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S100B and its association with HIV-associated neurocognitive disorders.

Limpruttidham N, Mitchell BI, Kallianpur KJ, Nakamoto BK, Souza SA, Shiramizu B, Ndhlovu LC, Chow DC, Shikuma CM.

J Neurovirol. 2019 Jul 5. doi: 10.1007/s13365-019-00773-8. [Epub ahead of print] No abstract available.


Elevated cerebrospinal fluid Galectin-9 is associated with central nervous system immune activation and poor cognitive performance in older HIV-infected individuals.

Premeaux TA, D'Antoni ML, Abdel-Mohsen M, Pillai SK, Kallianpur KJ, Nakamoto BK, Agsalda-Garcia M, Shiramizu B, Shikuma CM, Gisslén M, Price RW, Valcour V, Ndhlovu LC.

J Neurovirol. 2019 Apr;25(2):150-161. doi: 10.1007/s13365-018-0696-3. Epub 2018 Nov 26.


Sleep and neuropsychological performance in HIV+ subjects on efavirenz-based therapy and response to switch in therapy.

Shikuma CM, Kohorn L, Paul R, Chow DC, Kallianpur KJ, Walker M, Souza S, Gangcuangco LMA, Nakamoto BK, Pien FD, Duerler T, Castro L, Nagamine L, Soll B.

HIV Clin Trials. 2018 Aug;19(4):139-147. doi: 10.1080/15284336.2018.1511348. Epub 2018 Nov 19.


Red blood cell distribution width as an easily measurable biomarker of persistent inflammation and T cell dysregulation in antiretrovirally treated HIV-infected adults.

Zhang Z, Chew GM, Shikuma CM, Gangcuangco LMA, Souza SA, Shiramizu B, Nakamoto BK, Gong T, Mannem SR, Mitchell BI, Kallianpur KJ, Ndhlovu LC, Chow DC.

HIV Clin Trials. 2018 Oct;19(5):172-176. doi: 10.1080/15284336.2018.1514821. Epub 2018 Nov 13.


Improved Cognitive Performance and Reduced Monocyte Activation in Virally Suppressed Chronic HIV After Dual CCR2 and CCR5 Antagonism.

DʼAntoni ML, Paul RH, Mitchell BI, Kohorn L, Fischer L, Lefebvre E, Seyedkazemi S, Nakamoto BK, Walker M, Kallianpur KJ, Ogata-Arakaki D, Ndhlovu LC, Shikuma C.

J Acquir Immune Defic Syndr. 2018 Sep 1;79(1):108-116. doi: 10.1097/QAI.0000000000001752.


Headaches More Common among Epilepsy Sufferers with Neurocysticercosis than Other Structural Brain Lesions.

Saito EK, Mehta B, Wang F, Nakamoto B, McMurtray AM.

Hawaii J Med Public Health. 2017 Jun;76(6):152-155.


Hemorrhagic Longitudinally Extensive Transverse Myelitis.

Wu CY, Riangwiwat T, Nakamoto BK.

Case Rep Neurol Med. 2016;2016:1596864. Epub 2016 Oct 25.


CNS Vasculitis Associated with Waldenström Macroglobulinemia.

Riangwiwat T, Wu CY, Santos-Ocampo AS, Liu RJ, McMurtray AM, Nakamoto BK.

Case Rep Neurol Med. 2016;2016:2510573. Epub 2016 Oct 12.


Comparative DNA Methylation Profiling Reveals an Immunoepigenetic Signature of HIV-related Cognitive Impairment.

Corley MJ, Dye C, D'Antoni ML, Byron MM, Yo KL, Lum-Jones A, Nakamoto B, Valcour V, SahBandar I, Shikuma CM, Ndhlovu LC, Maunakea AK.

Sci Rep. 2016 Sep 15;6:33310. doi: 10.1038/srep33310.


Non-classical monocytes predict progression of carotid artery bifurcation intima-media thickness in HIV-infected individuals on stable antiretroviral therapy.

Chow DC, Kagihara JM, Zhang G, Souza SA, Hodis HN, Li Y, Mitchell BI, Nakamoto BK, Kallianpur KJ, Keating SM, Norris PJ, Kohorn LB, Ndhlovu LC, Shikuma CM.

HIV Clin Trials. 2016 May;17(3):114-22. doi: 10.1080/15284336.2016.1162386. Epub 2016 Apr 4.


Surgical site infection: comparing surgeon versus patient self-report.

Pham JC, Ashton MJ, Kimata C, Lin DM, Nakamoto BK.

J Surg Res. 2016 May 1;202(1):95-102. doi: 10.1016/j.jss.2015.12.039. Epub 2015 Dec 30.


Oxidative mitochondrial DNA damage in peripheral blood mononuclear cells is associated with reduced volumes of hippocampus and subcortical gray matter in chronically HIV-infected patients.

Kallianpur KJ, Gerschenson M, Mitchell BI, LiButti DE, Umaki TM, Ndhlovu LC, Nakamoto BK, Chow DC, Shikuma CM.

Mitochondrion. 2016 May;28:8-15. doi: 10.1016/j.mito.2016.02.006. Epub 2016 Feb 23.


Non-Classical Monocytes and Monocyte Chemoattractant Protein-1 (MCP-1) Correlate with Coronary Artery Calcium Progression in Chronically HIV-1 Infected Adults on Stable Antiretroviral Therapy.

Zungsontiporn N, Tello RR, Zhang G, Mitchell BI, Budoff M, Kallianpur KJ, Nakamoto BK, Keating SM, Norris PJ, Ndhlovu LC, Souza SA, Shikuma CM, Chow DC.

PLoS One. 2016 Feb 11;11(2):e0149143. doi: 10.1371/journal.pone.0149143. eCollection 2016.


Serum amyloid P (SAP) is associated with impaired brachial artery flow-mediated dilation in chronically HIV-1 infected adults on stable antiretroviral therapy.

Zungsontiporn N, Ndhlovu LC, Mitchell BI, Stein JH, Kallianpur KJ, Nakamoto B, Keating SM, Norris PJ, Souza SA, Shikuma CM, Chow DC.

HIV Clin Trials. 2015 Nov;16(6):228-35. doi: 10.1179/1945577115Y.0000000007.


Early Childhood Vision Screening in Hawai'i Utilizing a Hand-Held Screener.

Chang DA, Ede RC, Chow DC, Souza RD, Gangcuangco LM, Hanks N, Nakamoto BK, Mitchell B, Masutani AT, Fisk S, Shikuma CM, Dill JE.

Hawaii J Med Public Health. 2015 Sep;74(9):292-6.


Symptoms of Autonomic Dysfunction in Human Immunodeficiency Virus.

Chow D, Nakamoto BK, Sullivan K, Sletten DM, Fujii S, Umekawa S, Kocher M, Kallianpur KJ, Shikuma CM, Low P.

Open Forum Infect Dis. 2015 Jul 8;2(3):ofv103. doi: 10.1093/ofid/ofv103. eCollection 2015 Sep.


Autonomic Function is Associated with Fitness Level in HIV-Infected Individuals.

Kocher MH, Hetzler RK, Shikuma CM, Kimura IF, Stickley CD, Lindsey RA, Nakamoto BK, Chow DC.

Jacobs J AIDS HIV. 2015 Jun;1(1). pii: 005.


Distal leg epidermal nerve fiber density as a surrogate marker of HIV-associated sensory neuropathy risk: risk factors and change following initial antiretroviral therapy.

Shikuma CM, Bennett K, Ananworanich J, Gerschenson M, Teeratakulpisarn N, Jadwattanakul T, DeGruttola V, McArthur JC, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiat P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N; SEARCH 003 protocol team.

J Neurovirol. 2015 Oct;21(5):525-34. doi: 10.1007/s13365-015-0352-0. Epub 2015 May 22.


Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort.

Parikh NI, Gerschenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN, Playford MP, Nakamoto BK, Seto TB, Chow DC, Shikuma CM.

Atherosclerosis. 2015 Mar;239(1):50-4. doi: 10.1016/j.atherosclerosis.2014.12.005. Epub 2014 Dec 20.


Past Cigarette Smoking Is More Common among Those with Cholinergic Than Noncholinergic Dementias.

Dalrymple K, Saito EK, Diaz N, Morrow J, Nakamoto B, McMurtray AM.

Neurol Res Int. 2014;2014:423602. doi: 10.1155/2014/423602. Epub 2014 Dec 10.


High rates of Native Hawaiian and older Japanese adults hospitalized with dementia in Hawai'i.

Sentell TL, Valcour N, Ahn HJ, Miyamura J, Nakamoto B, Chow D, Masaki K, Seto TB, Chen JJ, Shikuma C.

J Am Geriatr Soc. 2015 Jan;63(1):158-64. doi: 10.1111/jgs.13182. Epub 2014 Dec 23.


Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens.

Munger AM, Chow DC, Playford MP, Parikh NI, Gangcuangco LM, Nakamoto BK, Kallianpur KJ, Ndhlovu LC, Shikuma CM, Mehta NN.

AIDS Res Hum Retroviruses. 2015 Feb;31(2):221-8. doi: 10.1089/AID.2014.0239. Epub 2014 Dec 29.


Treatment intensification with maraviroc (CCR5 antagonist) leads to declines in CD16-expressing monocytes in cART-suppressed chronic HIV-infected subjects and is associated with improvements in neurocognitive test performance: implications for HIV-associated neurocognitive disease (HAND).

Ndhlovu LC, Umaki T, Chew GM, Chow DC, Agsalda M, Kallianpur KJ, Paul R, Zhang G, Ho E, Hanks N, Nakamoto B, Shiramizu BT, Shikuma CM.

J Neurovirol. 2014 Dec;20(6):571-82. doi: 10.1007/s13365-014-0279-x. Epub 2014 Sep 17.


Modeling promising nonmyeloablative conditioning regimens in nonhuman primates.

Chandrasekaran D, Nakamoto B, Watts KL, Kiem HP, Papayannopoulou T.

Hum Gene Ther. 2014 Dec;25(12):1013-22. doi: 10.1089/hum.2014.031.


Cost effective community based dementia screening: a markov model simulation.

Saito E, Nakamoto BK, Mendez MF, Mehta B, McMurtray A.

Int J Alzheimers Dis. 2014;2014:103138. doi: 10.1155/2014/103138. Epub 2014 Feb 6.


Monocytes expand with immune dysregulation and is associated with insulin resistance in older individuals with chronic HIV.

Shikuma CM, Chow DC, Gangcuangco LM, Zhang G, Keating SM, Norris PJ, Seto TB, Parikh N, Kallianpur KJ, Nakamoto BK, Nagamine LS, Ndhlovu LC, Barbour JD.

PLoS One. 2014 Feb 27;9(2):e90330. doi: 10.1371/journal.pone.0090330. eCollection 2014.


Reduced CD14 expression on classical monocytes and vascular endothelial adhesion markers independently associate with carotid artery intima media thickness in chronically HIV-1 infected adults on virologically suppressive anti-retroviral therapy.

Barbour JD, Jalbert EC, Chow DC, Gangcuangco LM, Norris PJ, Keating SM, Heitman J, Nagamine L, Seto T, Ndhlovu LC, Nakamoto BK, Hodis HN, Parikh NI, Shikuma CM.

Atherosclerosis. 2014 Jan;232(1):52-8. doi: 10.1016/j.atherosclerosis.2013.10.021. Epub 2013 Oct 31.


Poorer neuropsychological performance increases risk for social services among HIV-infected individuals.

Umaki TM, Gangcuangco LM, Chow DC, Nakamoto BK, Marotz L, Kallianpur KJ, Shikuma CM.

Hawaii J Med Public Health. 2013 Dec;72(12):422-6.


Diffuse leukoencephalopathy and subacute parkinsonism as an early manifestation of systemic lupus erythematosus.

Tse GG, Santos-Ocampo AS, Chow DC, McMurtray AM, Nakamoto BK.

Case Rep Neurol Med. 2013;2013:367185. doi: 10.1155/2013/367185. Epub 2013 Nov 28.


Feasibility and potential role of ferumoxytol-enhanced neuroimaging in HIV-associated neurocognitive disorder.

Nakamoto BK, Shikuma CM, Ogata-Arakaki D, Umaki T, Neuwelt EA, Shiramizu BT, Chow DC, Parikh NI, Kallianpur KJ, Hamilton BE.

J Neurovirol. 2013 Dec;19(6):601-5. doi: 10.1007/s13365-013-0213-7. Epub 2013 Oct 16.


The role of HIV and monocytes/macrophages in adipose tissue biology.

Shikuma CM, Gangcuangco LM, Killebrew DA, Libutti DE, Chow DC, Nakamoto BK, Liang CY, Milne CI, Ndhlovu LC, Barbour JD, Shiramizu BT, Gerschenson M.

J Acquir Immune Defic Syndr. 2014 Feb 1;65(2):151-9. doi: 10.1097/01.qai.0000435599.27727.6c.


IL-1Β enriched monocytes mount massive IL-6 responses to common inflammatory triggers among chronically HIV-1 infected adults on stable anti-retroviral therapy at risk for cardiovascular disease.

Jalbert E, Crawford TQ, D'Antoni ML, Keating SM, Norris PJ, Nakamoto BK, Seto T, Parikh NI, Shikuma CM, Ndhlovu LC, Barbour JD.

PLoS One. 2013 Sep 25;8(9):e75500. doi: 10.1371/journal.pone.0075500. eCollection 2013.


Greater frequency of depression associated with chronic primary headaches than chronic post-traumatic headaches.

McMurtray AM, Saito EK, Diaz N, Mehta B, Nakamoto B.

Int J Psychiatry Med. 2013;45(3):227-36.


Albuminuria as a marker of cardiovascular risk in HIV-infected individuals receiving stable antiretroviral therapy.

Tongma C, Shikuma CM, Nakamoto BK, Kallianpur KJ, Umaki TM, Barbour JD, Ndhlovu L, Parikh NI, Chow DC.

Hawaii J Med Public Health. 2013 Sep;72(9 Suppl 4):34-8.


Rates of autonomic dysfunction in HIV patients receiving antiretroviral therapy.

Chow D, Nakamoto B, So E, Parikh N, Souza S, Kallianpur K, Shikuma C.

J Neurovirol. 2013 Oct;19(5):511-2. doi: 10.1007/s13365-013-0198-2. Epub 2013 Sep 10. No abstract available.


Surfer's myelopathy: a radiologic study of 23 cases.

Nakamoto BK, Siu AM, Hashiba KA, Sinclair BT, Baker BJ, Gerber MS, McMurtray AM, Pearce AM, Pearce JW.

AJNR Am J Neuroradiol. 2013 Dec;34(12):2393-8. doi: 10.3174/ajnr.A3599. Epub 2013 Jul 4.


Predictors of 25-hydroxyvitamin D levels in HIV-infected patients in Hawai'i.

Gangcuangco LM, Chow DC, Liang CY, Nakamoto BK, Umaki TM, Kallianpur KJ, Shikuma CM.

Hawaii J Med Public Health. 2013 Jun;72(6):197-201.


Case of levodopa toxicity from ingestion of Mucuna gigantea.

Tse GG, Kim BB, McMurtray AM, Nakamoto BK.

Hawaii J Med Public Health. 2013 May;72(5):157-60. Review.


The effects of extended release niacin on lipoprotein sub-particle concentrations in HIV-infected patients.

Lin C, Grandinetti A, Shikuma C, Souza S, Parikh N, Nakamoto B, Kallianpur KJ, Chow D.

Hawaii J Med Public Health. 2013 Apr;72(4):123-7.


Coiled internal carotid arteries associated with bilateral sequential strokes.

Tse GG, Masuda EM, McMurtray AM, Nakamoto BK.

Case Rep Vasc Med. 2013;2013:929530. doi: 10.1155/2013/929530. Epub 2013 May 16.


Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter.

Kallianpur KJ, Shikuma C, Kirk GR, Shiramizu B, Valcour V, Chow D, Souza S, Nakamoto B, Sailasuta N.

Neurology. 2013 May 7;80(19):1792-9. doi: 10.1212/WNL.0b013e318291903f. Epub 2013 Apr 17.


The Impact of Depressive Symptoms on Neuropsychological Performance Tests in HIV-Infected Individuals: A Study of the Hawaii Aging with HIV Cohort.

Shimizu SM, Chow DC, Valcour V, Masaki K, Nakamoto B, Kallianpur KJ, Shikuma C.

World J AIDS. 2011 Dec 1;1(4):139-145.


Antiretroviral monocyte efficacy score linked to cognitive impairment in HIV.

Shikuma CM, Nakamoto B, Shiramizu B, Liang CY, DeGruttola V, Bennett K, Paul R, Kallianpur K, Chow D, Gavegnano C, Hurwitz SJ, Schinazi RF, Valcour VG.

Antivir Ther. 2012;17(7):1233-42. doi: 10.3851/IMP2411. Epub 2012 Sep 28.


Effects of antiretroviral therapy on autonomic function in early HIV infection: a preliminary report.

Chow D, Kocher M, Shikuma C, Parikh N, Grandinetti A, Nakamoto B, Seto T, Low P.

Int J Med Sci. 2012;9(5):397-405. doi: 10.7150/ijms.4441. Epub 2012 Jul 17.


Role of the veterans aging cohort study index in assessing total atherosclerotic burden.

Chow D, Thomas BS, Liang CY, Souza SC, Nakamoto BK, Parikh NI, Shikuma C.

Clin Infect Dis. 2012 Sep;55(5):750-1; author reply 751-2. doi: 10.1093/cid/cis537. Epub 2012 Jun 5. No abstract available.


Cerebrovascular risk factors and brain microstructural abnormalities on diffusion tensor images in HIV-infected individuals.

Nakamoto BK, Jahanshad N, McMurtray A, Kallianpur KJ, Chow DC, Valcour VG, Paul RH, Marotz L, Thompson PM, Shikuma CM.

J Neurovirol. 2012 Aug;18(4):303-12. doi: 10.1007/s13365-012-0106-1. Epub 2012 May 15.


Determinants of epidermal nerve fibre density in antiretroviral-naïve HIV-infected individuals.

Shikuma C, Gerschenson M, Ananworanich J, Valcour V, Teeratakulpisarn N, Jadwattanakul T, Degruttola V, Liang CY, McArthur J, Ebenezer G, Chomchey N, Praihirunkit P, Hongchookiath P, Mathajittiphun P, Nakamoto B, Hauer P, Phanuphak P, Phanuphak N; SEARCH 003 protocol team.

HIV Med. 2012 Nov;13(10):602-8. doi: 10.1111/j.1468-1293.2012.01024.x. Epub 2012 May 11.


Regional cortical thinning associated with detectable levels of HIV DNA.

Kallianpur KJ, Kirk GR, Sailasuta N, Valcour V, Shiramizu B, Nakamoto BK, Shikuma C.

Cereb Cortex. 2012 Sep;22(9):2065-75. doi: 10.1093/cercor/bhr285. Epub 2011 Oct 19.


Impact of cerebrovascular disease on cognitive function in HIV-infected patients.

Nakamoto BK, Valcour VG, Kallianpur K, Liang CY, McMurtray A, Chow D, Kappenburg E, Shikuma CM.

J Acquir Immune Defic Syndr. 2011 Jul 1;57(3):e66-8. doi: 10.1097/QAI.0b013e31821ff8bd. No abstract available.


Cardiovagal autonomic function in HIV-infected patients with unsuppressed HIV viremia.

Chow DC, Wood R, Choi J, Grandinetti A, Gerschenson M, Sriratanaviriyakul N, Nakamoto B, Shikuma C, Low P.

HIV Clin Trials. 2011 May-Jun;12(3):141-50. doi: 10.1310/hct1203-141.

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