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Items: 1 to 50 of 2871

1.

Identification of Novel, Potent, and Orally Available GCN2 Inhibitors with Type I Half Binding Mode.

Fujimoto J, Kurasawa O, Takagi T, Liu X, Banno H, Kojima T, Asano Y, Nakamura A, Nambu T, Hata A, Ishii T, Sameshima T, Debori Y, Miyamoto M, Klein MG, Tjhen R, Sang BC, Levin I, Lane SW, Snell GP, Li K, Kefala G, Hoffman ID, Ding SC, Cary DR, Mizojiri R.

ACS Med Chem Lett. 2019 Sep 19;10(10):1498-1503. doi: 10.1021/acsmedchemlett.9b00400. eCollection 2019 Oct 10.

PMID:
31620240
2.

Comparison of computed tomography findings with clinical risks factors for endoscopic therapy in upper gastrointestinal bleeding cases.

Jono F, Iida H, Fujita K, Kaai M, Kanoshima K, Ohkuma K, Nonaka T, Ida T, Kusakabe A, Nakamura A, Koyama S, Nakajima A, Inamori M.

J Clin Biochem Nutr. 2019 Sep;65(2):138-145. doi: 10.3164/jcbn.18-115. Epub 2019 Jun 28.

3.

Amelioration of intracellular Ca2+ regulation by exon-45 skipping in Duchenne muscular dystrophy-induced pluripotent stem cell-derived cardiomyocytes.

Sato M, Shiba N, Miyazaki D, Shiba Y, Echigoya Y, Yokota T, Takizawa H, Aoki Y, Takeda S, Nakamura A.

Biochem Biophys Res Commun. 2019 Oct 1. pii: S0006-291X(19)31825-X. doi: 10.1016/j.bbrc.2019.09.095. [Epub ahead of print]

4.

Chemogenetic Control of Protein Anchoring to Endomembranes in Living Cells with Lipid-Tethered Small Molecules.

Nakamura A, Katahira R, Sawada S, Shinoda E, Kuwata K, Yoshii T, Tsukiji S.

Biochemistry. 2019 Oct 15. doi: 10.1021/acs.biochem.9b00807. [Epub ahead of print]

PMID:
31578861
5.

Detection of Borrelia DNA in tick species collected from vegetation and wild animals in Fukuoka, Japan.

Nakayama S, Kobayashi T, Nakamura A, Yoshitomi H, Song Y, Ashizuka Y.

Jpn J Infect Dis. 2019 Sep 30. doi: 10.7883/yoken.JJID.2019.146. [Epub ahead of print]

6.

Profiles of Physarum Microplasmodial Phosphatase Activity Crucial to Cytoplasmic Streaming and Spherule Formation.

Okada CY, Nakamura A, Ogawa K, Kohama K, Kaneko TS.

Cell Biochem Biophys. 2019 Sep 27. doi: 10.1007/s12013-019-00885-2. [Epub ahead of print]

PMID:
31562588
7.

Fragment-based discovery of the first nonpeptidyl inhibitor of an S46 family peptidase.

Sakamoto Y, Suzuki Y, Nakamura A, Watanabe Y, Sekiya M, Roppongi S, Kushibiki C, Iizuka I, Tani O, Sakashita H, Inaka K, Tanaka H, Yamada M, Ohta K, Honma N, Shida Y, Ogasawara W, Nakanishi-Matsui M, Nonaka T, Gouda H, Tanaka N.

Sci Rep. 2019 Sep 19;9(1):13587. doi: 10.1038/s41598-019-49984-3.

8.

Long term results of primary radiosurgery for vestibular schwannomas.

Johnson S, Kano H, Faramand A, Pease M, Nakamura A, Hassib M, Spencer D, Sisterson N, Faraji AH, Arai Y, Monaco E, Niranjan A, Flickinger JC, Lunsford LD.

J Neurooncol. 2019 Sep 18. doi: 10.1007/s11060-019-03290-0. [Epub ahead of print]

PMID:
31535315
9.

Hypervelocity impacts as a source of deceiving surface signatures on iron-rich asteroids.

Libourel G, Nakamura AM, Beck P, Potin S, Ganino C, Jacomet S, Ogawa R, Hasegawa S, Michel P.

Sci Adv. 2019 Aug 28;5(8):eaav3971. doi: 10.1126/sciadv.aav3971. eCollection 2019 Aug.

10.

Favourable effect of the sodium-glucose co-transporter-2 inhibitor canagliflozin plus the dipeptidyl peptidase-4 inhibitor teneligliptin in combination on glycaemic fluctuation: An open-label, prospective, randomized, parallel-group comparison trial (the CALMER study).

Cho KY, Nomoto H, Nakamura A, Kawata S, Sugawara H, Takeuchi J, Nagai S, Tsuchida K, Omori K, Yokoyama H, Manda N, Kurihara Y, Aoki S, Atsumi T, Miyoshi H.

Diabetes Obes Metab. 2019 Sep 4. doi: 10.1111/dom.13879. [Epub ahead of print]

PMID:
31486230
11.

Detection of MYD88 L265P mutation by next-generation deep sequencing in peripheral blood mononuclear cells of Waldenström's macroglobulinemia and IgM monoclonal gammopathy of undetermined significance.

Nakamura A, Ohwada C, Takeuchi M, Takeda Y, Tsukamoto S, Mimura N, Nagisa OH, Sugita Y, Tanaka H, Wakita H, Aotsuka N, Matsue K, Yokote K, Ohara O, Nakaseko C, Sakaida E.

PLoS One. 2019 Sep 4;14(9):e0221941. doi: 10.1371/journal.pone.0221941. eCollection 2019.

12.

Structural basis for the substrate recognition of aminoglycoside 7''-phosphotransferase-Ia from Streptomyces hygroscopicus.

Takenoya M, Shimamura T, Yamanaka R, Adachi Y, Ito S, Sasaki Y, Nakamura A, Yajima S.

Acta Crystallogr F Struct Biol Commun. 2019 Sep 1;75(Pt 9):599-607. doi: 10.1107/S2053230X19011105. Epub 2019 Aug 28.

PMID:
31475927
13.

Usefulness of "Nelaton Attachment" for endoscopic submucosal dissection of colorectal neoplasms.

Yoshimoto T, Takihara H, Yoshihara T, Inoue T, Ishibashi K, Uraoka M, Nakamura A, Hiramatsu S, Baba S, Abe S, Matsuura K, Hoshikawa M, Taketani R, Tanaka H, Motozato K, Tanigawa Y, Nakao E, Yokomura A, Kono M, Kagari K, Furuta A, Sunada A, Maejima K, Tsuyuguchi E, Yamasaki Y, Shishimoto T.

Endosc Int Open. 2019 Sep;7(9):E1187-E1191. doi: 10.1055/a-0961-7542. Epub 2019 Aug 29.

14.

Whole-Genome Sequence of Listeria newyorkensis, Isolated from River Water in Japan.

Ohshima C, Takahashi H, Nakamura A, Kuda T, Kimura B.

Microbiol Resour Announc. 2019 Aug 15;8(33). pii: e00488-19. doi: 10.1128/MRA.00488-19.

15.

Development of the 12-item questionnaire for quantitative assessment of depressive mixed state (DMX-12).

Shinzato H, Koda M, Nakamura A, Kondo T.

Neuropsychiatr Dis Treat. 2019 Jul 15;15:1983-1991. doi: 10.2147/NDT.S215478. eCollection 2019.

16.

Publisher Correction: Development of an immunodeficient pig model allowing long-term accommodation of artificial human vascular tubes.

Itoh M, Mukae Y, Kitsuka T, Arai K, Nakamura A, Uchihashi K, Toda S, Matsubayashi K, Oyama JI, Node K, Kami D, Gojo S, Morita S, Nishida T, Nakayama K, Kobayashi E.

Nat Commun. 2019 Aug 6;10(1):3625. doi: 10.1038/s41467-019-11555-5.

17.

Fluorescence-based discrimination of breast cancer cells by direct exposure to 5-aminolevulinic acid.

Morita M, Tanaka H, Kumamoto Y, Nakamura A, Harada Y, Ogata T, Sakaguchi K, Taguchi T, Takamatsu T.

Cancer Med. 2019 Sep;8(12):5524-5533. doi: 10.1002/cam4.2466. Epub 2019 Aug 5.

18.

Recent advances in research on isolated congenital central hypothyroidism.

Tajima T, Nakamura A, Oguma M, Yamazaki M.

Clin Pediatr Endocrinol. 2019;28(3):69-79. doi: 10.1297/cpe.28.69. Epub 2019 Jul 20.

19.

Melon GliSODin® Prevents Diet-Induced NASH Onset by Reducing Fat Synthesis and Improving Liver Function.

Nakamura A, Kitamura N, Yokoyama Y, Uchida S, Kumadaki K, Tsubota K, Watanabe M.

Nutrients. 2019 Aug 1;11(8). pii: E1779. doi: 10.3390/nu11081779.

20.

Volumetric growth rates of untreated vestibular schwannomas.

Schnurman Z, Nakamura A, McQuinn MW, Golfinos JG, Roland JT, Kondziolka D.

J Neurosurg. 2019 Aug 2:1-7. doi: 10.3171/2019.5.JNS1923. [Epub ahead of print]

PMID:
31374553
21.

Burosumab Improved Histomorphometric Measures of Osteomalacia in Adults with X-Linked Hypophosphatemia: A Phase 3, Single-Arm, International Trial.

Insogna KL, Rauch F, Kamenický P, Ito N, Kubota T, Nakamura A, Zhang L, Mealiffe M, San Martin J, Portale AA.

J Bone Miner Res. 2019 Aug 1. doi: 10.1002/jbmr.3843. [Epub ahead of print]

PMID:
31369697
22.

Enhancement of the Olfactory Response by Lipocalin Cp-Lip1 in Newt Olfactory Receptor Cells: An Electrophysiological Study.

Nakamura T, Noumi Y, Yamakawa H, Nakamura A, Wen D, Li X, Geng X, Sawada K, Iwasa T.

Chem Senses. 2019 Sep 7;44(7):523-533. doi: 10.1093/chemse/bjz048.

PMID:
31346612
23.

Which modifiable prenatal factors mediate the relation between socio-economic position and a child's weight and length at birth?

Ballon M, Botton J, Forhan A, de Lauzon-Guillain B, Melchior M, El Khoury F, Nakamura A, Charles MA, Lioret S, Heude B.

Matern Child Nutr. 2019 Oct;15(4):e12878. doi: 10.1111/mcn.12878. Epub 2019 Sep 3.

PMID:
31343839
24.

Creation of CRISPR-based germline-genome-engineered mice without ex vivo handling of zygotes by i-GONAD.

Gurumurthy CB, Sato M, Nakamura A, Inui M, Kawano N, Islam MA, Ogiwara S, Takabayashi S, Matsuyama M, Nakagawa S, Miura H, Ohtsuka M.

Nat Protoc. 2019 Aug;14(8):2452-2482. doi: 10.1038/s41596-019-0187-x. Epub 2019 Jul 24.

PMID:
31341289
25.

Influence of Timing of Insulin Initiation on Long-term Glycemic Control in Japanese Patients with Type 2 Diabetes: A Retrospective Cohort Study.

Miyazaki T, Shirakawa J, Nagakura J, Shibuya M, Kyohara M, Okuyama T, Togashi Y, Nakamura A, Kondo Y, Satoh S, Nakajima S, Taguri M, Terauchi Y.

Intern Med. 2019 Jul 22. doi: 10.2169/internalmedicine.3060-19. [Epub ahead of print]

26.

HER2-Positive Conversion in a Metastatic Liver Focus in Late Recurrent Breast Cancer.

Kitahara M, Hozumi Y, Nakamura A, Tachi K, Saitoh H, Iijima T.

Case Rep Oncol. 2019 Jun 26;12(2):473-479. doi: 10.1159/000501306. eCollection 2019 May-Aug.

27.

Aetiological Significance of Infectious Stimuli in Kawasaki Disease.

Nakamura A, Ikeda K, Hamaoka K.

Front Pediatr. 2019 Jun 28;7:244. doi: 10.3389/fped.2019.00244. eCollection 2019. Review.

28.

Gitelman's syndrome with hyperphosphatemia, effectively responding to single oral magnesium oxide administration: A case report.

Miya A, Nakamura A, Kameda H, Nozu K, Miyoshi H, Atsumi T.

Medicine (Baltimore). 2019 Jul;98(28):e16408. doi: 10.1097/MD.0000000000016408.

29.

A Novel Non-invasive Method for Predicting Liver Fibrosis by Quantifying the Hepatic Vein Waveform.

Soroida Y, Nakatsuka T, Sato M, Nakagawa H, Tanaka M, Yamauchi N, Wake T, Nakagomi R, Kinoshita MN, Minami T, Uchino K, Enooku K, Asaoka Y, Tanaka Y, Endo M, Nakamura A, Kobayashi T, Kurihara M, Hikita H, Sato M, Gotoh H, Iwai T, Fukayama M, Ikeda H, Tateishi R, Yatomi Y, Koike K.

Ultrasound Med Biol. 2019 Sep;45(9):2363-2371. doi: 10.1016/j.ultrasmedbio.2019.05.028. Epub 2019 Jul 12.

PMID:
31303401
30.

Does liberalisation of cannabis policy influence levels of use in adolescents and young adults? A systematic review and meta-analysis.

Melchior M, Nakamura A, Bolze C, Hausfater F, El Khoury F, Mary-Krause M, Azevedo Da Silva M.

BMJ Open. 2019 Jul 10;9(7):e025880. doi: 10.1136/bmjopen-2018-025880.

31.

Cross-cultural adaptation of the Chronic Illness Resources Survey in Japanese patients with diabetes.

Sato M, Miyoshi H, Nakamura A, Sumi N, Kamoshima H, Ono Y.

Jpn J Nurs Sci. 2019 Jul 10:e12279. doi: 10.1111/jjns.12279. [Epub ahead of print]

PMID:
31293065
32.

Factors with remission of fatty liver in patients with type 2 diabetes treated with ipragliflozin.

Yamauchi Y, Nakamura A, Takahashi K, Takase T, Yamamoto C, Yokota I, Atsumi T, Miyoshi H.

Endocr J. 2019 Jul 10. doi: 10.1507/endocrj.EJ19-0136. [Epub ahead of print]

33.
34.

Erratum: Publisher Correction: Calaxin is required for cilia-driven determination of vertebrate laterality.

Sasaki K, Shiba K, Nakamura A, Kawano N, Satouh Y, Yamaguchi H, Morikawa M, Shibata D, Yanase R, Jokura K, Nomura M, Miyado M, Takada S, Ueno H, Nonaka S, Baba T, Ikawa M, Kikkawa M, Miyado K, Inaba K.

Commun Biol. 2019 Jul 4;2:254. doi: 10.1038/s42003-019-0512-5. eCollection 2019.

35.

Age is an independent predictor in pathological diagnosis of sarcoidosis: a retrospective analysis of diagnosis by endobronchial ultrasound-guided transbronchial needle aspiration.

Kuwasaki E, Nagaoka T, Ihara H, Tsutsumi T, Nakamura A, Yoshikawa H, Yoshida T, Watanabe J, Ichikawa M, Koyama R, Shimada N, Takahashi K.

J Thorac Dis. 2019 May;11(5):2175-2180. doi: 10.21037/jtd.2019.01.94.

36.

Local Vibration Stimuli Induce Mechanical Stress-Induced Factors and Facilitate Recovery From Immobilization-Induced Oxidative Myofiber Atrophy in Rats.

Usuki F, Fujimura M, Nakamura A, Nakano J, Okita M, Higuchi I.

Front Physiol. 2019 Jun 20;10:759. doi: 10.3389/fphys.2019.00759. eCollection 2019.

37.

Effects of resistance-associated variants in genotype 2 hepatitis C virus on viral replication and susceptibility to antihepatitis C virus drugs.

Suda G, Kimura M, Shigesawa T, Suzuki K, Nakamura A, Ohara M, Kawagishi N, Nakai M, Sho T, Maehara O, Shimazaki T, Morikawa K, Natsuizaka M, Ogawa K, Sakamoto N.

Hepatol Res. 2019 Jul 1. doi: 10.1111/hepr.13401. [Epub ahead of print]

PMID:
31261439
38.

Entecavir treatment of hepatitis B virus-infected patients with severe renal impairment and those on hemodialysis.

Suzuki K, Suda G, Yamamoto Y, Furuya K, Baba M, Kimura M, Maehara O, Shimazaki T, Yamamoto K, Shigesawa T, Nakamura A, Ohara M, Kawagishi N, Nakai M, Sho T, Natsuizaka M, Morikawa K, Ogawa K, Sakamoto N; NORTE Study Group.

Hepatol Res. 2019 Jul 1. doi: 10.1111/hepr.13399. [Epub ahead of print]

PMID:
31260579
39.

Factors Relating to Caregivers' Preference for Advance Care Planning of Patients in Japan: A Cross-Sectional Study.

Shaku F, Tsutsumi M, Nakamura A, Takagi H, Otsuka T, Maruoka S.

Am J Hosp Palliat Care. 2019 Aug;36(8):727-733. doi: 10.1177/1049909119844517.

PMID:
31256612
40.

A Novel Approach for Investigating Upper Airway Hyperresponsiveness Using Micro-CT in Eosinophilic Upper Airway Inflammation such as Allergic Rhinitis Model.

Bui DV, Kanda A, Kobayashi Y, Sakata Y, Kono Y, Kamakura Y, Jinno T, Yun Y, Suzuki K, Sawada S, Asako M, Nakamura A, Dombrowicz D, Utsunomiya K, Noboru T, Tomoda K, Iwai H.

Biomolecules. 2019 Jun 27;9(7). pii: E252. doi: 10.3390/biom9070252.

41.

Pilot clinical study of ascorbic acid treatment in cardiac catheterization.

Sun L, Igarashi T, Tetsuka R, Li YS, Kawasaki Y, Kawai K, Hirakawa H, Tsuboi K, Nakamura AJ, Moritake T.

J Radiat Res. 2019 Jun 28. pii: rrz038. doi: 10.1093/jrr/rrz038. [Epub ahead of print]

PMID:
31251351
42.

High-throughput fluorescence polarization immunoassay by using a portable fluorescence polarization imaging analyzer.

Wakao O, Satou K, Nakamura A, Galkina PA, Nishiyama K, Sumiyoshi K, Kurosawa F, Maeki M, Ishida A, Tani H, Proskurnin MA, Shigemura K, Hibara A, Tokeshi M.

Lab Chip. 2019 Aug 7;19(15):2581-2588. doi: 10.1039/c9lc00256a. Epub 2019 Jun 28.

PMID:
31250849
43.

Calaxin is required for cilia-driven determination of vertebrate laterality.

Sasaki K, Shiba K, Nakamura A, Kawano N, Satouh Y, Yamaguchi H, Morikawa M, Shibata D, Yanase R, Jokura K, Nomura M, Miyado M, Takada S, Ueno H, Nonaka S, Baba T, Ikawa M, Kikkawa M, Miyado K, Inaba K.

Commun Biol. 2019 Jun 20;2:226. doi: 10.1038/s42003-019-0462-y. eCollection 2019. Erratum in: Commun Biol. 2019 Jul 4;2:254.

44.

Immunomodulatory and Metabolic Changes after Gnetin-C Supplementation in Humans.

Nakagami Y, Suzuki S, Espinoza JL, Vu Quang L, Enomoto M, Takasugi S, Nakamura A, Nakayama T, Tani H, Hanamura I, Takami A.

Nutrients. 2019 Jun 21;11(6). pii: E1403. doi: 10.3390/nu11061403.

45.

Case of endobronchial metastasis from breast cancer accompanied with Cunninghamella bertholletiae tracheobronchial mycetoma.

Uno K, Hishiya N, Matsuda M, Kai Y, Amano M, Nakamura A, Tohjyo T, Kawaguchi T, Nakano R, Yano H, Kasahara K, Mikasa K.

J Infect Chemother. 2019 Jun 18. pii: S1341-321X(19)30166-7. doi: 10.1016/j.jiac.2019.05.031. [Epub ahead of print]

PMID:
31227382
46.

Chain-Shortened Myostatin Inhibitory Peptides Improve Grip Strength in Mice.

Takayama K, Asari T, Saitoh M, Nirasawa K, Sasaki E, Roppongi Y, Nakamura A, Saga Y, Shimada T, Ikeyama H, Taguchi A, Taniguchi A, Negishi Y, Hayashi Y.

ACS Med Chem Lett. 2019 May 28;10(6):985-990. doi: 10.1021/acsmedchemlett.9b00174. eCollection 2019 Jun 13.

PMID:
31223459
47.

Proinsulin is sensitive to reflect glucose intolerance.

Nakamura A, Miyoshi H, Ukawa S, Nakamura K, Nakagawa T, Terauchi Y, Tamakoshi A, Atsumi T.

J Diabetes Investig. 2019 Jun 21. doi: 10.1111/jdi.13106. [Epub ahead of print]

48.

Assessing the risk of hepatocellular carcinoma by combining liver stiffness and the controlled attenuation parameter.

Izumi T, Sho T, Morikawa K, Shigesawa T, Suzuki K, Nakamura A, Ohara M, Kawagishi N, Umemura M, Shimazaki T, Kimura M, Nakai M, Suda G, Natsuizaka M, Ogawa K, Kudo Y, Nishida M, Ono K, Baba M, Furuya K, Sakamoto N.

Hepatol Res. 2019 Jun 20. doi: 10.1111/hepr.13391. [Epub ahead of print]

PMID:
31219667
49.

Nivolumab-induced hypophysitis causing secondary adrenal insufficiency after transient ACTH elevation.

Sekizaki T, Kameda H, Oba C, Yong Cho K, Nakamura A, Miyoshi H, Osawa T, Shinohara N, Atsumi T.

Endocr J. 2019 Jun 19. doi: 10.1507/endocrj.EJ19-0076. [Epub ahead of print]

50.

Effects of dapagliflozin and/or insulin glargine on beta cell mass and hepatic steatosis in db/db mice.

Omori K, Nakamura A, Miyoshi H, Takahashi K, Kitao N, Nomoto H, Kameda H, Cho KY, Takagi R, Hatanaka KC, Terauchi Y, Atsumi T.

Metabolism. 2019 Sep;98:27-36. doi: 10.1016/j.metabol.2019.06.006. Epub 2019 Jun 14.

PMID:
31202833

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