransferase Functions as a Barrier to Prevent Senescence-Associated Metabolic Remodeling.

Tanaka H, Takebayashi SI, Sakamoto A, Igata T, Nakatsu Y, Saitoh N, Hino S, Nakao M.

Cell Rep. 2017 Feb 28;18(9):2148-2161. doi: 10.1016/j.celrep.2017.02.021.

23.

Reduced SHARPIN and LUBAC Formation May Contribute to CCl₄- or Acetaminophen-Induced Liver Cirrhosis in Mice.

Yamamotoya T, Nakatsu Y, Matsunaga Y, Fukushima T, Yamazaki H, Kaneko S, Fujishiro M, Kikuchi T, Kushiyama A, Tokunaga F, Asano T, Sakoda H.

Int J Mol Sci. 2017 Feb 4;18(2). pii: E326. doi: 10.3390/ijms18020326.

24.

USP15 attenuates IGF-I signaling by antagonizing Nedd4-induced IRS-2 ubiquitination.

Fukushima T, Yoshihara H, Furuta H, Hakuno F, Iemura SI, Natsume T, Nakatsu Y, Kamata H, Asano T, Komada M, Takahashi SI.

Biochem Biophys Res Commun. 2017 Mar 11;484(3):522-528. doi: 10.1016/j.bbrc.2017.01.101. Epub 2017 Jan 23.

PMID:
28126338
25.

Role of Uric Acid Metabolism-Related Inflammation in the Pathogenesis of Metabolic Syndrome Components Such as Atherosclerosis and Nonalcoholic Steatohepatitis.

Kushiyama A, Nakatsu Y, Matsunaga Y, Yamamotoya T, Mori K, Ueda K, Inoue Y, Sakoda H, Fujishiro M, Ono H, Asano T.

Mediators Inflamm. 2016;2016:8603164. doi: 10.1155/2016/8603164. Epub 2016 Dec 14. Review.

26.

Molecular cloning, polymorphism, and functional activity of the bovine and water buffalo Mx2 gene promoter region.

Babiker HA, Saito T, Nakatsu Y, Takasuga S, Morita M, Sugimoto Y, Ueda J, Watanabe T.

Springerplus. 2016 Dec 22;5(1):2109. doi: 10.1186/s40064-016-3729-5. eCollection 2016.

27.

Heat Shock Protein 90 Ensures Efficient Mumps Virus Replication by Assisting with Viral Polymerase Complex Formation.

Katoh H, Kubota T, Nakatsu Y, Tahara M, Kidokoro M, Takeda M.

J Virol. 2017 Feb 28;91(6). pii: e02220-16. doi: 10.1128/JVI.02220-16. Print 2017 Mar 15.

28.

BUBR1 Insufficiency in Mice Increases their Sensitivity to Oxidative Stress.

Matsuda D, Matsumoto T, Honma K, Ikawa-Yoshida A, Onimaru M, Furuyama T, Nakatsu Y, Tsuzuki T, Maehara Y.

In Vivo. 2016 11-12;30(6):769-776.

PMID:
27815460
29.

Celecoxib and 2,5-dimethylcelecoxib inhibit intestinal cancer growth by suppressing the Wnt/β-catenin signaling pathway.

Egashira I, Takahashi-Yanaga F, Nishida R, Arioka M, Igawa K, Tomooka K, Nakatsu Y, Tsuzuki T, Nakabeppu Y, Kitazono T, Sasaguri T.

Cancer Sci. 2017 Jan;108(1):108-115. doi: 10.1111/cas.13106. Epub 2016 Dec 1.

30.

Physiological and Pathogenic Roles of Prolyl Isomerase Pin1 in Metabolic Regulations via Multiple Signal Transduction Pathway Modulations.

Nakatsu Y, Matsunaga Y, Yamamotoya T, Ueda K, Inoue Y, Mori K, Sakoda H, Fujishiro M, Ono H, Kushiyama A, Asano T.

Int J Mol Sci. 2016 Sep 7;17(9). pii: E1495. doi: 10.3390/ijms17091495. Review.

31.

Coordination of Cellular Dynamics Contributes to Tooth Epithelium Deformations.

Morita R, Kihira M, Nakatsu Y, Nomoto Y, Ogawa M, Ohashi K, Mizuno K, Tachikawa T, Ishimoto Y, Morishita Y, Tsuji T.

PLoS One. 2016 Sep 2;11(9):e0161336. doi: 10.1371/journal.pone.0161336. eCollection 2016.

32.

BubR1 Insufficiency Impairs Liver Regeneration in Aged Mice after Hepatectomy through Intercalated Disc Abnormality.

Ikawa-Yoshida A, Matsumoto T, Okano S, Aoyagi Y, Matsubara Y, Furuyama T, Nakatsu Y, Tsuzuki T, Onimaru M, Ohkusa T, Nomura M, Maehara Y.

Sci Rep. 2016 Aug 26;6:32399. doi: 10.1038/srep32399.

33.

Insertion and Deletion Mismatches Distant from the Target Position Improve Gene Correction with a Tailed Duplex.

Kamiya H, Nishigaki N, Ikeda A, Yukawa S, Morita Y, Nakatsu Y, Tsuzuki T, Harashima H.

Nucleosides Nucleotides Nucleic Acids. 2016 Jul 2;35(7):379-88. doi: 10.1080/15257770.2016.1163384. Epub 2016 Jun 2.

34.

Involvement of resistin-like molecule β in the development of methionine-choline deficient diet-induced non-alcoholic steatohepatitis in mice.

Okubo H, Kushiyama A, Sakoda H, Nakatsu Y, Iizuka M, Taki N, Fujishiro M, Fukushima T, Kamata H, Nagamachi A, Inaba T, Nishimura F, Katagiri H, Asahara T, Yoshida Y, Chonan O, Encinas J, Asano T.

Sci Rep. 2016 Jan 28;6:20157. doi: 10.1038/srep20157.

35.

Treatment with the SGLT2 inhibitor luseogliflozin improves nonalcoholic steatohepatitis in a rodent model with diabetes mellitus.

Qiang S, Nakatsu Y, Seno Y, Fujishiro M, Sakoda H, Kushiyama A, Mori K, Matsunaga Y, Yamamotoya T, Kamata H, Asano T.

Diabetol Metab Syndr. 2015 Nov 19;7:104. doi: 10.1186/s13098-015-0102-8. eCollection 2015.

36.

Mumps Virus Is Released from the Apical Surface of Polarized Epithelial Cells, and the Release Is Facilitated by a Rab11-Mediated Transport System.

Katoh H, Nakatsu Y, Kubota T, Sakata M, Takeda M, Kidokoro M.

J Virol. 2015 Dec;89(23):12026-34. doi: 10.1128/JVI.02048-15. Epub 2015 Sep 16.

37.

Combination of Zinc and All-Trans Retinoic Acid Promotes Protection against Listeria monocytogenes Infection.

Castillo Y, Tachibana M, Nakatsu Y, Watanabe K, Shimizu T, Watarai M.

PLoS One. 2015 Sep 9;10(9):e0137463. doi: 10.1371/journal.pone.0137463. eCollection 2015.

38.

BTK gene targeting by homologous recombination using a helper-dependent adenovirus/adeno-associated virus hybrid vector.

Yamamoto H, Ishimura M, Ochiai M, Takada H, Kusuhara K, Nakatsu Y, Tsuzuki T, Mitani K, Hara T.

Gene Ther. 2016 Feb;23(2):205-13. doi: 10.1038/gt.2015.91. Epub 2015 Aug 17.

PMID:
26280081
39.

Prolyl isomerase Pin1 negatively regulates AMP-activated protein kinase (AMPK) by associating with the CBS domain in the γ subunit.

Nakatsu Y, Iwashita M, Sakoda H, Ono H, Nagata K, Matsunaga Y, Fukushima T, Fujishiro M, Kushiyama A, Kamata H, Takahashi S, Katagiri H, Honda H, Kiyonari H, Uchida T, Asano T.

J Biol Chem. 2015 Oct 2;290(40):24255-66. doi: 10.1074/jbc.M115.658559. Epub 2015 Aug 14.

40.

Distinct Time Course of the Decrease in Hepatic AMP-Activated Protein Kinase and Akt Phosphorylation in Mice Fed a High Fat Diet.

Shiwa M, Yoneda M, Okubo H, Ohno H, Kobuke K, Monzen Y, Kishimoto R, Nakatsu Y, Asano T, Kohno N.

PLoS One. 2015 Aug 12;10(8):e0135554. doi: 10.1371/journal.pone.0135554. eCollection 2015.

41.

LUBAC Formation Is Impaired in the Livers of Mice with MCD-Dependent Nonalcoholic Steatohepatitis.

Matsunaga Y, Nakatsu Y, Fukushima T, Okubo H, Iwashita M, Sakoda H, Fujishiro M, Yamamotoya T, Kushiyama A, Takahashi S, Tsuchiya Y, Kamata H, Tokunaga F, Iwai K, Asano T.

Mediators Inflamm. 2015;2015:125380. doi: 10.1155/2015/125380. Epub 2015 Jun 10.

42.

High-fat diet feeding significantly attenuates anagliptin-induced regeneration of islets of Langerhans in streptozotocin-induced diabetic mice.

Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Nishimura F, Asano T.

Diabetol Metab Syndr. 2015 Jun 2;7:50. doi: 10.1186/s13098-015-0047-y. eCollection 2015.

43.

Pin1 Inhibitor Juglone Exerts Anti-Oncogenic Effects on LNCaP and DU145 Cells despite the Patterns of Gene Regulation by Pin1 Differing between These Cell Lines.

Kanaoka R, Kushiyama A, Seno Y, Nakatsu Y, Matsunaga Y, Fukushima T, Tsuchiya Y, Sakoda H, Fujishiro M, Yamamotoya T, Kamata H, Matsubara A, Asano T.

PLoS One. 2015 Jun 3;10(6):e0127467. doi: 10.1371/journal.pone.0127467. eCollection 2015.

44.

DPP-IV inhibitor anagliptin exerts anti-inflammatory effects on macrophages, adipocytes, and mouse livers by suppressing NF-κB activation.

Shinjo T, Nakatsu Y, Iwashita M, Sano T, Sakoda H, Ishihara H, Kushiyama A, Fujishiro M, Fukushima T, Tsuchiya Y, Kamata H, Nishimura F, Asano T.

Am J Physiol Endocrinol Metab. 2015 Aug 1;309(3):E214-23. doi: 10.1152/ajpendo.00553.2014. Epub 2015 May 26.

45.

Retinoblastoma protein promotes oxidative phosphorylation through upregulation of glycolytic genes in oncogene-induced senescent cells.

Takebayashi S, Tanaka H, Hino S, Nakatsu Y, Igata T, Sakamoto A, Narita M, Nakao M.

Aging Cell. 2015 Aug;14(4):689-97. doi: 10.1111/acel.12351. Epub 2015 May 25.

46.

The xanthine oxidase inhibitor febuxostat suppresses development of nonalcoholic steatohepatitis in a rodent model.

Nakatsu Y, Seno Y, Kushiyama A, Sakoda H, Fujishiro M, Katasako A, Mori K, Matsunaga Y, Fukushima T, Kanaoka R, Yamamotoya T, Kamata H, Asano T.

Am J Physiol Gastrointest Liver Physiol. 2015 Jul 1;309(1):G42-51. doi: 10.1152/ajpgi.00443.2014. Epub 2015 May 21.

47.

Differentiation-inducing factor-3 inhibits intestinal tumor growth in vitro and in vivo.

Kubokura N, Takahashi-Yanaga F, Arioka M, Yoshihara T, Igawa K, Tomooka K, Morimoto S, Nakatsu Y, Tsuzuki T, Nakabeppu Y, Matsumoto T, Kitazono T, Sasaguri T.

J Pharmacol Sci. 2015 Apr;127(4):446-55. doi: 10.1016/j.jphs.2015.03.005. Epub 2015 Mar 24.

48.

Nedd4-induced monoubiquitination of IRS-2 enhances IGF signalling and mitogenic activity.

Fukushima T, Yoshihara H, Furuta H, Kamei H, Hakuno F, Luan J, Duan C, Saeki Y, Tanaka K, Iemura S, Natsume T, Chida K, Nakatsu Y, Kamata H, Asano T, Takahashi S.

Nat Commun. 2015 Apr 16;6:6780. doi: 10.1038/ncomms7780.

PMID:
25879670
49.

Stereotaxic atlas of the goat brain for an accurate approach to the hypothalamic nuclei.

Sunagawa K, Nagamine I, Fujino T, Nakatsu Y, Hikosaka K.

Physiol Behav. 2015 Jun 1;145:91-105. doi: 10.1016/j.physbeh.2015.03.030. Epub 2015 Mar 24.

PMID:
25817539
50.

UV-induced mutations in epidermal cells of mice defective in DNA polymerase η and/or ι.

Kanao R, Yokoi M, Ohkumo T, Sakurai Y, Dotsu K, Kura S, Nakatsu Y, Tsuzuki T, Masutani C, Hanaoka F.

DNA Repair (Amst). 2015 May;29:139-46. doi: 10.1016/j.dnarep.2015.02.006. Epub 2015 Feb 16.

PMID:
25733082

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