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Glucose Depletion Enhances the Stem Cell Phenotype and Gemcitabine Resistance of Cholangiocarcinoma Organoids through AKT Phosphorylation and Reactive Oxygen Species.
Yoshikawa N, Saito Y, Manabe H, Nakaoka T, Uchida R, Furukawa R, Muramatsu T, Sugiyama Y, Kimura M, Saito H.
Cancers (Basel). 2019 Dec 11;11(12). pii: E1993. doi: 10.3390/cancers11121993.
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Effects of timing of acute catechin-rich green tea ingestion on postprandial glucose metabolism in healthy men.
Takahashi M, Ozaki M, Miyashita M, Fukazawa M, Nakaoka T, Wakisaka T, Matsui Y, Hibi M, Osaki N, Shibata S.
J Nutr Biochem. 2019 Nov;73:108221. doi: 10.1016/j.jnutbio.2019.108221. Epub 2019 Aug 15.
Pulmonary Langerhans cell histiocytosis with thyroid involvement manifesting as recurrent bilateral pneumothorax and tension bullae in a 3-year-old child.
Yokoyama S, Nakaoka T, Fukao D, Yokoyama K, Hara S, Hamahata K, Yoshida A.
Int J Surg Case Rep. 2019;60:239-243. doi: 10.1016/j.ijscr.2019.06.027. Epub 2019 Jun 20.
Reply to: Do Calcium-Based Phosphate Binders Accelerate or Prevent Coronary Artery Calcification in Dialysis Patients?
Nishizawa Y, Higuchi C, Nakaoka T, Omori H, Ogawa T, Sakura H, Nitta K.
Ther Apher Dial. 2019 Jun;23(3):301. doi: 10.1111/1744-9987.12812. Epub 2019 May 23. No abstract available.
Erratum: Publisher Correction: Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging.
Uchida R, Saito Y, Nogami K, Kajiyama Y, Suzuki Y, Kawase Y, Nakaoka T, Muramatsu T, Kimura M, Saito H.
NPJ Aging Mech Dis. 2019 Mar 7;5:5. doi: 10.1038/s41514-019-0035-9. eCollection 2019.
The effect of night shift work on the expression of clock genes in beard hair follicle cells.
Hattammaru M, Tahara Y, Kikuchi T, Okajima K, Konishi K, Nakajima S, Sato K, Otsuka K, Sakura H, Shibata S, Nakaoka T.
Sleep Med. 2019 Apr;56:164-170. doi: 10.1016/j.sleep.2019.01.005. Epub 2019 Jan 17.
Epigenetic silencing of Lgr5 induces senescence of intestinal epithelial organoids during the process of aging.
NPJ Aging Mech Dis. 2018 Dec 1;5:1. doi: 10.1038/s41514-018-0031-5. eCollection 2019. Erratum in: NPJ Aging Mech Dis. 2019 Mar 7;5:5.
Chronotype and social jetlag influence human circadian clock gene expression.
Takahashi M, Tahara Y, Tsubosaka M, Fukazawa M, Ozaki M, Iwakami T, Nakaoka T, Shibata S.
Sci Rep. 2018 Jul 5;8(1):10152. doi: 10.1038/s41598-018-28616-2.
A randomized, double-blind and placebo-controlled crossover trial on the effect of l-ornithine ingestion on the human circadian clock.
Fukuda T, Haraguchi A, Takahashi M, Nakaoka T, Fukazawa M, Okubo J, Ozaki M, Kanatome A, Ohya R, Miura Y, Obara K, Shibata S.
Chronobiol Int. 2018 Sep;35(10):1445-1455. doi: 10.1080/07420528.2018.1490315. Epub 2018 Jul 3.
Compositional Analysis of Coronary Artery Calcification in Dialysis Patients in vivo by Dual-Energy Computed Tomography Angiography.
Ther Apher Dial. 2018 Aug;22(4):365-370. doi: 10.1111/1744-9987.12662. Epub 2018 Mar 30.
A Clinical Quantitative Evaluation of Hepatobiliary Transport of [11C]Dehydropravastatin in Humans Using Positron Emission Tomography.
Kaneko K, Tanaka M, Ishii A, Katayama Y, Nakaoka T, Irie S, Kawahata H, Yamanaga T, Wada Y, Miyake T, Toshimoto K, Maeda K, Cui Y, Enomoto M, Kawamura E, Kawada N, Kawabe J, Shiomi S, Kusuhara H, Sugiyama Y, Watanabe Y.
Drug Metab Dispos. 2018 May;46(5):719-728. doi: 10.1124/dmd.118.080408. Epub 2018 Mar 19.
Induction of differentiation of intrahepatic cholangiocarcinoma cells to functional hepatocytes using an organoid culture system.
Saito Y, Nakaoka T, Muramatsu T, Ojima H, Sukeda A, Sugiyama Y, Uchida R, Furukawa R, Kitahara A, Sato T, Kanai Y, Saito H.
Sci Rep. 2018 Feb 12;8(1):2821. doi: 10.1038/s41598-018-21121-6.
Gut microbiota-mediated generation of saturated fatty acids elicits inflammation in the liver in murine high-fat diet-induced steatohepatitis.
Yamada S, Kamada N, Amiya T, Nakamoto N, Nakaoka T, Kimura M, Saito Y, Ejima C, Kanai T, Saito H.
BMC Gastroenterol. 2017 Nov 29;17(1):136. doi: 10.1186/s12876-017-0689-3.
Ultrasound-guided hydrostatic enema for meconium obstruction in extremely low birth weight infants: a preliminary report.
Nakaoka T, Nishimoto S, Tsukazaki Y, Santo K, Higashio A, Kamiyama M, Uehara S, Yoneda A, Tanaka Y, Ichiba H.
Pediatr Surg Int. 2017 Sep;33(9):1019-1022. doi: 10.1007/s00383-017-4129-9. Epub 2017 Jul 25.
Aberrant DNA Methylation as a Biomarker and a Therapeutic Target of Cholangiocarcinoma.
Nakaoka T, Saito Y, Saito H.
Int J Mol Sci. 2017 May 23;18(6). pii: E1111. doi: 10.3390/ijms18061111. Review.
Clinical application of effective atomic number for classifying non-calcified coronary plaques by dual-energy computed tomography.
Nakajima S, Ito H, Mitsuhashi T, Kubo Y, Matsui K, Tanaka I, Fukui R, Omori H, Nakaoka T, Sakura H, Ueno E, Machida H.
Atherosclerosis. 2017 Jun;261:138-143. doi: 10.1016/j.atherosclerosis.2017.03.025. Epub 2017 Mar 21.
Deep sequencing of the prothoracic gland transcriptome reveals new players in insect ecdysteroidogenesis.
Nakaoka T, Iga M, Yamada T, Koujima I, Takeshima M, Zhou X, Suzuki Y, Ogihara MH, Kataoka H.
PLoS One. 2017 Mar 3;12(3):e0172951. doi: 10.1371/journal.pone.0172951. eCollection 2017.
Identification of ecdysteroidogenic enzyme genes and their expression during pupal diapause in the cabbage armyworm, Mamestra brassicae.
Ogihara MH, Ikeda H, Yamada N, Hikiba J, Nakaoka T, Fujimoto Y, Suzuki Y, Saito K, Mizoguchi A, Kataoka H.
Insect Mol Biol. 2017 Jun;26(3):286-297. doi: 10.1111/imb.12291. Epub 2017 Jan 25.
Cluster microRNAs miR-194 and miR-215 suppress the tumorigenicity of intestinal tumor organoids.
Nakaoka T, Saito Y, Shimamoto Y, Muramatsu T, Kimura M, Kanai Y, Saito H.
Cancer Sci. 2017 Apr;108(4):678-684. doi: 10.1111/cas.13165. Epub 2017 Apr 19.
A New Molecular Mechanism Underlying the Antitumor Effect of DNA Methylation Inhibitors via an Antiviral Immune Response.
Saito Y, Nakaoka T, Saito H.
Adv Protein Chem Struct Biol. 2017;106:227-242. doi: 10.1016/bs.apcsb.2016.08.005. Epub 2016 Sep 23. Review.
Positive association between physical activity and PER3 expression in older adults.
Takahashi M, Haraguchi A, Tahara Y, Aoki N, Fukazawa M, Tanisawa K, Ito T, Nakaoka T, Higuchi M, Shibata S.
Sci Rep. 2017 Jan 3;7:39771. doi: 10.1038/srep39771.
Implantable central venous access device in infants: Long-term results.
Ohno K, Nakaoka T, Takama Y, Higashio A, Santo K, Yoneda A.
Pediatr Int. 2016 Oct;58(10):1027-1031. doi: 10.1111/ped.12945. Epub 2016 Sep 8.
Inhibition of Nox1 induces apoptosis by attenuating the AKT signaling pathway in oral squamous cell carcinoma cell lines.
Ito K, Ota A, Ono T, Nakaoka T, Wahiduzzaman M, Karnan S, Konishi H, Furuhashi A, Hayashi T, Yamada Y, Hosokawa Y, Kazaoka Y.
Oncol Rep. 2016 Nov;36(5):2991-2998. doi: 10.3892/or.2016.5068. Epub 2016 Sep 5.
Inhibition of DNA Methylation Suppresses Intestinal Tumor Organoids by Inducing an Anti-Viral Response.
Saito Y, Nakaoka T, Sakai K, Muramatsu T, Toshimitsu K, Kimura M, Kanai T, Sato T, Saito H.
Sci Rep. 2016 May 4;6:25311. doi: 10.1038/srep25311.
Exploration of Antiemetics for Osteoporosis Therapy-Induced Nausea and Vomiting Using PET Molecular Imaging Analysis to Gastrointestinal Pharmacokinetics.
Shingaki T, Katayama Y, Nakaoka T, Takashima T, Onoe K, Okauchi T, Hayashinaka E, Wada Y, Cui Y, Watanabe Y.
Pharm Res. 2016 May;33(5):1235-48. doi: 10.1007/s11095-016-1868-6. Epub 2016 Feb 11.
Visualization of drug translocation in the nasal cavity and pharmacokinetic analysis on nasal drug absorption using positron emission tomography in the rat.
Shingaki T, Katayama Y, Nakaoka T, Irie S, Onoe K, Okauchi T, Hayashinaka E, Yamaguchi M, Tanki N, Ose T, Hayashi T, Wada Y, Furubayashi T, Cui Y, Sakane T, Watanabe Y.
Eur J Pharm Biopharm. 2016 Feb;99:45-53. doi: 10.1016/j.ejpb.2015.11.014. Epub 2015 Nov 27.
microRNA-34a as a Therapeutic Agent against Human Cancer.
J Clin Med. 2015 Nov 16;4(11):1951-9. doi: 10.3390/jcm4111951. Review.
Early Detection and Treatment of Neuroblastic Tumor with Opsoclonus-Myoclonus Syndrome Improve Neurological Outcome: A Review of Five Cases at a Single Institution in Japan.
Takama Y, Yoneda A, Nakamura T, Nakaoka T, Higashio A, Santo K, Kuki I, Kawawaki H, Tomiwa K, Hara J.
Eur J Pediatr Surg. 2016 Feb;26(1):54-9. doi: 10.1055/s-0035-1564714. Epub 2015 Sep 26.
Depression and Altitude: Cross-Sectional Community-Based Study Among Elderly High-Altitude Residents in the Himalayan Regions.
Ishikawa M, Yamanaka G, Yamamoto N, Nakaoka T, Okumiya K, Matsubayashi K, Otsuka K, Sakura H.
Cult Med Psychiatry. 2016 Mar;40(1):1-11. doi: 10.1007/s11013-015-9462-7.
Amphiphilic Organic-Inorganic Hybrid Zeotype Aluminosilicate like a Nanoporous Crystallized Langmuir-Blodgett Film.
Ikeda T, Hiyoshi N, Matsuura S, Kodaira T, Nakaoka T, Irisa A, Kawano M, Yamamoto K.
Angew Chem Int Ed Engl. 2015 Jun 26;54(27):7994-8. doi: 10.1002/anie.201503661. Epub 2015 May 27.
Plumbagin suppresses tumor cell growth in oral squamous cell carcinoma cell lines.
Ono T, Ota A, Ito K, Nakaoka T, Karnan S, Konishi H, Furuhashi A, Hayashi T, Yamada Y, Hosokawa Y, Kazaoka Y.
Oral Dis. 2015 May;21(4):501-11. doi: 10.1111/odi.12310. Epub 2015 Jan 29.
Analysis of coronary arterial calcification components with coronary CT angiography using single-source dual-energy CT with fast tube voltage switching.
Matsui K, Machida H, Mitsuhashi T, Omori H, Nakaoka T, Sakura H, Ueno E.
Int J Cardiovasc Imaging. 2015 Mar;31(3):639-47. doi: 10.1007/s10554-014-0574-x. Epub 2014 Nov 19.
Vasodilatation of multiple cerebral arteries in early stage of stroke-like episode with MELAS.
Minobe S, Matsuda A, Mitsuhashi T, Ishikawa M, Nishimura Y, Shibata K, Ito E, Goto Y, Nakaoka T, Sakura H.
J Clin Neurosci. 2015 Feb;22(2):407-8. doi: 10.1016/j.jocn.2014.05.021. Epub 2014 Aug 12.
Pigment dispersing factor regulates ecdysone biosynthesis via bombyx neuropeptide G protein coupled receptor-B2 in the prothoracic glands of Bombyx mori.
Iga M, Nakaoka T, Suzuki Y, Kataoka H.
PLoS One. 2014 Jul 29;9(7):e103239. doi: 10.1371/journal.pone.0103239. eCollection 2014.
Combined arsenic trioxide-cisplatin treatment enhances apoptosis in oral squamous cell carcinoma cells.
Nakaoka T, Ota A, Ono T, Karnan S, Konishi H, Furuhashi A, Ohmura Y, Yamada Y, Hosokawa Y, Kazaoka Y.
Cell Oncol (Dordr). 2014 Apr;37(2):119-29. doi: 10.1007/s13402-014-0167-7. Epub 2014 Mar 6.
Novel middle-type Kenyon cells in the honeybee brain revealed by area-preferential gene expression analysis.
Kaneko K, Ikeda T, Nagai M, Hori S, Umatani C, Tadano H, Ugajin A, Nakaoka T, Paul RK, Fujiyuki T, Shirai K, Kunieda T, Takeuchi H, Kubo T.
PLoS One. 2013 Aug 21;8(8):e71732. doi: 10.1371/journal.pone.0071732. eCollection 2013. Erratum in: PLoS One. 2013;8(11). doi:10.1371/annotation/1fa31a02-1b58-4361-98eb-5c213e5d5336.
[Association between high altitude and depression in the Himalayas and the Andes].
Ishikawa M, Yamanaka G, Nakajima S, Suwa K, Matsuda A, Nakaoka T, Okumiya K, Matsubayashi K, Otsuka K.
Nihon Ronen Igakkai Zasshi. 2013;50(3):330-4. Japanese.
Familial Currarino syndrome associated with Hirschsprung disease: two cases of a mother and daughter.
Ohno K, Nakamura T, Azuma T, Nakaoka T, Takama Y, Hayashi H, Horiike M, Zenitani M, Higashio A.
J Pediatr Surg. 2013 Jan;48(1):233-8. doi: 10.1016/j.jpedsurg.2012.10.061.
[Links between circadian system and human health].
Nakaoka T, Otsuka K.
Nihon Rinsho. 2012 Jul;70(7):1161-8. Japanese.
A highly specific and sensitive quantification analysis of the sterols in silkworm larvae by high performance liquid chromatography-atmospheric pressure chemical ionization-tandem mass spectrometry.
Igarashi F, Hikiba J, Ogihara MH, Nakaoka T, Suzuki M, Kataoka H.
Anal Biochem. 2011 Dec 15;419(2):123-32. doi: 10.1016/j.ab.2011.08.046. Epub 2011 Aug 31.
Profiling of immune-related microRNA expression in human cord blood and adult peripheral blood cells upon proinflammatory stimulation.
Takahashi N, Nakaoka T, Yamashita N.
Eur J Haematol. 2012 Jan;88(1):31-8. doi: 10.1111/j.1600-0609.2011.01707.x. Epub 2011 Nov 17.
Umbilical center insertion method for initial trocar placement in pediatric laparoscopic surgery.
Nakaoka T, Uemura S, Yoshida T, Tanimoto T, Shiokawa C, Harumoto K.
Osaka City Med J. 2010 Dec;56(2):21-6.
Gastrointestinal bleeding during anti-angiogenic peptide vaccination in combination with gemcitabine for advanced pancreatic cancer.
Nagayama H, Matsumoto K, Isoo N, Ohno H, Takahashi N, Nakaoka T, Shinozaki M, Watanabe M, Inoue Y, Nagamura F, Oyaizu N, Yamashita N.
Clin J Gastroenterol. 2010 Dec;3(6):307-17. doi: 10.1007/s12328-010-0178-5. Epub 2010 Sep 25.
Overgrowth of costal cartilage is not the etiology of pectus excavatum.
Nakaoka T, Uemura S, Yoshida T, Tanimoto T, Miyake H.
J Pediatr Surg. 2010 Oct;45(10):2015-8. doi: 10.1016/j.jpedsurg.2010.04.018.
In situ hybridization analysis of the expression of futsch, tau, and MESK2 homologues in the brain of the European honeybee (Apis mellifera L.).
Kaneko K, Hori S, Morimoto MM, Nakaoka T, Paul RK, Fujiyuki T, Shirai K, Wakamoto A, Tsuboko S, Takeuchi H, Kubo T.
PLoS One. 2010 Feb 16;5(2):e9213. doi: 10.1371/journal.pone.0009213.
Distribution of Kakugo virus and its effects on the gene expression profile in the brain of the worker honeybee Apis mellifera L.
Fujiyuki T, Matsuzaka E, Nakaoka T, Takeuchi H, Wakamoto A, Ohka S, Sekimizu K, Nomoto A, Kubo T.
J Virol. 2009 Nov;83(22):11560-8. doi: 10.1128/JVI.00519-09. Epub 2009 Sep 2.
Differential gene expression in the hypopharyngeal glands of worker honeybees (Apis mellifera L.) associated with an age-dependent role change.
Ueno T, Nakaoka T, Takeuchi H, Kubo T.
Zoolog Sci. 2009 Aug;26(8):557-63. doi: 10.2108/zsj.26.557.
Does overgrowth of costal cartilage cause pectus excavatum? A study on the lengths of ribs and costal cartilages in asymmetric patients.
Nakaoka T, Uemura S, Yano T, Nakagawa Y, Tanimoto T, Suehiro S.
J Pediatr Surg. 2009 Jul;44(7):1333-6. doi: 10.1016/j.jpedsurg.2008.09.023.
Successful reconstruction of communicating bronchopulmonary foregut malformation associated with laryngotracheoesophageal cleft.
Nakaoka T, Uemura S, Yano T, Tanimoto T, Miyake H, Kasahara S, Sano S.
J Pediatr Surg. 2009 May;44(5):e29-32. doi: 10.1016/j.jpedsurg.2009.02.061.
Iopamidol enema treatment for meconium obstruction of prematurity in extremely low-birth weight infants: a safe and effective method.
Nakaoka T, Shiokawa C, Nishihara M, Tamai H, Funato M, Uemura S.
Pediatr Surg Int. 2009 Mar;25(3):273-6. doi: 10.1007/s00383-009-2334-x. Epub 2009 Jan 30.
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